Miriam Götte

Miriam Götte
University Hospital Essen | UK Essen · Clinic for Pediatrics III and West German Cancer Centre (WTZ)

PhD

About

43
Publications
5,344
Reads
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542
Citations
Introduction
Miriam Götte currently works at the Clinic for Pediatrics III - Department for Hematology/Oncology and the West German Cancer Centre (WTZ), University Hospital Essen. Her main focus is to implement physical activity and exercise therapy into standard care for cancer patients and survivors. Research is focused on the physiological, psychosocial and biological effects of exercise therapy with a strong expertise in children, adolescents and young adults.
Additional affiliations
April 2014 - present
Universitätsklinikum Münster
Position
  • PostDoc Position
November 2010 - March 2014
Universitätsklinikum Münster
Position
  • Research Assistant

Publications

Publications (43)
Article
Full-text available
The diagnosis of cancer as well as accompanying acute and late effects of treatment are influencing physical activity behavior of patients with childhood cancer and survivors. Research has shown that a pediatric cancer diagnosis is associated with impairments of physical performance, and function, as well as reduced physical, and psychosocial, heal...
Conference Paper
Full-text available
Background/aims: Patients (Pts) with advanced pancreatobiliary cancers (aPBC) frequently suffer from high symptom burden. Studies of curative treatments indicate that exercise can reduce treatment side effects and improve patient-related outcomes (PROMs). However, evidence from prospective studies in the palliative settings is rare. The primary aim...
Article
Full-text available
Objective: Cancer diagnosis, treatment side effects and physical inactivity can lead to reduced muscle strength. Patients undergoing acute treatment experience many burdens that can restrict their mobility and autonomy, leading to limited independence and loss of resources to cope with everyday tasks. In this work, we analyse the status quo and po...
Preprint
BACKGROUND The Physical Activity in Childhood Cancer Survivors (PACCS) study consists of four work packages (WPs) aiming for objective determination of PA, and self-reported health behaviour, fatigue and quality of life (QoL) (WP 1), physical fitness (WP 2), evaluation of barriers/facilitators to PA (WP 1 and 3) and the feasibility testing of an in...
Article
Background: Survivors of childhood cancer represent a growing population with a long life expectancy but high risks of treatment-induced morbidity and premature mortality. Regular physical activity (PA) may improve their long-term health; however, high-quality empirical knowledge is sparse. Objective: The Physical Activity and Fitness in Childho...
Research
Full-text available
Ziel der Leitlinie ist es, flächendeckend ein qualitätsgesichertes bewegungstherapeutisches Angebot in allen kinderonkologischen Zentren zu ermöglichen, sowie Behandlungsteams, Fachkreise und Familien für eine allgemeine Bewegungsförderung zu sensibilisieren. Die Leitlinie soll dazu beitragen, einen ein- heitlichen Wissensstand im interdisziplinäre...
Article
Full-text available
Background: Pediatric cancer patients are at high risk for life-threatening infections, therapy associated complications and cancer-related side effects. Exercise is a promising tool to support the immune system and reduce inflammation. The primary objective of this systematic review was to evaluate the effects of exercise interventions in pediatri...
Article
Full-text available
Exercise therapy is a common supportive strategy in curative cancer treatment with strong evidence regarding its positive effects on, for example, cancer-related fatigue, health- related quality of life, and physical function. In the field of advanced cancer patients, knowledge about exercise as a useful supportive strategy is missing. The aim of t...
Article
Full-text available
Purpose Physical activity (PA) is recommended to improve advanced cancer patients’ (ACP) physical functioning, fatigue, and quality of life. Yet, little is known about ACPs’ attitude towards PA and its influence on fatigue and depressiveness over a longer period. This prospective, non-interventional cohort study examined ACPs’ fatigue, depression,...
Article
Full-text available
Objectives: Exercise interventions during and after treatment for pediatric cancer are associated with beneficial physical, psychological, and social effects. However, valid data about adverse events (AEs) of such interventions have rarely been evaluated. This retrospective study evaluates AEs that occurred during supervised oncological exercise pr...
Chapter
