Mohamed S Attia

Mohamed S Attia
Ain Shams University · Department of Chemistry

Professor
early diagnosis of cancer diseases by nano optical sensors

About

167
Publications
24,309
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
1,670
Citations
Additional affiliations
October 2014 - June 2016
King Abdulaziz University
Position
  • Professor (Associate)
May 2012 - May 2017
Ain Shams University
Position
  • Professor
December 1999 - present
Ain Shams University
Position
  • Professor (Associate)

Publications

Publications (167)
Article
Full-text available
The sensitization of the excited triplet state of a novel symmetrical Bis(dialkylamino)phenoxazinium salt was developed in the presence of Hg(2+). This effect was used to determine the concentration of Hg(2+) in different water samples. The phenoxazinium salt sensor was characterized by different spectroscopic tools such as: UV, FTIR, NMR and fluor...
Article
Full-text available
A novel, simple, sensitive and precise spectrofluorimetric method is developed for measuring the activity of the α-amylase enzyme in human saliva. The remarkable quenching of the luminescence intensity at 634 nm of nano CdS doped in a sol-gel matrix by various concentrations of maltose (produced from the reaction of the enzyme with the starch subst...
Article
Highly luminescent complexes of Eu and Tb ions with norfloxacin (NFLX) and gatifloxacin (GFLX) were prepared in sol–gel matrix. The red and green emissions of Eu and Tb ions were obtained by the energy transfer from the triplet state of (NFLX) and (GFLX) to the excited emitting states (5D0 and 5D4) of Eu and Tb, respectively. The intensity of the e...
Article
This paper presents a novel, high sensitive, facile and rapid spectrofluorimetric method for the direct assessment of glucose in human serum samples. The strong fluorescence intensity of pyronin Y (PY) is found to be selectively quenched substantially by adding solutions of glucose. Therefore, a new quantitative method to determine glucose could be...
Article
Full-text available
Declining water resources and their contamination with chemicals risk the aquatic environment. Therefore, this work was devoted to designing a magnetically recyclable photocatalyst suitable for water treatment, namely, a TiO2−x/Fe3O4@g-C composite. Different preparation conditions were investigated together with the corresponding characteristics. T...
Article
Full-text available
Water is a fundamental resource, yet various contaminants increasingly threaten its quality, necessitating effective remediation strategies. Sustainable polymeric adsorbents have emerged as promising materials in adsorption-based water remediation technologies, particularly for the removal of contaminants and deactivation of water-borne pathogens....
Article
Full-text available
Rapidly developing two-dimensional (2D) materials, such as MoS2, graphene, and other transition metal dichalcogenides (TMDCs), have opened new possibilities for biosensing technologies. These materials exhibit unique electrical, mechanical, and optical properties, making them ideal candidates for highly sensitive and selective biosensors. This revi...
Article
Full-text available
Gold nanoclusters (AuNCs), with sizes below 2 nm, have emerged as remarkable nanomaterials exhibiting unique optical, electronic, and chemical properties. Their ultra-small size imparts advantageous characteristics, including high surface area, tunable fluorescence, and excellent biocompatibility, making AuNCs highly promising for diverse applicati...
Article
This work investigates the compositional dependence and thermal annealing of the morphological properties, electrical conductivity mechanisms and Mott's parameters of sprayed MoxW1-xO3 (x = 0, 0.05, 0.10 and 0,20) thin films. The prepared thin films were examined using field emission scanning electron microscopy (FE-SEM), energy dispersive X-ray an...
Article
Full-text available
A novel photoprobe, Tb–acetylacetone (Tb–ACAC) doped within a modified epoxy cellulose polymer immobilized with CA-125 monoclonal antibody, offers an accurate and highly selective method for early ovarian cancer (OC) diagnosis by detecting cancer antigen 125 (CA-125) in serum samples. This approach leverages quenching of the Tb–ACAC luminescence up...
