Minoo Dabiri

• PhD
• Professor at Shahid Beheshti University

A new aminonitrile-functionalized Fe3O4 has been synthesized via the Strecker reaction, the designed aminonitrile ligand on the surface of the magnetic core coordinated to copper(II) to obtain the final new catalyst. The fabricated nanocatalyst was characterized by Fourier transform Infrared (FT-IR), Field Emission Scanning Electron Microscopy (FES...

Fe3O4@nitrogen-doped carbon core-double shell nanotubes (Fe3O4@N-C C-DSNTs) were successfully synthesized and applied as a novel nanosorbent in ultrasonic assisted dispersive magnetic solid phase extraction (UA-DMSPE) of tribenuron-methyl, fenpyroximate, and iprodione. Subsequently, corona discharge ion mobility spectrometry (CD-IMS) was employed f...

Palladium nanoparticles anchored to the core-double shell magnetic nitrogen-doped carbon (Fe3O4@N-C) nanotubes have been successfully synthesized and characterized. It is possible to load palladium nanoparticles inside and outside of the nanotube. The catalytic performance of the as-prepared nanohybrids was evaluated by the one-pot synthesis of the...

Aiming to achieve enhanced catalytic activity and stability toward the reduction of nitroarenes and the oxidation of benzyl alcohols, was synthesized novel core-shell nanostructures of graphene wrapped Fe3O4@polydopamine (PDA)/Pd octahedral. Different graphene-based materials such as graphene oxide (GO), and nitrogen doped reduced graphene oxide (N...

The 2-phenylphthalazinone derivatives are the main skeleton of various pharmaceuticals. In this work, an efficient method for the regioselective Ru(II)-organometallic complex-catalyzed alkenylation of 2-phenylphthalazinone through N-directing group via C–H activation process is presented. The results have proved to be satisfactory for a wide range...

For its unique role in developing and designing new bioactive materials and healthcare products, fluoro-organic compounds have attracted remarkable interest. Along with ever-increasing demand for a wider availability of fluorine-containing structural units, a large diversity of methods has been introduced to incorporate fluorine atoms specially in...

Pd nanoparticle‑nitrogen doped reduced graphene oxide (Pd/N-RGO) nanohybrid was successfully utilized for the C-H-acyloxylation of N-arylcarbamates and the CH halogenation of quinazolinones with N-halosuccinimides. The use of the catalyst was shown to be a highly efficient, less time-consuming and recyclable procedure for two different types of CH...

An effective and recyclable catalyst based on tungstate ion immobilization on magnetic ionic liquid modified graphene oxide (WO4@Fe3O4/GO-IL) has been synthesized in this research. The catalyst was characterized by various techniques such as Raman spectroscopy, X-ray diffraction, thermogravimetric analysis, electron microscopy transmission and scan...

Copper-nitrogen catalyst was synthesized by the direct carbonization of the copper complex on the zeolitic imidazolate framework (ZIF-8). The catalytic activity of the carbonized material was evaluated by the synthesis of propargylamines via the A3 coupling reaction of aldehydes, arylacetylene, and secondary amines under the solvent-free (SV) condi...

Ruthenium nanoparticles on nitrogen and sulfur-doped three-dimensional graphene (Ru@NSG) nanohybrid were prepared via a one-pot hydrothermal method with graphene oxide (GO) and RuCl3 as the raw materials and thiourea as a reducing-doping agent for the first time. The catalytic activity of nanohybrid was evaluated by the reduction of nitroarenes to...

In this article, a FeOx@nitrogen doped carbon (FeOx@N–C) core–shell cubic nanostructure has been successfully synthesized by the carbonization of ZIF-8 coated Fe2O3 cubes. Finally, FeOx@N–C was successfully decorated with palladium nanoparticles (Pd NPs) in a facile route by reducing H2PdCl4 in the presence of sodium borohydride as a chemical reduc...

Pd nanoparticles decorated on cubic shaped ZIF-based materials have been successfully prepared. The nanocomposites have been characterized by X-ray diffraction, field emission scanning electron microscopy, N2 sorption analysis, and transmission electron microscopy. The catalytic activities of synthesized materials were evaluated in Suzuki-Miyaura c...

Copper oxide (I) nanoparticles decorated on nitrogen-doped carbon (N-C) rod-shaped core-shell nanostructure have been successfully prepared. The nanostructures have been developed by the reduction of Cu²⁺ with ascorbic acid over Fe3O4@N-C rod-shaped core-shell nanostructure followed by aerobic oxidation of copper nanoparticles. Furthermore, the pho...

