Mohamed Abdullah Al-Kindi

Sultan Qaboos University | SQU · Department of Pathology, College of Medicine and Health Sciences

Objectives: Osteomyelitis, marked by bone inflammation due to microbial infection, presents significant healthcare challenges. While the protective role of biofilm in bacterial immunity and persistence is well-documented, its direct impact on bone degradation in osteomyelitis remains inadequately characterized. This study aims to comprehensively ex...

Introduction Malformin A1 (MA1), a compound derived from marine sources, has high toxicity towards both cisplatin-sensitive and resistant ovarian cancer cell-lines. We investigate the impact of MA1 on cytoskeletal network and elucidate the mechanism of cell death in ovarian cancer. Methods We assessed the effects of MA1 on cell shape, locomotion,...

In this study, bacteria residing in the gut of the rice weevils (Sitophilus oryzae L.) (Coleoptera: Curculionidae) feeding on aflatoxin-contaminated corn kernels were isolated and evaluated for their ability to suppress Aspergillus flavus and to remove/degrade aflatoxin B1 (AFB1). Four morphologically distinct S. oryzae gut-associated bacterial iso...

This study aimed to improve biochar’s quality for arid land applications by using elemental sulfur as a pH reducer agent co-applied with compost or vermicompost as biological activators. Biochar pH was decreased by the addition of elemental sulfur, with the highest reduction from 8.1 to 7.2 occurring when co-amended with vermicompost. Elemental sul...

Introduction: Circulating microparticles (MP) are being described as potential biomarkers for disease activity in a variety of conditions including sickle cell anemia (SCA). However, relatively little is known about the influence of spleen status on MP levels in patients with SCA. Methods: Using a prospective study design we characterize circula...

Biochar is rapidly gaining worldwide interest as an agro-technology for increasing soil health and carbon storage. This study investigated the physicochemical characteristics and impact on soil microbes of biochar amendments from three feedstock sources: date palm leaves (D), mesquite plants (M) and sludge compost (S.C.); pyrolyzed at 450 ℃, 600 ℃...

Purpose Osteomyelitis is an infectious bone process leading to bone necrosis and destruction. Published reports on pathogen biofilm thus far have focused on indirect bone resorption mediated by host cells and factors secondary to immune system activation. However, direct bone resorption due to biofilm pathogen has not been adequately studied yet. T...

Oxidative stress plays a pivotal role in the development of diabetes and hyperglycaemia. The protective effects of natural extracts against diabetes are mainly dependent on their antioxidant and hypoglycaemic properties. Broccoli (Brassica oleracea) exerts beneficial health effects in several diseases including diabetes; however, the mechanism has...

This study was conducted to measure the electromagnetic waves (RFW) emitted by different mobile phones and to further examine the effects of these waves on the living cells. TriField meter Model 100XE was used to measure the electromagnetic waves (mW/cm2) emitted by different mobile phones while receiving a call. To explore the effects of electroma...

There is a global increase in the popularity of water-pipe tobacco smoking including in Europe and North America. Nevertheless, little is known about the male reproductive effects of water-pipe smoke (WPS), especially after long-term exposure. Here, we assessed effects of WPS exposure (30 min/day) in male mice for 6 months. Control mice were expose...

Breast cancer (BC) is the most common cause of cancer-related death worldwide. Although platinum-based drugs (PBDs) are effective anticancer agents, responsive patients eventually become resistant. While resistance of some cancers to PBDs has been explored, the cellular responses of BC cells are not studied yet. Therefore, we aim to assess the diff...

Objectives: Marine organisms are a rich source of bioactive molecules with potential applications in medicine, biotechnology and industry; however, few bioactive compounds have been isolated from organisms inhabiting the Arabian Gulf and the Gulf of Oman. This study aimed to isolate and screen the anti-cancer activity of compounds and extracts fro...

The feasibility of date seed ash, a low-cost agricultural by-product in Oman, for the removal of boron from aqueous solution was investigated. The aim of this study was to understand the mechanism that governs boron removal from seawater using date seed ash as an adsorbent in batch adsorption experiments. The effects of adsorbent dose, contact time...

Seasonal fluctuations in the plasma progesterone (P), estradiol (E2) and testosterone (T) were monitored throughout the year using the highly sensitive method (HPLC/MS-MS). For the progesterone receptor (PR) expression, immunohistochemistry was used. Transmission electron microscopy was used to localize the ultrastructural steroidogenic features (U...

Azoxymethane (AOM) is a potent carcinogenic agent commonly used to induce colon cancer in rats; the cytotoxicity of AOM is considered to mediate oxidative stress. This study investigated the chemopreventive effect of three natural extracts [pomegranate peel extract (PomPE), papaya peel extract (PapPE) and seaweed extract (SE)] against AOM-induced o...

The Arabian tahr/ibex is a small species of goat-antelope-like animal, indigenous to the United Arab Emirates and with a larger population in Oman. Although the animal was discovered in 1894, its numbers continue to decline, and the animal has been classified on the IUCN red list as an endangered species. Little is known about the male reproduction...

Inhaled ultrafine (nano) particles can translocate into the bloodstream and interact with circulatory cells causing systemic and cardiovascular events. To gain more insight into this potential mechanism, we studied the interaction of diesel exhaust particles (DEP) with human, rat and mouse erythrocytes in vitro. Incubation of erythrocytes with DEP...

A novel layered compound Al0.3V2O5·5H2O was successfully prepared and characterized using powder X-ray diffraction, Thermal analysis, scanning and transmission electron microscopes. The new layered Al0.3V2O5·5H2O has like-nanowires shape and the layered structure was stable until 400 °C. At higher temperature (500 °C), it decomposes to orthorhombic...