Mohmed Isaqali Karobari

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Verified

Mohmed verified their affiliation via an institutional email.

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• BDS. MDSc Endodontics. PhD Endodontics. FDS RCS (Eng). FPFA. FICD. MFDS RCPS (Glasg).
• Professor at Saveetha University

This cone beam computed tomography (CBCT) study aimed to evaluate the root canal morphology of permanent anteriors in Malaysian population using two classification systems (Vertucci 1984 and Ahmed et al 2017). CBCT images of 856 patients with 10,080 anterior teeth were analysed. Results showed that, except for six mandibular canines, all anterior t...

Background The clinician should have complete knowledge of the normal anatomy of the root as well as complexities in the root canal configuration for a better outcome, as missed or improper handling of the canal system can lead to the failure of an entire endodontic procedure. The present study aims to assess the morphology of roots and canals in p...

Introduction Mandibular first premolars are familiar with their varied root canal morphology, causing difficulties and challenges for successful endodontic procedures. This systematic review and meta-analysis aim to study the characterization of root and canal morphology of the first mandibular premolar using micro-computed tomography. Methodology...

Purpose: To assess the application and accuracy of two systems (Vertucci et al 1974 and Ahmed et al. 2017) in classifying the root and canal morphology of human dentition amongst final year undergraduate, interns, and postgraduate dental students in India. Methods: The survey was conducted using physical and online presentation modes in two phases....

Background Effective adhesion between dentin and resin materials is essential for the long-term durability of onlays, as the strength and durability of the tooth-restoration complex hinge on reliable adhesion. This study aims to enhance the adhesion of lithium disilicate onlays by employing immediate dentin sealing (IDS) and evaluates its effective...

Background: Robotics in endodontics enhances precision, efficiency, and treatment success through AI, haptic feedback, and autonomous systems. Despite its potential, adoption is limited by cost, accessibility limitations, and training barriers. This scoping review explores applications, advancements, and comparative effectiveness of robotic-assiste...

Objective The success of root canal treatment and regenerative endodontics relies on thorough disinfection and dentin integrity preservation to ensure long-term tooth survival. This study evaluates the pH stability, material characteristics, microhardness and antimicrobial effects of an allicin-incorporated GO-AgNP hydrogel compared to conventional...

Premature loss of primary teeth is a common occurrence in pediatric dentistry and often necessitates the use of space maintainers to prevent complications. Traditional space maintainers, such as band and loop space maintainers (BLSM), have been widely used, but are fabricated using conventional methods. With advancements in technology, three-dimens...

Introduction: Tooth detection and numbering is a fundamental issue that has been the subject of research projects applying artificial intelligence in dental radiography evaluation. Objectives: The objectives of the current study were to build a deep learning model for detecting and numbering teeth, and to evaluate the model’s performance. Material...

Understanding the sealing ability of restorative materials to prevent microleakage and its consequent complications—such as secondary caries, postoperative sensitivity, and restoration failure—is imperative in clinical dentistry. This study aims to compare the microleakage performance of four restorative materials—bioactive composite resin (Activa...

Background Primary osteoblasts are essential for bone formation and regeneration, making them pivotal in dental applications, including periodontal regeneration, ridge augmentation, and implant osseointegration. Sourced from various tissues like alveolar bone, calvarial bone, mandibular and maxillary bones, long bones, and bone marrow-derived stem...

Background Shilajit is a pale-brown to blackish-brown fluid that varies in consistency and is released from rock layers in various mountain ranges across the world. For thousands of years, traditional medical systems in several nations have included shilajit in one form or another as a rejuvenator and adaptogen. Numerous medicinal qualities have be...

Globally, oral cancer ranks among the top ten cancers, with a higher prevalence in lower-income countries, where risk factors such as tobacco use, excessive alcohol consumption, and poor oral hygiene are widespread. Metastasis plays a critical role in cancer progression. miR-21 is a crucial regulator of cancer metastasis, profoundly influencing cel...

Objective The present research aims to examine the effectiveness of 980 nm Diode Laser and Twin Kleen irrigant individually in addition to the combo for removing the smear layer from tooth canals in single-rooted teeth. Materials and methods 60 single-rooted mandibular premolar teeth were chosen and inspected clinically and by radiography. Protape...

Understanding root canal morphology is essential for successful endodontic treatment. This study aimed to investigate morphological variations in root and canal systems of anterior and premolar teeth across different age groups and genders in a Saudi Arabian subpopulation using a novel classification system. A total of 3573 maxillary and mandibular...

