Monika Radikė

• MD PhD
• Consultant at Liverpool Heart and Chest NHS Foundation Trust

Aim To explore barriers to academic activities that cardiovascular radiology-oriented radiology trainees face worldwide. Materials and methods An international call for participation in an online survey was distributed via social media and radiological societies to radiology trainees. Questions covered barriers and involvement in academic activi...

Background: Cardiothoracic ratio (CTR) in chest radiographs is still widely used to estimate cardiac size despite the advent of newer imaging techniques. We hypothesise that a universal CTR cut-off value of 50% is a poor indicator of cardiac enlargement. Our aim was to compare CTR with volumetric and functional parameters derived from cardiac magn...

Congenital heart disease is the most common group of congenital pathology. Over the past few decades, advances in surgical treatment have resulted in a rising population of adult patients with repaired complex congenital heart disease. Although the quality of life has greatly improved, a significant proportion of morbidities encountered in clinical...

Objectives: We performed a comprehensive assessment of the effect of myocardial ischemia duration on cardiac structural and functional parameters by serial cardiac magnetic resonance (CMR) and characterized the evolving scar. Background: CMR follow-up on the cardiac impact of time of ischemia in a closed-chest animal model of myocardial infarcti...

The Society for Cardiovascular Magnetic Resonance (SCMR) recommendations for training and competency of cardiovascular magnetic resonance (CMR) technologists document will define the knowledge, experiences and skills required for a technologist to be competent in CMR imaging. By providing a framework for CMR training and competency the overarching...

50 days open access until March 28th 2025: https://authors.elsevier.com/a/1kZWn,GNpk12dV Storage diseases are a diverse group of conditions marked by abnormal accumulations of substances like glycogen, fatty acids, and proteins in various tissues, including the heart and lungs. These rare diseases can pose significant diagnostic challenges due to...

Optimal management of adult congenital heart disease (ACHD) requires a multidisciplinary team (MDT) approach, fostering a collaborative culture over an individualistic approach. Within this framework, subspecialty-trained radiologists provide crucial imaging expertise, supporting cardiologists, surgeons, and interventional cardiologists in diagnose...

Pre-procedural imaging is critical for transcatheter mitral valve repair planning in patients with mitral valve disease. As differences among various measurement techniques for valve evaluation are still poorly understood, we sought to assess the intra- and interobserver agreement of complex measurements derived from a prototype mitral evaluation t...

Aims Recurrent acute myocardial infarction (RE-AMI) is a frequent complication after STEMI, and its association with stent thrombosis can be life-threatening. Intravenous atorvastatin (IV-atorva) administration during AMI has been shown to limit infarct size and adverse cardiac remodeling. We determined by cardiac magnetic resonance (CMR) whether t...

There is a wide and ever-increasing range of imaging indications for thoracic computed tomography (CT). Identifying and appropriately triaging cardiovascular findings is often challenging, especially in non-gated or unenhanced studies. The authors provide a pictorial review of clinically relevant abnormalities of the main intrathoracic vessels (aor...

Background Non-atherosclerotic causes of chest pain are challenging to diagnose, particularly in younger patients where coronary artery atherosclerosis is uncommon. Cardiac computed tomography (CT) has emerged as a valuable non-invasive imaging modality for assessing vascular wall and tissue characteristics. Objective Discuss the utility of cardia...

*** FULL TEXT - link valid until Sept 19, copy paste to your browser: https://authors.elsevier.com/c/1jWSH,GNpjzFGy *** Recreational drug abuse constitutes a serious health problem worldwide. Consumption of cocaine, amphetamine-type stimulants, opioids and cannabis can lead to multiple acute and chronic cardiopulmonary complications, resulting in...

Graphical abstract summarizing main study results.

Background and Aims The ecto–nucleoside triphosphate diphosphohydrolases of the CD39 family degrade ATP and ADP into AMP, which is converted into adenosine by the extracellular CD73/ecto-5-nucleotidase. This pathway has been explored in antithrombotic treatments but little in myocardial protection. We have investigated whether the administration of...

