Mohamed Atta

Mohamed Atta
Alexandria University | AU · Department of Urology

Full Professor

About

57
Publications
1,858
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1,007
Citations
Citations since 2016
2 Research Items
156 Citations
2016201720182019202020212022051015202530
2016201720182019202020212022051015202530
2016201720182019202020212022051015202530
2016201720182019202020212022051015202530

Publications

Publications (57)
Article
Full-text available
Objective: To compare bilateral orchidectomy, as the classical ‘gold standard’ androgen-deprivation therapy (ADT), and ADT using a luteinising hormone-releasing hormone (LHRH) antagonist (degarelix) for the treatment of metastatic prostate cancer regarding their short-term biochemical efficacy, testosterone castrate level, tolerability, and effect...
Article
Full-text available
Objective The aim of our study was to report our experience with patients older than 70 years, incidentally diagnosed with prostate cancer during transurethral resection of the prostate for clinically suspected benign prostatic hyperplasia. Methods We retrospectively collected data of all patients who underwent TURP for benign prostatic hyperplasia...
Article
Full-text available
Objectives To assess whether the detubularised isolated ureterosigmoidostomy (DIUS) technique is safe for urinary diversion after radical cystectomy. Patients and methods The study included 10 patients (mean age 61.8 years) with invasive bladder tumour, operated at the Alexandria University, Egypt. The diversion in all patients was through a DIUS,...
Article
Full-text available
Objectives To assess the emptying pattern and patient satisfaction after constructing a detubularised isolated ureterosigmoidostomy (DIUS) following a cystectomy, introduced to overcome the poor outcome of conventional ureterosigmoidostomy, to improve the emptying pattern and accordingly patients’ quality of life. Patients and methods The study in...
Article
Full-text available
Percutaneous nephrostomy (PCN) has been widely used to drain an infected, obstructed kidney. Few major complications have been associated with it. Few publications have reported the misplacement of nephrostomy tube into the inferior vena cava (IVC), following percutaneous nephrolithotomy. We report a case of a misplaced silicon catheter, through th...
Article
Study Type – Harm (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Recent studies show no advantage of bowel preparation before ileal urinary diversion and that avoidance of bowel preparation led to early restoration of intestinal function and shorter hospital stay. However, this was not tested in a prospe...
Article
Full-text available
Bladder cancer represents a considerable issue in Egypt and the Middle East. Radical cystectomy and orthotopic neobladder represent the standard of care for managing cases with invasive bladder tumour. There are few cases reported in the literature considering the urothelial recurrence in the urethra, connected to neobladder. We are presenting a ra...
Article
Full-text available
Objectives Recurrence rates for patients with locally advanced renal cell carcinoma (LARCC) remain high. To date the predictors of recurrence in those patients remain controversial. The aim of the present study was to assess the relapse pattern in those patients and identify predictors for recurrence. Patients and methods We evaluated retrospectiv...
Conference Paper
INTRODUCTION AND OBJECTIVES Ureterosigmoidostomy is the first known continent urinary diversion. Initial reports were followed by unacceptable rate of morbidity and mortality due to ascending infection and obstruction as well as leakage of ureterointestinal anastomosis. Many technical modifications have been introduced to overcome these complicati...
Conference Paper
INTRODUCTION AND OBJECTIVES Ureterosigmoidostomy is the first known continent urinary diversion. Initial reports were followed by unacceptable rate of morbidity and mortality due to ascending infection and obstruction as well as leakage of ureterointestinal anastomosis. Many technical modifications have been introduced to overcome these complicati...
Article
Full-text available
Objectives Recurrence rates for patients with locally advanced renal cell carcinoma (LARCC) remain high. To date the predictors of recurrence in those patients remain controversial. The aim of the present study was to assess the relapse pattern in those patients and identify predictors for recurrence.Patients and methodsWe evaluated retrospectively...
Article
We determined the impact of the functional characteristics of the neobladder and urethral sphincter on continence results, and determined the most significant predictors of continence. A total of 88 male patients 29 to 70 years old underwent orthotopic bladder substitution with tubularized ileocecal segment (40) and detubularized sigmoid (25) or il...
Article
To determine the mechanism of urinary continence after repair of post-traumatic posterior urethral strictures by perineal anastomotic urethroplasty. Two groups of male patients were enrolled in this study. Group 1 consisted of 8 patients (mean age 31 years) who had undergone bulboprostatic anastomotic urethroplasty for strictures complicating a pel...
Article
A new modification for urinary diversion following cystectomy is presented. A total of 20 patients with bladder cancer who were treated with radical cystectomy underwent urinary diversion using a new technique. The sigmoid colon is dismembered approximately 30 cm. proximal to the peritoneal reflection and detubularized by anterior incision in its p...
