Mokhamad Fakhrul Ulum

Bogor Agricultural University | IPB · Department of Veterinary Clinic, Reproduction and Pathology

This study aims to observe wicking and separation characteristics of blood plasma in cotton thread matrix functioning as a microfluidic thread-based analytical device (µTAD). We investigated several cotton thread treatment methods using Ethylenediaminetetraacetic acid (EDTA) anticoagulant solution for wicking whole blood sample and separating its p...

An in vivo study is one of the most important steps in the process of translating biomaterials to clinical applications. It is mostly conducted to confirm in vitro results before going further to clinical trials. Appropriate use of animal models in the in vivo studies of biomaterials and medical devices is mandatory and should meet the approved reg...

Background/Objective: Hydrogen gas cavity is formed during in vivo degradation of magnesium implants. In many studies, the gas cavity is mostly punctured out subcutaneously. However, this procedure becomes inapplicable in certain internal surgeries; therefore, the effect of this gas cavity is worth further assessment. Methods: In this study, we inv...

Iron-bioceramic composites have been developed as biodegradable implant materials with tailored degradation behavior and bioactive features. In the current work, in vivo bioactivity of the composites was comprehensively studied by using sheep animal model. Five groups of specimens (Fe-HA, Fe-TCP, Fe-BCP composites, and pure-Fe and SS316L as control...

Biodegradable metals such as magnesium, iron and their alloys have been known as potential materials for temporary medical implants. However, most of the studies on biodegradable metals have been focusing on optimizing their mechanical properties and degradation behaviour with no emphasis on improving their bioactivity behaviour. We therefore inves...

Rosyada ZNA, Yoelinda VT, Kaiin EM, Gunawan M, Ulum MF, Tumbelaka LITA, Solihin DD, Agil M, Gunawan A, Purwantara B. 2023. Sperm osteopontin mRNA expression levels and its correlation on semen quality and fertility in Madura bulls. Biodiversitas 24: 563-570. Osteopontin (OPN) gene transcripts influence spermatogenesis and germ cell development. The...

Background and Aim: The quality of frozen bull sperm after thawing is influenced by the primary diluent and antioxidant. This meta-analysis was conducted to determine the effect of supplementing L-cysteine and its group analogs on the quality of frozen bull sperm. Materials and Methods: A total of 22 articles obtained from Google Scholar and Scopus...

Nowadays, selection of superior male candidates in livestock as a source of frozen semen based on sperm quality at the cellular level is not considered accurate enough for predicting the potential of male fertility. Sperm transcriptome analysis approaches, such as messenger RNA levels, have been shown to correlate with fertility rates. Using this t...

Heat shock protein 70 (HSP70) is one of the most abundant chaperone proteins. Their function is well documented in facilitating the protein synthesis, translocation, de novo folding, and ordering of multiprotein complexes. HSP70 in bovine consists of four genes: HSP70-1, HSP70-2, HSP70-3, and HSP70-4. HSP70-2 was found to be involved in fertility....

Over the past 5 years, many works have been performed to reveal the potentials of Zinc (Zn)-based materials as temporary bone scaffolds with the expectation that their emergence could address some of the main concerns associated with magnesium- and iron-based materials. Thanks to the emerging Additive Manufacturing (AM) technology, it facilitates t...

The objective of this study was to evaluate single nucleotide polymorphisms (SNP) in the 3'UTR region of CAPN1 gene by direct sequencing technique in beef cattle and its influence on growth and meat quality of the contrast mode ultrasound image in Bali cattle. The numbers of beef cattle used were Bali cattle (n=52 heads) which compared to purebred...

Electrical impedance tomography (EIT) is a non-invasive technique for imaging the electrical conductivity and permittivity in the body by measuring the electrical potential on the surface. One of the EIT applications in the medical field is breast cancer detection. The study proposed a rectangular geometry EIT multi-frequency device based on the Fi...