This review exhibits the role of orthoesters as versatile precursors in synthetic methodologies, which provide access to wide range of compounds with pharmaceutical, agrochemical values. Moreover, highlight studies demonstrating the contribution of orthoesters in inducing stereoselectivity in certain reactions have been reported. In light of the re...

A new ultrasonic-assisted dispersive solid-phase extraction method using mesoporous nanosorbent composed of silica, graphene, and palladium (II) (M S/G@-SH@Pd (II)), coupled with corona discharge ion mobility spectrometry, was developed for trace determination of organophosphorus pesticides. Initially, the M S/G@-SH@Pd (II) nanosorbent was synthesi...

The regio‐ and chemo‐selective Pd‐catalyzed C–H activation methods have been successfully reported for directed C–H sulfonation and halogenation of pyridazinedione with arylsulfonyl chlorides and N‐halosuccinimide, respectively. These protocols are compatible with a range of various functional groups and exhibit excellent regio‐selectivity under mi...

AuPd alloy nanoparticles (NPs) immobilized on graphitic carbon nitride sheets (AuPd/g-C3N4) were used as an effective the Mott−Schottky-type photocatalyst for the visible-light-enhanced Suzuki–Miyaura cross-coupling (SMC) reaction at room temperature. The Mott-Schottky-type photocatalyst in the coupling of IB and PBA displayed the high turnover fre...

The palladium‐catalyzed cross‐dehydrogenative coupling (CDC) followed by an intramolecular cyclization between arylquinazolinones and aldehydes has been described. This viable transformation provides a variety of novel substituted hydroxyisoindolo[1,2‐b]quinazolinone compounds in moderate to good yields. Additionally, the reaction is performed with...

For the first time, a novel sandwich structure of graphene-periodic mesoporous silica (G-PMS) sorbent was introduced for the removal of acid blue (as a model analyte) from wastewater samples. Moreover, this procedure was investigated through static and column modes. The effect of different key factors affecting the adsorption of the target compound...

Ruthenium (Ru) nanoparticles (NPs) are supported on nitrogen-doped carbon (N-C) derived from bimetallic zeolitic imidazolate framework (BMZIF) for the first time. [email protected] is prepared by the direct carbonization of the Ru ³⁺ encapsulated inside BMZIF. The photocatalytic activity of the carbonized material was evaluated by the selective oxid...

An efficient and straightforward protocol for the regioselective acyloxylation and oxidative homocoupling of N‐arylarbamates via Pd‐catalyzed C−H bond activation was demonstrated. This protocol has given acyloxylation and homocoupled products in generally moderate to good yields. Also, this protocol was convenient, efficient, and applicable to vari...

An ultrasound-assisted method is described for dispersive solid phase extraction of trace levels of triazole fungicides. A sorbent was prepared from an N-heterocyclic carbene copper complex that was supported on ionic liquid-modified graphene oxide. The sorbent was characterized by scanning electron microscopy, transmission electron microscopy, Ram...

A novel method for the palladium‐catalyzed decarboxylative ortho C–H bond arylation of pyridine 1‐oxides and anilides with benzoic acids as aryl sources is described. The established methodology provides a direct approach for the synthesis of 2‐arylpyridine 1‐oxides and 2‐aryl anilides in good isolated yields.

The preparation of palladium nanoparticles (Pd NPs) supported on Fe3O4@nitrogen doped carbon (N-C) core-shell (C-S) and yolk–shell (Y-S) nanostructures is reported. The Fe3O4@N[email protected] C-S nanostructures were synthesized by two different methods. The first method included two steps: (i) the annealing treatment of the Fe2O3@polydopamine (PD...

A N-heterocyclic carbene–copper complex grafted on graphene oxide with an ionic liquid framework was prepared. The synthesis of (i) 1,2,3-triazole derivatives by ‘Click reaction’ and (ii) propargylamine derivatives by ‘A³ coupling reaction’ in aqueous media by this new catalyst were all successfully accomplished. The catalyst is characterized using...

Mesoporous silica/graphene (KIT‐6/G) with pendent 3‐mercaptopropyl groups has been prepared by condensation of surface silanols and (3‐mercaptopropyl)trimethoxysilane (MPTMS). Treatment of the mercaptopropylated with Pd(CH3CN)2Cl2 gave a heterogeneous Pd‐catalyst (Pd@KIT‐6/G‐SH). The catalytic activity of the catalyst was investigated in two types...

