Mohammad Asghari Jafarabadi

Tabriz University of Medical Sciences | TBZMED · Department of Statistics and Epidemiology

Studies investigating the nuclear factor erythroid 2-related factor 2 (Nrf2) expression levels in the respiratory system of healthy subjects are scarce. Moreover, separate studies on the health-related outcomes of air pollution for each sex are limited. The current panel study investigated sex-specific Nrf2 expression levels and related oxidative s...

Background Diabetes management in hemodialysis patients with end-stage renal disease needs precision to avoid complications. The study aimed to investigate the effect of ginger supplementation on prooxidant-antioxidant balance, glycemic management, and renal function in diabetic hemodialysis patients. Trial design and methods Forty-four patients w...

Purpose In 2019, in Australia, there were 500,000 people aged 85 and over. Traditionally, clinicians have adopted the view that surgery is not desirable in this cohort due to increasing perioperative risk, perceived minimal clinical benefit, and shortened life expectancy. This cohort study is aimed at investigating postoperative outcomes from elect...

Background: The quality of sleep has different physical and psychological consequences, and can affect students' academic achievement. Objectives: This study aimed to explore factors associated with sleep quality in university students using panel regression. Methods: This study was conducted based on the data from a longitudinal study, namely the...

Background: Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to meet targets set for ending the epidemic by the Joint United Nations Programme on HIV/AIDS (UNAIDS) and the United Nations Sustain...

Background: Using both hands is regularly needed for force/torque exertions in many activities, especially when using hand tools. Objective: To investigate the effects of tool grip span, workpiece orientation, moving direction, and working height on two-handed wrist U/R deviation torque strength, usability, comfort, and discomfort while using lo...

Introduction This study aimed to collect and summarize test data and conduct a meta-analysis, with respect to the Multitarget Stool DNA test sensitivity and specificity, compared to colonoscopy. Material and methods All manuscripts were screened for eligibility according to inclusion criteria. Participants were a normal population at an average ri...

Background Prevention of road traffic injuries (RTIs) as a critical public health issue requires coordinated efforts. We aimed to model influential factors related to traffic safety. Methods In this cross-sectional study, the information from 384,614 observations recorded in Integrated Road Traffic Injury Registry System (IRTIRS) in a one-year per...

Introduction Atherosclerotic cardiovascular disease (ASCVD) is the first leading cause of mortality globally. To identify the individual risk factors of ASCVD utilizing the machine learning (ML) approaches.Materials & methodsThis cohort-based cross-sectional study was conducted on data of 500 participants with ASCVD among Tabriz University Medical...

Background Prediction of preterm birth is still a challenge due to its multiple etiologies. This prospective cohort study aimed to determine the technology-free predictors of preterm birth in singleton women with threatened preterm labor. Methods This prospective cohort study was performed on 371 singleton women with gestational age of 23+ 6 to 36...

Background : There is a great need for a valid hearing loss measurement tool in the Persian language to help identify hearing handicaps and potential communicational difficulties among Persian-speaking older adults. The present study aimed to validate and adapt the original English version of the Hearing Handicap Inventory for the Elderly (HHIE) in...

This study aimed to examine the validity and reliability of a semi-quantitative food frequency questionnaire (FFQ) designed to estimate dietary vitamin D and Calcium (Ca) intakes in a sample of Iranian childbearing age women. An 87-item FFQ was developed and 84 healthy childbearing age women completed it. FFQ was validated by comparing its results...

Objective This study aimed at utilizing a Bayesian approach semi-competing risks technique to model the underlying predictors of early recurrence and postoperative Death in patients with colorectal cancer (CRC). Methods In this prospective cohort study, 284 patients with colorectal cancer, who underwent surgery, referred to Imam Khomeini clinic in...

Background. The concept of age-friendly cities has been introduced by the World Health Organization in order to pay more attention to the elderly. In Iran, this issue is more important due to demographic changes and age conditions. Therefore, this study was conducted to investigate the views of the elderly in Tabriz city of Iran about some indicato...

Background Onchocerciasis is a disease caused by infection with Onchocerca volvulus, which is transmitted to humans via the bite of several species of black fly, and is responsible for permanent blindness or vision loss, as well as severe skin disease. Predominantly endemic in parts of Africa and Yemen, preventive chemotherapy with mass drug admini...