Pengekangan merupakan langkah awal dan utama dalam menentukan keberhasilan untuk pemeriksaan hewan, seperti pada pencitraan ultrasonografi. Tulisan ini mendeskripsikan beberapa metode pengekangan sapi bali untuk pencitraan ultrasonografi di kandang penampungan dan pola sonogram yang didapatkan. Sapi bali jantan dewasa sebanyak 101 ekor dilakukan pe...

Madura bulls are Indonesian germplasm with a very high capacity to adapt to dry environments. Madura bulls come from a crossbreed between Zebu ( Bos indicus ) and banteng ( Bos javanicus ). One of the breeding strategies of Madura cattle is the use of artificial insemination (AI) with frozen semen. Regarding sperm motility as one of the standard pa...

Ultrasonography (US) and Electrical Impedance Tomography (EIT) can be used to detect breast cancer. Ultrasonography is based on non-ionizing radiations without adverse biological effects. A set of electrodes was placed around the torso and a small alternating current (AC) was injected via two of the electrodes into the object. This study aimed to a...

Iron (Fe) & Fe-based materials have been vigorously explored in orthopedic applications in the past decade mainly owing to their promising mechanical properties including high yield strength, elastic modulus & ductility. Nevertheless, their corrosion products & low corrosion kinetics are the major concerns that need to be improved further despite t...

Bali cattle ( Bos javanicus ) are native Indonesian cattle, domesticated from banteng ( Bibos banteng ). Genes that have an important role in meat quality are calcium-activated neutral protease genes, known as calpains (CAPN). The objective of this study was to evaluate the polymophisms of calpain gene SNP g.232 G>T by PCR-RFLP technique and its in...

Bali cattle ( Bos javanicus ), as Indonesian origin genetic resources, is domesticated from banteng (Bibos banteng). Bali cattle have the potential to be developed as producer of premium beef. Genes that have important role in meat quality are calcium-activated neutral protease genes, as known as calpains (CAPN). Calpains are classified as Ca ²⁺ de...

Prolaps vagina umumnya terjadi pada sapi bunting trimester ketiga, namun juga dapat terjadi pada sapi tidak bunting. Tulisan ini melaporkan kasus prolaps vagina pada sapi tidak bunting tiga bulan pasca partus. Sapi mengalami demam, peningkatan frekuensi napas, dan mukosa vagina tampak keluar dari vulva. Sapi ditangani dengan membersihkan mukosa vag...

Determining double muscle based on the myostatin (MSTN) gene in Belgian blue (BB), Peranakan Ongole (PO) and BB × PO crossbred cattle is very important for crossbreeding programs. This study aimed to investigate single-nucleotide polymorphisms (SNPs) and 11-bp deletions in the coding region of the MSTN gene and their relationship with the double-mu...

Background and aim: Ultrasonography (USG) is useful for non-invasively identifying changes that occur in soft tissue architecture. The objective of this research was to demonstrate postpartum (PP) uterine involution through the changes of perineal muscle intensity and thickness in Madura beef cow by ultrasonography. Materials and methods: Madura...

Electrical Impedance Tomography (EIT) has an advantage than another imaging systems in the medical field, they are safe, fast, and simple. The role of EIT is promising, so that it is necessary to develop electrical impedance tomography devices, especially in the biomedical field. we have successfully constructed a multi-frequency EIT system for bio...

The hematocrit value test serves as a parameter to help reach an established diagnosis. A centrifuge is an equipment that is used to separate the components of blood from each other based on the properties of each constituent substance. This study aims to developing hand-powered centrifuge made from cotton material to assess the hematocrit of blood...

Citra radiografi suatu objek yang diperoleh dari mesin x-ray analog adalah berupa film yang telah tercetak sebagai suatu gambar dengan gradasi warna hitam, abu dan putih yang disebut sebagai opasitas. Penilaian perubahan opasitas pada film hasil radiografi analog dilakukan dengan bantuan lampu illuminator untuk menampilkan citra dari objek. Identif...