Oral squamous cell carcinoma (OSCC) is the most prevalent type of malignant epithelial neoplasm that affects the oral cavity. It has been a significant health concern in many countries for a long time since it was usually treated with surgery, radiation, and/or chemotherapy. Drug resistance is the primary issue in patient populations and scientific...

Polydopamine (PD), inspired by the wet adhesion mechanism of mussel foot proteins, has emerged as a promising adhesive material with wide-ranging applications. This study aimed to compare the adhesive properties of PD and Glass Ionomer Cement (GIC) on enamel and dentin substrates, evaluating PD’s potential as an alternative adhesive in dental pract...

AIM- The objective of the systematic review is to evaluate the incidence of postoperative pain after single-visit and multiple-visit root canal therapy. METHODS- Published research indexed in PubMed or Scopus or Cochrane or DOAJ or Web of Science evaluating the frequency percentage of postoperative aching after one and several root canal therapy ap...

Background and objectives Aim of the current study was to assess the perception, preference, and practice of endodontists and restorative dentists at different locations around the world about dental magnification instruments. Materials and methods A multicenter, cross-sectional study was ethically approved from the local committee of bioethics. A...

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The present study investigated the involvement of human papillomavirus (HPV)16 and HPV18 in oropharyngeal malignancies in order to understand the oncogenic mechanisms, and to identify biomarkers for early detection and treatment targets. Given the rising incidence of HPV-associated cancer, particularly in India, this holds significance in elucidati...

This review explores the transformative potential of artificial intelligence (AI) in endodontics, focusing on its applications in enhancing diagnostic accuracy, treatment planning, and clinical outcomes. The primary objective is to synthesize current knowledge on AI technologies such as machine learning, deep learning, and neural networks and their...

Introduction This scoping review aimed to review the various challenges facing dental education. Dental education faces multiple institutional, student and faculty-based challenges. Institutional challenges include updating infrastructure resources, recruiting qualified faculty, and implementing administrative policies that enhance dental education...

Background Coronal microleakage, the passage of fluids and bacteria through the interface between the temporary restoration and the tooth structure, can potentially result in endodontic treatment failure. Purpose This study evaluated and compared the sealing efficacy of various temporary restorative materials utilized during endodontic procedures....

Background Dental composite resins are commonly used due to their excellent physical and mechanical properties. However, exposure to beverages like Coca‐Cola, Apple juice, and Black coffee can negatively impact these materials. This study examined the effects of these drinks on the surface microhardness and surface roughness of Nanohybrid, Giomer,...

Background A comprehensive understanding of the root form and canal anatomy is essential for successful endodontic treatment. This study aimed to evaluate the root canal anatomy of mandibular premolars in the Pakistani population using cone beam computed tomography (CBCT) and to classify the findings with the new classification proposed by Ahmed et...

Introduction India has committed to the Sustainable Development Goals (SDGs) 2030 principle of “Leave No One Behind”, which seeks to reduce disparities and vulnerabilities. The dearth of data on the oral health conditions of children with intellectual and developmental (IDD) disabilities in India is significant. Our systematic review intended to co...

Oral cancer, the most prevalent cancer worldwide, is far more likely to occur after the age of forty-five, according to the World Health Organization. Although many biomarkers have been discovered over the years using non-invasive saliva samples, biopsies, and human blood, these biomarkers have not been incorporated into standard clinical practice....

The occurrence of morphological deviations in root canal anatomy is challenging and can influence treatment outcomes. While mandibular second molars typically have 2 roots and 3 canals, a unique case emerged in a 23-year-old Indian male with a symptomatic permanent left mandibular second molar showing three distal, two mesial canals, and two roots....

Objectives This web-based survey, conducted across multiple countries, sought to explore the factors that impact the decision-making of clinicians when it comes to managing defective direct restorations. Methods A survey consisting of 14 questions was sent out to dentists in 21 countries through various online platforms. The survey consisted of tw...

Background Periodontal diseases, including gingivitis and periodontitis, are among the most prevalent oral health issues globally. They compromise the supportive structures of teeth and are influenced by both local and systemic factors. This study aimed to systematically assess the impact of systemic conditions on periodontal health in Malaysian po...

Background The aim of this systematic review and meta-analysis was to furnish evidence-based recommendations for the utilization of bioceramic-based and resin-based sealers in clinical endodontics, with a focus on reducing postoperative discomfort. Methods The investigation’s methodology was registered on the International Prospective Database of...

Background Oral cancer presents a significant global health challenge, driving ongoing research to enhance diagnostics and treatments. MicroRNAs, particularly miRNA99a, have emerged as key players in oral cancer's initiation, progression, and advanced development. However, their precise molecular mechanisms remain unclear. We analyze miRNA99a in mo...

