Mohamed Moctar Mouliom Mouiche

• DVM ; PhD
• School of Veterinary Medecine and Sciences, University of Ngaoundere

The objective of this study was to measure the relative influence of the animal’s age, body condition score (BCS), glycemia at day of insemination (D0) and the livestock management system on the probability of conception and occurrence of embryonic mortalities. In this study, 81 inseminated cows both of the Gobra Zebu breed and crossbred were sampl...

Background Formal assessment of a surveillance system’s features and its ability to achieve objectives is crucial for disease control and prevention. Since the implementation of the mpox surveillance system in Cameroon, no evaluation has been conducted. Methods In a cross-sectional study, we assessed the performance of the mpox surveillance system...

In low- and middle-income countries, data on antimicrobial use (AMU) and antimicrobial resistance (AMR) in aquaculture are scarce. Therefore, summarizing documented data on AMU, antimicrobial residue (AR), and AMR in aquaculture in Africa is key to understanding the risk to public health. Google Scholar, PubMed, African Journals online, and Medline...

Background Antimicrobial resistance (AMR) is a major health concern with high rates in low-income countries. Bacteriology laboratories sustain the fight against AMR by providing antibiotic susceptibility testing (AST) results to ensure appropriate therapies. These laboratories generate a lot of data, which are usually used for prospective intervent...

Farm biosecurity has gained increasing attention worldwide during the last decades because of its role in reducing the occurrence of diseases and improving animal performance. Recently, recommendations to reinforce the concept of farm biosecurity in lower- and middle-income countries have been advised. Therefore, this review aims to provide a compr...

Background Multisectoral collaboration is crucial in effectively managing public health emergencies. The One Health approach, which emphasizes the interconnectedness of human, animal, and environmental health, has gained recognition as an effective strategy. This study analysis the factors influencing the implementation of the One Health approach i...

Rabies is a fatal disease occurring worldwide and especially in almost all the countries in Asia and Africa including Cameroon. Though animal and human rabies is prevalent in Cameroon, the epidemiology and socio-economic burden of the disease in the country is not known. Therefore, a 10-year (October 2004 to April 2013) retrospective study on the i...

Infectious diseases of livestock are a significant burden on animal and human health, particularly in Low and Middle-Income Countries. To prevent and control these diseases, an appropriate surveillance system based on suitable up-to-date epidemiological data is required. This systematic review looks at the available data on infectious diseases of l...

Monkeypox virus (MPXV) is a re-emerging virus of global concern. An outbreak of Clade I ACCEPTED MANUSCRIPT MPXV affected 20 captive chimpanzees in Cameroon in 2016. We describe the epidemiology, virology, phylogenetics, and clinical progression of this outbreak. Clinical signs included exanthema, facial swelling, peri-laryngeal swelling, and escha...

While the SARS-CoV-2 dynamic has been described globally, there is a lack of data from Sub-Saharan Africa. We herein report the dynamics of SARS-CoV-2 lineages from March 2020 to March 2022 in Cameroon. Of the 760 whole-genome sequences successfully generated by the national genomic surveillance network, 74% were viral sub-lineages of origin and no...

Background Globally, rotavirus infections are the most common cause of diarrhea-related deaths, especially among children under 5 years of age. This virus can be transmitted through the fecal-oral route, although zoonotic and environmental contributions to transmission are poorly defined. The purpose of this study is to determine the epidemiology o...

Background Rabies is a zoonotic disease of all warm-blooded animals including humans. There is a paucity of data on the status of rabies in wild animals in Cameroon and the disease is endemic in the country with dogs being the main source of transmission. Bat habitats are widespread in Cameroon, but there is limited information on the prevalence of...

To prevent and/or control infectious diseases in animal and human health, an appropriate surveillance system based on suitable up-to-date epidemiological data is required. The systematic review protocol was designed according to the PRISMA statement to look at the available data on infectious diseases of livestock in Cameroon from 2000–2020. Data w...

