Miroslav Gasparek

University of Oxford | OX · Department of Engineering Science

The symptomatic full-thickness cartilage lesions or cartilage degeneration leads to the destruction of the normal chondral architecture and bone structure in affected area, causes the osteoarthritis, and general damage to the health. Knee joints are most frequently affected by this condition. The permanent damage of the articular cartilage and subc...

This study aimed to clarify the therapeutic effect and regenerative potential of the novel, amino acids-enriched acellular biocement (CAL) based on calcium phosphate on osteochondral defects in sheep. Eighteen sheep were divided into three groups, the treated group (osteochondral defects filled with a CAL biomaterial), the treated group with a bioc...

The COVID-19 pandemic represents one of the most significant healthcare challenges that humanity faces. We developed a stochastic, individual-based model of transmission of COVID-19 in Slovakia. The proposed model is based on current clinical knowledge of the disease and takes into account the age structure of the population, distribution of the po...

Engineering of a functioning artificial cell has drawn an increasing attention of the synthetic biology community over the last few years. The deletion of the redundant genes from the genomes of the smallest naturally occurring organisms in the effort to find the set of genes essential for life led to the construction of the synthetic organism JCVI...