Mohd Sayeed AkhtarM.J.P. Rohilkhand University · Department of Botany, Gandhi Faiz-e-Aam College, Shahjahanpur, India
Mohd Sayeed Akhtar
PhD (AMU, IN) Post Doc (BIB, SWISS & CBNU, S. KOREA), FRUPM (Malaysia)
About
186
Publications
226,124
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Introduction
Dr. Mohd Sayeed Akhtar is presently working as Professor (Assistant) in Gandhi Faiz-e-Aam College, Shahjahanpur, U.P., India. His current research is focused on plant microbes’ interactions and molecular biotechnology, bioremediation, nanofertilizers and nanobiotechnology. Dr. Akhtar has more than 20years of research and teaching experience and author and co-author of more than 150 research articles and book chapters. He has edited 30 books and also serving as editor/reviewers in reputed journal
Additional affiliations
October 2015 - present
Gandhi Faiz-E-Aam College Shahjahanpur, Uttar Pradesh, India
Position
- Professor (Assistant)
October 2015 - present
Gandhi Faiz-E-Aam College Shahjahanpur, Uttar Pradesh, India
Position
- Professor (Assistant)
October 2015 - July 2017
Education
August 2003 - December 2008
Aligarh Muslim University, Aligarh, India
Field of study
- Plant Pathology and Microbiology
Publications
Publications (186)
The yield and concentration of secondary metabolites (SMs) in plants can vary due to numerous challenges such as dynamic environmental conditions, moisture, soil quality, soil organic matter and plant genetics. To obtain a good yield of SMs novel elicitation approaches, such as the use of biotic and abiotic stressors, genetic modifications, and opt...
Background:
Coumarins, abundantly distributed in a plethora of biologically active compounds, serve as a fundamental motif in numerous natural products, drugs, and therapeutic leads. Despite their small size, they exhibit a diverse range of biological activities, intriguing researchers with their immense pharmacological potential.
Purpose:
This st...
Water is a precious commodity for plant growth and metabolism; however, its scarcity and saline sand conditions have a drastic effect on plant growth and development. The main objective of the current study was to understand how silicon (Si) application might help Black gram (Vigna mungo L.) against the negative impacts of salt stress and drought....
Flavonoids are secondary metabolites found in plants that have antioxidant properties and pigments that give fruits and vegetables their vivid hues. They improve heart health, fight cancer, and infections and reduce inflammation. They are vital in plant disease prevention and fungi–plant relationships. Plants develop secondary metabolites like flav...
Flavonoids are multi-functionary secondary metabolites which have anti-pathogenic properties. As flavonoids might play a potent role in plant defence, it becomes crucial to understand all aspects of the interaction between the plant and beneficial microbes, its pathogens, and the functionality of flavonoids that might influence them. Flavonoids are...
In nature, various changes occur in plant system due to biotic and abiotic agents. Changes occurring at physiological, molecular, and biochemical level in plants due to biotic factors mainly phytopathogens such as fungi, bacteria, nematodes, and viruses play an integral role in determining the overall health and functioning of plants. Over the year...
Nematodes and fungi are known to cause widespread destruction in major crops and hence create significant economic loss. Various parasitic mechanisms have evolved in different species, where the parasitism proteins have a big role to play. The majority of Avr genes in fungi are thought to produce effectors that promote virulence by inhibiting immun...
The escalating global concern over water pollution, predominantly propelled by industrial activities, underscores the urgency for effective environmental remediation strategies. Of particular, concern is the discharge of synthetic colorants into water bodies, a prevailing issue notably pervasive in textile industries. Azo dyes, ubiquitous in variou...
Nowadays, acute or chronic aflatoxicosis in humans has been a major source of concern. It is usually caused by eating foods contaminated with aflatoxins (AFs). As the environment changes and the causal pathogens multiply, the burden and prevalence of AFs on human exposure change as well. In clinical terms, the fungus impairs immunity and disrupts p...
The escalating cadmium influx from industrial activities and anthropogenic sources has raised serious environmental concerns due to its toxic effects on ecosystems and human health. This review delves into the intricate mechanisms underlying microbial resistance to cadmium, shedding light on the multifaceted interplay between microorganisms and thi...
