Mohammadmahdi Sabahi

Mohammadmahdi Sabahi
Hamadan University of Medical Sciences | UMSHA · Medical school

Doctor of Medicine

About

46
Publications
2,303
Reads
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205
Citations
Citations since 2017
46 Research Items
205 Citations
2017201820192020202120222023020406080100
2017201820192020202120222023020406080100
2017201820192020202120222023020406080100
2017201820192020202120222023020406080100
Additional affiliations
March 2020 - April 2020
Medical University of Vienna
Position
  • Clerkship

Publications

Publications (46)
Article
Objective: Recurrent Cushing's disease (CD) is characterized by the reappearance of clinical and hormonal aspects of hypercortisolism that occur more than 6 months after an initial post-treatment remission. Methods: We performed a systematic review and meta-analysis to synthesize the evidence about remission and complication rates after transsph...
Article
Cushing's disease (CD) is associated with an increased risk of venous thromboembolic events. The purpose of this review is to discuss preventive strategies for post-operative thrombosis in CD patients and their impact on patient outcomes. A systematic review under PRISMA guidelines was conducted within PubMed, Embase, Web of Science, and Cochrane d...
Chapter
Head and neck cancers, as well as the therapies used to treat them, may result in considerable and long-term disabilities that decrease the patients’ quality of life. Thus, application of the most appropriate treatment for any patient who is diagnosed with these types of cancers is crucial and could improve the survival rate along with the quality...
Article
In the current study, we systematically review the literature regarding the management of optic pathway glioma (OPG). This review will analyze demographics, information regarding the type of treatment, radiological and clinical (visual) outcomes, and also complications. Article selection was performed by searching PubMed, Web of Science, and Cochra...
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Background: OPG accounts for 3-5% of childhood central nervous system (CNS) tumors and about 2% of pediatric glial lesions. Methods: Article selection was performed by searching PubMed, Web of Science, and Cochrane databases. Results: The pooled mortality rate was 0.12 (95%CI 0.09-0.14). Due to the unrepresentative data, improved and not chang...
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Methods: Sixty patients with a mean age of 68.60 ± 2.10 comprising 29 females (48.33%), who were admitted to an academic tertiary care facility within the first 12 hours poststroke symptoms onset or last known well (LKW), in case symptom onset time is not clear, were included in this study. AIS was confirmed based on a noncontrast head CT scan and...
Article
Background & Objective Researchers are currently trying to find new therapies with better symptomatic activity and fewer side effects to manage Parkinson’s disease (PD). Although the protective effect of pre-treatment by Gastrodin (Gst) on a PD model has been evaluated, in the current experimental study, we investigated the symptomatic therapeutic...
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Background: Circular RNAs (circRNAs) play pivotal roles in proliferation, apoptosis, migration, and invasion of renal cell carcinoma (RCC) cells. This study is aimed to systematically summarize the current evidence regarding the clinical implications of circRNAs in RCC patients. Methods: A systematic search in PubMed, Embase, and Web of Science...
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Background Cushing’s disease (CD) is among the most common etiologies of hypercortisolism. Magnetic resonance imaging (MRI) is often utilized in the diagnosis of CD, however, up to 64% of adrenocorticotropic hormone (ACTH)-producing pituitary microadenomas are undetectable on MRI. We report 15 cases of MRI negative CD who underwent surgical resecti...
Article
Background Microsurgical resection of intracranial cavernous malformations (CM) is regarded as the standard treatment, but in recent years, there has been a trend toward minimally invasive procedures like ablation of such lesions by using laser interstitial thermal therapy (LITT).MethodsA systematic search using keywords ‘laser interstitial thermal...
Article
Alzheimer’s disease (AD) is the most common cause of dementia globally. There is increasing evidence showing AD has no single pathogenic mechanism, and thus treatment approaches focusing only on one mechanism are unlikely to be meaningfully effective. With only one potentially disease modifying treatment approved, targeting amyloid-β (Aβ), AD is un...
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Cerebral mucormycosis (CM) is a life-threatening manifestation of mucormycosis, an angioinvasive fungal infection caused by Mucorales. We sought to systematically review all available case reports to describe epidemiologic features, clinical manifestations, predisposing factors, and diagnostic and treatment strategies of CM. A systematic search was...