The use of both hands is often required for force/torque exertions, particularly when using hand tools. This study investigated the effects of handle diameter (3-5 cm), between-handle distance (0.5–1.5 shoulder span (SS), workpiece orientation (horizontal/frontal), working height (shoulder/elbow/knuckle), and exertion direction (clockwise/counter-c...

BACKGROUND Perceived control and support can contribute to a positive childbirth experience. However, most studies have not differentiated between perceived internal and external control. OBJECTIVE The present study aimed to assess primiparous women’s perceived internal control, external control, and support, including family and professional supp...

Major depressive disorder (MDD) is regarded as an inflammatory disorder. Gut microbiota dysbiosis, observed in both MDD and obesity, leads to endotoxemia and inflammatory status, eventually exacerbating depressive symptoms. Manipulation of gut microbiota by prebiotics might help alleviate depression. The present study aimed to investigate the effec...

Background and aim Marriage is one of the most important phenomena in human life. The survival of the marriage and the impact of various competing factors on the survival is of high importance. This study aimed at utilizing competing risks survival analysis to investigate the marriage survival of new couples in Tabriz. Methods In this longitudinal...

Unlabelled: Due to the need for face-to-face administration of many cognitive screening tests, it is not always feasible to screen large-scale samples. Objective: This study aimed to assess the discriminant validity of the Persian version of Telephone Interview for Cognitive Status (P-TICS-m) and Mini-Mental State Examination in the middle-aged...

Background Prevention of Road traffic deaths as a critical public health issue requires coordinated efforts. We aimed to determine influential factors related to traffic safety in Iran as a low-income country (LIC). Methods In this study with a cross-sectional design, the information of 384,614 road traffic crashes recorded in Integrated Road Traff...

Objective Sleep disorders are common during prenatal and postpartum periods which can be associated with physical and psychological maternal and neonatal outcomes. The aim of this study was to determine the psychometric properties of the Persian version of Postpartum Sleep Quality Scale.Methods In this study, 280 women who had given birth two to fo...

Background Due to limited capability to function in post-injury daily life injury, survivors need to be reliably assessed without need to commute more than necessary. The key action is to determine the level of functioning difficulties. Having the opportunity of conducting a national post-crash traffic safety and health cohort study, we aimed to tr...

Aim In the presence of competing risks, patients with human immunodeficiency viruses (HIV) experience death by various causes, including co-infection with acquired immune deficiency syndrome (AIDS) with tuberculosis (TB), AIDS, and other causes in the follow-up. This study aimed to model the survival in patients with HIV in the presence of these co...

Objectives: To assess the relationship between serum lipid profile and some cardiovascular risk factors. Methodology: This cross-sectional study consisted of pregnant and non-lactating women aged 30-55 years, selected by convenience sampling method from who referring health center in Tabriz, Iran from April to May 2017. Anthropometric measurements,...

Introduction Cardiovascular disease (CVD) is the most important cause of death worldwide. The incidence of CVD is increasing all over the world, particularly in developing countries [1]. There are 17.5 million deaths annually due to CVD in the world. It has been estimated that 50% of all deaths per year are attributed to CVD in Iran [2], and these...

Oxidative stress plays a fundamental role in the development and progression of nonalcoholic fatty liver disease (NAFLD). This study aimed to investigate the effects of a calorie-restricted (CR) diet on oxidative/anti-oxidative status in patients with NAFLD and the potential mediating role of fibroblast growth factor 21 (FGF-21) in this regard. Thi...

Introduction: Isolation and self-quarantine can expose individuals, particularly older people, to cognitive and physical decline. Due to a reduction in their musculoskeletal and neural flexibility, older adults are more likely to be affected by quarantine limitations. This study aimed to investigate the effect of self-quarantine on cognitive and...

Background Prediction of preterm birth is still a challenge due to its multiple pathologies. This prospective cohort study aimed to determine the technology-free predictors of preterm birth in singleton women with threatened preterm labor. Methods This prospective cohort study was performed on 371 singleton women with gestational age of 23+ 6 to 3...

We aimed to develop and test the psychometric properties of the Perceived Barriers of Mammography Scale (PBMS-23). Based on a mixed method design researchers generated item pool through qualitative data and literature review and next, 500 women ages 40 to 69 years completed the questionnaire. Based on exploratory and confirmatory Factor Analysis, 2...

This study aimed to develop and validate a labor induction nomogram for nulliparous and multiparous women who were 38 weeks pregnant or more and had their labor induced by an unfavorable cervix. This prospective study was conducted on 300 individuals (200 for nomogram development and 100 for nomogram validation). Height, body mass index at delivery...

