Mohammad Daneshzand

Mohammad Daneshzand
Harvard Medical School | HMS · Athinoula A. Martinos Center for Biomedical Imaging

PhD in Computer science and engineering

About

25
Publications
5,405
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117
Citations

Publications

Publications (25)
Conference Paper
Transcranial Magnetic Stimulation (TMS) is a non-invasive method for safe and painless activation of cortical neurons. On-line visualization of the induced Electric field (E-field) has the potential to improve quantitative targeting and dosing of stimulation, however present commercially available systems are limited by simplified approximations of...
Article
Full-text available
The Transcranial Magnetic Stimulation (TMS) inverse problem (TMS-IP) investigated in this study aims to focus the TMS induced electric field close to a specified target point defined on the gray matter interface in the M1HAND area while otherwise minimizing it. The goal of the study is to numerically evaluate the degree of improvement of the TMS-IP...
Conference Paper
Full-text available
To enable concurrent non-invasive stimulation (TMS) and whole-head multimodal imaging (EEG-fMRI), we propose to apply Bexible RF coil technology to build a Erst-of-its-kind TMS compatible integrated multimodal imaging array, the “RF- EEG cap”. The proposed system allows unrestricted positioning of the TMS coil across the entire scalp. We built a 2-...
Article
Full-text available
Background: TMS neuronavigation with on-line display of the induced electric field (E-field) has the potential to improve quantitative targeting and dosing of stimulation, but present commercially available solutions are limited by simplified approximations. Objective: Developing a near real-time method for accurate approximation of TMS induced...
Article
Full-text available
Purpose: Multichannel Transcranial Magnetic Stimulation (mTMS) arrays enable multiple sites to be stimulated simultaneously or sequentially under electronic control without moving the system's stimulation coils. Here, we build and characterize the performance of a novel modular 3-axis TMS coil that can be utilized as a unit element in large-scale...
Article
Objective: To present and disseminate our transcranial magnetic stimulation (TMS) modeling software toolkit, including several new algorithmic developments, and to apply this software to realistic TMS modeling scenarios given a high-resolution model of the human head including cortical geometry and an accurate coil model. Approach: The recently...
Preprint
A particular yet computationally successful solution of an inverse transcranial magnetic stimulation (TMS) problem is reported. The goal has been focusing the normal unsigned electric field at the inner cortical surface and its vicinity (the D wave activation site) given a unique high-resolution gyral pattern of a subject and a precise coil model....
Article
Full-text available
The hyperkinetic symptoms of Parkinson’s Disease (PD) are associated with the ensembles of interacting oscillators that cause excess or abnormal synchronous behavior within the Basal Ganglia (BG) circuitry. Delayed feedback stimulation is a closed loop technique shown to suppress this synchronous oscillatory activity. Deep Brain Stimulation (DBS) v...
Data
Neuronal dynamics, firing patterns, LFP recordings, PSD and EC data. (PDF)
Conference Paper
Neural oscillations within the Basal Ganglia (BG) circuitry are associated with Parkinson’s Disease (PD) and are observable through the Local Field Potential (LFP) of the Subthalamic Nucleus (STN) or Globus Pallidus externa (GPe) neurons. LFP amplitude modulation in a delayed feedback protocol for Deep Brain Stimulation (DBS) is shown to destabiliz...
Article
Full-text available
To investigate how different types of neurons can produce well-known spiking patterns, a new computationally efficient model is proposed in this paper. This model can help realize the neuronal interconnection issues. The model can demonstrate various neuronal behaviors observed in vivo through simple parameter modification. The behaviors include to...
Article
Full-text available
Deep brain stimulation (DBS) has compelling results in the desynchronization of the basal ganglia neuronal activities and thus, is used in treating the motor symptoms of Parkinson's disease (PD). Accurate definition of DBS waveform parameters could avert tissue or electrode damage, increase the neuronal activity and reduce energy cost which will pr...
Conference Paper
This work represents the design and verification of three different finite impulse response (FIR) filter implementations for removing the noise of electrocardiogram (ECG) signals. Generally, ECG signals may be contaminated with different noise sources such as body movement and respiration, electromyography (EMG) interference, power line interferenc...
Conference Paper
Full-text available
Most applications dealing with wireless sensor networks need a strategy to reduce the energy usage. Each node in a wireless sensor network has a certain amount of energy, in which in some applications is crucial for a system to have stable nodes with the ability of working properly. One of the recent algorithms to have an energy efficient topology...
Article
Full-text available
In all mammalian brain billions of neurons exist and these neurons are working together through synapses and spike responses. Through numerous models presented to describe neuronal response and how the membrane potential would vary due to different tasks, still a big question stand still in the field of neuroscience. Why a neuron can produce differ...
Conference Paper
Full-text available
To investigate how different types of neurons in brain can produce well known spiking patterns, a new computationally efficient model is proposed in this poster. The model can demonstrate various neuronal behavior observed in vivo such as abnormal pattern of subthalamic nucleus (STN) in Parkinson's disease. The irregular and arrhythmic behavior of...
Conference Paper
Full-text available
A Superposed Quantum Model of Brain Spiking Neurons in all mammalian brain billions of neurons exist and these neurons are working together through synapses and spike responses. A big question stand still in the field of neuroscience. Why a neuron can produce different types of spikes under same conditions? We showed that unknown and random behavio...
Conference Paper
Full-text available
In this work, an efficient digital system is designed using hardware to filter the Electrocardiogram (ECG) signal and to detect the QRS complex (beats). The system implementation has been done by using a Field Programmable Gate Array (FPGA). In the first phase of the hardware system implementation, Finite Impulse Response (FIR) filters are designed...
Conference Paper
Full-text available
In medical diagnosis and therapy, finding an appropriate method to evaluate the effect of various drugs is crucial. There are several ways to qualify a drug for a specific disease and one way is through medical image analysis. This process varies with the tissues we want to analyze and the imaging technique that is employed. For hydrous tissue...
Conference Paper
Full-text available
Coronary artery heart disease is one of the main reasons of death in under development countries such as Iran. Based on vagueness in data and uncertainty in decision making finding an optimal way for diagnosis would be helpful. The main goal of this article is to change the linguistic terms which doctors use for representing coronary heart disease...

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Projects (3)
Project
Design of effective stimulus pulses for desynchronization of neural population in thalamus and basal ganglia.