Molines Arthur

Molines Arthur
University of California, San Francisco | UCSF · Department of Cell and Tissue Biology

PhD Cell Biology

About

16
Publications
685
Reads
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33
Citations
Introduction
Molines Arthur currently works at the Department of Cell and Tissue Biology, University of California, San Francisco.
Additional affiliations
February 2017 - present
University of California, San Francisco
Position
  • PostDoc Position
October 2013 - November 2016
Institute of Integrative Biology of the Cell (I2BC)
Position
  • PhD
Description
  • Plant Cell Biology Arabidopsis thalaian Cytoskeleton, Microtubules, EB1, MAP65-1 Microscopy, Image Analysis
October 2013 - present
Université Paris-Sud 11
Position
  • Professor
Description
  • Plant Sciences, 35 hrs / year, bachelor Image Processing, 15 hrs / year, master
Education
September 2011 - June 2013
Université Paris-Sud 11
Field of study
  • Plant Sciences
September 2008 - June 2011
Paris Diderot University
Field of study
  • Cell Biology and Physiology

Publications

Publications (16)
Preprint
The cytoplasm is a complex, crowded, actively-driven environment whose biophysical characteristics modulate critical cellular processes such as cytoskeletal dynamics, phase separation, and stem-cell fate. Little is known about the variance in these cytoplasmic properties. Here, we employed particle-tracking nano-rheology on genetically encoded mult...
Article
Full-text available
The cytoplasm is a crowded, visco-elastic environment whose physical properties change according to physiological or developmental states. How the physical properties of the cytoplasm impact cellular functions in vivo remains poorly understood. Here, we probe the effects of cytoplasmic concentration on microtubules by applying osmotic shifts to fis...
Article
Full-text available
Objective: Most eukaryotic cells contain microtubule filaments, which play central roles in intra-cellular organization. However, microtubule networks have a wide variety of architectures from one cell type and organism to another. Nonetheless, the sequences of tubulins, of Microtubule Associated proteins (MAPs) and the structure of microtubules a...
Preprint
Full-text available
The cytoplasm represents a crowded environment whose properties may change according to physiological or developmental states. Although the effects of crowding and viscosity on in vitro reactions have been well studied, if and how the biophysical properties of the cytoplasm impact cellular functions in vivo remain poorly understood. Here, we probed...
Preprint
Full-text available
Objective Most eukaryotic cells contain microtubule filaments, which play central roles in intra-cellular organization. However, microtubule networks have a wide variety of architectures from one cell type and organism to another. Nonetheless, the sequences of tubulins, of Microtubule Associated proteins (MAPs) and the structure of microtubules are...
Preprint
Full-text available
Objective Most eukaryotic cells contain microtubule filaments, which play central roles in intra-cellular organization. However, microtubule networks have a wide variety of architectures from one cell type and organism to another. Nonetheless, the sequences of tubulins, of Microtubule Associated proteins (MAPs) and the structure of microtubules are...
Article
Full-text available
Microtubules are involved in plant development and adaptation to their environment, but the sustaining molecular mechanisms remain elusive. Microtubule-end-binding 1 (EB1) proteins participate in directional root growth in Arabidopsis thaliana. However, a connection to the underlying microtubule array has not been established yet. We show here that...
Article
Full-text available
Microtubules are involved in plant development and adaptation to their environment, but the sustaining molecular mechanisms remain elusive. Microtubule-end-binding 1 (EB1) proteins participate in directional root growth in Arabidopsis thaliana. However, a connection to the underlying microtubule array has not been established yet. We show here that...
Thesis
Les microtubules sont des filaments protéiques dynamiques, essentiels au bon fonctionnement de la plupart des cellules eucaryotes. L’organisation de ce réseau de fibres constitue un enjeu majeur pour la cellule, puisque c’est de cette organisation que découle une grande partie de ses fonctions. Dans les cellules animales, la protéine EB1 (End Bindi...

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Projects

Projects (2)
Archived project
Studying the role of the EB1 proteins in microtubules dynamics, bundling and network organization in plants.
Project
Little is known about how the crowded environment of the cytoplasm affects molecular processes within the cell. The cell often encounters changes in cytoplasmic density, for instance in the course of the normal cell cycle as well as in response to environmental changes. For instance, changes in osmolarity leads to loss of intracellular volume through loss of water. In vitro studies predict that molecular crowding may speed up processes such as microtubule polymerization...