Mohamed Tahar Taha Derouiche

University of Constantine 3 · Department of Pharmacy

Aim to determine some pharmacokinetic parameters in mice after oral and IV administrations of hydroalcoholic extract of Nerium oleander. Method Pharmacokinetic studies of oleandrin, a cardiotonic glycoside and main active compound of Nerium oleander were conducted in mice after administration of an IV dose (30 mg/kg) and a PO dose (150 mg/kg) of a...

Aim The aim of this work is the validation of a spectrophotometric method for the measurement of urinary thiocyanates. Method In acidic pH, thiocyanate ions give, with ferric nitrate, a red colour corresponding to 400 nm. The reagents required for the assay were: a stock solution of thiocyanate prepared by dissolving ammonium thiocyanate (NH4SCN)...

Aim To develop and validate an ultra-high-performance liquid chromatography coupled to diode array detection (UPLC-DAD) method for the determination of oleandrin, the active and toxic principle of Nerium oleander dried leaves and to assess oleandrin concentrations in samples collected in Eastern Algeria. Plant poisoning accounts for 3 to 4% of all...

Tetraclinis articulata (Thuya of Barbary), endemic to North Africa, is used as a traditional medicine for the treatment of many diseases [1]. We investigated the antidiarrhoel properties of the butanol extract of Tetraclinis articulata ( BETA ) in male and female Swiss albino mice to support its traditional use. The antidiarrhoeal activity of the p...

Introduction: The use of in vitro methods for the control of cosmetic products in developing countries must overcome cost, feasibility and an unfavourable regulatory environment. Among these products, shampoos occupy an important part of the market but present a number of risks related to their use like eye irritation. The aim of this work is to p...

Introduction. Le tilleul (Tilia cordata) est une plante largement utilisée en médecine traditionnelle sous forme d’infusion pour ses propriétés « calmantes ». Cette plante a fait l’objet d’une monographie par l’agence européenne des médicaments, qui a révélé de nombreuses lacunes relatives à son profil de sécurité et notamment son risque génotoxiq...

Introduction et but de l’etude Les tisanes sont des preparations largement utilisees par la population algerienne, du fait des « indications » medicales enoncees par les fabricants. Cela pose le probleme de la qualite de ces produits de sante en vente libre dans les officines pharmaceutiques. Le but de ce travail etait de verifier l’adequation et l...

The present work concerns the biological evaluation of the species Tetraclinis articulata of Cupressaceae family, after the extraction of the aerial parts of this plant ; we did analgesic biological test of its Extract: dichloro methane Extract, ethyl acétates Extract and n-butanol Extract using various in vivo models in mice. Our results showed th...

The present work concerns the biological evaluation of the species Ammoides atlantica of the Apiaceae family, after the extraction of the aerial parts of this plant; we did anti-inflammatory biological test of its Extracts: n-butanol extract and ethyl Acetate extract using various in vivo models in mice. Our results showed that the butanolic Extrac...