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Publications (34)
Pilot study: follow-up of patients examined in the Reference Center for Autism Spectrum Disorders in the year 2005-2006 Little is known about the long-term functioning, social inclusion and participation in society of patients diagnosed with an autism spectrum disorder (ASD) in childhood. Moreover, previous research mainly focuses on the impact of...
Background:
Little is known about patients with early onset psychosis (EOP) because of the low prevalence and separation of mental health care for adolescents and adults.
Aim:
To describe characteristics of patients with EOP, their global functioning and their journey concerning healthcare, education, employment status, living situation and well...
Emotion regulation (ER) has been identified as a transdiagnostic risk factor for psychopathology, making it an ideal target for prevention and treatment. This study explores how parents can nurture the development of child ER. In April 2022, a systematic review was executed focusing on malleable factors in the parental emotion-socialization process...
Emotional stress throughout the day is known to affect objective sleep physiology and subjective sleep quality. In the interplay between emotions and sleep, emotion regulation plays a critical role in the recovery from stressful, emotional events and subsequent sleep. While the effects of top-down emotion regulation strategies such as cognitive rea...
Cognitive control has two distinct modes - proactive and reactive (Braver, T. S. (2012). The variable nature of cognitive control: a dual mechanisms framework. Trends in Cognitive Sciences, 16(2), 105-112). ADHD has been associated with cognitive control impairments. However, studies have mainly focused on reactive control and not proactive control...
Cognitive deficits are critical features of bipolar disorder (BD), greatly impacting quality of life. The aim is to systematically review and critically evaluate underlying event related potential (ERP) features in euthymic BD relating to differences in sensory processes, attention, inhibition and conflict monitoring compared with healthy controls....
We are developing an interactive virtual underwater world with the aim to reduce stress and boredom in hospitalised children, to improve their quality of life, by employing an evidence-based design process and by using techniques from Artificial Life and Human-Computer Interaction. A 3D motion sensing camera tracks the activity of children in front...
Diminished responding to hearing one’s own name is one of the earliest and strongest predictors of autism spectrum disorder (ASD). Here, we studied, for the first time, the neural correlates of hearing one’s own name in ASD. Based on existing research, we hypothesized enhancement of late parietal positive activity specifically for the own name in n...
Objectives:
Patients with bipolar disorder (BD) are reported to have difficulties with inhibition, even in a euthymic state. However, the literature on cortical activity associated with response inhibition in BD remains ambiguous. This study investigates inhibition in euthymic BD using electrophysiological measures, while controlling for effects o...
This study reports the follow-up of 245 (12-to 17-year-old) adolescents exposed to antipsychotics, regardless of their diagnosis, including off-label use. Only 23 out of 245 patients had a prolactin value before starting on neuroleptics. Biometric data, the prolactin level and other hormones were monitored according to protocol. Insufficient data w...
Background:
Very little information is available concerning the prevalence of the use of medication for treatment of individuals with autism spectrum disorder (ASD), particularly in European countries. Earlier studies have shown that a large number of patients with ASD use at least one psychoactive drug and that the numbers are increasing. Even in...
Despite the large amount of literature on the treatment of feeding problems and disorders, it remains unclear which treatments are most effective. Hence, a systematic review was conducted of the literature on the outcome and effectiveness of interventions for the treatment of feeding problems and disorders in young children. A systematic literature...
16p11.2 microduplication is linked with a vulnerability for a range of psychiatric and somatic problems, with variable expression and penetration rate. We discuss the phenotypical expression of this microduplication with the case of a brother and sister. Both subjects went through child psychiatric diagnostics and treatment, where a varying degree...
Regular non-medical treatment of a 6-year-old female patient with autism spectrum disorder failed due to comorbid compulsions and hallucinations. Differential diagnosis included obsessive-compulsive disorder and psychosis. The patient's young age complicated accurate diagnosis and management. In this case we opted for a diagnostic follow-up, result...
•Prevention of cognitive decline was achieved in two siblings with CTX.•Clinical improvement in both systemic and neurological presentation of CTX.•Combination therapy with CDCA and atorvastatin is recommended for CTX.•A multidisciplinary approach is crucial to realize the best outcome.
In this chapter, we review empirical data and theoretical models which have been put forward in the affective science literature to account for the perception of emotions, when this process is simultaneously accomplished by sight and hearing. The visual component is provided by the face configuration that undergoes some geometric changes, which in...
The goal of the present study was to shed light on the respective contributions of three important action monitoring brain regions (i.e. cingulate cortex, insula, and orbitofrontal cortex) during the conscious detection of response errors. To this end, fourteen healthy adults performed a speeded Go/Nogo task comprising Nogo trials of varying levels...
The aim of the present study was to investigate whether error detection and subsequent regulatory processes could be influenced by pre-familiarisation with task-relevant stimulus features. To this end, 19 healthy adults performed a speeded Go/NoGo task with compound targets, involving two concurrent stimulus attributes, which were either pre-famili...
Twenty male adults with ADHD, 16 dyslexic adults, 15 comorbid adults, and 16 normal controls were compared on performance and underlying brain responses, during a cued Continuous Performance Test (O-X CPT), with the aim of discovering features of information processing differentiating between the groups. The study evaluated both cue- and target-rel...
Developmental dyslexia has been associated with reduced interhemispheric neural connectivity in children. The present study investigated functional interhemispheric connectivity in male dyslexic adults.
A group of 19 dyslexic men were compared to a group of 15 controls on interhemispheric coherence of the dominant frequency in the power spectrum du...
A visuo-spatial orienting task was used to investigate the individual and joint contribution of the presence of dyslexia and attention-deficit hyperactivity disorder (ADHD) to information processing.
Sixteen control, 17 dyslexic, 16 ADHD, and 15 comorbid adults performed the task, comprising a valid, invalid, and no-cue condition. Performance measu...
In dit proefschrift was het streven om overeenkomsten en verschillen in informatieverwerking tussen dyslexie en ADHD (aandachtstekortstoornis met of zonder hyperactiviteit) bij volwassenen bloot te leggen, waarbij onderscheid werd gemaakt tussen vroege perceptuele, centraal cognitieve, en late of aan reacties gerelateerde processen, die bestudeerd...
