Mohammad Shamshir Alam

• PhD
• Head of Department at Qassim University

Herbal medicine, particularly in developing regions, remains highly popular due to its cost-effectiveness, accessibility, and minimal risk of adverse effects. Curcuma longa L., commonly known as turmeric, exemplifies such herbal remedies with its extensive history of culinary and medicinal applications across Asia for thousands of years. Traditiona...

Anthocyanins are natural, colored, water-soluble plant pigments that belong to the flavonoid, a subclass of the family polyphenol. Common dietary sources of anthocyanins include red and purple berries, grapes, apples, plums, cabbage, and other foods strong in natural colorants. Cyanidin, delphinidin, malvidin, peonidin, petunidin, and pelargonidin...

Hospital-acquired pneumonia is associated with greater rates of morbidity and mortality, which need to be identified and treat immediately and completely. We describe a case of a 70 years old female pneumonia patient, who arrived with abdominal pain and shortness of breath. She later developed mild hyponatremia and was at risk for developing syndro...

Colorectal cancer is a formidable health problem worldwide. In men, it's the third most prevalent cancer, while in women; it's the second most common. Colorectal cancer occurrence has been on rise in patients younger than age 50, often referred to as early-onset disease. The main aim of the present work was to provide an overview of medicinal plant...

Pregnant women and children are kept under special group of patients that needs extra efforts while selecting drug therapy for this group of patients. The use of anti-infective medicines in pregnant women and children has several limitations because of altered pharmacokinetics and pharmacodynamics of anti-infectives in these groups of patients, whi...

Oral health plays an important role in the general health and psychological state of the person, which affects general health and quality of life. Although oral health and general health are interrelated, preserving oral health in older age is undoubtedly more challenging with emerging challenges such as providing sufficient dental care. Despite th...

Fibro fatty infiltration of the myocardium, ventricular arrhythmias, and heart failure are all symptoms of arrhythmogenic right ventricular cardiomyopathy (ARVC). ARVC is a common cause of syncope, sudden death, ventricular arrhythmias in children and adolescents. Recent advancements in diagnostic techniques will aid in the early detection and corr...

Chronic low back pain (CLBP) is a pain that lasts at least three months in the lower back area. CLBP is the world's second greatest cause of disability, and it is a serious social and economic issue. CLBP has grown by more than 100% in the previous decade in the adult population and continues to rise substantially in the ageing population, impactin...

Small-cell lung cancer (SCLC) accounts for roughly 15% of all lung malignancies and is distinguished by a high proliferative rate, a proclivity for early metastasis, and a poor prognosis. Exposure to cigarette carcinogens is highly linked to SCLC. Only one-third of individuals have earlier-stage illness that is responsive to possibly curative multi...

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a kind of inflammatory neuropathy that has a gradual start and symmetrical sensory involvement. However, there are several clinical variances, suggesting that CIDP may represent a spectrum of linked disorders rather than a single disease entity. While the prevailing idea of CIDP pa...

Bladder cancer is the most frequent kind of urinary tract cancer. We will look at the most recent breakthroughs in the diagnosis and treatment of this illness in this review. The most significant tools in the diagnosis and follow-up of bladder cancer are cystoscopy and urine cytology. Several options have been examined, either to minimise the frequ...

In clinical practice, heart failure (HF) and renal impairment are coexisting illness which is linked with one another. Heart and kidney have bidirectional interrelationships , and it has been suggested that the kidney is the most significant organ involved in acute HF. The "cardio-renal syndrome" (CRS) is defined as acute or chronic malfunction of...

Malignant hyperthermia (MH) is a skeletal muscle pharmacogenetic disorder that manifests as a hypermetabolic response to powerful volatile anaesthetic gases like halothane, sevoflurane, desflurane, isoflurane, and the depolarizing muscle relaxant succinylcholine, as well as stressors like vigorous exercise and heat in human body. Anesthetics with a...

Adherence has been defined as the “voluntary, active, and collaborative involvement of the patients in mutually acceptable courses of behaviour to produce desired therapeutic effects”. Medication adherence generally illustrates the term as to whether the patients take their medicines as per prescription instruction and either they keep on to take a...