An experiment was conducted to investigate the impact of cadmium (Cd) on growth, photosynthetic pigments (total chlorophyll and carotenoids), stress biomarkers (malondialdehyde, MDA; superoxide radicles; cell viability), mineral nutrients (sodium and phosphorus), leave protein content, defence (proline, superoxide dismutase, peroxidase, catalase),...
Chelating agents may decrease the extent of Ni phytoextraction by reducing plant growth and soil health due to Ni toxicity during enhanced phytoextraction. Contrarily, inducing acidity in the rhizosphere of Ni-accumulating plants with plant growth-promoting rhizobacteria (PGPR) having rhizosphere acidification ability can enhance Ni phytoextraction...
Polo-like kinase-1 (PLK-1) is an essential mitotic serine/threonine (Ser/Thr) kinase that belongs to the Polo-like kinase (PLK) family and is overexpressed in non-small cell lung cancer (NSCLC) via promotion of cell division. Therefore, PLK-1 may act as a promising target for the therapeutic cure of various cancers. Although a variety of anti-cance...
The aim of the study was to isolate and identify the most salt-tolerant endophytic bacteria from the mangrove plants ( Avicennia marina ) from the Red Sea Jeddah coastal region. In total, 21 endophytic bacteria were isolated from various parts of Avicennia marina cultured under various salt concentrations in laboratory conditions. Out of 21 endophy...
This study was designed to evaluate the pre-reproductive and reproductive responses of Linum usitatissimum L. (flax, linseed plant) to different levels of Pb in the soil. Flax seeds were sown in garden soil-filled earthen pots and treated with three different levels of lead as lead chloride (150, 450, and 750 mg Pb kg−1 soil) except control, and ea...
It is of interest to estimate the effects of foliar spray (ISA) on essential oil yield, chemical constituents, antioxidant, and antimicrobial activities of fennel (Foeniculum vulgare Mill).Fennel was treated with ISA solutions at 40 and 80 mg L-1 doses. Application of ISA significantly augmented antioxidant and antimicrobial activities in addition...
The aim of the study was to isolate and identify the most salt-tolerant endophytic bacteria from the mangrove plants (Avicennia marina) from the Red Sea Jeddah coastal region. In total, 21 endophytic bacteria were isolated from various parts of Avicennia marina cultured under various salt concentrations in laboratory conditions. Out of 21 endophyte...
O solo fornece um excelente nicho para os microrganismos rizospéricos e parece ser o ponto quente para as interações microbianas. Entre os microrganismos do solo Arbsucular mycorrhizal e outros microrganismos solubilizadores de fosfato podem promover o crescimento das plantas e também muito eficazes contra as doenças transmitidas pelo solo. Os fung...
Le sol offre une excellente niche pour les microorganismes rhizosperiques et semble être le point chaud des interactions microbiennes. Parmi les microorganismes du sol, les mycorhiziens arbsuculaires et d'autres microorganismes solubilisants au phosphate peuvent favoriser la croissance des plantes et sont également très efficaces contre les maladie...
Sequences are used to determine the accurate order of nucleotide bases in an individual. In this regard, the genomic and proteomic data sequences provide a clue on various biological processes, protein interactions, and disease pathways. The initiation and progression of various types of diseases are connected with biological processes, and the gen...
Genome analysis is gradually used to tackle the problems related to the diagnosis, profiling of microbiome, genotyping, mutation, and evolutionary studies. A number of challenges associated with genome analysis are related to the sequencing approaches and the adopted methodologies. Therefore, availability of genome sequences is directly influenced...
Soil salinity can cause havoc for agroecosystem as it is predicted about 50% of land will be saline in the next 50 years, but the coping techniques may reduce and even mitigate the adverse impact of soil salinity. Saline agriculture is already happening in the world, and hence it can be an opportunity for sustainability of agriculture. There are ma...
Soil salinity is the principal detrimental abiotic stress that globally impedes crop yield. It affects a wide range of biochemical, morphological, physiological, and molecular changes and is responsible for inducing ion toxicity, hormonal disturbance, water uptake, homeostasis disturbance, and oxidative stress. To evade this abiotic stress, many ge...