Persistent antibiotic use in treating oral infections often leads to drug resistance in pathogenic bacteria, notably impacting conditions like periodontitis. Addressing this challenge, the study pioneers the use of carbon dots (CDs) synthesized from ginger rhizomes (Zingiber officinale) as a novel biocompatible material. CDs were synthesized via th...

Background: Artificial intelligence is an innovative technology that mimics human cognitive capacities and has gathered the world’s attention through its vast applications in various fields. Aim: This study is aimed at assessing the effects of ChatGPT 3.5 and ChatGPT 4 on the validity, reliability, and authenticity of standard assessment techniques...

Medical education is an ever-evolving realm, continuously striving for innovative methods to improve learning outcomes and nurture competent healthcare practitioners. Concept mapping has emerged as a valuable tool in this drive, aiding in the organization and synthesis of intricate information. This review delves into the infusion of Islamic teachi...

Introduction: Oral health education is essential for adolescents, yet traditional methods face challenges in engaging this demographic. This study evaluates the effectiveness of a multimedia-based dental education program among high school students. This study was carried out to assess the impact of a comprehensive multimedia-based dental education...

Background Apexification is a procedure that promotes apical closure by forming mineralized tissue in the apex region of a nonvital young permanent tooth. Calcium silicate-based cement like Mineral trioxide aggregate (MTA) and Biodentine are commonly employed as apical barriers to facilitate this process. Microleakage, defined as the leakage along...

India does not have a separate national program for public health aimed at screening newbornsfor genetic disorders. In present-day developing countries like India, the consideration of treatment through genetics is out of the question due to the unavailability of resources for such complicated treatments; the best approach that can be adopted is pr...

Objective To assess the clinical and radiographic success rates of regenerative pulpotomy compared to devitalising or preservative pulpotomy in treating vital pulp exposure in primary teeth. Methods Comprehensive search with PubMed/MEDLINE, Cochrane Library, Web of Science, Google Scholar and Open Grey databases was done and two reviewers extracted...

Background Pulp capping is a vital dental procedure used to preserve the vitality of teeth affected by deep caries lesions without irreversible pulpitis. The use of modern bioceramic materials has enhanced the predictability of vital pulp therapy (VPT). Aim This study aimed to assess the clinical success of Biodentine, modified NeoPutty mineral tr...

Background and Aim Dental caries is largely preventable, yet an important global health issue. Numerous systematic reviews have summarized the efficacy of artificial intelligence (AI) models for the diagnosis and detection of dental caries. Therefore, this umbrella review aimed to synthesize the results of systematic reviews on the application and...

Polyamide12 (PA12) has been used to fabricate flexible dentures for patients with prominent undercuts. It has a high moulding property, enabling it to take the shape of the canal without forming any voids, hence a suitable canal space restorative material. This study aims to investigate the chemicomechanical properties of PA12 composite reinforced...

Objectives The objective of this in vitro study was to evaluate the effects of different preparation designs on the mean colour change (ΔE*), marginal adaptation, fracture resistance, and fracture types of maxillary and mandibular premolar endocrowns (ECs). Methodology A total of 40 extracted maxillary and mandibular premolars were treated endodon...

Introduction Oral hygiene is paramount for maintaining optimal oral and physical health, especially among children who are particularly susceptible to dental caries and issues due to dietary habits and inadequate hygiene practices. This study aimed to evaluate the awareness and knowledge of oral health among public school children, analyse their or...

Background Understanding the root canal morphology is essential for the success of root canal treatment. Therefore, this study aimed to evaluate and analyze the root canal configuration of maxillary premolars using Cone Beam Computed Tomography in the Pakistani subpopulation. Method This cross-sectional study utilized CBCT scans from two distinct...

The use of fillers based on natural resources in composite materials represents a massive potential for biomedical applications. However, up to this date, the use of natural resources for materials reinforcement in dental field is still lacking. Thus, the suitability of using kenaf cellulose nanocrystals as a co-filler treated via silane hybridizat...

Medical and dental professionals should continue to adhere to preventive measures after COVID-19 vaccination due to their increased risk of exposure to the virus, particularly as new variants emerge that may heighten their risk perception and susceptibility. Therefore, this study aimed to explore the effects of COVID-19 vaccination on complacency t...

A precursor for effective root canal treatment (RCT) is a complete understanding of the internal anatomy of teeth. In this study, the authors aimed to classify the root canal morphology of anterior teeth in the Yemeni population and identify gender-based variations among them. In addition, the symmetry among adjacent quadrants was also evaluated. C...

