Monika Salgueiro

University of the Basque Country | UPV/EHU · Departamento de Psicología Clínica y de la Salud y Metodología de Investigación

Background: Myasthenia gravis (MG) is an autoimmune neuromuscular disease characterized by fatigue and muscle weakness. Previous research has noted a high incidence of psychological problems, particularly anxiety and depression, as well as alterations in sleep quality among patients with MG. The aim of this study was to assess depression, anxiety,...

Background: Spina bifida (SB) is a rare congenital disease characterized by not only physical but also neuropsychological disturbances. Among these neuropsychological impairments, memory deficits are a significant concern, as they substantially hinder aspects of crucial importance in the lives of individuals with SB such as medical needs or daily l...

Myasthenia gravis (MG) is a neuromuscular disease of autoimmune etiology and chronic evolution. In addition to the muscle weakness and fatigue that characterize MG, in some studies patients show an inferior performance in cognitive tasks and difficulties in recognizing basic emotions from facial expressions. However, it remains unclear if these dif...

Chiari Malformation type I (CM-I) is a neurological disorder characterized by cerebellar tonsillar herniation. Chronic pain, particularly headaches, is a prevalent symptom in CM-I patients, significantly impacting their quality of life. The objective of this study was to evaluate the perceived quality of life in adults with CM-I and examine the inf...

Introducción: La Miastenia Gravis (MG) es una enfermedad neuromuscular autoinmune caracterizada por fatigabilidad y debilidad muscular, que puede manifestarse de forma generalizada o localizada. Los síntomas de este trastorno pueden agravarse debido a factores como el estrés, algunos medicamentos o el ejercicio físico. Investigaciones previas han r...

Objective: This study aimed to determine the effects of a neuropsychosocial teleassistance group-based intervention on improving social cognitive functioning and health-related quality of life (HRQoL) in pediatric neuromuscular diseases (NMD). Methods: Thirty-five pediatric patients with NMD were assigned to the neuropsychosocial intervention prog...

Chiari malformation has been classified as a group of posterior cranial fossa disorders characterized by hindbrain herniation. Chiari malformation type I (CM-I) is the most common subtype, ranging from asymptomatic patients to those with severe disorders. Research about clinical manifestations or medical treatments is still growing, but cognitive f...

The aim of this study was to compare the effects of the pandemic on health-related quality of life (HRQoL), anxious-depressive symptoms, feelings of loneliness, and fear of COVID-19 between people with myasthenia gravis (MG) and healthy controls. We also wanted to know in which group the variable fear of COVID-19 interfered the most with the result...

Introducción: La pandemia por COVID-19 ha afectado a la salud mental de la población mundial, pero poco se conoce sobre el impacto que ha generado en el estado psicológico de personas con enfermedades raras y crónicas. Este es el caso de la miastenia gravis (MG), una enfermedad neuromuscular autoinmune. El principal objetivo de este estudio consist...

Introducción: El Síndrome de Prader-Willi (SPW) es una enfermedad congénita que se caracteriza principalmente por hipotonía grave, hiperfagia, riesgo de obesidad durante la infancia y adolescencia, y discapacidad intelectual leve. El 33% de ellos presenta Trastorno del Espectro Autista (TEA), por lo que comparten cierta sintomatología conductual, c...

Caregivers’ emotions and finances are affected by the deterioration of functional capacity of patients with Duchenne muscular dystrophy (DMD), both in Mexico and Spain. Patient associations may reduce this impact on caregivers. This study aims to study the role of two models of associations, inspired by two different cultural models, in how the ser...

The main objective of this study is to identify fibromyalgia syndrome (FMS) clusters using the Revised Fibromyalgia Impact Questionnaire (FIQR); and to examine whether the clusters differ in sociodemographic characteristics, clinical measures, direct and indirect costs, levels of inflammatory markers and brain morphometry. A hierarchical cluster an...

Long-acting injectable (LAI) antipsychotics could be a favorable option of treatment and have some advantages over oral medications. The aim of this study was to review the published data on the use of LAI formulation of second-generation antipsychotics (SGA) in first-episode psychosis (FEP). Using PubMed and Scopus databases, we performed a system...