Article
To determine the impact of preserving the prostatic apex on continence and urinary flow in patients with post-cystectomy intestinal bladder substitutes. A total of 38 male patients underwent radical cystectomy for bladder carcinoma and construction of a neobladder from ileum [9], sigmoid [9] or an ileocaecal segment [20]. The intestinal reservoir w...
Article
A technique is described to improve the evacuation pattern and, accordingly, the life-style of patients with ureterosigmoidostomy. An inverted U-shaped sigmoid colon is detubularized, and the left colon is fixed in continuity to the posterior wall of the rectal ampulla in line with the anorectal canal. The ureters are reimplanted into the sigmoid p...
Article
Objective To determine the impact of preserving the prostatic apex on continence and urinary flow in patients with post-cystectomy intestinal bladder substitutes.Patients and methods A total of 38 male patients underwent radical cystectomy for bladder carcinoma and construction of a neobladder from ileum [9], sigmoid [9] or an ileocaecal segment [2...
Article
Purpose: A technique is described to improve the evacuation pattern and, accordingly, the life-style of patients with ureterosigmoidostomy. Materials and methods: An inverted U-shaped sigmoid colon is detubularized, and the left colon is fixed in continuity to the posterior wall of the rectal ampulla in line with the anorectal canal. The ureters...
Article
To determine the risk factors and mechanism of urethral injury associated with pelvic fractures. A total of 203 consecutive male patients with pelvic fracture were studied prospectively, including a clinical examination, radiographic examination of the pelvis, excretory urography and retrograde urethrography. Thirty-nine (19%) patients had urethral...
Article
A new technique using an everting suture to construct a ureteral nipple is described. The method was used to create 28 ureteral nipples. A 2-zero silk suture is passed through the ureteral wall, transfixing the lumen, and is tied 5 cm. away from the ureteral wall. The ends are cut 10 cm. long. The suture is grasped within the ureteral lumen and wit...
Article
We attempted to determine how patients with an orthotopic bladder perceive the desire to void and the force achieved to evacuate the bladder. A total of 24 men who had undergone post-cystectomy bladder substitution (ileocecal in 12, sigmoid in 6 and ileal in 6) was evaluated subjectively an objectively by pressure-flow study 1 to 3 years postoperat...
Article
We studied the volume and pressure changes with time in detubularized and nondetubularized neobladders. Cystometry was performed at early and late followup in 54 male patients with post-cystectomy intestinal neobladders constructed from an intact ileocecal segment in 33, detubularized sigmoid in 11 and detubularized ileum in 10. With time the capac...
Article
The changes in certain characteristic features of schistosoma-associated bladder carcinoma are determined. A retrospective study was done of patients with schistosoma-associated bladder carcinoma treated between 1962 and 1967, and between 1987 and 1992. Mean patient age increased from 47 +/- 13.6 to 53 +/- 12.2 years and the male-to-female ratio ch...
Article
To evaluate the procedure of aspiration and tetracycline sclerotherapy in the management of simple ovarian cysts. Twenty-five cases of simple ovarian cysts were subjected to cyst fluid aspiration and 5% tetracycline injection under ultrasound guidance. Cytological examination of the aspirated fluid was carried out in 24 cases and the patients were...
Article
The urothelium plays an important role in the maintenance of normal bladder function. It provides a nonpermeable barrier to the contents of urine. The urothelium is directly involved in the transduction of both intravesical pressure and intravesical volume information to the afferent nerve fibers located within the lamina propria area. A third func...
Article
Fifteen patients suffering from symptomatic Gartner cysts were subjected to cyst fluid aspiration and 5% tetracycline injection of a similar volume (as that of aspirated cyst fluid) under local analgesia. Twenty-four hours later the injected tetracycline was re-aspirated until the cyst walls collapsed. The procedure was easy, inexpensive, acceptabl...
Article
A new technique for urinary reservoir reconstruction has been applied to 14 patients following radical cystectomy. The sigmoid colon was used in 10 cases and the ileum in 4. The pouch is constructed of adjacent detubularized intestinal segments. The continence mechanism is achieved by the formation of a double-jacket intestinal tube anastomosed to...
Article
Isolated detrusor muscle from control cats and cats parasympathetically decentralized for 3 and 10 weeks responded to electrical field stimulation by tetrodotoxin-sensitive, frequency-dependent contractions. There were no significant differences in the frequencies producing 50% response. However, the amplitude of the scopolamine-resistant contracti...
Article
A new technique for ileal nipple fixation is described in 6 post-cystectomy patients (4 with an ileal bladder substitute and 2 with an ileal reservoir) for the prevention of reflux. Nipple formation is helped by deperitonealization and defatting of the nipple mesentery. A full circumferential incision is made, except for the mesenteric border, and...
Article