A convenient synthetic pathway for 14 C labeling of fentanyl [N-(1-phenethyl-4-piperidinyl)-propionanilide], a widely used narcotic analgesic agent, with good radiochemical yield was developed.

Gold nanoparticles were decorated onto sulfonated three-dimensional graphene (3DG-SO3H) through spontaneous chemical reduction of HAuCl4 by 3DG-SO3H. This nanocomposite exhibited excellent catalytic activity for the synthesis of symmetric biaryls via the Ullmann homocoupling of aryl iodides in an aqueous medium. Additionally, this nanocomposite was...

Novel substituted amino acid tethered norsufentanil derivatives were synthesized by the four-component Ugi reaction. Norsufentanil was reacted with succinic anhydride to produce the corresponding carboxylic acid. The resulting carboxylic acid has undergone a multicomponent reaction with different aldehydes, amines, and isocyanides to produce a libr...

A novel nitrogen doped carbon photocatalyst was successfully prepared from the carbonization of copper phthalocyanine (CuPc) on/in zeolitic imidazolate framework-8 (ZIF-8) hybrid. Carbonized catalysts derived from either ZIF-8 or CuPc exhibit poor activity towards the degradation of dyes (such as methyl orange (MO) and Rhodamine B (Rh B)), whereas...

Cu nanoparticles with average particles size around 10 nm were incorporated on the surface of a mesoporous carbon nitride support. The XRD and N2 adsorption isotherms show that it maintains a hexagonal mesoporous structure with a high surface area (600.03 m2 g−1). The embedded Cu nanoparticles exhibit extremely high catalytic performance in two dif...

A Pd-catalyzed ortho-selective halogenation of benzoxazinone and quinazolinone scaffolds has been described employing N-halosuccinimide as both a halogen source and an oxidant reagent via C-H bond activation. This transformation shows high chemo- and regioselectivities and demonstrates a broad range of benzoxazinone and quinazolinone substrates wit...

An efficient and straightforward method for the synthesis of new 5,5′-(2-benzylidenemalonyl)bis(2,2-dimethyl-1,3-dioxane-4,6-dione) derivatives by the reaction of Meldrum’s acid and aldehydes under mild reaction conditions is reported. Furthermore, the leaving group potency of Meldrum’s acid molecules toward the synthesis of 3,4-dihydro-2H-benzo[g]...

Magnetic core double-shelled carbon with Fe3O4 nanoparticles as the core, reduced graphene oxide (RGO) as the inner shell and carbon (C) layer as the outer shell, have been successfully designed and prepared. This tailor-making structure acts as an excellent capsule for encapsulating Au nanoparticles (Au NPs), which could effectively prevent Au NPs...

PdCo bimetallic nanoparticles (NPs) were decorated over three-dimensional graphene (3DG) in a facile manner by reducing palladium chloride and cobalt chloride in the presence of ethylene glycol as reducing, stabilizing and dispersing agent. The PdCo NPs–3DG nanocomposite was characterized using Raman, X-ray photoelectron and energy-dispersive X-ray...

A copper nanoparticle decorated three-dimensional graphene nanocomposite was prepared at room temperature by reduction of copper sulfate using l-ascorbic acid as the reducing agent. The synthesized Cu NPs-3D G nanocatalyst exhibited excellent catalytic activity in the synthesis of 1,2,3-triazoles.

A vanadium Schiff base complex on nano silica was prepared by reaction of nano silica NH2-functionalized, 2,4-dihydroxy benzaldehyde and VO(acac)2. The VSBC@NS was used as an efficient and reusable heterogeneous catalyst for the selective oxidation of sulfides to sulfoxides and alcohols to aldehydes with H2O2 as an oxidant in methanol. Graphical ab...

An efficient multi-component synthesis of indazolophthalazine derivatives through the reaction of phthalhydrazide, 2-hydroxynaphthalene-1,4-dione or 2,5-dihydroxycyclohexa-2,5-diene-1,4-dione and active carbonyl compounds under ultrasonic irradiation is reported. This chemistry provides an efficient and promising synthetic strategy to diversity-ori...

Abstract 3-Alkyl-6-amino-1,4-dihydro-4-{[(1,2,3-triazol-4-yl)methoxy]phenyl}pyrano[2,3-c]pyrazole-5-carbonitrile derivatives were synthesized through a one-pot five-component condensation reaction.

The ultra-small Au nanoparticles (Au NPs) immobilized HS-functionalized sandwich-like periodic mesoporous silica (PMS) coated graphene (G) to form a novel nanocomposite catalyst Au NPs@HS-G-PMS. The synthesized Au NPs@HS-G-PMS nanocatalyst exhibited excellent catalytic activity on the three kinds of organic reactions. The reduction of 4-nitrophenol...

