Moamar Al-Jefout

• MD, PhD
• Professor (Associate) at United Arab Emirates University

Open access: https://www.jmig.org/article/S1553-4650(24)00073-6/fulltext or click the DOI above. // Endometriosis research has not progressed at a pace in proportion to disease severity and the negative impact on women’s quality of life. Furthermore, advancement in our understanding of this condition requires a quantum shift based on new theories o...

This is the first guidelines for adenomyosis from the Asian Society of Endometriosis and Adenomyosis.

This case report illustrates an incidental finding of asymptomatic Fitz-Hugh-Curtis syndrome in a 34-year old woman undergoing laparoscopy due to a spontaneous ruptured ectopic pregnancy after bilateral tubal ligation. To our knowledge, this is the first case that reported an atypical presentation in a twofold aspect: the presence of perihepatic ad...

Introduction: Endometriosis has a negative effect on health-related quality of life (HRQoL), wellbeing and daily functioning. Endometriosis is an under-researched condition within non-western populations. Cultural representations are needed to understand the relative roles of societal norms, traditional factors, and religious sensitivities on the i...

Introduction: High prevalence of gynecological conditions in women of Middle Eastern origin is reported, likely due to regional risk factors and mediators. The objective of this systematic review and meta-analysis is to investigate the prevalence of polycystic ovary syndrome (PCOS), endometriosis, uterine fibroids, and adenomyosis in women of Middl...

Aim . Sexual function plays an important role in normal human life, along with sleep and food. As it is behind the main human motivations and can manifest itself in any phase of sexual activity or at any time of sexual life, the sexual function is considered as an important factor in determining the quality of life in adults. Here we aimed to estim...

Along with sleep and meal, sexual function is one of the main human motivations and its impairment can drastically reduce the quality of life in women. This condition is often overlooked and untreated. The prevalence of sexual dysfunction in the female population of different countries ranges from 25 to 63%, being particularly high in Siberia (55.9...

Background: Female genital mutilation/cutting (FGM/C) is a common practice in developing countries, including the UAE, and presents a major health problem.

Background: Female genital mutilation/cutting (FGM/C) is a common practice in developing countries, including the UAE, and presents a major health problem. Methods: A questionnaire-based cross-sectional study was conducted among 1035 participants: 831 (80.3%) females and 204 (19.7%) males. Results: The number of women with FGM/C was 344; hence...

Despite extensive investigations, the causes of endometriosis and mechanisms of its development are largely unknown. Here we review the existing theories, analyzing the risk factors and triggers of endometriosis. We suggest that all cases of endometriosis are initiated through a common pathophysiological mechanism which involves all downstream mole...

Caesarean scar ectopic pregnancy (CSEP) is considered an extremely rare entity, but life threatening, however, with the increase in C/S rates it isbecoming a more common finding. To explore the possibility of utilizing ultrasound guided transvaginal aspiration and injection of 50 mg methotrexate followed by mechanical disruption as a promising prim...

Background: Bearing a child is one of the most important motivations for human beings with regard to the continuation of life. People's perception of infertility is contingent upon various diverse cultural factors. Objective: This study aims to explore the perceptions of infertility in infertile women in the United Arab Emirates. Methods: This qu...

Purpose: To evaluate the effect of balanced hypocaloric diet therapy on the anthropometric and basic metabolic indicators in obese women with infertility. Methods: The follow up interventional clinical study included 23 infertile women in reproductive age with grade I gluteofemoral obesity. All patients have prescribed a balanced hypocaloric diet (...

Objectives: The aim of this study was to evaluate the perception and experience of recurrent pregnancy loss through the perspective of women in the United Arab Emirates (UAE). Materials and Methods: This qualitative study was conducted in 2017 and 12 women with recurrent miscarriage were interviewed, using purposive sampling method, in the Medical...

The true prevalence and risk factors for endometriosis among women in UAE are unknown. Objectives: To estimate the prevalence of endometriosis among women in UAE aged 18 to 55 years, risk factors and related health problems. A questionnaire-based cross-sectional study exploring information about reproductive events and gynecological problems includ...

Polycystic ovary syndrome (PCOS) is a common problem among Arab women and is the main cause of infertility due to anovulation. This study investigates insulin resistance (IR) and obesity in different PCOS phenotypes among infertile women (n = 213), of whom 159 had PCOS and 54 women without PCOS, recruited as a control group. Biometric, hormonal and...

Objective This study sought to explore the prevalence and clinical manifestations of endometriosis in young women with chronic pelvic pain (CPP) refractory to conventional medical therapy. Methods This prospective clinical interventional study was conducted in two general and private hospitals in the city of Al-Karak in Jordan. A total of 28 femal...

Polycystic ovary syndrome (PCOS) is a common problem among Arab women and is the main cause of infertility due to anovulation. This study investigates insulin resistance (IR) and obesity in different PCOS phenotypes among infertile women (n = 213), of whom 159 had PCOS and 54 women without PCOS, recruited as a control group. Biometric, hormonal and...

The true prevalence and risk factors for endometriosis in Jordanian women are not known. To estimate the prevalence of endometriosis, risk factors and related health problems in Jordanian women aged 15–55 years. A questionnaire-based cross-sectional study. Among the all-female participants (n=1772) endometriosis diagnosis was reported in 45 partici...