Twenty-first century is marked by many challenges regarding agro-ecosystems, such as environmental pollutions, scarcity of water, and increased salinization of soil and water. Population bomb (increasing human population) and reduction in land available for cultivation are two threats to agricultural sustainability. In this situation, demand for cu...
Soil salinity is one of the major causes of abiotic stress that limits crop productivity. It also affects nearly one-fifth of the worldwide cultivated lands. The negative effects of soil salinity in plants are related to the specific toxicity of ions, such as Na and Cl, as well as to the low osmotic potential of soil solution, which results in wate...
The environmental contamination has become a serious issue in recent times due to human engagements, such as application of pesticides, chemical preservatives, mining, coal combustion, etc. These anthropogenic activities have imposed escalated heavy metal concentrations in water, soil, and air. Specifically, heavy metal pollution of soils causes nu...
Water has a significant role on human civilizations by providing food and water along with plants grown on the banks or within the water bodies. Aquatic plants or semiaquatic plants are the group of plants that love to live in or near water bodies, and some of these plants are economically important due to their usage as food or medicinal plants. W...
Terpenoids are known to be a large family of secondary metabolites found ubiquitously in the plant kingdom and structurally composed of isoprenoid units. The diverse array of terpenoids has increased the interest in their commercial and pharmaceutical uses due to their antioxidative, anti-inflammation, and anticancer properties. Based on the struct...
A number of plant drugs are used in different medical conditions, mainly by the practitioners of traditional medicines. Some of the plants are used as a whole, but more often their parts including leaves, stems, roots, barks, bulbs, corms, seeds, and flowers are used to prepare different dosage forms intended to be used therapeutically. They contai...
Elaborates major classes of compounds like alkaloids, tannins, saponins, lignin, glycosides, and terpenoids, which are integral part of plant-microbe interactions for adapting to environmental irregularities
Describes the chemistry of bioactive plant secondary metabolites, their production and pharmacological properties, as well as biotechnologica...
Elaborates major classes of compounds like alkaloids, tannins, saponins, lignin, glycosides, and terpenoids, which are integral part of plant-microbe interactions for adapting to environmental irregularities
Describes the chemistry of bioactive plant secondary metabolites, their production and pharmacological properties, as well as biotechnologica...
Flavonoids are polyphenolic compounds of very important class of plant secondary metabolites having a broad spectrum of biological activities. Because of their antioxidative, anti-inflammatory, antimutagenic, and anticarcinogenic properties, flavonoids have become an indispensable component in nutraceuticals, pharmaceuticals, medicinal, and cosmeti...
Leptadenia pyrotechnica is an important medicinal plant of the family, Asclepiadaceae. It is usually found in the desert habitat, and generally used for the treatment of various diseases. The green parts of the plant species are used as fodder and vegetable, and are a very important source of protein, calcium, dietary fiber, phosphorus, vitamin C,...
Plant natural products have played an important role in the lives of human beings for their use as a source of food and medicine. The medicinal properties in plants typically result from the different combinations of these natural compounds known as phytochemicals. Generally, these phytochemicals are classified into primary and secondary compounds....
This study reports the biosynthesis of silver nanoparticles (AgNPs) using methanolic leaf extract of Pogostemon cablin Benth. (Patchouli) as a reducing agent, and their potent biological (antibacterial, antioxidant and anticancer) activities. The P. cablin extract when exposed to silver nitrate reduced silver ions to form crystalline AgNPs within 1...
Natural bioactive compounds have become an integral part of plant-microbe interactions geared toward adaptation to environmental changes. They regulate symbiosis, induce seed germination, and manifest allelopathic effects, i.e., they inhibit the growth of competing plant species in their vicinity. In addition, the use of natural bioactive compounds...
This book offers an overview of salt stress, which has a devastating effect on the yields of various agricultural crops around the globe. Excessive salts in soil reduce the availability of water, inhibit metabolic processes, and affect nutrient composition, osmotic balance, and hydraulic conductivity. Plants have developed a number of tolerance mec...
This book offers an overview of salt stress, which has a devastating effect on the yields of various agricultural crops around the globe. Excessive salts in soil reduce the availability of water, inhibit metabolic processes, and affect nutrient composition, osmotic balance, and hydraulic conductivity. Plants have developed a number of tolerance mec...