Article
Full-text available
Correction for ‘Highly selective optical sensor N/S-doped carbon quantum dots (CQDs) for the assessment of human chorionic gonadotropin β-hCG in the serum of breast and prostate cancer patients’ by Yasmeen M. AlZahrani et al., RSC Adv., 2023, 13, 21318–21326, https://doi.org/10.1039/D3RA01570J.
Article
Full-text available
Correction for ‘Novel sensor for the determination of CA 15-3 in serum of breast cancer patients based on Fe–gallic acid complex doped in modified cellulose polymer thin films’ by Hind A. AlGhamdi et al., RSC Adv., 2023, 13, 21769–21780, https://doi.org/10.1039/D3RA02495D.
Article
Full-text available
Abstract The coelomic fluid (haemocoel) and coelomocytes of echinoderms were scarcely studied in Egypt. Remarkably, the most popular species is the five-arms starfish. While, in this work, the microscopical and chemical characteristics of the 7-arms giant starfish “Luidia maculata” were addressed. The starfish were gathered at 7 meters’ depth in th...
Article
Full-text available
Magnetic SiO2/Zn0.4Co0.6Fe2O4 aerogels were successfully prepared by sol-gel method with two different drying steps: ambient pressure drying (APD) and freeze-drying (FD). The surface chemistry of silica was modified to be hydrophobic by oleic acid. The prepared materials were fully characterized, displaying superparamagnetic behavior with saturatio...
Article
Full-text available
Fe-gallic acid MOF embedded in an epoxy methyl cellulose polymer (CMC) thin film was synthesized and characterized by different micro-analytical tools such as: FE-SEM/EDX, XPS analysis, XRD analysis, FT-IR, and fluorescence spectroscopy. Fe-gallic acid MOF doped in a stable CMC polymer thin film is used as a novel sensor to identify CA 15-3 in the...
Article
Full-text available
A low-cost, accurate, and highly selective method was used for the assessment of the human chorionic gonadotropin β-hCG in the serum of breast and prostate cancer patients. This method is based on enhancing the intensity of luminescence displayed by the optical sensor N/S-doped carbon dots (CQDs) upon adding different concentrations of β-hCG. The l...
Article
A novel, easy, touchy and selective spectrofluorimetric technique has been successfully applied for sensitive determination of High Sensitivity Cardiac Troponin (TNHS I) in the serum samples of patients suffering malignant tumors through the usage of optical sensor Eu3+-BINAM complex. The technique is primarily based on quenching of the Eu3+-BINAM...
Article
Full-text available
An accurate, sensitive and selective RP-HPLC-UV method has been established for the estimation of Molnupiravir (MOL) in pure bulk powder and pharmaceutical formulation. Separation was achieved on an Inertsil C18 column (150.0 mm × 4.6 mm, 5.0 μm), using a mobile phase of 20 mM phosphate buffer pH 2.5 : acetonitrile (80 : 20, v/v%) in isocratic mode...
Article
Full-text available
1,3,4-Thiadiazole molecules (1-4) were synthesized by the reaction of phenylthiosemicarbazide and methoxy cinnamic acid molecules in the presence of phosphorus oxychloride, and characterized with UV, FT-IR, 13C-NMR, and 1H-NMR methods. DFT calculations (b3lyp/6-311++G(d,p)) were performed to investigate the structures' geometry and physiochemical p...
Article
Full-text available
The importance of Echinoderms in Egypt grows day after day, as well as, the usage of the available untapped resources, in particular our interest in mariculture. Sea cucumber fishing was prohibited in Egypt and listed as endangered species, due to overfishing. Although the above decision was right at its time, it is not acceptable to us, due to the...
Article
Full-text available
Nanocomposite photocatalysts AgI-TiO 2 and AgO-TiO 2 were successfully synthesized by thermolysis method at 200°C/2 h. The composite photocatalysts were characterized by XRD, TEM and UV-Vis spectroscopy. The Efficiency of AgI-TiO 2 and AgO-TiO 2 photocatalysts in comparison with pure TiO 2 (P25) was tested by the photocatalytic degradation of Remaz...