Article
Objective In this systematic review and meta-analysis, we review the literature regarding Cushing's disease (CD) patients with negative or inconclusive MRI. Methods A quantitative systematic review was performed. Article selection was performed by searching MEDLINE (using PubMed), EMBASE, and Cochrane electronic bibliographic databases. Results 2...
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Background The history of intracranial hemorrhage (ICrH) is considered a contraindication for intravenous thrombolysis (IVT) among patients with acute ischemic stroke (AIS). Objective: This study aimed at comparing the safety of IVT among patients with and without a history of ICrH. Methods We performed a systematic review of the literature. Data...
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Background: Laser interstitial thermal therapy (LITT) has emerged as a treatment option for deep-seated primary and metastatic brain lesions; however, hardly any data exist regarding LITT for lesions of the posterior fossa. Methods: A quantitative systematic review was performed. Article selection was performed by searching MEDLINE (using PubMed...
Article
Leptin is a hormone that regulates appetite by acting on receptors in the hypothalamus, where it modifies food intake to maintain equilibrium with the body energy resources. Leptin and its receptors are widely distributed in the central nervous system, suggesting that they may give neuronal survival signals. The potential of leptin to decrease/incr...
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Objective: Postoperative inflammation and infections are common complications of spinal surgery and have similar symptoms. However, postoperative infection may lead to a poor outcome and must be differentiated from postoperative inflammation. The objective of this study is determine the changing pattern of postoperative ESR and WBC counts, and inv...
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Background Intracranial capillary hemangiomas (ICHs) have a natural history and behavior that is very different from intracranial cavernous malformations. The literature is not consistent as to the best management strategy for ICHs. Case description Our patient is a 40-day-old male infant who presented with progressive increase in head circumferen...
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The literature is rich with many studies reporting different treatment modalities and approaches for cystic craniopharyngioma (CC), including microsurgery, neuroendoscopic transventricular approach, endoscopic transnasal surgery, stereotactic drainage, and Ommaya reservoir insertion. The goals of this manuscript are to report the successful treatme...
Article
Background Pituitary adenomas (PAs) are among the most common brain tumors which characteristically become symptomatic due to the mass effect on surrounding structures and/or hormonal imbalances. This study describes 28 cases of PAs with an extrasellar invasive growth (EIG) at the early stage of tumor growth with normal sellar cavity size. Methods...
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The emergence of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) in late 2019 has been associated with a high rate of mortality and morbidity. It has been determined that the old population are not only at an increased risk for affliction with COVID-19 infection, but also atypical presentations, severe forms of the disease, and mortal...
Article
Craniopharyngioma (CPG) is a benign epithelial tumor that originates from Rathke’s pouch. Meningiomas (MNG) are neoplasms of meningothelial cell. The patient is a 42-year-old female who presented with left-sided temporal headaches and visual acuity impairment. Neurological examination revealed bilateral peripheral visual field defects. Imaging of t...
Article
Background Sylvian fissure arteriovenous malformations are rare but important vascular lesions, whose importance lies in both haemorrhage and seizure risk. Although surgery has been recommended as a treatment, the overall estimation of success has not been reported to render outcomes easier to understand in comparison to other treatment modalities....
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Along with emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in late 2019, a myriad of neurologic symptoms, associated with structural brain changes, were reported. In this paper, we provide evidence to critically discuss the claim that the survived patients could possibly be at increased risk for neurodegenerative...
Article
Parkinson's disease (PD), the most common movement disorder, comprises several pathophysiologic mechanisms including misfolded alpha‐synuclein aggregation, inflammation, mitochondrial dysfunction and synaptic loss. Nuclear Factor‐Kappa B (NF‐κB), as a key regulator of a myriad of cellular reactions, is shown to be involved in such mechanisms associ...