Cancer is one of the major causes of mortality in human population worldwide. The conventional drugs are known to be accompanied with severe side effects. Thus, the recent research is focused to find out the new chemotherapeutic agents of natural origin (plants derived) against cancer, which have the least side effects. In this regard, andrographol...
The survival rates of cancer patients are decreasing over the years which are possibly due to selection of poor conventional anti-cancer drugs. At present complementary and alternate medicines (CAM) are high on demand as they show few or rather zero side-effects. Metabolomic analysis is considered to be a complex as well as efficient bridge between...
Xylooligosaccharides (XOS), which are sugar oligomers that consist of 2–10 units of xylose, are non-digestible food ingredients produced mainly by the hydrolysis of xylan. The production of XOS from agricultural residues serves as a good source of products for the nutraceutical and pharmaceutical industries. XOS have a characteristic prebiotic effe...
An increased interest by consumers toward pharmacologically active plant-derived natural products as alternatives to synthetic drugs has increased the attention of global scientists. Among the various plant-derived natural products, essential oils have gained popularity because of its use in food, cosmetics, and pharmaceutical industries. Constitut...
Globally, cancer is a constant battle which severely affects the human population. The major limitations of the anticancer drugs are the deleterious side effects on the quality of life. Plants play a vital role in curing many diseases with minimal or no side effects. Phytocompounds derived from various medicinal plants serve as the best source of d...
Hedychium coronarium is a valuable medicinal plant and commonly known as butterfly ginger, belonging to family Zingiberaceae. It has enormous medicinal values in traditional system of medicine and also has the potential to be used in modern medicine. A number of bioactive compounds with different pharmaceutical properties including anticancer activ...
This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in...
Sida cordifolia Linn. belonging to the family, Malvaceae has been widely employed in traditional medications in many parts of the world including India, Brazil, and other Asian and African countries. The plant is extensively used in the Ayurvedic medicine preparation. There are more than 200 plant species within the genus Sida, which are distribute...
North-East India is known for the diversified range of medicinal plants which may extensively be used in the traditional medicinal practices against various ailments. Isolation of plant-derived bioactive compounds from these medicinal plants was well recognized in the past decades and some of them have been approved as medicines against diseases in...
Cancer is a multi-disease involving an abnormal growth of cells with the possibility of spreading or invading into other tissues of the body. Cancer harms the body by uncontrolled division of cells forming lumps or mass of tissue called tumor, which can be either benign or malignant type. The current practice of cancer treatments such as chemothera...
Cancer is one of the leading death cause of human population increasingly seen in recent times. Plants have been used for medicinal purposes since immemorial times. Though, several synthetic medicines are useful in treating cancer, they are inefficient and unsafe. However, plants have proved to be useful in cancer cure. Moreover, natural compounds...
Nanobiotechnology has emerged as a promising technology to develop new therapeutically active nanomaterials. The present study was aimed to biosynthesize AgNPs extracellularly using Aspergillus Niger JX556221 fungal extract and to evaluate their anticancer potential against colon cancer cell line, HT-29. UV-visible spectral characterization of the...
This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer type...
Genome is considered as the carrier of hereditary information and the operative system of an organism. The genomic data are in the form of sequentially arranged nucleotide base pairs. The data mining of genome resources is chiefly based on computational tools acknowledged as computational genome annotation. The computational genome annotation may b...
Hereditary information in an operative system is stored in genome. These genomic data are arranged in sequential form of nucleotide base pairs. In this regards, the computational genome annotation tools based on the structural and functional genome provides a wide array in analyzing the dynamicity and utility of genomic data resources. The aim of t...
Rapid utilization of nano-based products will inevitably release nanoparticles into the environment with unidentified consequences. Plants, being an integral part of ecosystem play a vital role in the incorporation of nanoparticles in food chain and thus, need to be critically assessed. The present study assesses the comparative phytotoxicity of na...
Experimental and epidemiological studies over the past few decades have provided ample evidences with regard to the association amid plant food consumption and decreased cancer risk. Many phytochemicals have proved their anticancer potential to be used as therapeutics against cancer. Among them garlic (Allium sativum) has been of much interest, mos...