Arsenic concentrations in different environmental media (water, soil/sediment, food) in Iran from studies performed 2008-2019 were analyzed, and health risk assessment was conducted to depict the arsenic pollution situation at the national scale. Seventy-one studies comprising 5,007 samples were included in the meta-analysis. The weighted concentra...

The aim of this study was to investigate the effects of mental workload (MWL) and time of day on cognitive performance and electroencephalographic (EEG) parameters of air traffic controllers. EEG signals recorded while 20 professional air traffic controllers performed cognitive tasks [A-X Continuous Performance Test (AX-CPT) and 3-back working memo...

In this prospective cohort study, we aimed to investigate external validity of the Allouche’s nomogram to predict preterm birth in symptomatic women in Iran. We employed six variables of cervical length, uterine contractions, rupture of membranes, vaginal bleeding, gestational age, and multiple pregnancy to draw the nomograms. These variables were...

Background: Today, cardiovascular disease (CVD) is the leading cause of mortality in both sexes. There are several risk factors for heart diseases; some controllable, others not. However, socioeconomic, technological, and environmental factors can impact CVD as well as exclusive risk factors. Accurate identification and assessment of these factors...

Background: Due to more limited capability to function in daily life post injury, survivors need to be reliably assessed without extra commute. The key action is to determine the level of functioning difficulties. Having the opportunity of conducting a national post-crash traffic safety and health cohort study, we aimed to translate and assess the...

Background Better evaluation of existing health programmes, appropriate policy making against emerging health threats, and reducing inequalities in Iran rely on a comprehensive national and subnational breakdown of the burden of diseases, injuries, and risk factors. Methods In this systematic analysis, we present the national and subnational estim...

Background Colorectal cancer is the third leading cause of cancer deaths worldwide. Given the recent increasing trends in colorectal cancer incidence globally, up-to-date information on the colorectal cancer burden could guide screening, early detection, and treatment strategies, and help effectively allocate resources. We examined the temporal pat...

Nonalcoholic fatty liver disease (NAFLD) is commonly associated with obesity. This randomized, double-blind, placebo-controlled trial aimed to evaluate the effects of turmeric on serum adiponectin and sirtuin 1 (SIRT1) levels, blood pressure, and body mass index (BMI) in patients with NAFLD. A total of 46 eligible patients with NAFLD (BMI, 25.0∼39....

Identifying retained activity participation to old age can improve age-related changes in balance and cognition function. Subjects ≥ 60 years were enrolled in this study. Balance and Cognitive function include working memory, executive function, and sustained and divided attention was evaluated with “Fullerton advanced balance”, “n-back”, “Wisconsi...

Background Cohort studies play essential roles in assessing causality, appropriate interventions. The study, Post-crash Prospective Epidemiological Research Studies in IrAN Traffic Safety and Health Cohort, aims to investigate the common health consequences of road traffic injuries (RTIs) postcrash through multiple follow-ups. Methods This protoco...

Aim: MiRNA's-143 and -206 are powerful apoptotic regulators in cancer cells. This study aimed to use miRNA-143- and 206-loaded poly(lactic-co-glycolic) acid (PLGA) nanoparticles conjugated with folic acid to induce apoptosis in the EL4 cancer cells. Materials & methods: The therapy was conducted in six groups: Treatment with both miRNAs simultaneou...

Importance: The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. Objective: To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic...

Magnesium and melatonin are known to exert multiple beneficial effects including anti-inflammatory and antioxidant actions. This study was designed to determine the effects of magnesium and/or melatonin supplementation on metabolic profiles in women with polycystic ovary syndrome (PCOS). This randomized double-blind, placebo-controlled trial was co...

Background Globally, colorectal cancer (CRC) is the third most common cancer and the second leading cause of death from cancer. Incidence and mortality from CRCboth can be reduced and prevented using screening and early detection programs. The current study aimed to assess the feasibility of the colorectal cancer screening program in Northwest of I...

Background This study aimed to investigate the effects of oral NaBut on metabolic parameters, blood pressure, and oxidative stress indices including glutathione peroxidase (GPx) and nitric oxide (NO) status in type 2 diabetic patients. Methods In the current interventional trial, 42 patients with type 2 diabetes mellitus (T2DM) were randomly alloc...

Background: Controlling and reducing salt intake are one of the solutions to overcome hypertension. This study aimed at determining the predictors related to salt control methods in Saqez urban population. Methods and materials: In the present cross-sectional study, the sample population was randomly selected through cluster sampling. Data colle...