Adherence has been defined as the "voluntary, active, and collaborative involvement of the patients in mutually acceptable courses of behaviour to produce desired therapeutic effects". Medication adherence generally illustrates the term as to whether the patients take their medicines as per prescription instruction and either they keep on to take a...

Knowledge of the aetiological agents and its susceptibility to antimicrobial agents enables the clinician to initiate appropriate empirical antimicrobial therapy and guides diagnostic procedures. The aims of the study were to identify prevalence of bacterial pathogens causing sepsis and observe their antimicrobial resistance trends in hospitalized...

India is renowned for the development of health science based on Ayurveda, Unani, Siddha and Homeopathy. Ficus religiosa L. is most popular species in these indigenous system of medicines. In F. religiosa, entire plant parts like flowers, leaf, fruit, root, bark, inner part of stem, seeds are used as bioactive ingredients. Recently, some pharmacolo...

This is the advanced approach for development of pharmaceutical product with full range and specified limits of variables during procurements, storage and manufacturing process with a qualification, at desired level of quality within the limits of low and higher values of variables to ensures the Pharmaceutical product Quality by design (QbD) of ma...

Nutraceuticals are food of part of food material with the potential of maintaining health and may be characterized with physiological advantages or give assurance against perpetual maladies. Nutraceuticals play key role in maintaining the physiological variable in the normal range at cellular level or molecular level that's why, nutraceuticals migh...

Efficacy of pharmaceuticals dosage form generally depends on their formulation properties and manufacturing methods, hence it is likely that the quality of dosage form may vary. Renin acts on angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin-converting enzyme (ACE). Angiotensin II, a potent vasoconstrictor i...

Background/aims: Adverse drug reaction (ADR) is an appreciably harmful or unpleasant reaction, resulting from an intervention related to the use of a medicinal product. The present study was conducted in order to monitor the frequency and severity of ADR during antimicrobial therapy of septicemia. Methods: A prospective, observational, and nonco...

The present study describes an approach to synthesize the smaller chain tripeptides and tetrapeptides and to test their antinociceptive potency in mice. Based on rational drug design using hydrophobic ratio and total net charge as descriptors, five leads were selected, viz., Met-Arg-Tyr (MRY), Met-Val-Tyr (MVY), Met-Ile-Cys-Tyr (MICY), Met-Trp-Lys-...

The present study describes an approach to synthesize the smaller chain tripeptides and tetrapeptides and to test their antinociceptive potency in mice. Based on rational drug design using hydrophobic ratio and total net charge as descriptors, five leads were selected, viz., Met-Arg-Tyr (MRY), Met-Val-Tyr (MVY), Met-Ile-Cys-Tyr (MICY), Met-Trp-Lys-...

Hyperhomocysteinemia is highly prevalent in world population both in developing and developed countries. Elevated plasma homocysteine level has been associated with an increased risk for numerous pathological conditions that is not related to conventional risk factors. Various nutritional, hormonal, and genetic factors that are associated with elev...

Diabetes is leading cause for cardiovascular complication, drugs having cardioprotective and antihyperglycemic actions are constantly in search. Oral glucose elicits a three to four times higher peak insulin response compared with an equivalent dose of glucose, if infused intravenously. This is due to the reasons behind, the oral glucose causes a s...

Diabetes mellitus is the chronic disorder emerging as major world health problem which increases the rate of morbidity and mortality. The aim of the present study was to ascertain patterns of prescription of oral hypoglycemic agents to type 2 diabetic patients attending a university hospital, and to assess patient compliance. A prospective, observa...

To monitor the adverse drug reactions (ADRs) caused by antihypertensive medicines prescribed in a university teaching hospital. The present work was an open, non-comparative, observational study conducted on hypertensive patients attending the Medicine OPD of Majeedia Hospital, Jamia Hamdard, New Delhi, India by conducting patient interviews and re...