Palladium nanoparticle are decorated over a highly nitrogen-doped graphene (Pd NPs-HNG) in a facile manner by reducing palladium chloride in the presence of ethylene glycol as reducing, stabilizing, and dispersing agent. The obtained catalyst can act as an efficient catalyst for the Suzuki–Miyaura and Ullmann-type coupling reactions of a broad spec...

The synthesis of pyrano[2,3-c]pyrazole derivatives has been described by regio- and chemoselective four-component reaction of a dialkyl 3-oxopentanedioate, an active carbonyl compound, hydrazine and malononitrile in water/ethanol as a green medium under catalyst-free condition.

Au nanoparticle-reduced graphene oxide nanocomposite is found to be an efficient and reusable catalyst for the Ullmann homocoupling of aryl iodides.

A novel gold nanoparticle supported on graphene oxide with ionic liquid framework (Au@GO-IL) was shown to be a highly active and recyclable catalyst for novel domino oxidative A3 coupling reaction that has been successfully developed with benzyl alcohols instead of their corresponding aldehydes in aqueous media.

The water-dispersible sulfonated graphene (s-G) was synthesized by anchoring the sulfonic acid groups on graphene sheets. Subsequently, the magnetic separable Fe3O4/s-G was synthesized from the Fe3O4 nanoparticles decorated on s-G sheets by the co-precipitation method of iron ions. Finally, Fe3O4/s-G was successfully decorated with gold nanoparticl...

(1,2,3-Triazol-4-yl)methyl-3-amino-5,10-dihydro-5,10-dioxo-1H-pyrazolo[1,2-b]phthalazine-2-carboxylate derivatives were synthesized by a four-component, one-pot condensation reaction of benzaldehyde derivatives, an active methylene compound (prop-2-ynyl-2-cyanoacetate), azides, and phthalhydrazide in the presence of Cu(OAc)2/sodium ascorbate as cat...

Core-shell Cu@Cu2O nanoparticles on reduced graphene oxide (Cu@Cu2O NPs-RGO) nanocomposite were prepared at room temperature by in situ reduction of graphene oxide (GO) and copper sulfate using L-ascorbic acid as reducing agent then air oxidation surface of copper nanoparticle. The Cu@Cu2O NPs–RGO nanocomposite are characterized by infrared spectro...

The synthesis of some tetrahydropyrazolopyridine derivatives has been described by a one-pot 2A + 2B + C + D four component reaction of a 1,3-dicarbonyl compound, an aldehyde, hydrazine and ammonium acetate in ethanol as a green media under catalyst-free condition.

A simple and efficient one-pot four-component procedure has been developed for the synthesis of a wide range of compounds containing the (triazolyl)methyl oxo-pyrimidine-carboxylate system from propargyl β-keto esters, various azides, aldehydes, and urea in the presence of catalytic amounts of (AcO)2Cu/sodium ascorbate in AcOH. The method worked we...

Silica-supported terpyridine palladium(II) was prepared and used as an effective and recyclable catalyst in Mizoroki–Heck and Suzuki–Miyaura coupling reactions. The catalyst was very effective for the Mizoroki–Heck reaction of aryl halides with olefins and conversion was in most cases excellent. The catalyst showed good thermal stability (up to 230...

A practical and efficient method for the synthesis of 1,2,3-triazoles via the cycloaddition reaction of azides and CH-acids in the presence of 1,1,3,3-tetramethylguanidine (TMG) in ethanol at 30 °C has been reported. The simple experimental procedure, short reaction times, and good yields are the advantages of the present method.

A new and efficient approach for the synthesis of 2,4,5-triaryl-1H-imidazoles linked 1,4-disubstitued 1,2,3-triazoles have been developed by multicomponent condensation with Huisgen 1,3-dipolar cycloaddition. A mixture of aromatic propargylated aldehydes, different azides, benzil, and ammonium acetate were condensed in the presence of catalytic amo...

Highly efficient one-pot reactions of benzil or benzoin, ammonium acetate, and aliphatic or aromatic aldehydes were carried out in water in the presence of 1-methylimidazolium trifluoroacetate ([Hmim]TFA) under mild and green conditions. This approach can be useful for the three-component synthesis of 2-alkyl- and 2-aryl-4,5-diphenyl-1H-imidazoles...