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Accumulation of misfolded tau, amyloid β (Aβ), and alpha-synuclein (α-syn) proteins is the fundamental contributor to many neurodegenerative diseases, namely Parkinson’s (PD) and AD. Such protein aggregations trigger activation of immune mechanisms in neuronal and glial, mainly M1-type microglia cells, leading to release of pro-inflammatory mediato...
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Introduction and Aim: Multiple Multiple sclerosis (MS) is a complex neurological condition might emerge as a result ofcomplex combination of genetic risk factors with environmental triggers, including oxidative stress. in this study we aimed to evaluate the effects of oral Crocin on oxidative stress in patients with MS. Materials and Methods: Adjun...
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Progressive loss in dopaminergic neurons (DA) of substantia nigra pars compacta (SNc) leads to Parkinson’s disease with a hypothesis of oxidative stress generation. The present study was conducted to determine the long-term efficacy of silymarin (SM) post-treatment on 6-OHDA–induced oxidative stress in the SNc of male rats. Male Wistar rats were re...
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Hemorrhagic vestibular schwannoma (HVS) consisting of acute intratumoral and subarachnoid hemorrhage presents with acute nausea, vomiting, facial numbness, headache, loss of consciousness, and significant functional impairment of the facial and vestibulocochlear nerves. The current case is of a 31-year-old man who was presented with acute left late...
Article
CAR T cell therapy is suggested as an effective method to treat hematological malignancies. However, high recurrence rates and in vivo toxicities have limited their widespread use. In order to reduce toxicity and improve tumor specificity, we propose a CAR T cell targeting glioblastoma multiforme utilizing the synNotch receptor pathway linked to a...
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Aim: The prevalence of human parvovirus B19 (B19V) and its association with other diseases in Iran are yet to be systematically assessed. This study aimed to evaluate the prevalence and disease association of B19V across Iran from 2000 to 2019. Methods: The literature search, based on different keywords in different databases, was performed. A tota...
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Hydatid cyst commonly affects liver followed by lung, but rarely affects may be found in almost any organ simultaneously. We present an unusual case of disseminated pulmonary hydatidosis and its imaging features before medical therapy. Diagnosis was confirmed by pathologic findings and positive response to antihelminthic drugs.
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Hydatid cyst commonly affects liver followed by lung, but rarely affects may be found in almost any organ simultaneously. We present an unusual case of disseminated pulmonary hydatidosis and its imaging features before medical therapy. Diagnosis was confirmed by pathologic findings and positive response to antihelminthic drugs.
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p> BACKGROUND The incidence of multiple pregnancies in industrialized countries due to the use of assisted reproductive techniques has increased over the past two decades. Multiple births are more dangerous than single pregnancies for mother and baby. This study evaluated the frequency of multiple pregnancies and its neonatal complications. METHO...
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Background and Objective: Vitamin D deficiency is considered one of the most common nutritional deficiencies associated with weakened immune system and increased likelihood of sepsis. The current study was conducted to investigate the association between serum vitamin D level and the severity and prognosis of ventilator associated pneumonia (VAP) i...
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Background and Aims: Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli are the most important bacteria responsible for hospital infections with multiple antibiotic resistance. Problems in the treatment of infections caused by resistant isolates have been the factor for the investigation of alternative drugs, including medicinal pla...
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BACKGROUND AND OBJECTIVE: Many non-motor symptoms of Parkinson's disease such as depression are associated with testosterone deficiency. On the other hand, the effect of testosterone therapy on the motor symptoms of Parkinson's disease is unknown. Therefore, the present study was conducted to evaluate the effect of testosterone on haloperidol-induc...

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