The 3rd International Consensus Workshop on Research Priorities in Endometriosis was held in São Paulo on May 4, 2014, following the 12th World Congress on Endometriosis. The workshop was attended by 60 participants from 19 countries and was divided into 5 main sessions covering pathogenesis/pathophysiology, symptoms, diagnosis/classification/progn...

Background & Aims: The eutopic endometrium in women with endometriosis harbor small nerve fibres. This study aimed to explore the clinical usefulness of office endometrial biopsy to detect endometrial nerve fibres as diagnostic test for endometriosis in the work up of women with infertility and no endometrioma. Material & Methods: A cohort of 28 Jo...

To evaluate the efficacy of continues Norethisterone acetate, 5 mg (NET-A; group N) versus cyclical combined oral contraceptive pill (COC) consisting of drospirenone 3 mg/ethinyl estradiol 20 μg pills (group P) in treating dysmenorrhea in young adult females. This prospective, open-label, non-randomized study included 38 patients: 20 patients (Grou...

Background: Jordan has a low prevalence of the Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS). However, HIV/AIDS is an important global public health issue and medical students need to be well-informed about it. Aims: To assess Mutah Medical School students' knowledge about HIV/AIDS and to explore their attitudes towar...

Objective: Etonogestrel subdermal hormonal contraceptive implant (Implanon®) is a popular and effective contraceptive. However, some users discontinue it for a variety of reasons. To explore the experience of Jordanian women with Implanon. Methods: This survey was undertaken with 69 women who had used or were using Implanon. Data was obtained throu...

To establish the prevalence and impact on quality of life of dysmenorrhea among young adult Jordanian females. Cross-sectional study based on quantitative self-reported anonymous questionnaire. University-based study. A total of 272 female medical students (aged 19-25 years). None. Self-reports of menstruation-related pain symptoms and methods of d...

Background: Abdominal wall endometriosis is to be found to increase due to the rapid increase of caesarean section rates. The Case: The author report a case of a 44 year old multiparous woman diagnosed with recurrent abdominal wall endometriosis after cesarean section few years ago for which she underwent wide surgical excision and was treated medi...

To investigate the immune environment of endometrial polyps (EPs). Prospective case-control study. Teaching hospital and university research laboratory. Reproductive-age women undergoing hysteroscopy dilation and curettage for benign indications. Samples were collected from women with (n = 23) and without (n = 40) EPs. Endometrial samples were immu...

Introduction Current treatment of endometriosis is still associated with undesirable side effects and high recurrence rates, thus there is a need to develop more specific therapeutical strategies. Since it is assumed that endometrial stromal cells play a pivotal role in the establishment of this disease, terminal differentiation of these stromal ce...

To assess the impact of pre-hCG elevated progesterone on live birth outcomes during GnRH agonist long down regulated protocol assisted reproduction cycles. Retrospective cohort study. Single Centre Private IVF Clinic. A total of 582 consecutive cycles of IVF/ICSI in 2003. All patients underwent a long down-regulation protocol, controlled ovarian st...

Desmoid tumors are cytologically bland fibrous neoplasms originating from musculoaponeurotic structures throughout the body. The cause of desmoid tumors is uncertain, but may be related to trauma or hormonal factors, or may have a genetic association. These tumors can be found in some young women during pregnancy or just after giving birth. We repo...

Diagnosis of endometriosis currently requires a laparoscopy and this need probably contributes to the considerable average delay in diagnosis. We have reported the presence of nerve fibres in the functional layer of endometrium in women with endometriosis, which could be used as a diagnostic test. Our aim was to assess efficacy of nerve fibre detec...

Endometrial polyps are benign lesions frequently identified in women with infertility or abnormal uterine bleeding in the reproductive and postmenopausal phases We report the striking observation that the numbers of activated mast cells expressing tryptase are increased more than sevenfold throughout the cycle in endometrial polyps (n = 20) compare...

Endometriosis is a disease that still presents many puzzles to clinicians and basic research scientists. Until recently, it has been regarded as a condition that arises when normal endometrium adheres to the peritoneal surface and then grows into an `inflammatory' lesion, which adversely influences local reproductive tract function and causes pain....

The purpose of this study was to evaluate endometrial biopsy and curettage in detecting small nerve fibers in eutopic endometrium for diagnosis of endometriosis. Endometrial biopsies with precise, consistent technique and curettings were taken from 37 women (20 with endometriosis and 17 without endometriosis). Sensitivity, specificity, and positive...

Adolescent familial endometriosis may cause severe and persistent symptoms that are disruptive to lifestyle. Treatment may be difficult in many cases. We describe the novel and successful first use of a simultaneous combination of a levonorgestrel intrauterine system and an etonogestrel subdermal implant in a teenager with severe pain symptoms as a...

Endometriosis is a common gynaecological disease that can cause severe pelvic pain such as dysmenorrhoea and dyspareunia, however the mechanisms by which pain is generated are not well understood. Nerve fibres in endometriotic plaques have been reported by several authors. We have recently demonstrated the presence of unmyelinated sensory nerve fib...

The effect of early- and mid-follicular LH concentrations on the ovarian response and pregnancy outcomes was evaluated in women receiving pituitary down-regulation with a GnRH agonist and ovarian stimulation with recombinant FSH (rFSH) during IVF/ICSI treatment. Blood samples were collected prospectively from 701 cycles (560 patients) of assisted r...