Schwere Erkrankungen und Bewegung schließen sich nicht grundsätzlich aus. Vielmehr ist es bei Vorliegen einer onkologischen oder hämatologischen Erkrankung ratsam, Kindern und Jugendlichen während aller Therapiephasen sowie in der Nachsorge den Zugang zu Bewegung zu ermöglichen. Dies umfasst allgemeine körperliche Aktivitäten wie auch gezielte spor...
Article
Full-text available
Physical activity (PA) and exercise are safe and beneficial for children and adolescents affected by cancer. Yet, this population is not active enough to receive benefits. PA guideline and recommendation statements can support individual behavior and practice change. The purpose of this project was to develop the international Pediatric Oncology Ex...
Article
Full-text available
Background Research indicates reduced physical performance from diagnosis into survivorship of pediatric cancer patients. However, there is no systematic information or guideline available on the methods to assess physical performance and function in this population. The purpose was to systematically compile and describe assessments of physical per...
Article
Full-text available
The field of pediatric exercise oncology explores the relationships between physical activity (PA), including exercise, and a range of outcomes among children and adolescents affected by cancer. Although PA is safe and beneficial for this population, several important gaps in knowledge and practice remain. In this article, we describe research and...
Chapter
Physical inactivity additionally increases the burden of cancer therapy and the probability of late effects in children, adolescents and young adults during and after cancer treatment. Exercise programs should be provided for all children from acute treatment to long-term aftercare to improve their physical and psychosocial condition. The Network A...
Article
Background While the prognosis of patients with Ewing sarcoma (EwS) is improving, little is known about the frequency of pain and its risk factors in survivors of EwS. This study aims to analyse the prevalence and risk factors of pain and its predictive value for recurrence. Patients and Methods In patients with remission after treatment of EwS, f...
Article
Full-text available
Background: In order to counteract fatigue, physical activity (PA) is recommended for all stages of cancer. However, only few advanced cancer patients (ACP) are physically active. Quantitative data with high numbers of ACP reporting barriers to PA are missing. This study aimed to identify barriers to PA in ACP with tiredness/weakness and investiga...
Article
Full-text available
Objectives Supervised exercise interventions during inpatient care are feasible. The objective was to evaluate the usability of activity trackers and centralised monitoring to conduct a home-based exercise intervention during cancer treatment. The primary endpoint and confirmatory analysis was achievement of individual goals for daily steps, compar...
Article
Full-text available
Background: Our objective was to determine whether, compared with control interventions, pharmacologic interventions reduce the severity of fatigue in patients with cancer or recipients of hematopoietic stem-cell transplantation (hsct). Methods: For a systematic review, we searched medline, embase, the Cochrane Central Register of Controlled Tri...
Article
Fatigue is a prevalent and distressing symptom in children and adolescents with cancer and in those who have undergone haemopoietic stem-cell transplantation. A multidisciplinary and multinational group of experts in paediatric oncology and fatigue, together with patient advocates, developed a clinical practice guideline for management of fatigue o...
Article
Purpose: Objective was to determine whether physical activity reduces the severity of fatigue in patients with cancer or hematopoietic stem cell transplant (HSCT) recipients. Methods: We conducted a meta-analysis of randomized trials comparing physical activity with control interventions for the management of fatigue in patients with cancer or H...
Article
Purpose To determine whether non-physical activity mind and body practices reduce the severity of fatigue in patients with cancer or hematopoietic stem cell transplant (HSCT) recipients compared to control interventions. Methods We included randomized trials which compared non-physical activity mind and body practices compared with control interve...
Article
Full-text available
Objective Existing research recognizes low levels of physical activity in pediatric patients with cancer, but much uncertainty exists about their capability to self-reflect physical activity levels. The objective of this study was to compare results of subjective self-reports and objective accelerometers regarding levels of daily walking as well as...
Article
