Mohammad Abu-Hegazy

• Neurology Professor
• Professor (Full) at Mansoura University

Background Electrophysiological techniques have been used for discriminating myoclonus from other hyperkinetic movement disorders and for classifying the myoclonus subtype. This study was carried out on patients with different subtypes of myoclonus to determine the electrophysiological characteristics and the anatomical classification of myoclonus...

Background: There is a need for effective, well tolerated and affordable drug for chronic migraine prophylaxis in low socioeconomic countries. Objective: To study the efficacy and safety of propranolol and sodium valproate (a food and drug administration approved and widely used treatment for prevention of migraine) as a prophylactic treatment in c...

Objectives: The purpose of this study is to assess the risk factors, biomarkers of stroke, mechanism, and outcomes of cerebral infarction among cancerous diseases. Materials & methods: 156 patients presented by acute ischemic stroke were divided into two groups: the first group included 78 ischemic stroke patients associated with different types...

Childhood brain tumor (BT) survivors have increased. Physical, cognitive, socialfunctions, and overall quality of life (QOL), may be diminished in response to tumors or their treatments in children. The tumor itself, surgery, chemotherapy,and radiotherapy can contribute to neurocognitive sequelae to debilitating levels.Short-term memory, attention,...

Purpose: To test the significance of FA and MD of diffusion tensor imaging in differentiating MS patients with normal and delayed VEP Material and Methods: This study was conducted upon 70 patients (aged 18-46 years: mean 32years) with multiple sclerosis that underwent diffusion tensor imaging and VEP. The average fractional anisotropy (FA) and mea...

Topiramate is an antiepileptic drug, used also for prevention of an episodic migraine. Its effects include sodium-channel-blocking activity, enhancement of cerebral GABA concentrations and antagonism of AMPA/kainate receptors, which leads to a decreased glutamate-mediated excitation. It is documented to possess weight reducing properties. It attenu...

Objective This study aimed to describe the behavioral and psychological symptoms of patients with different types of dementia and to correlate these symptoms to demographic and clinical variables of dementia such as age, sex, and score of cognitive assessment scales. Patients and methods This study was carried out on 73 patients with dementia. Pati...

Introduction Effective treatment must start as early as possible as brain cells die rapidly after stroke. To increase the number of patients who are eligible to receive tissue plasminogen activator, measures are needed to reduce the prehospital and inhospital delay time. The study aimed to evaluate the possibility of thrombolytic therapy in acute i...

Background: Individuals with elevated glycosylated hemoglobin (HbA1c) have a higher rate of microvascular complications, especially peripheral neuropathy. Objective: To find the relation between elevated (HbA1c) and the occurrence of peripheral nerve dysfunction in prediabetic individuals and to find the role of the inflammatory marker as, CReactiv...

Introduction: Many women think about reduction mammaplasty for different reasons. The effect of surgery on the beast sensibility is one of the greatest concerns after reconstructive reductive breast surgery through its affect on patient’s social life and psychological health. The dermatomal somatosensory evoked potential (D-SEP) is a new method to...

Background: Although it is relatively uncommon form of stroke, cerebral venous thrombosis (CVT) is still with difficulty in diagnosis and management. There is unsolved debate regarding the association of coagulation factor VII (FVII) R353Q polymorphism with venous thrombosis. Objective: We aimed to assess the association of FVII R353Q polymorphism...

Background: Radical resections of spinal ependymomas were made possible by many neurosurgeons with the advantages of electrophysiological spinal cord monitoring. Objective: To clarify the good neurological outcome prognostic factors and survival after surgical excision of spinal ependymomas. Methods: The current study enrolled 25 patients with spin...

Background: Meningiomas are primary and the second most common type of benign tumors of central nervous system derived from meningothelial cells. Objective: To evaluate the clinical outcome of posterior approach microsurgical resection of spinal meningiomas. Methods: Thirty-two patients underwent microsurgical resection via the posterior approach;...

Partial and generalized seizures often affect autonomic functions during seizures, and interictal and postictal periods. We investigated possible interictal electrocardiographic abnormalities in patients with generalized tonic-clonic seizures (GTCS), together with evaluating any structural heart changes by echocardiography in these patients in comp...

Purpose: This study was undertaken to determine the effect of adjuvant chemotherapy combined with reduced-dose craniospinal irradiation (CSI) on survival and neurocognitive sequelae of radiotherapy (RT) in patients with average- risk medulloblastoma above the age of 3 years. Methods: Thirty-three children between 3 and 10 years of age with avera...

Background: Approximately 60% of persons diagnosed with Systemic lupus erythematosus experience neurological complications at some time in the course of their disease. The most common of these neurological complications is neurocognitive abnormality. This study examined white matter structural and metabolic changes of brain in relation to cognition...

Objective The current retrospective study aims to evaluate the management of non-functioning pituitary macroadenoma through the assessment of experience on clinical, biochemical, radiological features, and treatment outcome of patients, and to identify prognostic factors affecting progression-free survival (PFS). Methods Data of 55 patients with n...

Objective The optimal treatment of patients with metastatic spinal cord compression (MSCC) is still being debated. This randomized trial was planned to compare the functional outcome and its related prognostic factors, toxicity and in-field recurrence of the three schedules of radiotherapy. Methods Two hundred and eighty five patients enrolled in...

Background: The most important risk factor of ischemic stroke is Diabetes Mellitus (DM) which is associated with accelerated atherosclerosis. Patients with type 2 DM have greater risk of carotid artery intima-media thickness which is important cause of cerebral ischemia. Objective: This study assessed the possible use of common carotid artery intim...

The authors conducted a prospective nonrandomised study about a new cervical disc prosthesis: the Discocerv Cervidisc Evolution. Fourteen patients (10 men and 4 women) were treated at a single mobile level, between July 2006 and November 2008. Their mean age was 40.8 years (range 31-56), and the mean clinical follow-up period was 12.8 months (range...

Background: Some authors reported significant relationship between migraine and low tension glaucoma. Objective: To investigate the prevalence of migraine in patients with low tension glaucoma and to evaluate MRI and EEG abnormalities in low tension glaucoma migraineurs. Methods: A prospective study conducted on 40 control and 39 patients with low...

Background: Epileptic vertigo is a rare form of partial seizures. It is often distinctive with sudden very brief episodes followed by rapid recovery without sequelae. Objective: Of this study was to establish the contribution of clinical semiology of epileptic vertigo in absence of convulsions and loss of consciousness. Patients and Methods: Thirty...

Background: Uremic neuropathy is one of the most debilitating symptoms associated with end stage renal disease. In adults the only potential cure for uremic neuropathy is renal transplantation. No studies have investigated the neurophysiologic abnormalities among pediatric renal transplant recipients. Objective: Our study aimed to describe the inci...

Uremic neuropathy is one of the most debilitating symptoms associated with end stage renal disease. In adults the only potential cure for uremic neuropathy is renal transplantation. No studies have investigated the neurophysiologic abnormalities among pediatric renal transplant recipients. The objective of this study is to describe the incidence, n...