Study objective: To investigate the use of antihypertensive drugs in hypertensive patients and to identify whether such pattern of prescription is appropriate in accordance with international guidelines for management of hypertension. Methods: This was a prospective analysis. A prescription based survey among patients with established hypertension...

A prospective medicine usage evaluation based on prescription monitoring was conducted in the medicine OPD of our university teaching hospital to know prescribing trends of different categories of medicines. A total of 600 patients were included in the study comprising of 339 (56.5%) males and 261 (43.5%) females. The data were recorded within the...

Septicemia is a common clinical condition encountered in most of the hospitals in this region of the world. However, limited information is available in the Indian literature on antimicrobial usage in patients with suspected or proven cases of septicemia. The aim of the present study is on the one hand to describe the clinical characteristics of se...

The choice of antimicrobial therapy for bloodstream infections is often empirical and based on the knowledge of local antimicrobial activity profiles of the most common bacteria causing such infections. The present study was aimed to investigate frequency of bacterial pathogens causing septicemia and their antimicrobial resistant pattern in hospita...

The present study was conducted to monitor adverse drug reactions in patients of bronchial asthma in outpatient department and inpatient department of a university teaching hospital in South Delhi. About 200 patients irrespective of age and sex with established asthma were interviewed during the time period of January 2006 to April 2006 using struc...

Background: India has witnessed a rapidly exploding epidemic of diabetes in recent years and currently leads the world with the largest number of diabetic subjects in a single country. World Health Organization estimates that in 2000, 31.7 million individuals were affected by diabetes in India and these numbers will rise to 79.4 millions by the ye...

We explored the antibacterial prescribing patterns of physicians in ear, nose and throat (ENT) outpatient and inpatient departments (OPD, IPD) of a University Hospital, New Delhi, India. A prospective study was conducted, with a sample size of 276 patients, who visited the ENT OPD and IPD over a period of 4 months. It was found that 62.68% were mal...

Objective: To assess the role of pharmacist in community setting & consumer’s perception in National CapitalRegion.Setting: The study was conducted in National Capital Region of India during the year 2003-04.Method: Four pharmacy shops were selected for this study which were not attached to any hospital or clinic. Seventyseven consumers, who visite...

The aim of the present study was to monitor adverse drug reactions associated with antihypertensive drugs. The study was conducted in medicine out patient department of 150-bed Majeedia Hospital at Hamdard University Campus in New Delhi. The study was conducted by way of one to one patient interview by a registered pharmacist using a questionnaire-...

Objective : To assess the role of a pharmacist in a community setting and the consumer′s perception in the National Capital Region. Setting : The study was conducted in the National Capital Region of India during the year 2003 - 2004. Materials and Methods : Four pharmacies were selected for this study, which were not attached to any hospital or cl...

The aim of the present study was to monitor adverse drug reactions (ADRs) in the Medicine out patient department (OPD) of a University Teaching Hospital. Method A prospective evaluation of the ADRs reported in the Department of Medicine of our University Teaching Hospital over a period of 4-months was conducted. Results During the study period, a...

The study was conducted to find out the co-relation between serum retinol concentration and type 2 diabetes mellitus receiving antidiabetic treatment. There are conflicting reports in literature about the serum levels of retinol in Non-Insulin Dependent Diabetes Mellitus (NIDDM) patients. Therefore, in the present study serum retinol levels were ev...

The study was conducted to find out the co-relation between serum retinol concentration and type 2 diabetes mellitus receiving antidiabetic treatment. There are conflicting reports in literature about the serum levels of retinol in Non-Insulin Dependent Diabetes Mellitus (NIDDM) patients. Therefore, in the present study serum retinol levels were ev...

Two new pentacyclic triterpenoid glycosides isolated from the bark of Terminalia arjuna, have been characterized as olean-3α, 22β-diol-12-en-28-oic acid-3-O-β-D-glucopyranosyl (1→4)-β -D-glucopyranoside 1 and olean-3β,6β,22α-triol-12-en-28-oic acid-3-O-β-D-glucopyranosyl (1→4)-β-D-glucopyranoside 2 on the basis of spectral data analyses and chemica...