Mohammad R Naghii

Baqiyatallah University of Medical Sciences | BMSU · Nutrition

Identifying the epidemiological characteristics of COVID-19 disease will help to make appropriate decisions and thus control the epidemic. Although many details, such as the source of the virus and its ability to spread between people remain unknown, an increasing number of cases show the signs of human-to-human transmission. The purpose of this re...

Identifying the epidemiological characteristics of COVID-19 disease will help to make appropriate decisions and thus control the epidemic. Although many details, such as the source of the virus and its ability to spread between people remain unknown, an increasing number of cases show the signs of human-to-human transmission. The purpose of this re...

Background Whole body vibration training (WBV) is a new training program, which is safe and effective. It can be followed by the public. However, data on the safety and efficacy of vibration on myocardial ischemia reperfusion (IR) injury are lacking. Objective To examine the effect of WBV on the tolerance of the myocardium to acute IR injury in an...

Kidney stone disease is a common form of renal disease. Antioxidants, such as vitamin E (Vit E) and boron, are substances that reduce the damage caused by oxidation. Adult male rats were divided into 5 groups (n=6). In group 1, rats received standard food and water for 28 days (control group); in group 2, standard rodent food and water with 0.75% e...

Prostate cancer is a complex, heterogeneous and multifactorial disease. The high prevalence of prostatitis could contribute to prostate carcinogenesis, which is the second most common cause of cancer-related death in males. Unfavorable metabolic profiles such as hormonal imbalances, oxidative stress and inflammation in prostate disorders are associ...

Prostate cancer is a complex, heterogeneous and multifactorial disease. The high prevalence of prostatitis could contribute to prostate carcinogenesis, which is the second most common cause of cancer-related death in males. Unfavorable metabolic profiles such as hormonal imbalances, oxidative stress and inflammation in prostate disorders are associ...

Introduction: Osteoarthritis is the most common joint disorder in modern societies. Elemental boron supplementation can support the influential effect of calcium, magnesium and vitamin D in the body. In that regard, the purpose of this study was to investigate the effect of boron on damaged knee joint cartilage in rats. Materials and Methods: In th...

Administration of natural antioxidants has been used to protect against nephrolithiasis. Urolithiasis was induced by ethylene glycol (EG) in Wistar rats. For 4 weeks, group 1 (control) was fed with a standard commercial diet. Group 2 received the same diet with 0.75% of EG. Group 3 received EG plus the diet and water added with antioxidant nutrient...

Objective: Stone disease is an increasingly common form of renal disease. Diet plays an important role in expression of the tendency to stone formation. Renal epithelial cell injury by reactive oxygen species is a pre-requisite step and the administration of natural antioxidants has been used to protect against nephrolithiasis. Considering the nut...

OBJECTIVE: The potential role for the gonadal steroids in the pathogenesis of urolithiasis, higher mean of plasma oxalate concentration and kidney calcium oxalate deposition influenced by androgens in men has been proposed. In this study, the serum levels of steroid hormones as a pathogenesis of this condition in male patients with active renal sto...

Renal epithelial cell injury by reactive oxygen species is a prerequisite step in the pathogenesis of urolithiasis, and there is increasing evidence that reactive oxygen species is produced and oxidative stress (OS) is developed during idiopathic calcium oxalate nephrolithiasis. It appears that the administration of natural antioxidants has been us...

The association between serum gonadal steroids and urolithiasis in males received only limited attention. Calcium oxalate urolithiasis is induced by administration of ethylene glycol in drinking water. It appears that the administration of natural antioxidants has been used to protect against nephrolithiasis in human and experimental animals. The p...

Unlabelled: Whole body vibration (WBV) has been regarded as an exercise training method and as a non-pharmacological supportive treatment option appearing to be efficient in chronic disease conditions, such as bone disorders and for cardio-respiratory fitness. Since, data on the safety and efficacy of vibration on oxidative stress parameters are l...

Objective: Stone disease is an increasingly common form of renal disease. Therapy to prevent stones rests in lowering supersaturation uses both diet and medication. Environmental factors, especially diet, play an important role in the expression of the tendency to stone formation. Effective treatment decreases stone recurrence and need to use proc...