Cancer is one of the leading causes of death in human beings. Though several synthetic medicines are used to treat cancer, they are largely inefficient and unsafe. In contrast, plants, which have been used for medicinal purposes since time immemorial, have proved to be useful in fighting cancer, with natural compounds from plants and their derivati...
A wide range of medicinal and aromatic plants (MAPs) have been explored for their essential oils in the past few decades. Essential oils are complex volatile compounds, synthesized naturally in different plant parts during the process of secondary metabolism. Essential oils have great potential in the field of biomedicine as they effectively destro...
Increased use of nitrogenous (N) fertilizers in agriculture has significantly altered the global N-cycle because they release nitrogenous gases of environmental concerns. The emission of nitrous oxide (N2O) contributes to the global greenhouse gas accumulation and the stratospheric ozone depletion. In addition, it causes nitrate leaching problem de...
Continuous supplementation of mineral nutrients and salicylic acid (SA) as foliar application could improve
efficacy in controlling basal stem rot (BSR) disease in oil palm seedling. It is revealed from the results that the highest disease severity index (58.3%) was recorded in T8 treatments at 9 months after inoculation. The best disease control w...
Phytoplasma is recognized as the serious constraints for the many economically ornamental plants all around the world. It may reduce the quality and yield of ornamental plants and is recognized internationally because of its unspecific symptoms, severe losses, and diverse epidemiology. The epidemics of these diseases have compelled the withdrawal o...
Microbial products have a long history of safe use and most of the microbial agents are compatible with other methods of pest control. A number of microbial biopesticides have been registered for field application on various vegetables, fruits, and other crops of agricultural, horticultural, and forest importance. During sporulation phase, Bacillus...
Truffles (Tuber spp.) belong to the fruiting bodies of certain hypogeous ascomycetes, which may grow in ectomycorrhizal symbioses with specified shrub and tree species. Some truffles, notably Tuber melanosporum and T. aestivum, form ‘burnt’ area, also known as ‘burn’ or ‘brûlé’ around their symbiotic
hosts. Increasingly focused interest has been ce...
Soil provides an excellent and diverse ecological niche for the rhizospheric microorganisms. Amongst the various rhizospheric microorganisms,mycorrhizal fungi, plant growth promoting bacterium and root nodule bacterium are of prime importance because they have the unique ability to interrelate with soil, host plant and also responsible for the asso...
Nanotechnology has been broadly used in the agricultural system since last few decades throughout the world, but still facing some challenge to be used as nano-fertilizers, because of its toxicity and hazardous effects on the environment as well as on the human health. Nevertheless, the nanomaterials could serve as a potential tool for the agricult...
The interactions between the plant, soil and microbes are complex in nature. Events may be antagonistic, mutualistic or synergistic, depending upon the types of microorganisms and their association with the plant and soil in question. Multi-trophic tactics can therefore be employed to nourish plants in various habitats and growth conditions. Unders...
Necrotrophic fungal pathogens cause major losses to fruit, vegetable, and cereal crops annually and the economic impact is more than that of diseases caused by biotrophic pathogens. These pathogens are devastating because they kill as they colonize through production of cell wall-degrading enzymes and phytotoxins, obtaining nutrients for growth and...
Plant growth-promoting rhizobacteria (PGPRs) are a group of naturally occurring beneficial soil bacteria that colonize with the plant root system and promote growth by triggering the production of growth-regulating substances and facilitate the plants in the uptake of essential nutrients from the surrounding environments. Similarly, arbuscular myco...
Biologically important plant-microbe interactions are mediated by a wide array of signal compounds rhizodeposited from both plant and microbial species. Root exudates are some of the potentially important low molecular weight compounds secreted from plant roots. They are involved in building a network of biointeractions through several physical, ch...
Phytoplasma is recognized as the serious constraints for the many economically ornamental plants all around the world. It may reduce the quality and yield of ornamental plants and is recognized internationally because of its unspecific symptoms, severe losses, and diverse epidemiology. The epidemics of these diseases have compelled the withdrawal o...
Research methodology is the backbone of any scientific communication. Based on the type of research (basic or advanced), the integration of apt methodology is highly desired for the wide acceptability among the scientific audiences. A standard scientific communications includes the insertion of different types of experimental variables and the pers...