Die weitreichenden Potenziale individualisierter Bewegungsforderung fur krebskranke Kinder und Jugendliche sollten uber den gesamten Zeitraum der Akuttherapie, in der Nachsorge und bei der Ruckkehr in den Alltag genutzt und als Bestandteil der Normalitat aufrechterhalten und gefordert werden. Dieser Artikel stellt beispielhaft fur den Standort Muns...
Article
Resumption of physical activity and reintegration into social surroundings after treatment for pediatric cancer is of high importance to recover from the burden of disease and treatment and to positively influence long-term health outcomes. Eighty-three children who had completed intensive treatment for pediatric cancer were surveyed regarding thei...
Article
Reduced motor performance can negatively affect physical activity and social partake after childhood cancer. Especially in bone tumor patients, who are at risk of physical limitations due to surgical interventions, motor performance has not yet been sufficiently investigated. Therefore, this study aimed at assessing motor performance in pediatric b...
Article
Zusammenfassung Während einer Krebserkrankung sind die betroffenen Kinder und Jugendlichen für lange Zeit körperlich inaktiv. Im Sinne einer frühzeitigen Bewegungsförderung wird schon während der Akuttherapie ein individualisiertes, angepasstes Sportprogramm empfohlen. Die Inhalte orientieren sich dabei an der jeweiligen Sportanamnese, den persönl...
Conference Paper
Introduction Reduced physical activity levels in children with cancer (Winter et al. 2009) additionally increase the cancer-related burden and presumably lead to further persisting problems like reduced motor performance (Götte et al. 2015). Objectives The first objective was to evaluate the current need of exercise interventions by comparing intr...
Article
Reduced motor performance may particularly limit reintegration into normal life after cessation of treatment in pediatric cancer patients. This study aimed at analyzing motor performance at the end of the acute treatment phase and reveals potential risk factors for motor deficits. A childhood cancer population with different tumor entities was asse...
Article
Background Due to growing evidence about the value of exercise in pediatric cancer patients, the purpose of this study was to determine factors that influence participation in physical activities and exercise in children and adolescents during treatment.ProcedureThis cross-sectional qualitative study included 40 pediatric cancer patients during int...
Article
Physical activities are important for the development of children and increasing evidence suggests beneficial effects of physical activity promotion during cancer treatment as well. The present study aimed at evaluating the current need of exercise interventions in pediatric cancer patients undergoing acute treatment and identifying risk factors fo...
Article
Malignant disease and anticancer therapy dramatically affect daily life activities and participation in grassroots and high-performance sports. Specifically in childhood and adolescence such activities are relevant factors of individual development and social life. This review focuses on the inherent reduction of normal physical activity in pediatr...
Conference Paper
Objective Due to growing evidence about the value of exercise in pediatric cancer patients, the purpose of this study was to determine barriers and motivations for physical activities during treatment. Methods This qualitative study included semi-structured guideline interviews, transcription and coding based on grounded theory with 40 pediatric ca...
Article
Background: Pediatric cancer patients suffer from various negative consequences due to the disease, the medical therapy and the inactivity during the intensive treatment. Only few studies have systematically identified the adverse effects of cancer on motor performance in childhood. Methods: To determine the motor performance of pediatric cancer...
Conference Paper
Background Exercise programs are hardly integrated into the inpatient treatment of pediatric cancer patients, and physical activity (PA) is considerably reduced [1]. To fulfill the right of PA promotion and to practice secondary prevention, it seems to be useful integrating PA already during acute treatment. This project aimed at analyzing the barr...
Conference Paper
Introduction The haematopoietic stem cell transplantation (HSCT) is associated with severe physical and psychological side effects, such as muscle atrophy, loss of physical fitness and other consequences of immobility. Since some studies have shown positive effects of physical activity during the inpatient stay for HSCT , this study focused on exam...

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