Evaluation of genetic factors such as heritability value and non genetic factors of reproductive traits has a vital role in improving breeding and management practices of beef cattle. The aim of the present study was to evaluate heritability value and non-genetic factors affecting reproductive traits in Ongole grade cattle. Five hundred and fifty-t...

The conventional anatomical study of specimens requires cutting processes which destruct the limited specimens. A non‐destructive method, namely an ultrasonography, can be used to assess the anatomical organ information of those specimens. The aim of this research is to analyse the macroanatomy of the female reproductive organ in the Sunda porcupin...

Jakaria, Ulum MF, Lestari D, Akwila S, Sihite DEWT, Priyanto R, Muladno, Sumantri C. 2020. Investigating new SNPs of CAST, CAPN and SCD genes in 5’UTR of Bali cattle. Biodiversitas 21: 2971-2976. The present investigation aims to explore specific SNPs of Bali cattle, focusing mainly on CAST, CAPN, and SCD genes in 5'UTR. DNA of Bali cattle (25 indi...

Bali cattle are one of the native cattle breeds in Indonesia as a meat producer. The objective of this study was to analyze the correlation between body weight and scrotal circumference and sperm quantity of Bali bulls. To accomplish this objective, primary and secondary data of Bali bulls in Baturiti Artificial Insemination (AI) Center, Bali from...

Friesian Holstein bull (FH) is one of dairy cattle in Indonesia. It is important to increase the production of dairy cattle to meet the need for milk consumption. The way to develop is through artificial insemination (AI). This study was aimed to evaluate the FH bull fertility by calculating the percentage of first service conception rate (%FSCR) o...

Hydroxyapatite-chitosan (HAp-chitosan) composites can be synthesized into injectable bone substitute by adding hydroxypropyl methylcellulose (HPMC) as a suspending agent. This material allows the filling of empty cavities due to osteoporosis. The purpose of this experiment was to synthesize, to characterize, and to measure the viscosity, contact an...

This study aimedto identify the SNP g.643G>Aof MYF5 genethen associate it with body weight and body size measurements in Bali cattle. Blood samples were collectedfrom 80 bali cattle at BPTU-HPT Denpasar Bali. Data on phenotypic properties observed included; birth weight, live weight, average daily gain, body length, chest depth, withers height, hip...

Aim: This study aimed to analyze the individual factors influencing the sperm quality of Bali bulls at Baturiti Artificial Insemination (AI) center. Materials and methods: Semen that was ejaculated from nine Bali bulls was collected using artificial vaginas (n=5/bull). Semen ejaculates were evaluated immediately after collection to measure the q...

Background and aim: Holstein cows and heifers are widely bred in Indonesia by artificial insemination (AI) to increase population and milk production. Sperm fertility is modulated by genetic factors, but the analysis of sperm quality is still based on macro- and microscopic characteristics. This study aimed to analyze both sperm quality and protei...

The purpose of this study was to determine the diversity of qualitative traits in PO, Belgian Blue and PO-Belgian Blue crosses using principal component analysis. The total samples of cattle used were 36 consisting of 8 heads Belgian Blue (4 males and 4 females), 17 heads Belgian PO-Belgian cross-breed (11 males and 6 females) and 11 PO heads (all...

ABSTRAK. Tujuan penelitian ini adalah mengevaluasi kinerja pertumbuhan sapi persilangan Belgian Blue (BB) dan sapi Peranakan Ongole (PO) pada turunan pertama (F1). Sapi persilangan (BB dan PO) yang digunakan sebanyak 15 ekor terdiri atas jantan 6 ekor dan betina 9 ekor, selain itu digunakan 8 ekor sapi PO betina yang dipelihara di Balai Embrio Tern...

Absorbable metals have been introduced as materials to fabricate temporary medical implants. Iron, magnesium and zinc have been considered as major base elements of such metals. The metallurgical characterization and in-vitro corrosion assessment of these metals have been covered by the new ASTM standards F3160 and F3268. However, the in-vivo corro...

