Mohammad Sabzezari

University of Tehran | UT ·  Research Department of Agricultural Biotechnology

Plants generate many secondary metabolites, so called phyto-metabolites, which can be used as toxins, dyes, drugs, and insecticides in bio-warfare plus bio-terrorism, industry, medicine, and agriculture, respectively. To 2013, the first generation metabolic engineering approaches like miRNA-based manipulation were widely adopted by researchers in b...

Inspired by nature, humankind has been able to attain significant achievements in the drug and food industries. Particularly, medicinal plants are a rich source of medicinal, cosmetic, sanitary, and aromatic substances. Genus Ferula from Apiaceae family is a plant genus that possesses over 170 species, which have been carefully documented with rega...

Paclitaxel is one of the strong plant-derived anti-cancer drugs that was first isolated from the Pacific yew. Despite many paclitaxel's clinical successes, the limited accessibility of paclitaxel for clinical trials is recognized as the most important challenge. Thus, researchers are continuously trying to find the innovative ways to meet the commu...

convergent technologies

Genetic engineering is the process of using recombinant DNA (rDNA) technology to alter the genetic makeup of an organism. Traditionally, humans have manipulated genomes indirectly by controlling breeding and selecting offspring with desired traits.

Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly inserts genetic material into a host genome, genome editing targets the insertions to site specific locations.

As an interdisciplinary field of science, bioinformatics combines biology, computer science, information engineering, mathematics and statistics to analyze and interpret biological data. Bioinformatics has been used for in silico analyses of biological queries using mathematical and statistical techniques.

Ispaghul (Plantago ovata Forsk.) as an important medicinal plant has obtained a remarkable reputation due to therapeutic applications of seed mucilage. To determine the effect of in vitro-induced polyploidy on various characteristics of P. ovata, the terminal bud of two true leaves seedlings were separately treated with colchicine [0.1, 0.3 and 0.5...

Plantago psylliumis is under development as the source of mucilage, but has not been entirely domesticated. Since mucilage content is low and variable in the medicinal plant, it is imperative to apply breeding approaches to accelerate the domestication process and improve the mucilage content in the seeds. One approach to achieve these purposes is...

Anyone who works with DNA is well aware of the dramatic changes that have taken place during the past few years in DNA sequencing methodology. To reflect these advances, in this new edition of Gene Cloning and DNA Analysis: An Introduction I have completely remodeled the chapter on DNA sequencing to give the new ‘next-generation’ methods equal prom...

Medicinal plants, are known to produce a wide range of plant secondary metabolites (PSMs) applied as insecticides, drugs, dyes and toxins in agriculture, medicine, industry and bio-warfare plus bio-terrorism, respectively. However, production of PSMs is usually in small quantities, so we need to find novel ways to increase both quantity and quality...

The world population is increasing at an alarming rate. While it has already crossed the seven billion line, it is expected to continue rising in the near future. To feed the teeming humanity in the new millennium, a huge responsibility lies on the shoulders of plant scientists to discover newer ways of enhancing crop production. Along with the inp...

Plant Genes, Genomes and Genetics provides a comprehensive treatment of all aspects of plant gene expression. Unique in explaining the subject from a plant perspective, it highlights the importance of key processes, many first discovered in plants, that impact how plants develop and interact with the environment. This text covers topics ranging fro...

Plants under abiotic stress are those suffering from drought, extreme temperatures, flood and other natural—but non-living—factors. Abiotic stress is responsible for reduced yields in several major crops, and climate change is focusing research in this area. To minimize cellular damage cause by such stresses, plants have evolved complex, well-coord...

Sugar beet (Beta vulgaris L.) is one of the two major products supplying sugar (sucroses) in the world. Rhizomania is one of the most destructive diseases of sugar beet world-wide. Holly is the major source of resistance to rhizomania. The objectives of this study were to identify the dominant homozygous genotypes resistant to rhizomania using ZN1...