Background and objectives The emergence of extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) is causing increased morbidity and mortality around the world as a result of therapeutic failures. ESBL-E are priority pathogens due to their multidrug resistance (MDR). In Northern Cameroon, ESBL-producing bacteria, particularly in uri...

Introduction: Stakeholders involved in the implementation of the One Health (OH) welcome support for the operationalization of the approach and advice on how to address OH collaboration challenges. The IHR/PVS National Bridging Workshop (NBW) is an operational and outcome-oriented tool approach that allows animal health, human health and other rele...

Key Findings From the Living Safely With Bats book’s inception to distribution, the content development team engaged and collaborated with multilevel stakeholders from multiple countries on the diverse cultural contexts and local knowledge, attitudes, and behaviors regarding zoonotic diseases. The book development process provided insights on how...

One Health has received high attention in Africa in relation to health challenges at human-animal-environment interfaces. This has made the role of veterinary services more visible, while also exposing weaknesses in the capacity, resourcing, and workforce of the sector. Current assessment and planning tools do not sufficiently facilitate One Health...

Over the past decade One Health has received high attention in Africa in relation to health challenges at human-animal-environment interfaces. This has made the important role of veterinary services more visible, while also exposing weaknesses in the capacity, resourcing, and workforce of the sector. The interest and advancement made in One Health...

A cross-sectional survey was conducted to investigate the knowledge, attitudes, practices and zoonotic risk perception of Q fever among 484 selected cattle farmers (438) and veterinary personnel (46) in three northern regions of Cameroon. Data collection was conducted using questionnaires and responses were recoded into binary scale. An ANOVA test...

The health security planning process transforms recommendations from various evaluations into priority actions to strengthen countries' capacity for emergency preparedness using the One Health approach. Although the World Health Organization (WHO) has developed many tools to facilitate the planning process of a National Action Plan for Health Secur...

Background: Rabies is a zoonotic disease of all warm-blooded animals including humans. Though, there is little knowledge of the status of rabies in wild animals in Cameroon, the disease is endemic in the country with dogs being the main source of transmission. Bat habitats are widespread in Cameroon, but there is little information on the prevalenc...

Host-virus associations have co-evolved under ecological and evolutionary selection pressures that shape cross-species transmission and spillover to humans. Observed virus-host associations provide relevant context for newly discovered wildlife viruses to assess knowledge gaps in host-range and estimate pathways for potential human infection. Using...

African Horse Sickness (AHS) is a non-contagious viral disease that is endemic in sub-Saharan Africa countries and poses an important production and health threats of equines. AHS can induce up to 95% mortality in horses and 10% in donkeys. However, there is dearth of information of its epidemiology in donkeys in Cameroon. This study was therefore...

Ces dernières décennies, l’intensification de la production animale a été favorisée par l’usage des médicaments vétérinaires, en particulier les antibiotiques. Dans ce contexte, cette étude a été menée afin de rechercher la présence de résidus d’antibiotiques dans les denrées alimentaires d’origine animale comme la viande de bovins et les œufs de p...

African horse sickness (AHS), a highly fatal arbovirosis of equines is endemic in sub-Saharan Africa. However, its epidemiology is poorly known in Cameroon. This study aimed to investigate the prevalence profile and risk factors of African horse sickness in Cameroon. Horse sera were subjected to the ELISA blocking test for the determination of anti...

Lack of hygiene and biosecurity measures in poultry farms has influence on the emergence of pathogens and antimicrobial use. Antimicrobial residues in poultry meat and their excretion by poultry can exert a selective pressure and the occurrence of multidrug resistant bacteria in litter. The objective of this study was to investigate the relationshi...

An evaluation of the patterns of antimicrobial use in livestock can help understand the increasing level of antimicrobial resistance worldwide. This study aimed at evaluating antimicrobial usage in modern layer poultry farms in the West Region of Cameroon. In this light, 70 layer poultry farms and 4 veterinary pharmacies were surveyed. Data on anti...