Ekokardiografi merupakan salah satu teknik diagnosis kesehatan organ jantung dengan memanfaatkan gelombang suara berfrekuensi tinggi yang bersifat non-invasif, aman, cepat, dan mudah dilakukan. Penelitian ekokardiografi ini bertujuan untuk mengamati struktur, ukuran, dan posisi organ jantung pada tiga spesies sanca, yaitu Sanca batik, Sanca bodo, d...

Ultrasonography is a diagnostic method to image the conditions of reproductive organs and it could be supported by vaginal cytology to identify the activities of the ovaries by the types of vaginal exfoliate cells. The aims of this study was to observe reproduction organ through ultrasonography with supportive diagnostic with vaginal cytological as...

Prolaps organ reproduksi vagina pada sapi perah jarang terjadi dan belum banyak dilaporkan. Prolaps vagina harus ditangani dengan segera untuk mencegah terjadinya infeksi sekunder yang mengganggu siklus reproduksi. Tulisan ini melaporkan kasus prolaps vagina yang ditemukan di peternakan rakyat, anggota Koperasi Peternak Sapi Bandung Utara (KPSBU),...

Landak jawa (Hystrix javanica) memiliki keunikan pada rambutnya yang termodifikasi menjadi duri. Duri pada landak berperan sebagai pertahanan diri dari predator. Penanganan dan pengekangan landak cukup sulit dilakukan sehingga pengambilan data biologi ladak jawa menjadi terbatas. Penanganan dan pengekangan secara kimiawi menggunakan sediaan bius um...

Kasus nefrolithiasis ini ditemukan pada seekor red eared slider (RES) atau di Indonesia dikenal dengan nama kura-kura Brazil, secara tidak disengaja ketika hewan tersebut diperiksa secara radiografi untuk melihat morfologi normalnya. Kura-kura telah dipelihara selama satu tahun oleh pemilik tanpa ada keluhan apapun. Kura-kura tersebut dipelihara di...

Abses merupakan kasus yang sering terjadi pada jaringan kulit gajah. Seekor gajah Sumatera dewasa mengalami kebengkakan pada jaringan otot di sekitar tuber ischii, sedangkan anak gajah mengalami kebengkakan di daerah sekitar vagina. Gajah dikekang dan ditangani oleh keeper menggunakan tali dan rantai. Pemeriksaan klinis dilakukan oleh dokter hewan...

The examination of udder through a parameter such as parenchymal tissue (PAR) and mammary fat pads (MFP) can be used to evaluate health status and the development of mammary gland. This research was conducted to evaluate the PAR and MFP of Murrah (n=4) and Swamp (n=4) buffalo heifer calve udder using brightness-mode ultrasonography transcutaneously...

This study was to establish quantitative reference range measurements that could be used to support basic data of cardiac size in the laboratory animals. Right and left lateral recumbency (R/L view) and ventral and dorsal recumbency (VD/DV view) radiographs were obtained in 6 normally laboratory mice ( Mus musculus ). The R/L view heart measurement...

Background The change in size and weight of the female reproductive organs during gestation and birth might be affect the perineal muscles and this condition in dairy cow not been reported. This study aimed to assess the ultrasonographic image of coccygeus muscle in 11 inseminated dairy cows with different gestational ages and postpartum. Methods...

This study aims to delineate the tissue structure of male cat external reproductive organs using ultrasound with different types of consoles and transducers frequencies through indirect method. External organ of 5 tom weighing 2-3 kg was evaluated using ultrasound with stationary console (linear transducer, 10 MHz) and portable console (linear tran...

Teknologi pencitraan ultrasonografi memiliki peranan penting dalam manajemen kesehatan pada ular sanca. Struktur sistem organ di dalam tubuh seperti hepatobiliari dapat dipantau secara non-invasif menggunakan teknologi ultrasonografi. Citra ultrasonografi organ hepatobiliari pada tiga spesies ular sanca, yang terdiri atas sanca batik, sanca bodo, d...

