Miroslav Rozloznik

Hydronaut Project

Objective This implementation project compared standard operating procedures, accepted preventive measures, and disinfection procedures between the initial stage of the COVID-19 pandemic (first wave: March 15 to May 31, 2020) and the later stages of the pandemic (second and third waves: September 1, 2020 to January 31, 2021). Introduction This pro...

One of the major economical expense for health providers in wound care management are patients with diabetic foot ulcer or a chronic lower limb ischemia. Main treatment goal in theese patients is usually reduction in a number of amputations, especially high-ones, deeply affecting quality of life of patients. Hyperbaric medicine is already estabilis...

Introduction: Hyperbaric oxygen treatment (HBOT), based on inhaling pure oxygen under elevated ambient pressure, is used as adjuvant intervention to promote healing in infected wounds. Despite extensive clinical evidence of beneficial effects of HBOT in soft tissue infections the mechanism of action remains to be elucidated. The aim of this study...

The symbiotic relationship between intestinal microbiota and the host is a major mechanism of prevention against the development of chronic and metabolic diseases. The intestinal microbiota provides several physiological functions of the organism from the creation of a natural functional barrier with a subsequent immunostimulatory activity up to af...

The aim of the project was to determine any effect of hyperbaric air on Bacteroides fragilis strains cultivated under hyperbaric conditions. Previously, it was hypothesized that there was a correlation between the presence of Bacteroides bacteria in patients preferring a meaty diet and cancer of the small intestine, and particularly of the large in...

Hyperbaric medicine is a medical specialty, which includes the issue of hyperbaric oxygen therapy and diving medicine. The authors of the article devote attention mainly to hyperbaric oxygen therapy. Theoretical principles are mentioned as well as some important aspects and issues related to scientific evidence benefits of hyperbaric therapy for se...

In the course of therapy with hyperbaric oxygen in multiplace chambers, patients in various countries are accompanied by nursing staff. The nursing and medical activities in the hyperbaric chamber represent a thoroughly unique position in the complex differentiated medical care. It brings about professional, organizational and operating problems an...

Decompression sickness (DCS) in divers is caused by bubbles of inert gas. When DCS occurs, most bubbles can be found in the venous circulation: venous gas emboli (VGE). Bubbles are thought to be stabilized by low molecular weight surfactant reducing the plasma-air surface tension (γ). Proteins may play a role as well. We studied the interrelations...

Vascular gas bubbles are considered the principal element in decompression sickness (DCS) development. Traditionally these bubbles were called VGE (venous gas emboli), however scientific knowledge indicates that similar bubbles may also be present in the arterial circulation, therefore we propose to use “VGE” for “Vascular Gas Emboli”, and we will...

Head up displays (HUD) are beneficial in diving situations when the diver uses both hands for an activity, e.g. photography, scientific work, operating a diver propulsion vehicle or during diver training. They remove the need to locate a submersible pressure gauge or remember to look at a personal dive computer. A new model of HUD, one that can eas...

In the past years, the increased availability of breathing gas mixtures together with progressive development of specialised diving equipment has allowed more divers than ever before to dive beyond traditional recreational dive limits. Such dives are commonly called technical diving and, especially in caves, are often associated with reversed profi...

Purpose: 3D echocardiography (3DE) enables fast 3D acquisition but subsequent manual navigation to find 2D diagnostic planes can be time consuming. We have developed and validated an automated machine learning-based technique to find apical 2-, 3- and 4-chamber (A2C, A3C, A4C) views that enables fast volume navigation and analysis. Methods: 3DE vol...

Introduction: Scuba diving represents stressful event for cardiovascular system. Breathing with compressed air, hyperbaric environment and microbubbles formation are the main factors are the most influencing factors for pulmonary circulation. Hypothesis: The aim of the study was to evaluate the change in morphology and function of the right heart a...

Intermittent prenatal exposure to hypoxia is associated with postnatal alteration in cardiac and endothelial functions. Hyperoxic exposure has significant effects on the cardiovascular system including bradycardia, vasoconstriction and endothelial dysfunction. The impact of intermittent prenatal hypoxia on cardiac rhythm control during mild hyperox...

Measurement of inert gas narcosis and its degree is difficult during operational circumstances, hence the need for a reliable, reproducible and adaptable tool. Although being an indirect measure of brain function, if reliable, critical flicker fusion frequency (CFFF) could address this need and be used for longitudinal studies on cortical arousal i...

Hyperoxia causes oxidative stress. Breath-hold diving is associated with transient hyperoxia followed by hypoxia and a build-up of carbon dioxide (CO₂), chest-wall compression and significant haemodynamic changes. This study analyses variations in plasma oxidative stress markers after a series of repetitive breath-hold dives. Thirteen breath-hold d...

Hallmarks of the mammalian diving response are protective apnea and bradycardia. These cardiorespiratory adaptations can be mimicked by stimulation of the trigeminal ethmoidal nerve (EN5) and reflect oxygen-conserving mechanisms during breath-hold dives. Increasing drive from peripheral chemoreceptors during sustained dives was reported to enhance...

Chemosensory information from peripheral arterial oxygen sensors in the carotid body is relayed by petrosal ganglion neurons to the respiratory networks in the medulla oblongata. Biogenic amines, including histamine, released from glomus (type I) cells of the carotid body are considered to be primary transmitters in hypoxic chemosensitivity. Immuno...

The aim of this study was to enlarge our knowledges about influence of scuba diving on the respiratory system, which is one of the most influenced system during scuba diving. We measured spirometric parameters before and after executed scuba dives by diver with the history of a spontaneous pneumothorax after lung inflammation. In the first experime...

We would like to concentrate on inborn and training and adapted aspects of resting adaptive bradycardia in this article that we measured in the past in the form of basal pulses by high-level basketball player on the level of probably Slovak record (28.min.-1). This value was caused by high trainability that is proved also by test of physiological r...