Objective: The NAFLD is related to metabolic disorders and is negatively associated with kidney function. Renal stone disease (urolithiasis) is an increasing form of a common renal disease that is a multifactorial disorder influenced by both intrinsic and extrinsic, mainly environmental factors. The association between the fatty liver and renal ca...

Evidence indicates that optimal nutrition plays a role in bone formation and maintenance. Besides major components of mineralization such as calcium, phosphorus, and vitamin D, other nutrients like boron and fluoride have beneficial role, too. In this study, 34 male Wistar rats were divided into five groups: control diet, fluoride, fluoride + boron...

The consumption of fatty acids, nutrients, and regular physical activity, individually influence bone mechanical properties in rats. To investigate their effects in combination, male rats were divided into the seven groups: G1: regular food and drinking water; G2: same as Gr.1 + physical activity (Whole body vibration; WBV); G3: same as Gr.2 + Calc...

The effect of consumption of fatty acids and selected nutrients, along with regular physical activity, on cardiovascular risk factors in rats was investigated.Male rats were divided into the seven groups: Group 1: regular food and drinking water, Group 2: same as Group. 1 + physical activity (whole body vibration; WBV), Group 3: same as Group. 2 +...

Cardiovascular - coronary heart disease, causing heart attack and heart failure is a leading cause of disability and death worldwide. The most important risk factors for CVD are well-established and physical activity has long been considered the cornerstone of interventions and has shown extremely important in reducing the burden of this disease. T...

Whole body vibration (WBV) has been regarded as an exercise training method and as a non-pharmacological supportive treatment option appearing to be efficient for chronic disease conditions, such as bone disorders and cardio-respiratory fitness. Since, data on the safety and efficacy of vibration on plasma parameters are lacking, therefore, it was...

Cardiovascular/Coronary Heart Disease (CVD) is a leading cause of disability and death worldwide. The most important risk factors for CVD are well-established and are strongly influenced by lifestyle changes. Clearly, physical activity has been shown to be extremely important in reducing the burden of this disease. The aim of this case-control stud...

Boron possesses widespread properties in biochemistry and nutrition. Acute supplementation with 11.6 mg of boron resulted in a significant increase in plasma boron concentration. Given such a fast bioavailability, the objective was to determine whether acute (hourly or daily), and weekly supplementation could have any significant biological effects...

Urolithiasis is a multifactorial disorder influenced by both intrinsic and environmental factors. Among the studied factors, male gender with a three times higher incidence of urolitlithiasis than female gender is considered as a risk factor, but the influence of sex hormones on urinary stone formation remains undetermined. Since the association be...

In this study, the effects of cadmium toxicity and the protective effects of L-carnitine on spermatogenesis in Sprague-Dawley rat were evaluated. Animals were subdivided into five groups. Cadmium chloride (1-mg/kg body weight) was injected intraperitoneally during 16 days at intervals of 48 h between subsequent treatments. L-carnitine (500 mg/kg b....

Background. Recent evidence indicates that boron has a widespread role in biochemistry and nutrition and may have anti‐carcinogenic properties. It interacts with calcium, vitamin D and magnesium, which are all important in bone metabolism. Boron also increases steroid hormone concentrations in animals and humans and hints at a role in the preventio...

Iron deficiency, anemia, is the most prevalent nutritional problem in the world today. The objective of this study was to consider the effectiveness of consumption of iron fortified ready-to-eat cereal and pumpkin seed kernels as two sources of dietary iron on status of iron nutrition and response of hematological characteristics of women at reprod...

Objective: The aims of this study were to determine the prevalence of risk factors for coronary heart disease and the risk of coronary heart disease events before and after the introduction of healthy lifestyle changes among a group of medical university staff. Methods and results: A total of 98 medical university staff participated in this befo...

Weight or fat reduction and maintenance among military personnel and attainment of desired body composition and physical appearance are considered important. A high level of body fat has been shown to have an adverse effect on performance in a number of military activities. The effect of rapid weight loss on performance appears to depend on the met...

Iron deficiency anemia is caused by decreased production of red blood cells (RBCs) and is characterized by a reduction in either the hematocrit (Ht) or the concentration of hemoglobin (Hb). It is detected by blood iron status measures that are below population reference standards and also below the "usual or normal" levels for an individual. In som...