Chemical castration is a method that can be applied easily without any surgical intervention in animals. This study utilized iron (III) chloride hexahydrate (FeCl3.6H2O) as a new material for chemical castration in mice. Twenty seven adult male mice were divided into five groups: FeCl3 20% (n = 6), FeCl3 10% (n = 6), FeCl3 5.0% (n = 6), FeCl3 2.5%...

The purpose of this study was to investigate Indonesian stray cat (KLI) eyes by transpalpebrae B-mode ultrasound imaging. Eight healthy adult stray cats with 3.0-4.0 kg body weight were underwent of eyes ultrasound scanning without anesthesia or sedation. Linear ultrasound transducer with 7.5-15 MHz of frequency and ultrasound-gel were adhered dire...

This paper reports a series of in vitro, ex vivo and in vivo mechanical and corrosion studies of pin and screw prototype made of friction welded pure iron and 316L type stainless steel aiming to evaluate the applicability of the partially removable bone screws. Results showed that the pin possesses bending, tensile and torsional strengths of 1706±1...

One of important aspects in bone healing process is physiological level of calcium (Ca), and phosphorus (P) that can be altered by implantation of biodegradable porous iron. Therefore, this study aims to investigate the concentration of Ca, P and Ca/P ratio in the peripheral blood during the implantation period up to 4 months. Forty adult male Spra...

The objective of this study were to predict carcass quality characteristics in Bali cattle using ultrasound imagery. The Number of samples were 81 heads of Bali cattle consist of bulls (62 heads) and cows (19 heads) with various age ranging from 1 to 6 years were collected their body weight and carcass qualities including backfat thickness (BF), lo...

The aim of this study was to describe the role of diagnostic imaging and endoscopy to define the diagnose of the upper gastrointestinal tract disorder of the Schnauzer. The information from the owner stated that the dog has been vomiting for a year, sometimes containing blood. There might also be a possibility that it had eaten a corpus alienum. Th...

The interaction of biomaterials with the human body not only affects the surrounding implantation tissue but also the integrity of biomaterial itself. The body fluid that contains aggressive chloride ions can trigger degradation of metallic biomaterials, leading to the release of metal ions and the formation of degradation products. This natural re...

Myostatin (MSTN) gene plays a key role in skletal muscle homeostasis such as inducing muscle athrophy, poliferation of myoblast, increasing ubiquitin-proteasomal, downregulating IGF pathway, and glucolysis. Myostatin gene expression is controled by CpG island located in promoter region. The objectives of this research were to identify polymorphism...

Pada studi kasus ini kami mendokumentasikan sebuah kasus prolapsus kantung pipi pada seekor hamster mini Campbell ( Phodopus campbelli ). Hamster mini Campbell datang dengan anamneses adanya sebuah massa di kiri mulut bagian dalam yang tampak menyembul keluar. Berdasarkan pemeriksaan klinis, hamster mengalami prolapsus kantung pipi dengan prognosa...

p>Pengukuran tekanan darah sistolik (TDS) dan saturasi oksigen (SpO2) merupakan salah satu cara pemantauan fungsi kardiovaskular untuk mengetahui resiko gangguan jantung. Tujuan penelitian ini adalah untuk mengamati dinamika TDS dan SpO2 domba garut pada pagi dan siang hari dengan variasi suhu kandang. Penelitian ini menggunakan 4 ekor domba garut...

Benang jahit bedah merupakan biomaterial implan polimer yang lazim digunakan untuk penjahitan jaringan dalam tindakan bedah. Bahan baku baru dari sutera alam yang dihasilkan ulat sutera Attacus atlas Linn. (A. atlas) sebagai benang jahit bedah dilakukan pengujian pada toksisitas secara in-vitro pada sel otot polos tikus dan uji in-vivo pada hewan m...