Coronary artery disease (CAD) diagnosis requires a precise assessment of patient profile and disease extension. While non-invasive imaging modalities offer an in-depth evaluation of CAD through differential approaches, this is based primarily on detecting coronary plaques or inducible myocardial ischaemia, thus each offering only a partial outlook...

Purpose To determine the reliability of the cardiothoracic ratio (CTR) as a simple method to assess the cardiac size and function in patients with non-ischemic cardiomyopathy (NICM). Methods In a sample of 91 patients (66 patients with diagnosed non-ischemic cardiomyopathy and 25 controls) we calculated the CTR on a posteroanterior chest radiograp...

50-day full access link https://authors.elsevier.com/a/1iQGf,GNpjzEP4 Pulmonary aspergillosis is a group of mycotic diseases affecting the lungs. The form of the disease mainly depends on the immune status of the patient and underlying conditions. Invasive pulmonary aspergillosis usually affects immunocompromised patients - angio-invasive and air...

Abstract AIM To review histologically confirmed diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) cases and carry out a detailed pathological–radiological correlation to see if computed tomography (CT) can be used to confidently identify DIPNECH. MATERIALS AND METHODS Twenty-three histologically confirmed DIPNECH patients in...

Background The aim of this study was to investigate willingness and barriers to academic activities of radiology trainees interested in interventional radiology subspecialty. Materials and methods Radiology trainees and fellows were called to participate a 35-question survey via online platforms and radiological societies. The research survey inve...

FULL TEXT LINK for 50 days: https://authors.elsevier.com/a/1g8HqcP6nBxh3 This study aimed to assess the factors of emigration and return among Lithuanian doctors practising abroad. A call for participation in an online survey was distributed via social media. Questions covered demographics, reasons to emigrate and factors that would favour returni...

Background Mitigating myocardial tissue injury (MTI) remains an unmet clinical need in the reperfusion era. Stimulating adenosine synthesis through the breakdown of adenosine triphosphate (ATP) by apyrase (CD39), an endothelial ADPase, has emerged as a potential new avenue in the reduction of MTI. Purpose In this study we examined whether the intr...

Background and Aims: Myocardial infarction (MI) is the clinical manifestation of atherosclerotic coronary artery disease. Spirulina is an algae known to ameliorate cardiometabolic disorders and with proven anti-inflammatory and anti-oxidant effects. We investigated, in a highly translatable animal model, whether oral supplementation with spirulina...

Cardiac sarcoidosis and cystic fibrosis (CF) are both rare conditions and their co-existence has not previously been noted in adults. For the first time we report a case of isolated cardiac sarcoidosis in a woman with CF, and discuss the possible combined aetiological factors. As the life expectancy of people with CF continues to increase, clinicia...

The Society for Cardiovascular Magnetic Resonance (SCMR) is an international society focused on the research, education, and clinical application of cardiovascular magnetic resonance (CMR). Case of the week is a case series hosted on the SCMR website (https://www.scmr.org) that demonstrates the utility and importance of CMR in the clinical diagnosi...

https://authors.elsevier.com/a/1doyc2GSKzBoZ

https://academic.oup.com/ehjcr/article/5/8/ytab256/6350056

Background Left ventricular (LV) pseudoaneurysm is a serious and rare complication of myocardial infarction (MI). It occurs when an injured myocardial wall ruptures and is contained by overlying adherent pericardium or scar tissue, most commonly it develops in patients with late presentation of MI and delayed revascularization. Case summary A 64-y...

A sixty-eight-year-old woman, a former smoker, presented to the Emergency department after twenty-four hours of malaise, sore throat and chest pain with a pleuritic component. https://scmr.org/page/COW2009 ISSN 2638-0994

Supplemental material is available for this article.