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Carbon-based nanomaterials with a particle size of less than 10 nm are known as carbon dots (CDs). It is well recognized that these nanoparticles have a wide range of applications in the field of innovative drug delivery for conditions including cancer, infectious diseases, ocular illnesses, and brain disorders. CDs possess biocompatibility, eco-fr...

Iron nanoparticles comprise a significant class of inorganic nanoparticles, which discover applications in various zones by prudence of their few exciting properties. This study achieved the green synthesis of iron oxide nanoparticles (IONPs) by black cumin seed (Nigella sativa) extract, which acts as a reducing and capping agent. The iron nanopart...

Key Clinical Message The main objective of root canal therapy is to locate all the canals, cleaning, and shaping, and obturation to obtain fluid tight seal and to heal the periapical lesion if present. Abstract The proper cleaning, shaping, and disinfection of the pulp chambers, as well as the filling of the canals, are critical to the efficacy of...

Oral Squamous Cell Carcinoma (OSCC) management requires precise and effective strategies to assess the surgical margins. Integrating diagnostic markers into this evaluation presents a promising avenue for improving treatment approaches and improving patient outcomes. This review emphasizes the critical role of diagnostic markers in risk stratificat...

Background The invisibility of the transgender population within official records, combined with other socio-economic factors, impacts oral health status among transgender people. Hence, our systematic review and meta-analysis aim to generate a pooled estimate of the oral health status of the transgender community in India. Material and methods A...

Oral disorders can exert systemic ramifications beyond their localized effects on dental tissues, implicating a wide array of physiological conditions. The utilization of essential oils (EOs) for protection of oral health represents a longstanding practice. Consequently, in this investigation, essential oil derived from Nigella sativa seeds (NSEO)...

Objectives When dental practitioners encounter a defective restoration, they are faced with a crucial decision whether to repair or replace it. This study aims to explore international preferences for repair procedures and the clinical steps taken during the repair process. Method An 11-question survey was distributed to dentists across 21 countri...

Background In complex teeth like maxillary premolars, endodontic treatment success depends on a complete comprehension of root canal anatomy. The research on mandibular premolars’ root canal anatomy has been extensive and well-documented in existing literature. However, there appears to be a notable gap in available data concerning the root canal a...

Key Clinical Message Main objective of root canal therapy is to locate all the canals, cleaning and shaping, and obturation to obtain fluid tight seal. Failure to locate all canals can lead to the failure of root canal therapy. Abstract Variation of pulp aperture, among teeth with multiple roots, constitutes recurring issue during diagnosing and c...

The influence of behavioral science on various organizations has been experiencing remarkable growth worldwide. With the integration of recent technological advancements, behavioral science's impact has expanded into diverse fields such as finance and policy. The term "artificial intelligence" (AI) has become increasingly prevalent, but it is essen...

Background By increasing fluidity and conversion, pre-heated composites enhance adaptability and strength, while soft-start polymerization decreases internal stresses. Aim Over a period of a year, this split-mouth design, randomized controlled clinical trial (RCT) compared pre-heated composites with soft-start polymerization to conventional compos...

The present study explored the anticancer activity of a Chitosan-based nanogel incorporating thiocolchicoside and lauric acid (CTL) against oral cancer cell lines (KB-1). Cell viability, AO/EtBr dual staining and Cell cycle analysis were done to evaluate the impact of CTL nanogel on oral cancer cells. Real-time PCR was performed to analyze proapopt...

A BSTRACT Aim of the Study The aim of this in vitro study was to evaluate the effect of the resin infiltration technique and remineralization of induced enamel caries with fluoride solution on the color masking of white spot lesions and surface roughness. Materials and Methods A total of 45 sound teeth were used in this study. All the teeth were...

Advancements in understanding the malignant transformation pathways of oral submucous fibrosis: Implications for early detection and intervention Dear editor Oral Submucous Fibrosis (OSMF) is a chronic, potentially malignant disorder of the oral cavity characterized by fibrosis of the oral mucosa, leading to restricted mouth opening and an increase...

Introduction Root canal treatment procedures require a thorough understanding of root and canal anatomy. The purpose of this systematic review was to examine the morphological differences of teeth root and their canals assessed using cone-beam computed and micro-computed tomography in Saudi Arabian population. Methodology An electronic search was c...

Objectives This study aims to analyze the working time consumed during caries excavation and pain perception while using a novel Bioactive caries-detecting dye solution (BCD), an Air Polisher Prophy and a combination. Materials and methods Four groups (in each group, n = 20 permanent teeth) were selected from 60 people between 17 and 40 years of a...