The objective of this study was to consider the effects of boron (B) and calcium (Ca) supplementation on mechanical properties of bone tissues and mineral content of the selected bones in rats. Adult male Sprague Dawley rats underwent three different treatments with boron and calcium in their drinking water, while taking diet ad libitum for 4 weeks...

Un terremoto de gran magnitud en una zona urbana es uno de los peores desastres naturales que pueden ocurrir en ciertas partes del mundo. La mayor parte de las medidas aplicables para mitigar los traumatismos tienen que implantarse antes de que el desastre ocurra. Los investigadores han identificado algunos factores de riesgo importantes en relació...

Sulfur Mustard (SM) is a potent alkylating agent with electrophilic property which has been used as a chemical warfare agent in at least 12 conflicts. It has reemerged as a major threat in recent years. Medical attention is primarily concerned with its action on the skin, eyes, and respiratory tract which may be complicated by damage to ophthalmic,...

Sulfur Mustard (SM) is a potent alkylating agent with electrophilic property which has been used as a chemical warfare agent in at least 12 conflicts. It has reemerged as a major threat in recent years. Medical attention is primarily concerned with its action on the skin, eyes, and respiratory tract which may be complicated by damage to ophthalmic,...

A simple clinical blood test, which measures the total antioxidant status of Low Density Lipoprotein (LDL) and therefore its vulnerability to oxidative stress is suggested, and as a first stage this was tried on a small sample of eight healthy adult males. The body's natural defence and repair systems try to handle all free radicals, but these syst...

Intake of food and drink during exercise can be effective in enhancing performance, in so far as it prevents or ameliorates exercise-induced changes to body homeostasis. Loss of body fluids containing water and electrolytes during exercise is mostly by sweating. Sweat rates during a sporting event or activity will vary according to a number of fact...

Ergogenic substances and synthetic steroids have a wide spread use, particularly among nonprofessional athletes. To avoid the side-effect of drug abuse, it is suggested that the key to success is a proper athletic nutrition. It is a balanced intake of nutritional wholesome foods that contain a proper blend of essential nutrients. Knowledge of human...

We have undertaken studies in humans and animals that aimed to obtain further information about the intake and excretion of boron (B) as well as its effects on markers of coronary heart disease. In humans, we have shown that the intake of B is 2.2 mg/d; its urinary excretion is 1.9 mg/d, and there appears to be little intraindividual variation. Sup...

Boron (B) is an essential trace element for plants and its interrelationship with mineral and bone metabolism and endocrine function in humans has been proposed. Relatively little is known about the occurrence of B in the food chain and hence a biomarker which reflects its intake is required. Two studies were carried out to quantify the urinary B c...

Recent studies have indicated that dietary boron can affect the concentration of steroid hormones in vivo. It has been suggested that the interaction between boron and steroid hormone metabolism is mediated by the hydroxylation process that steroids need to become biologically active. The increase in the concentration of some steroid hormones may i...

Boron is an essential micronutrient for higher plants. The results of studies in animals and humans have suggested a potential role for boron as a modulator of the steroid hormone pathway. As part of a study to obtain baseline information on boron in humans, the boron content of selected foods (66 items) consumed in Australia was determined. Mean v...

Boron has been shown to increase the concentration of oestrogen and testosterone in plasma. The aim of this study was to investigate further the effect of boron by determining the response to three levels of boron intake during an experimental period of 6 weeks. The concentration of plasma testosterone and its production in the testes were determin...

Flavonoids are potent inhibitors of the oxidative modification of low-density lipoprotein (LDL), and foods containing these compounds have been shown to be negatively associated with coronary heart disease (CHD). Flavonoids reduce the formation of free radicals and protect or regenerate other antioxidants; or alternatively, they chelate divalent me...

A large number of responses to dietary boron occur when the boron content of the diet is manipulated. Numerous studies suggest that boron interacts with other nutrients and plays a regulatory role in the metabolism of minerals, such as calcium, and subsequently bone metabolism. Although the mechanism of action has not been defined, it may be mediat...