Background Preclinical and pilot human studies suggest platelet-independent cardioprotective effects of ticagrelor most likely due to its ability to block cellular uptake of adenosine. Adenosine is a potent endogenous protective molecule, concentrations of which locally rise as a response to ischemia because of the breakdown of extracellular ATP by...

https://scmr.org/page/COW2008

The mitral valve apparatus is one of the key structures of the heart with complex anatomy and function. The prevalence of mitral valve disease is associated with age: elderly people are affected more frequently. There are multiple inherited and acquired conditions; tumors may also involve the mitral valve. Stenosis and regurgitation are the main ma...

Objective HDL (high-density lipoprotein) role in atherosclerosis is controversial. Clinical trials with CETP-Inhibitors have not provided benefit. We have shown that HDL remodeling in hypercholesterolemia reduces HDL cardioprotective potential. We aimed to assess whether hypercholesterolemia affects HDL-induced atherosclerotic plaque regression. A...

Coronavirus disease 2019 (COVID-19) is a newly emerging human infectious disease that has quickly become a worldwide threat to health, mainly causing severe acute respiratory syndrome. In addition to the widely described respiratory syndrome, COVID-19 may cause life-treating complications directly or indirectly related to this infection. Among thes...

Background Beyond lipid-lowering, statins exert cardioprotective effects. High-dose statin treatment seems to reduce cardiovascular complications in high-risk patients. The ideal timing and administration regime remain unknown. Objectives This study compared the cardioprotective effects of intravenous statin administration during myocardial infarc...

European Heart Journal - Case Reports https://academic.oup.com/ehjcr/advance-article/doi/10.1093/ehjcr/ytaa034/5762450 Abstract Background Primary pericardial mesothelioma is a rare primary cardiac malignancy, with three main histopathological types, sarcomatoid histotype being the rarest. The imaging features were atypical due to concomitant...

Giant coronary artery aneurysm (CAAs) are unusual with reported incidence rate of 0.02% of patients who undergo cardiac surgery; often the proximal right coronary artery (RCA) is involved. They are defined as a localized area of dilatation exceeding 2cm in diameter. We report a case of an incidentally diagnosed partially thrombosed right CAA. A 69...

Objective: To investigate the presence of gender disparity in academic involvement during radiology residency and to identify and characterize any gender differences in perceived barriers for conducting research. Methods: An international call for participation in an online survey was promoted via social media and through multiple international...

To assess the involvement in research and teaching of radiology trainees who are interested in cardiovascular imaging and to identify the challenges they encounter. We distributed an online survey worldwide using social media and radiology societies that agreed to share it by the time of abstract submission. Factors affecting research and teaching...

UPDATE: The project has been published in 2021 as an article: https://authors.elsevier.com/a/1doyc2GSKzBoZ

Background Statins have shown to attenuate reperfusion-induced myocardial injury. However, whether statins directly target ischemia-related cardiac damage attenuating adverse left ventricular (LV) remodeling and post-myocardial infarction (MI) complications remains unknown. Purpose We examined the impact of a single intravenous administration of I...

Abstract is available online on ESGAR website ---> https://cslide.ctimeetingtech.com/esgar2019/attendee/person/610 Purpose: To identify barriers affecting academic involvement in research of radiology trainees with an interest in abdominal imaging during residency.

Full material is freely available online ---> https://posterng.netkey.at/esr/viewing/index.php?module=viewing_poster&task=viewsection&pi=151125&ti=546370&si=1800&searchkey=869397d15d296181b27e9cd41c71dd3b#poster <----- Introduction/Background: Inadequate involvement of radiology residents in research during core training has been reported in Europ...

http://imaging.onlinejacc.org/content/early/2019/05/09/j.jcmg.2019.03.021

📣 RAD RESIDENTS & FELLOWS 📣 Do you remember our survey investigating your involvement in Research? We have promising preliminary data🤓 Looking forward to sharing it very soon! THE SURVEY IS STILL OPEN for Radiology Residents & Fellows https://goo.gl/forms/x1rjfSvCLNVGjoVl1

Educational poster that describes radiologic features of pulmonary tuberculosis in patients with compromised immune system. Outline: 1. TB risk factors; 2. Patterns of pulmonary tuberculosis; 3. Tuberculosis and immunosuppression: HIV, Transplantation, Diabetes, Tumor necrosis factor inhibitors, Intensive care unit patients; 4. Paradoxical reactio...