Perceived burdensomeness and thwarted belongingness are key factors in the development of suicidal behaviors that have been frequently observed among patients with fibromyalgia. The aim of the present study was to compare these two factors in patients with fibromyalgia with and without suicidal ideation and healthy subjects. Secondary objectives we...

According to the interpersonal theory of suicide, thwarted belongingness and perceived burdensomeness are key elements in the development of suicidal ideation. The Interpersonal Needs Questionnaire (INQ) was developed to assess the degree of frustration of these two interpersonal needs related to suicidal ideation. This study aims to analyze the ps...

Objectives: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. Its most prevalent manifestation is neuropsychiatric SLE (NP-SLE), which is characterized by increased involvement of the nervous system, with relevant symptoms, such as marked cognitive deficits, which are directly involved in subsequent functional disability. The obj...

In contrast with the recommendations of clinical practice guidelines, the most common treatment for anxiety and depressive disorders in primary care is pharmacological. The aim of this study is to assess the efficacy of a cognitive-behavioural psychological intervention, delivered by primary care psychologists in patients with mixed anxiety-depress...

Objective: To test the hypothesis that peripheral C nociceptor function may be abnormal in fibromyalgia and that C nociceptor dysfunction may contribute to the symptoms reported by these patients. Methods: Microneurography was used to record C nociceptors of 30 female patients meeting criteria for fibromyalgia and compared with recordings from 1...

The objective of this study was to evaluate the ability of artificial neural networks (ANNs) to predict, on the basis of clinical variables, the response of persons with fibromyalgia syndrome (FMS) to a standard, 4-week interdisciplinary pain program. The design of this study is retrospective longitudinal. Fibromyalgia outpatient clinic in a tertia...

The Revised version of the Fibromyalgia Impact Questionnaire (FIQR) was published in 2009. The aim of this study was to prepare a Spanish version, and to assess its psychometric properties in a sample of patients with fibromyalgia. The FIQR was translated into Spanish and administered, along with the FIQ, the Hospital Anxiety Depression Scale (HADS...

Opioid analgesia is compromised by intracellular mediators such as protein kinase C (PKC). The phosphatidylinositol hydrolysis-coupled serotonin receptor 5-HT2 is ideally suited to promote PKC activation. We test the hypothesis that 5-HT2A and 5-HT2B receptors, which have been previously shown to become pro-excitatory after spinal nerve ligation (S...

Clinical presentation of fibromyalgia syndrome (FMS) is heterogeneous and often involves psychological comorbidities. Clinical subgrouping of FMS patients has been proposed as a strategy to improve patients' long-term outcomes by helping identify specific treatment needs. Using the 90 Symptom Checklist Revised (SCL-90-R), we have assessed emotional...

Neurotransmitter serotonin (5-HT) released from descending pain modulation pathways to the dorsal horn is crucial to spinal nociception processing. This study sought to gain insight into the modulatory roles of specific serotonin receptor subtypes in experimentally induced neuropathic pain. In rats subjected to spinal nerve ligation (SNL) surgery,...

Introduction: Depression and anxiety are negative affective states that are often associated with chronic pain. In contrast, psychosocial factors such as social support influence pain perception and may contribute to the well being of chronic pain patients. Objectives: To evaluate the therapies received by patients with fibromyalgia syndrome (FMS)...

Introduction: Depression and anxiety are negative affective states that are often associated with chronic pain. In contrast, psychosocial factors such as social support infl uence pain perception and may contribute to the well being of chronic pain patients. Objectives: To evaluate the therapies received by patients with fi bromyalgia syndrome (FMS...

The depression rate of C fibre-evoked spinal field potentials by spinally applied morphine is increased in two states of spinal hyperexcitation, namely the spinal ligation model (SNL) of neuropathic pain and long-term potentiation (LTP) of C fibre-evoked spinal field potentials. This present work sought to determine opioid receptor subtypes involve...