Background: Colorectal cancer (CRC) is the third most common cancer and the second leading cause of death worldwide. However, CRC is considered as one of the most preventable cancers by which the mortality rates reduce about 60% through implementing the screening programmes. The present study aimed to evaluate the main barriers of CRC screening in...

Aim Antibiotics are widely used to prevent flare-ups after endodontic treatment of non-vital teeth. This systematic review assessed the effect of antibiotic administration on post-endodontic treatment pain and flare-up rate. Methods Five major databases including Web of Science, Cochrane Library, PubMed, Scopus and Embase were searched to identify...

Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to cartilage damage with mostly accompanied by metabolic disorders. This study aimed to investigate the effects of curcumin supplementation on metabolic parameters (lipid profile and glycemic indices), inflammatory factors, visfatin levels, and obesity values in women with RA. T...

This study aimed to collect and summarize test data and conduct a meta-analysis, with respect to the Multitarget Stool DNA test sensitivity and specificity, compared to colonoscopy. All manuscripts were screened for eligibility according to inclusion criteria. Participants were a normal population at an average risk of developing CRC. Intervention...

Background: Compared to non-smokers, non-daily smokers (NDS) experience a higher level of health risks associated to smoking. However, the most of them do not consider themselves as smokers. This study aims to investigate the prevalence of NDS and its predictors among students. Methods: This web-based study was conducted in Tabriz, Iran, from July...

Introduction: The Internet is an important source for health information and a medium for older adults' empowerment in health decision-making and self-caring. Therefore, we aimed to identify the potential motivators and probable barriers of e-health information-seeking behaviors (e-HISB) among older Iranian adults. Methods: A cross-sectional stu...

Background In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15–39 years) are lacking. To address this...

Objective: To assess psychometric properties of the European Quality of Life 5-Dimension 3-Level Version (EQ-5D-3L) commonly used tool for measuring road traffic injury (RTI) patients' quality of life. Methods: The psychometric study assessed the reliability and applicability of EQ-5D-3L through phone surveys, based on a national cohort platform...

The aim of this study was to determine the psychometric properties of the Persian version of pregnancy symptoms inventory. A methodological study. This study was conducted on 220 pregnant women. Construct validity was measured by exploratory factor analysis and confirmatory factor analysis. Reliability was measured by intra-class correlation coeffi...

Diabetes prevention programs have been developed in the different countries and it is therefore necessary to gain a better understanding of factors affecting the effectiveness of these programs for each society. Accordingly, the purpose of this study was to evaluate the effect of the National Diabetes Control and Prevention Program (NDCPP) on the b...

Introduction: Trauma is one of the major health problems worldwide. There are several indicators for predicting trauma mortality in the world, some of them are physiological, some anatomical, and some others are both psychological and anatomical. Our aim in this study was to compare the predictive power of GAP versus PHI in predicting mortality fro...

This updated meta-analysis sought to determine whether the pro-inflammatory potential of diet is a risk factor for breast cancer (BrCa) development, for the first time focusing on the effects of design heterogeneity. The search was performed using Scopus, PubMed, and Embase databases. Data were extracted from twenty-one eligible studies, including...

Abstract Background There is a lack of scientific literature on the application of fear appeals theories to evaluate lung cancer risk perception among smokers. The aim of the present study is to apply the Extended Parallel Process Model (EPPM) to discover the perception of the smokers about their lifetime risk of developing lung cancer (perceived s...

Introduction: This study aimed to assess the association between the survival of patients and outcomes in Brain Stroke (BS) in the presence of competing risks utilizing a Weibull parametric model. Methods: In this longitudinal study, 332 patients with BS were attended from Imam Khomeini Hospital in Ardabil, Iran. The stroke was diagnosed according...

Anemia is a globally widespread condition in women and is associated with reduced economic productivity and increased mortality worldwide. Here we map annual 2000–2018 geospatial estimates of anemia prevalence in women of reproductive age (15–49 years) across 82 low- and middle-income countries (LMICs), stratify anemia by severity and aggregate res...

Preclinical studies have indicated that T-cell immunoglobulin and ITIM domain (TIGIT) can substantially attenuate anti-tumoral immune responses. Although multiple clinical studies have evaluated the significance of TIGIT in patients with solid cancers, their results remain inconclusive. Thus, we conducted the current systematic review and meta-anal...