Objectives: This study sought to investigate the association between the extent, location, and pattern of late gadolinium enhancement (LGE) and outcome in a large dilated cardiomyopathy (DCM) cohort. Background: The relationship between LGE and prognosis in DCM is incompletely understood. Methods: We examined the association between LGE and al...

Platelets are endowed with a repertoire of surface receptors that enable them to adhere, activate and aggregate upon vascular injury. Platelet adhesion is governed by the interaction between vascular collagen and GPIb-IX-V and GPVI-FcRγ complexes. Platelet kinases downstream 14–3-3ζ-bound GPIb and the FcRγ ITAM domain enable the activation of PLC-γ...

Aim To evaluate the relationship between sex, age and outcome in dilated cardiomyopathy (DCM). Methods and results We used proportional hazard modelling to examine the association between sex, age and all‐cause mortality in consecutive patients with DCM. Overall, 881 patients (290 women, median age 52 years) were followed for a median of 4.9 years...

Different inhaled substances, varying from gas, fumes, vapors and dust to liquid materials, can be the cause of inhalational lung injury. Inhaled substances may cause injury in pulmonary epithelium at various levels of respiratory tract, depending on the characteristics of the inhaled material, leading from simple symptoms to severe disease. Seve...

To evaluate the relationship between sex, age and outcome in dilated cardiomyopathy (DCM). We used proportional hazard modelling to examine the association between sex, age and all-cause mortality in consecutive patients with DCM. Overall, 881 patients (290 women, median age 52 years) were followed for a median of 4.9 years. Women were more likely...

We describe the case of a 66-year old woman with the extremely rare combination of sarcoidosis and amyloidosis (light chain) and the important role of cardiovascular magnetic resonance imaging to differentiate between these 2 infiltrative diseases. Myocardial characterization with T1 mapping can improve disease detection, especially in overlap case...

We describe the case of a 66-year old woman with the extremely rare combination of sarcoidosis-amyloidosis (light-chain) and the important role of cardiovascular magnetic resonance imaging to differentiate between these two infiltrative diseases. Myocardial characterization with T1 mapping can improve disease detection especially in overlap cases a...

Background The DANISH trial emphasised that the selection of patients with dilated cardiomyopathy (DCM) for implantable cardioverter defibrillators (ICD) needs to be improved. Registries demonstrate that the major burden of sudden cardiac death (SCD) occurs in those with a left ventricular ejection fraction (LVEF) >35%. Those at high-risk of SCD wi...

Background: Current guidelines only recommend the use of an implantable cardioverter defibrillator in patients with dilated cardiomyopathy for the primary prevention of sudden cardiac death (SCD) in those with a left ventricular ejection fraction (LVEF) <35%. However, registries of out-of-hospital cardiac arrests demonstrate that 70% to 80% of suc...

https://academic.oup.com/ehjcimaging/article/17/suppl_2/ii164/2963215

A 70-year-old diabetic female patient presented with fatigue, headaches, hallucinations and shivers following a history of sinusitis and ophthalmitis. She had an aortic surgery performed 7 years ago for a stenotic and regurgitant aortic valve with aneurysm of the ascending aorta. Work-up brain MRI revealed septic-embolic encephalitis. Multimodality...

Learning Objectives 1) To review the spectrum of lymphoid diseases affecting the small airways correlating CT imaging appearance with histopathologic features. 2) To provide an educational and structured framework for formulating a differential diagnosis. Background Bronchioles may be affected by lymphoid tissue disorders in a variety of clinica...