The presence of veterinary drug residues in animal-derived foods (ADF) remains a public health concern in low-income countries such as Cameroon. This paper provides an overview of the current status of antimicrobial (AM) residues in ADF, veterinary legislation on the use of AM and perception of risk factors with emphasis on the need for sustainable...

Zoonotic spillover of animal viruses into human populations is a continuous and increasing public health risk. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) highlights the global impact of emergence. Considering the history and diversity of coronaviruses (CoVs), especially in bats, SARS-CoV-2 will likely not be the last to spillover...

Tuberculosis (TB) due to Mycobacterium bovis is a wasting disease of animals with severe public health significance. Though widely diagnosed in cattle and the performance of Tuberculin Skin Test (TST) at different cut-off points compared in various environmental conditions, there is dearth of information with respect to TB in goats in Cameroon. Thi...

Zoonotic spillover of animal viruses into human populations is a continuous and increasing public health risk. SARS-CoV-2 highlights the global impact emergence events can have. Considering the history and diversity of coronaviruses (CoVs), especially in bats, SARS-CoV-2 will likely not be the last to spillover from animals into human populations....

Host-virus associations have co-evolved under ecological and evolutionary selection pressures that shape cross-species transmission and spillover to humans. Observed virus-host associations provide relevant context for newly discovered wildlife viruses to assess knowledge gaps in host range and estimate pathways for potential human infection. Using...

Background: Disease prioritization aims to enhance resource use efficiency concerning human and animal health systems’ preparedness and response to the most important problems for the optimization of beneficial outcomes. In sub-Sahara Africa (SSA), several prioritizations of zoonoses and transboundary animal diseases (TADs) have been implemented at...

Retrospective data on antimicrobial use (AMU) within the period ranging from January 2012 to December 2015 was collected to assess the antimicrobial prescription patterns in pets (cats and dogs) treated by 16 veterinary private practitioners in the two main urban cities of Cameroon (Douala and Yaounde). The vet practitioners were interviewed in ord...

The present study was carried out to establish the spatiotemporal distribution of ASF between 2010 and 2017 in the Adamawa, North, and Far North regions of Cameroon. A retrospective study with data relating to the northern regions from epidemiological reports from target organizations in Cameroon was used to analyze outbreaks of ASF from 2010 to 20...

In an effort to strengthen global capacity to prevent, detect, and control infectious diseases in animals and people, the United States Agency for International Development’s (USAID) Emerging Pandemic Threats (EPT) PREDICT project funded development of regional, national, and local One Health capacities for early disease detection, rapid response,...

Brucellosis is regarded as one of the highest burden zoonotic diseases to persist in many regions globally. While sustained vaccination against B. abortus in an endemic setting can markedly reduce the prevalence of large ruminant and human brucellosis and benefit local livelihoods, the implementation of effective and sustainable control programmes...

Adenoviruses (AdVs) are diverse pathogens of humans and animals, with several dozen bat AdVs already identified. Considering that over 100 human AdVs are known, and the huge diversity of bat species, many bat AdVs likely remain undiscovered. To learn more about AdV prevalence, diversity and evolution, we sampled and tested bats in Cameroon using se...

Significance The recent emergence and spread of zoonotic viruses, including Ebola virus and severe acute respiratory syndrome coronavirus 2, demonstrate that animal-sourced viruses are a very real threat to global public health. Virus discovery efforts have detected hundreds of new animal viruses with unknown zoonotic risk. We developed an open-sou...

Residues of antimicrobials used in farm can exert selective pressure and accelerate the occurrence of multidrug resistant bacteria in litter. This study aimed to investigate the resistance profile of Escherichia coli isolated from poultry litter. A total of 101 E. coli strains was isolated from 229 litter samples collected and stored for two months...

Behavioral practices are one of the key factors facilitating zoonotic disease transmission, especially in individuals who have frequent contact with wild animals, yet practices of those who work and live in high-risk animal-human interfaces, such as wild animal ‘bushmeat’ markets in the Congo Basin are not well documented in the social, health and...

