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Publications (5)
This in vitro preliminary study investigated the attachment of Fusobacterium nucleatum and Porphyromonas gingivalis on titanium alloy healing abutments, which differed in their surface macro-morphology: one was groove-marked while the other was completely smooth. Altogether, twenty implant-healing abutments, ten of each macro-morphology, were evalu...
Objective
Diabetes increases the incidence/severity of periodontal diseases by inducing a chronic inflammation, driven by accumulation of AGEs (advanced glycation end products). We tested whether glycated human serum albumin (G-HSA, a form of AGE), representing a diabetic state, augments the pro-inflammatory response of human gingival fibroblasts (...
The continuous presence of bacteria at the tooth–epithelium or implant–epithelium junction results in a progressive inflammatory process, which leads to the destruction of the gingival connective tissue and subsequently of the alveolar bone, periodontal ligament (PDL) and cementum on the root and/or implant surface. If left undisturbed, this proces...
Background:
Membrane durability is critical for regenerative procedures. We reported previously that type 1-like diabetes in rats accelerates the degradation of collagen membranes and we tested here whether this is associated with increased local production of inflammatory molecules as part of a diabetes-induced chronic inflammation around and wit...
Aim
To examine the in vitro biokinetics of hyaluronic acid (HA) from a collagen membrane (CM) and to evaluate the in vivo effect of immersion of the CM in HA solution on its degradation in streptozotocin (STZ)‐induced diabetes conditions in a rat calvaria subcutaneous model.
Background
CM degradation is accelerated in uncontrolled diabetic rats. I...