Steam distilled volatile oil from leaves of Pelargonium roseum R.Br. was analyzed by GC and GC-MS. Thirty-two compounds were identified; the major compounds were citronellol (27.3 %), citronellyl formate (17.2 %), β-caryophllene (10.3 %), γ-muurolene (6.1 %) and menthone (5.0 %).

An efficient one-pot four-component protocol for the synthesis of imidazo[1,2-a]pyridines was developed by condensing ethane-1,2-diamine (2), 1,1-bis(methylthio)-2-nitroethene (1), aldehydes 3, and activated methylene compounds in EtOH under reflux conditions (Tables 1–3). The features of this procedure are operational simplicity, good yields of pr...

A novel straightforward synthesis of 3-(1H-tetrazol-5-yl)coumarins (=3-(1H-tetrazol-5-yl)-2H-1-benzopyran-2-ones) 6 via domino Knoevenagel condensation, Pinner reaction, and 1,3-dipolar cycloaddition of substituted salicylaldehydes (=2-hydroxybenzaldehydes), malononitrile (propanedinitrile), and sodium azide in H2O is reported (Scheme 1 and Table 2...

A novel one-pot three-component reaction for the synthesis of novel 1,2,3-triazol-4-yl-methylthio-3-arylquinazolin-4(3H)-one derivatives by using the Huisgen 1,3-dipolar cycloaddition reaction of organic azides andin situ prepared terminal alkynes in good to excellent yields is reported.

A one-pot procedure has been developed for the synthesis of (1,2,3-triazolyl) methoxyphenyl tetrahydro-5-oxo-4H-chromene derivatives by concurrent reaction of aryl oxypropargylated aldehydes, various azides, active methylene compounds, and 1,3-cyclohexanediones using catalytic amounts of Cu(OAc)2/ sodium ascorbate and diammonium hydrogen phosphate...

A series of triazolyl methoxyphenyl 1,8-dioxo-decahydroacridine derivatives has been prepared in a one-pot, pseudo-five-component reaction of aromatic propargylated aldehydes, various azides, dimedone, and a variety of amines in the presence of Cu(OAc)2/sodium ascorbate and 1-methylimidazolium trifluoroacetate ([Hmim]TFA) as the catalyst in good yi...

A practical, simple, and efficient method for the synthesis of pyrano-fused spirooxindoles via an organocatalytic three-component reaction of isatins, malononitrile, and dialkyl acetylenedicarboxylate in the presence of 3,4-dimethylaniline as an organocatalyst in ethanol is reported. The structures of these products are confirmed by IR, 1H NMR and...

Abstract An efficient and simple synthesis of spiro[11H-benzo[g]pyrazolo[4,3-b]quinoline-11,3′-[3H]indole]-2′,5,10(1′H)-triones and spiro[acenaphthylene-1(2H),11′-[11H]benzo[g]pyrazolo[4,3-b]quinoline]-2,5′,10′-triones by a three-component condensation reaction of 2-hydroxy-1,4-naphthoquinone, pyrazol-5-amines, and isatins or acenaphthylene-1,2-dio...

Abstract 1-Methylimidazolium trifluoroacetate ([Hmim]TFA) is reported as a cost-effective catalyst for a simple and environmentally benign hetero-Michael reaction. [Hmim]TFA works both as reaction medium and catalyst. The reaction is applicable to various aromatic sulfur and nitrogen nucleophiles. This method has advantages such as high yields, sho...

An approach for the synthesis of new 5-substituted-tetrazoles via multi-component domino Knoevenagel condensation/1,3 dipolar cycloaddition reaction of carbonyl compounds, malononitrile and sodium azide in water without assistance of any catalyst has been reported. This general protocol provides a wide variety of 5-substituted 1H-tetrazoles in good...

The 1-{[(1H-1,2,3-Triazol-4-yl)methoxy]phenyl}-1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives 5 were synthesized by a simple and efficient method, i.e., by the four-component, one-pot condensation reaction of phthalohydrazide 4, a (propargyloxy)benzaldehyde 1, an active methylene compound 3 (malononitrile or ethyl cyanoacetate), and an azide...

[(1,2,3-Triazol-4-yl)methoxy-phenyl]-2H-indazolo[2,1-b]phthalazine-trione derivatives were synthesized in a simple and efficient method from the one-pot four-component condensation reaction of phthalhydrazide, aromatic propargyloxy aldehydes, active methylene compounds (dimedone and 1,3-cyclohexanedione), and azides in the presence of Cu(OAc)(2)/so...