We conducted a pilot study to assess microbiological safety of chicken litter, an affordable organic and main fertilizer used in Cameroon and worldwide. A convenience sampling of 26 farms was done and a questionnaire was administered. Samples of litter were aseptically collected. E. coli and Salmonella spp. were isolated using CLSI standards. Antib...

Introduction: the International Health Regulation (2005) requires all countries to develop and maintain core capacities for preparedness and response to public health emergencies. The objective of this study was to assess Cameroon's capacities to prevent, detect and respond to public health threats through the Joint External Evaluation process. Met...

Antimicrobial resistance (AMR) is one of the greatest threats to public health of our time, affecting millions worldwide annually. Countries are working to strengthen detection and response to AMR through operationalizing national plans, strengthening sentinel surveillance sites, and reporting results of antimicrobial susceptibility testing (AST) t...

The use of antimicrobial (AM) in animal production is an important contributor to antimicrobial resistance (AMR) worldwide. Animal health professionals should play a key role in ensuring judicious use of AM. However, they are subjected to influence from clinical and non-clinical factors. The present study evaluates the perceptions and concerns of a...

Background The fight against Antimicrobial Resistance (AMR) demands strict training, monitoring, surveillance and strategic measures in the public health, animal and environmental sectors. In this context, a multi-sectoral One Health approach was developed in 2015 by the tripartite of the united nations agencies (WHO, OIE and FAO), in view of guidi...

Cameroon was one of the first countries in subSaharan Africa to adopt a One Health National Strategy in 2012. In 2014, the government created the National Program for the Fight Against Emerging and Reemerging Zoonoses (Zoonoses Program for short) to promote the One Health approach and operationalize the National One Health Strategy and encourage go...

PREDICT, a project of USAID’s Emerging Pandemic Threats (EPT) program, was initiated in 2009 to strengthen global capacity for detection of viruses with pandemic potential that can move between animals and people. PREDICT has made significant contributions to strengthening global surveillance and laboratory diagnostic capabilities for both known an...

Objective: Antimicrobial consumption surveillance is a useful tool for informing antimicrobial resistance control strategies and risk analysis. The present study was carried out to evaluate the consumption trends of antimicrobials for veterinary use in food-producing animals in Cameroon from 2014 to 2019. Methods: Data on quantities of classes of a...

Objective Antimicrobial consumption surveillance is a useful tool for informing antimicrobial resistance control strategies and risk analysis. The present study was carried out to evaluate the consumption trends of antimicrobials for veterinary use in food-producing animals in Cameroon from 2014 to 2019. Methods Data on quantities of classes of ac...

There is wide use of antimicrobial products in rural poultry farms in most sub-Sahara African countries. However, little is known of the factors that motivate rural poultry farmers towards antimicrobial use (AMU) and their level of awareness about antimicrobial resistance (AMR). This cross sectional survey was conducted to investigate the knowledge...

Pour limiter l'hémorragie des devises créée par les importations de produits laitiers et de satisfaire la demande interne en produits laitiers, le Sénégal a opté pour l’intensification de la production laitière par le biais des biotechnologies notamment l’Insémination Artificielle. Ainsi pour faire face, à cette situation plusieurs programmes ont é...

Objectives: The objective of this study was to present the JEE process in Cameroon’s as well as the country capacities to prevent, detect and respond to public health threats in accordance with the IHR (2005). Data for the 48 indicators within the 19 technical areas of the Joint External Evaluation (JEE) tool was examined. Results: Cameroon's overa...

Dengue fever is an understudied disease in many parts of Africa and little is known about its prevalence in Cameroon. We tested blood from 629 individuals from the South Region of Cameroon, collected over the course of one year, for flavivirus RNA using conventional broad range PCR. Flavivirus RNA corresponding to dengue virus (DENV) serotype 1 was...

