Mohammad Razuanul Hoque

University of Chittagong · Department of Biochemistry and Molecular Biology

Cervical cancer is the fourth most common cancer among women worldwide, with approximately 70% of cases involving infection with human papillomavirus (HPV) genotypes 16 and 18. According to International Agency for Research on Cancer, more than 50 million Bangladeshi women are at risk of developing cervical cancer, and 17 686 new cases and 10 362 d...

Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third most common cause of cancer mortality worldwide. Infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV) is the most predominant cause of HCC. Concerns arise for the presence of additional risk factors, as there is still a large proportion of patients without...

With the progress of optogenetics, the activities of genetically identified neurons can be optically silenced to determine whether the neurons in question are necessary for the network performance of the behavioral expression. This logical induction is expected to be improved by the application of the Na⁺ pump rhodopsins (NaRs), which hyperpolarize...

Ion-transport activity of I1K6NaR. (a-c) Light-induced pH changes upon light-illumination (>500 nm, indicated by yellow lines) on the E. coli cells expressing I1K6NaR in 100 mM NaCl (a), 100 mM Na2SO4 (b) and 100 mM KCl (c) without (blue lines) and with CCCP (green lines). (PDF)

Background Migraine is one of the most common neurologic disorders occurring in 15% Europeans and approximately 18.5% of the world population. It is the most frequently observed (up to 40%) ‘non-criteria’ neurologic manifestations in patients with antiphospholipid syndrome (APS) where at least one of the antiphospholipid antibodies (aPLs) [lupus an...

The five glutamate (E) residues of transmembrane (TM)-2 of channelrhodopsin (CrChR)-2 are conserved among several members of the ChR family. A point mutation of one of them, E97 to a nonpolar alanine (E97A) reduced the photocurrent amplitude without influencing other photocurrent properties. The charge at this position is also the determinant of Gd...

Non-invasive remote control technologies designed to manipulate neural functions have been long-awaited for the comprehensive and quantitative understanding of neuronal network in the brain as well as for the therapy of neurological disorders. Recently, it has become possible for the neuronal activity to be optically manipulated using biological ph...

Krokinobacter eikastus rhodopsin 2 (KR2) is the first light-driven Na(+) pump discovered, and is viewed as a potential next-generation optogenetics tool. Since the positively charged Schiff base proton, located within the ion-conducting pathway of all light-driven ion pumps, was thought to prohibit the transport of a non-proton cation, the discover...

Curcuma casiea (Black Turmeric) is a kind of turmeric with bluish-black rhizome, famous for its unique medicinal properties. It is a perennial herb, belonging to Zingiberaceae (Ginger) family, native to North-East and Central India. The leaves have a deep violet-red patch which runs through the length of the lamina. Usually, the upper side of the l...

Context: Racial and sex differences are documented globally regarding patterns of serum lipids among diabetic patients. Differences of lipid profile of normal and diabetic subjects of the different ethnic groups of Bangladesh may differ. Objectives: To find out if there were any differences in the serum lipid and lipoprotein levels in the type 2 di...

Our current study deals with 62 plants of ethno botanical importance that are used by the village doctors known as Baddya of Chittagong Hill Tracts (CHT). They have been using these plants by heredity for many diseases for about 600 years. According to them the effectiveness of medicinal plants obtained from CHT area are better than those obtained...

This study was conducted to create a nutritional data for Laminaria, Sargassum and Fucus sp.in order to popularize their consumption and utilization in Bangladesh. These three brown seaweeds were collected from November, 2004 to April, 2005 from St. Martin’s Island. The maximum and the minimum percentage of protein were noted to be 6.25 and 2.55...