ZnO-nanoparticles, as a recyclable heterogeneous catalyst, efficiently promoted the one-pot three-component Mannich reaction of ketones, aromatic aldehydes and amines in water to afford the corresponding beta-amino carbonyl compounds in good to excellent yields and with moderate diastereoselectivity. The method offers a new modification of the Mann...

We have been studying the development of new asymmetric two-center catalysis using rare earth alkoxides and bifunctional sugar and related ligands. In The Fourth International Conference on Multi-Component Reactions and Related Chemistry (MCR 2009), new catalytic asymmetric reactions using catalysts 1 and 2 and catalytic asymmetric syntheses of ran...

We have developed a clean, simple and efficient method for the synthesis of spiro compounds by three-component reaction of isatins (=1H-indole-2,3-diones) or acenaphthylene-1,2-dione, 1,3-diphenyl-1H-pyrazoles-5-amines, and tetronic acid (=furan-2,4-(3H,5H)-dione or 2-hydroxy-1,4-naphthoquinone in the presence of a catalytic amount of L-proline in...

The 1-{[(1H-1,2,3-Triazol-4-yl)methoxy]phenyl}-1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives 5 were synthesized by a simple and efficient method, i.e., by the four-component, one-pot condensation reaction of phthalohydrazide 4, a (propargyloxy)benzaldehyde 1, an active methylene compound 3 (malononitrile or ethyl cyanoacetate), and an azide...

Sulfonic acid group–functionalized nano- and microsilica with different sizes and shapes were synthesized. Silica nanospheres with an average size of 225 nm, silica microtubes, and fine silica gel were prepared and functionalized by sulfonic acid. Their catalytic activity was investigated in the three-component Biginelli reaction for the synthesis...

The combination of the Biginelli reaction with click chemistry has been used for the one-pot synthesis of 1,2,3-triazole linked dihydropyrimidinones from azides, aromatic aldehydes containing a propargyl ether group, urea, and 1,3-dicarbonyl compounds using Cu(OAc)(2)/sodium ascorbate as catalyst in acetic acid under mild reaction conditions.

New and efficient multi-component methods have been developed for the synthesis of spirooxindoles in the presence of a catalytic amount of p-TSA as an inexpensive and available catalyst in EtOH under ultrasound irradiation. The method is simple, starts from readily accessible commercial starting materials, and provides biologically interesting prod...

a b s t r a c t An efficient one-pot synthesis of fluorescent hydroxyl naphthalene-1,4-dione derivatives by a simple, atom-economical and three-component reaction of 2-hydroxynaphthalene-1,4-dione, aromatic alde-hydes and heterocyclic or carbocyclic amines in the presence of a catalytic amount of InCl 3 in refluxing water is reported. The structure...

A three-component condensation reaction between 2-aminobenzophenone derivatives, formaldehyde or aromatic aldehydes, and ammonium acetate efficiently provides substituted quinazolines in a one-pot reaction in the presence of Brönsted acidic ionic liquid, 1-methylimidazolium triflouroacetate ([Hmim]TFA), in conjunction with aerobic oxidation. The io...

A facile and highly efficient method for one-pot four-component synthesis of triazolyl methoxy phenylquinazolines is described. A mixture of aromatic propargylated aldehydes, different azides, 2-aminobenzophenone derivatives, and ammonium acetate were condensed in the presence of catalytic amounts of acidic ionic liquid, 1-methylimidazolium trifluo...

A novel, simple, and green one-pot cyclocondensation reaction is presented by using an inexpensive and easily available catalyst.

AbstractAn effective one-pot three-component route to 4(3H)-quinazolinones from commercially available starting materials is reported. Thus, isatoic anhydride reacted with ammonium acetate or primary amines and aldehydes in the presence of iodine to produce the corresponding quinazolinone derivatives in moderate to good yields. Graphical Abstract...

4-Substituted-spiro-1,2-dihydroquinazolines and related compounds were synthesized by direct reaction of 2-aminobenzophenones, isatin, or 1,2-diketone derivatives and ammonium acetate in the presence of dual role catalyst-solvent ionic liquid, [Hmim]TFA. Excellent conversion of starting materials was achieved to the desired 1,2-dihydroquinazoline p...

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

The enantioselective alkylation of aryl aldehydes by diethylzinc in the presence of catalytic amounts of several novel chiral imino alcohol ligands, synthesized from the reaction of (R)-2-amino-1-butanol with aromatic aldehydes, was studied. The influence of temperature and ligand structure was investigated and enantioselectivity up to 81% was obta...