Rift Valley fever (RVF) is a zoonotic vector borne infectious disease of major medical and veterinary importance particularly in sub-Saharan Africa. However, there is dearth of epidemiological knowledge of the disease in Cameroon. We conducted a cross-sectional study (January 2016–January 2017) to investigate the seroprevalence and potential risk f...

Background: Sub-Saharan African market is highly affected by counterfeit veterinary drugs. Though these counterfeit and non-compliance of drugs can induce adverse effects during their utilization, there is no monitoring system of veterinary medicines. The present pilot study was carried out in Cameroon to identify and describe suspected cases of a...

Background: Antimicrobial resistance (AMR) is widely acknowledged as a global health problem, yet in many parts of the world its magnitude is not well elucidated. A baseline assessment of the AMR prevalence is a priority for implementation of laboratory-based AMR surveillance This review, focused on a One health approach, aimed at describing the c...

Rodent adenoviruses are important models for human disease. In contrast to the over 70 adenovirus types isolated from humans, few rodent adenoviruses are known, despite the vast diversity of rodent species. PCR and Sanger sequencing were used to investigate adenovirus diversity in wild rodents and shrews in Cameroon. Adenovirus DNA was detected in...

Ten herd-level cross-sectional studies were conducted in peri-urban dairy production areas of seven West and Central African countries (Burkina Faso, Burundi, Cameroon, Mali, Niger, Senegal and Togo). The objectives were to estimate herd level Brucella spp. seroprevalence and identify risk factors for seropositivity. In each of the ten study areas,...

Aim: Staphylococcus with positive coagulase (SPC) is a major problem for beef consumers in the northern part of Cameroon. For this purpose, the SPC concentrations in beef produced and supplied in the northern regions were determined, as well as the resistance profile of these bacteria to antibiotics. Materials and Methods: A total of 125 samples w...

Background Brucellosis is a neglected debilitating zoonosis with a high prevalence in many developing countries. Bovine brucellosis is widespread in Cameroon but the epidemiological situation of human brucellosis is not known. A cross sectional study was carried to determine the seroprevalence and factors associated with bovine and human Brucellosi...

Brucellosis is an important notifiable disease of man and animals worldwide. The epidemiology and risk factors for the disease in cattle are better understood than for other animals in many developing countries wheresurveillance and control activities are biased towards Bovine and human Brucellosis.In Cameroon, Bovine Brucellosis is known to be wid...

Le développement de l’élevage passe par la lutte contre les différentes maladies animales. Pour cela, la réglementation du secteur pharmaceutique et l’assurance qualité du médicament constituent des atouts considérables. Cette étude avait pour objectif d’analyser la réglementation et l’organisation du marché des médicaments vétérinaires au Cameroun...

Senegal has embarked in artificial insemination (AI) to improve the productivity of small traditional dairy farms. However the success rate of the overall AI programmes remained low. This study aimed at assessing the incidence of embryonic mortality occurring in cows inseminated artificially by using progesterone and pregnancy associated glycoprote...

Bayesian model for the estimation of the value of characteristics of the tests.

A cross-sectional seroprevalence study was conducted on cattle in the North and Adamawa Regions of Cameroon to investigate the status of bovine brucellosis and identify potential risk factors. The diagnosis was carried out using the Rose Bengal Plate test (RBPT) and indirect ELISA (i-ELISA), while questionnaires were used to evaluate risk factors f...

Abstract | A two-phase study was carried out in the Far North region of Cameroon to describe the factors that could contribute to the spread of pathogens in animals kept in town, through traditional slaughterhouses. Seven traditional slaughterhouses located in the three main cities of this region (Maroua municipal, Kongola Djidéo, Kongola Djolao, M...

Intradermal tuberculin test (TST) is the choice method for diagnosis of bovine tuberculosis (Tb) in live animals. This work was done to assess the performance of single intradermal comparative cervical tuberculin (SICCT) test in randomly selected cattle in Maroua, Cameroon, against detection of Tb lesions and detection of Tb lesions plus acid fast...