Article
Full-text available
Correction for ‘Electrocatalytic hydrogen generation using tripod containing pyrazolylborate-based copper( ii ), nickel( ii ), and iron( iii ) complexes loaded on a glassy carbon electrode’ by Mohamed M. Ibrahim et al. , RSC Adv. , 2022, 12 , 8030–8042, https://doi.org/10.1039/D1RA08530A.
Article
Full-text available
Fly ash (FA) is a waste product generated in huge amounts by coal-fired electric and steam-generating plants. As a result, the use of FA alone or in conjunction with other materials is an intriguing study topic worth exploring. Herein, we used FA waste in conjunction with titanium oxide (TiO2) to create (FA-TiO2) nanocomposites. For the first time,...
Article
In³⁺ incorporated lithium ferrites have been synthesized via sol-gel auto-ignition route, and these were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and vibrating sample magnetometer (VSM). Thermal analysis of pure sample shows 12% weight loss in three successive steps observed by Thermogravimetric anal...
Article
Full-text available
Three transition metal complexes (MC) namely, [Tp MeMe CuCl(H 2 O)] (CuC), [Tp MeMe NiCl] (NiC), and [Tp MeMe FeCl 2 (H 2 O)] (FeC) {Tp MeMe = tris(3,5-dimethylpyrazolyl)borate} were synthesized and structurally characterized.
Article
Full-text available
A simple, accurate and fast method was developed for the assessment of 3-nitrotyrosine as a biomarker for the early diagnosis of liver cirrhosis with minimal hepatic encephalopathy (MHE) using a (Eu(TTA)3Phen) photo probe. 3-Nitrotyrosine can remarkably quench the luminescence intensity of the (Eu(TTA)3Phen) complex in DMSO at pH = 9 and λem = 617...
Article
The impact of Ni²⁺ and Zr⁴⁺ on the physical properties of LiFe2O4 ferrites is investigated and synthesized via the microemulsion technique. X-ray diffraction pattern of pure and substituted lithium ferrites exhibited spinel structure. The constant lattice increases with increasing dopants concentration up to x = 0.2 and decreases for higher x. The...
Article
This paper reports the impacts of nickel substitution on dielectric, magnetic, and structural characteristics of Ba4Cu2-xNixFe36O60 hexaferrites prepared via the sol–gel method. The sample was annealed for 5 h at 1200 °C. The crystalline structure, magnetic and dielectric features were examined by X-ray diffraction, vibrating sample magnetometer, a...
Article
Hepatocellular carcinoma (HCC) has become a pressing health problem facing the world today due to its high morbidity, high mortality, and late discovery. As a diagnostic criterion of HCC, the...
Chapter
The fast and continuous progress in diagnosis, treatment, and follow-up of different diseases and disorders based on the nanotechnology platform opened the door for new fields known as nanomedicine and nanostructures for use in different fields as targeted delivery. Nanocarriers are designed and fabricated from different materials such as metals, p...
Article
Metal-organic frameworks (MOFs) are significantly tunable materials that can be exploited in a wide range of applications. In recent years, a large number of studies have been focused on synthesizing nano-scale MOFs (nanoMOFs), thus taking advantage of these unique materials in various applications, especially those that are only possible at nano-s...
Article
A newly developed spectrofluorometric method is based on the fabrication of an optical cyanopyridine derived sensor, 4-(6-diaryl)-2-oxo -1,2-dihydropyridine-3-carbonitrile using microwave irradiation. The fluorescence intensity of the proposed chemo sensor was obviously quenched in DMSO owing to the presence of UO22+ ions at λex/λem = 320/360 nm. T...
Article
Full-text available
An innovative, simple and cost effective Tb3+-atorvastatin photo probe was designed and used as a core for a spectrofluorometric approach to sensitively determine two vital biological compounds in serum samples. Tb3+-atorvastatin complex displays a characteristic electrical band with λ em at 545 nm with significant luminescence intensity, which is...
