Miruna Maria Apetroaei

Carol Davila University of Medicine and Pharmacy | UMF CD · Department of General and Pharmaceutical Microbiology

This paper examines the economic impact of the COVID-19 pandemic on private dental practices in Bucharest, Romania, focusing on the influence of practice size and employee numbers. A comparative analysis was conducted across three years: 2019, 2020, and 2021, utilizing data sourced from the Romanian Finance Ministry. In 2019, there were 1,735 activ...

Diabetes is a complex metabolic disorder characterized by chronic hyperglycaemia and associated with significant oxidative stress, which contributes to the progressive damage of vital tissues. This study evaluates the potential benefits of probiotics in managing oxidative stress by administering them to both untreated diabetic groups and diabetic g...

Introduction: Telomeres, repetitive DNA sequences at chromosome ends, shorten with cell division, countered by telomerase. Short telomeres are linked to cardiovascular disease (CVD), alongside its risk factors like aging, hypertension, diabetes, obesity, inactivity, and smoking. Many studies have claimed the implication of TL in cardiac diseases. T...

The degree of deacetylation, DDA is the most important characteristic for a specific chitosan sample as it mainly influences its chemical and biological properties. Several natural wastes may be used as sources for chitin as for example crabs’ and shrimps’ exoskeletons, and the yield of chitosan extraction is generally small and depends on the chit...

The lack of clear prescribing protocols in the field of probiotics creates difficulties for physicians in the uniform application of these adjuvant therapies. Although there are guidelines that evaluate existing studies and provide different levels of evidence for the efficacy of probiotics, they do not offer specific prescribing strategies. The pr...

Prevention, assessment, and identification of drug–drug interactions (DDIs) represent a challenge for healthcare professionals, especially in nosocomial settings. This narrative review aims to provide a thorough assessment of the most clinically significant DDIs for antibiotics used in healthcare-associated infections. Complex poly-pharmaceutical r...

Introduction: Telomeres are nucleoprotein complexes at the ends of chromosomes that are under the control of genetic and environmental triggers. Accelerated telomere shortening is causally implicated in the increasing incidence of diseases. The Mediterranean diet has recently been identified as one that confers protection against diseases. This rev...

This study examines the prospective role of nutraceuticals to be incorporated into One Health perspectives, highlighting the possibility of addressing global multidisciplinary issues such as antibiotic resistance, malnutrition and the increasing prevalence of chronic diseases. The One Health concept addresses the close connection between the health...

Telomeres are part of chromatin structures containing repeated DNA sequences, which function as protective caps at the ends of chromosomes and prevent DNA degradation and recom-bination, thus ensuring the integrity of the genome. While telomere length (TL) can be genetically inherited, TL shortening has been associated with ageing and multiple xeno...

Chitosan is a natural polymer with numerous biomedical applications. The cellular activity of chitosan has been studied in various types of cancer, including melanoma, and indicates that these molecules can open new perspectives on antiproliferative action and anticancer therapy. This study analyzes how different chitosan conformations, such as α-c...

Human immunodeficiency virus (HIV) is a significant global health issue that affects a substantial number of individuals across the globe, with a total of 39 million individuals living with HIV/AIDS. ART has resulted in a reduction in HIV-related mortality. Nevertheless, the issue of medication resistance is a significant obstacle in the management...

It is widely acknowledged that the ketogenic diet (KD) has positive physiological effects as well as therapeutic benefits, particularly in the treatment of chronic diseases. Maintaining nutritional ketosis is of utmost importance in the KD, as it provides numerous health advantages such as an enhanced lipid profile, heightened insulin sensitivity,...

The microbiota–gut–brain axis has received increasing attention in recent years through its bidirectional communication system, governed by the ability of gut microorganisms to generate and regulate a wide range of neurotransmitters in the host body. In this research, we delve into the intricate area of microbial endocrinology by exploring the dyna...

Telomeres are chromatin structures involved in maintaining the integrity of chromosomes. They shorten with each cell division. Although telomere length can be genetically inherited, telomere shortening is directly associated with ageing and the multiple xenobiotics that come into contact with the human body during life. Studies show that certain cl...

In this review, we aim to explore the field of nutrigenetics and its potential impact on obesity, cardiovascular diseases, and diabetes mellitus. Current dietary approaches in nutritional science often overlook the individual’s genetic profile, limiting the effectiveness of personalized diets. Nutrigenetics aims to incorporate genetic data into nut...

The human papillomavirus (HPV) can afflict individuals of both genders. Although HPV is often linked to cervical cancer in females, it is also the primary etiology of various other malignancies, such as anal, penile, and oropharyngeal cancer, that can also impact males. It is of the utmost importance for the male population to possess cognizance re...

By adjusting the synthesis process, silver nanoparticles (AgNp) of various shapes, sizes, and structures can be obtained, all of which have a substantial impact on the biological effect, notably, the regulation of antibacterial activity in the present circumstances of growing bacterial resistance. Due to their relatively small size, nanoparticles m...

The human immunodeficiency virus (HIV) targets the body’s immune system and, if left untreated, may result in acquired immunodeficiency syndrome. (AIDS). HIV’s pathogenesis entails the gradual destruction of CD4+ T cells, which lowers the immune system and leaves the body more susceptible to co-infections and other diseases. HIV has been highlighte...