Minoo Shaddel

Background: Fasciolosis is a global parasitic disease caused by liver trematodes such as Fasciola hepatica, affecting various mammals, including sheep, goats, cattle, pigs, and humans worldwide. Cathepsin L (Cat L) found in the life stages of F. gigantica is associated with the pathology of the fluke. Given the detrimental impact of fasciolosis on...

The Internet of Things is an emerging and growing phenomenon that is rapidly spreading around the world, according to global statistics. The connection of a variety of physical objects to the internet and access to wireless sensor data is called the internet of things, whose achievement is to control the physical world around us. The Internet of Th...

Objective: Parasitic diseases have created numerous health and economic problems in developing and developed countries. One of the most prevalent ways of transmitting diseases is by consuming raw vegetables that are contaminated with parasites. With respect to the importance of healthy vegetable consumption, an awareness of vegetable status helps...

The antileishmanial activity of Aloe vera leaf exudates: in vitro and in vivo Background: According to the drug resistance and side effects of the standard treatments for leishmaniasis, achieving effective treatment with less side effects and more benefits is of paramount importance. The present study aimed to evaluate the effect of Aloe vera leaf...

Leishmaniasis is an important tropical cutaneous disease that is endemic in the Middle East, including Iran. There is no consensus on the appropriate therapeutic method, dose, and duration for this disease. The pentavalent antimonial compounds are the first-line treatments of leishmaniasis. With regard to the resistance of this disease against drug...

Hydatid disease is an economic and public health concern in many countries. Currently, surgery is the main treatment option for hydatid disease. In the surgical treatment of hydatidosis, the use of scolicidal agents is very important due to inactivating live protoscoleces and preventing the recurrence of infection. Therefore, it is necessary to inv...

In the present study, a total of 615 fecal samples from veterinary clinics were screened by microscopy for the presence of Cryptosporidium and Giardia oocysts. Molecular genotyping of Cryptosporidium and Giardia were carried out using PCR and sequence analysis. Overall, Cryptosporidium and Giardia oocysts were detected in the 0.6% (2/315) and 1.9%...

Background & Objective: Skin ulcers and their slow healing are considered as one of the important medical aspects. Nowadays, various antibiotics and materials are used to accelerate the wound healing process. One of the methods taken in the field of wound healing is using ozone. On the other hand, one of the factors that hurt the speed of wound hea...

Background Leishmania donovani, a parasitic protozoan causing visceral leishmaniasis, can lead to a dangerous and often fatal disease in humans. Current treatment for leishmaniasis may have severe side effects, low efficacy and high cost, hence an immediate need for new efficient drugs is essential. Arabinono-1, 4-lactone oxidase enzyme from Leishm...

Background and Aim: Visceral leishmaniasis, a native disease in developing countries, can cause functional impairment in various organs, including the reproductive system, which can lead to infertility. The aim of this study was to evaluate the stereological, morphometric and morphological changes of testicular histoarchitecture in an experimental...

Aims Aloe Vera is among the crucial medicinal plants, with proven anti-cancer effects. This study aimed to investigate the effect of plant extracts of Aloe Vera Leaf (AVL) on the proliferation of cell lines K562 (erythroleukemia) and Peripheral Blood Mononuclear Cells (PBMCs). Methods & Materials The inner parts of the plant, including the gelatino...

The authors have retracted this article [1] because it has been previously published [2].

Toxoplasma gondii, is a causative agent of morbidity and mortality in immunocompromised and congenitally-infected individuals. Attempts to construct DNA vaccines against T. gondii using surface proteins are increasing. The dense granule antigens are highly expressed in the acute and chronic phases of T. gondii infection and considered as suitable D...

Background & objectives: Leishmania parasites are sensitive to very low temperature. Cryotherapy is considered as an alternative to the existing pentavalent antimonials, for local treatment of cutaneous leishmaniasis (CL). Normally, liquid nitrogen (N2) at a temperature of -196 °C, is used in cryotherapy of CL, but it's efficacy is not consistent....

Giardia lamblia causes malabsorption. The aim of this study was to evaluate serum and saliva calcium and magnesium levels in patients with giardiasis. Thirty patients with giardiasis as a case and 30 person without giardiasis as a control group were enrolled. The stimulated and unstimulated whole saliva and serum calcium and magnesium levels were a...

Introduction: α-amylase is a major form of amylase found in humans and other mammals. It is the special key enzyme involved in carbohydrates breakdown. Inhibition of this enzyme could be used in treatment of diabetes. In this study, the effect of ten Iranian macrolichens on alpha amylase were tested. Methods: Different concentrations of the extract...

Background: Despite the wide diversity of the basic growth forms (crustose, squamulose, foliose, and fruticose), all lichens have a similar internal morphology. The bulk of the lichen's body is formed from filaments of the fungal partner, and the relative density of these filaments defines the layers within the lichen.

Regarding fast development of the nanotechnology and the probably of it's side effects on aquatic body organs, this study investigate the effects of nanosilver administration on histology of gill, kidney and biochemical parameters in common carp. The silver nanoparticles were synthesized in a one-step reduction process in an aqueous solution. 60 O....

The aim of the present study was to determine the effects of Toxoplasma gondii (T. gondii) infection on anxiety, depression and ghrelin level in male rats. Twenty four male rats were assessed in two equal groups. T. gondii tachyzoite (ip) were injected in infected group and control group received (2 ml) physiological serum (ip). Elevated plus Maze...

Background The prevalence of toxoplasma gondii (T.g) infection in blood donors has been poorly studied. The aim of this study was to assess the prevalence of acute and chronic toxoplasmosis in blood products. Methods A total of 223 blood products (101 fresh frozen plasma (FFP) and 122 packed cells (PC)) in Imam Reza hospital blood bank, Tehran, Ir...

Context: Toxoplasmosis is one of the most common parasitic infections worldwide and is occasionally able to cause cysts in the central nervous system (CNS). Although its importance is highlighted in immune-compromised patients, it is also associated with non-identified complications due to various anatomopathological and histological changes in CNS...

The prevalence of Toxoplasma gondii infection in the blood donors has been poorly studied. The aim of this study was to assess the prevalence of acute and chronic toxoplasmosis in blood products. A total of 250 blood products (112 fresh frozen plasma and 138 packed cells) in the Blood Transfusion Institute, Shiraz, Iran were tested for specific T....

Background: Leishmania major p4 gene is localized in the endoplasmic reticulum at the intracellular amastigote stage. Objectives: We expressed this gene for possible future vaccine preparation, drug target studies, and leishmaniasis serodiagnosis test. Materials and Methods: The Leishmania major (MRHO/IR/75/ER) p4 gene, which had been subcloned int...

Received: 15/Dec/2007, Accepted: 2/Apr/2008 Objective: Leishmania major P4 gene is normally expressed during amastigote form of the parasite and can be good candidate for producing an effective vaccine. In this study we cloned this gene in suitable vector (pQE-30) for further vaccine preparation studies. Materials and Methods: Leishmania promastigo...

Purpose: To introduce the importance and world prevalence of ocular leishmaniasis (OL), its clinical manifestations, and diagnostic and management features with more emphasis on Iranian cases. Methods: We reviewed all available articles published about OL during recent 50 years. Results: OL is an ocular protozoal infection which is widespread in th...