Article
Full-text available
An innovative, simple and cost effective Tb3+-simvastatin photo probe was designed and used as a core for a spectrofluorometric approach to sensitively determine four vital biological compounds in different matrices. A Tb3+-simvastatin complex displays a characteristic electrical band with λ em at 545 nm with significant luminescence intensity, whi...
Article
Objectives/Hypothesis Chronic dizziness (CD) and imbalance have multiple etiologies. CD is strongly linked with psychiatric and psychological comorbidities, thus an interdisciplinary approach, including psychopharmacological interventions, is recommended. Despite the use of this comprehensive treatment approach, the recovery of individuals with CD...
Article
Chromium carbide coatings were grown on AISI O2 cold work tool steel via pack cementation method at the temperature of 900, 1000, and 1100 °C for 4, 6, 8h. The resulting coatings were examined using light microscopy LM, scanning electron microscopy/energy dispersive spectroscopy SEM/EDS, and X-ray diffraction XRD characterization techniques. The pr...
Article
Full-text available
A rapid and selective LC-MS/MS method is described for the simultaneous assay of Avanafil and Dapoxetine in human plasma via a protein precipitation (PP) sample preparation technique. Tadalafil was chosen as the internal standard reaching good recovery and reproducibility while diminishing the effects of the matrix. An Agilent Zorbax Eclipse XDB C...
Article
Full-text available
The urge for sensitive, facile, minimally invasive, and fast detection method of CA-125, a significant and crucial biomarker in ovarian malignancy, is currently substantial. This paper describes the detailed construction and characterization of a newly designed optical nano-biosensor to detect CA-125 accurately and sensitively. The fabricated senso...
Article
Development of promising technologies to remove thallium as a highly poisonous contaminant is of great attention to guarantee the sustainable supplement of safe potable water and human well-being all around the world. Recently, adsorption has been introduced as a noteworthy technique to remove trace amount of thallium. In the past, the rate of thal...
Article
Full-text available
The thrust to invent new materials and technology has been ever increasing due to technological challenges in progressive world. Among new materials, nanomaterials possess superior optical, electrical, magnetic, mechanical, and thermal properties, which have made them suitable for a multitude of applications. The present review paper deals with rec...
Article
Full-text available
An innovative, simple and cost effective Tb3+-acyclovir photo probe was designed and used as a core for a spectrofluorometric approach to sensitively determine two vital biological compounds in different matrices. The Tb3+-acyclovir complex displays a characteristic electrical band with λ em at 545 nm with significant luminescence intensity, which...
Article
A promising new eco-friendly sorbent from agricultural waste (silica/corncob nanocomposite) was successfully prepared and used for the removal of lead ions from the solution. The characterization and identification of the synthesized sorbents were investigated using different techniques. A comparative adsorption study between two sorbents was estim...
Article
Full-text available
A fast, sensitive one step UPLC ESI-MS/MS method was successfully applied for the simultaneous estimation of two concurrently administrated antidiabetic drugs, Metformin (MET) and Empagliflozin (EMPA) in human plasma. Metformin-d6 (MET-d6) and Empagliflozin-d4 (EMPA-d4) were utilized as internal standards. Extraction of the analytes from the human...
Article
Full-text available
Abstract We have been successfully used a new photoprobe based on Tb(III)(3‐acetyleindole)3 complex (TbAcI) as a novel, sensitive, accurate, and precise sensor for detecting shallow concentration (pico) of epinephrine (EPI) in different serum samples. Here, we report on and discuss the molecular structure of the interacting species using density fu...
Article
Full-text available
A low-cost, simple, and highly selective method was used for the assessment of total prostate specific antigen (tPSA) in the serum of prostate cancer patients. This method is based on quenching the intensity of luminescence displayed by the optical sensor Eu (TTA)3 phen/poly methylmethacrylate (PMMA) thin membrane or film upon adding different conc...