It has been shown previously that partial bladder outlet obstruction in the rabbit results in changes in detrusor contractility and biochemical profile [Malkowicz et al., 1986]. The present study was conducted in the same animal model to define the nature and evolution of concomitant structural neuromuscular changes in the detrusor, as the basis fo...
Article
It has been shown previously that both degenerative and regenerative muscle cell changes occur in the partially obstructed rabbit detrusor and are largely reversed after relief of the obstruction [Elbadawi et al., 1989]. In the present study, we quantitated these changes in the same animal model to define their chronologic evolution. Specimens for...
Article
Histochemical changes in bladder innervation have been described in various types of clinical and experimental neurogenic voiding dysfunction. Recent studies in the cat have shown that both decentralization and postganglionic “denervation” lead to ultrastructural changes in muscular innervation of the bladder base. The present study was conducted t...
Article
Previous studies have shown that unilateral decentralization of the feline bladder by sacral ventral rhizotomy results in ultrastructural neuromuscular changes in the bladder base. In the present study, the neuromuscular ultrastructure of the feline bladder base was studied in twenty sexually mature adult male cats 1–4 and 6–10 weeks following bila...
Article
It has been shown previously that unilateral parasympathetic decentralization of the feline bladder by sacral ventral rhizotomy results in early degenerative and eventual regenerative ultrastructural neuromuscular changes in the bladder base. The present study was conducted to define the effects of unilateral parasympathetic decentralization by pel...
Article
We have shown previously by electron microscopy that somatomotor denervation of the male feline rhabodsphincter by bilateral sacral ventral rhizotomy leads to early loss of cholinergic axons innervating its end-plates, and to its eventual purely autonomic reinnervation by cholinergic and adrenergic axons. The present study was conducted to find out...
Article
Ordinary somatic striated muscle with purely somatomotor innervation undergoes atrophy with fibrosis when completely denervated. On this basis, it has been suggested that vesical outlet “obstruction” in voiding dysfunction resulting from lower-motor neural lesions is due to fibrosis of a denervated rhabdosphincter. We have shown previously that: (1...
Article
We have shown previously that myofibers of the male feline rhabdosphincter are innervated by somatomotor end-plates as well as nonspecialized surface junctions by autonomic cholinergic and adrenergic axons. Shortly after sacral ventral rhizotomy, the somatomotor cholinergic axons innervating the plates disappear, but the autonomic cholinergic and a...
Article
Partial bladder outlet obstruction is a commonly encountered pathophysiologic state. Recently we have reported on the rapid nature of the contractile and functional changes that occur in the rabbit urinary bladder within one week of chronic partial obstruction. The purpose of this present study is to investigate the ability of the bladder to recove...
Article
To examine the pharmacologic nature of parasympathetic decentralization on feline vesical smooth muscle, male cats were subjected to bilateral ventral rhizotomy from levels lumbar 7 to coccygeal 1 and studied at 1 and 3 months. By employing manual bladder decompression twice daily, compensatory bladder hypertrophy was absent or minimal in all speci...
Article
The male feline rhabdosphincter was studied ultrastructurally to define the patterns of innervation of its fibers. Two types of neural junctions were observed: classical neuromuscular junctions with motor end-plates (of both the en plaque and en grappe types), and surface junctions without any specialization of the related muscle fibers. The former...
Article
Innervation of the male feline rhabdosphincter was studied ultrastructurally 1 and 2 weeks following bilateral sacral ventral rhizotomy. In all samples, there was virtual loss of myelinated axons, degeneration and loss of the axonal element of all motor end-plates, and preservation of autonomic nonrnyelinated (cholinergic, adrenergic, and probable...
Article
The morphology of cholinergic and adrenergic muscular nerves of the feline bladder base was studied ultrastructurally 2, 3, and 4 weeks following its decentralization by unilateral sacral ventral rhizotomy. In all samples, there was widespread transsynaptic degeneration of cholinergic axon terminals and varicosities, with loss of neuroeffector junc...
Article
We have shown previously that vesicourethral decentralization by unilateral sacral ventral rhizotomy in the cat results in sequential degenerative and regenerative ultrastructural changes in intrinsic nerves of the bladder base. The present study in the same model provides evidence that these neural changes are associated with both degenerative and...
Article
The ultrastructure of muscular innervation of the feline bladder base was studied eight and ten weeks following its decentralization by unilateral sacral ventral rhizotomy. In all samples, there was widespread regeneration of cholinergic axons that displayed initial transsynaptic degeneration a few weeks after the operation, with re-formation of ch...

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Projects (2)
Project
Trying to modify guidelines, so we may be able to avoid 2nd look cystoscope for a selected group of patients with newly diagnosed NMIBT.