Ming Cai

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Verified

Ming verified their affiliation via an institutional email.

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• PhD
• Professor at Zhejiang University of Technology

Scope: Gallic acid (GA) is recognized for its purported antiinflammatory properties. GA has been demonstrated to prevent and alleviate the symptoms of chronic colitis through the modulation of the gut microbiota, improvement of the intestinal barrier, and reduction of inflammation. Methods and results: In order to determine the mechanism by whic...

Visible and Near-infrared hyperspectral imaging (VNIR-HSI) combined with machine learning has shown its effectiveness in various detection applications. Specifically, the quality of cigar tobacco leaves undergoes subtle changes due to environmental differences during the air-curing phase. This study aims to evaluate the feasibility of deep learning...

Polysaccharides from Dendrobium officinale have garnered attention for their diverse and well-documented biological activities. In this study, we isolated three ethanol-fractionated polysaccharides from Dendrobium officinale (EPDO) and investigated their digestive properties and effects on gut microbiota regulation in vitro. The results indicated t...

Gastritis is a common disease characterized by gastric ulcer and more severe bleeding. Daily intake of large amounts of alcohol can cause acute gastritis, which brings inconvenience to people's lives....

The tiger nut (Cyperus esculentus L.) is an ideal raw material for oil extraction, but the starch-rich tiger nut meal, a by-product of oil extraction, has not been fully utilized. For this, starch was isolated from the tiger nut meal, then starch nanoparticles were prepared by gelatinization, ultrasonication and nanoprecipitation under different co...

Background Over the past three decades, solid-state fermentation (SSF) has gained much attention in biotechnology, allowing efficient production of feed, fuels, industrial enzymes, etc., accompanied by less wastewater and less risk of contamination than submerged fermentation (SmF). Meanwhile, mycoproteins obtained using plant biomass to culture fu...

Soybean meal is a class of by-products obtained from the processing of soybean products. Despite its high nutritional value, the presence of glycoside isoflavones limits human use of soybean meal. This study evaluated the effect of solid-state fermentation (SSF) with different edible mushroom mycelia (Pleurotus ostreatus, Hericium erinaceus, and Fl...

Hericium erinaceus is a kind of large fungus with rich nutrition and its polysaccharides exhibit various biological activities. In recent years, widespread interest has been focused on maintaining or improving intestinal health through the consumption of edible fungi. Studies have shown that hypoimmunity can damage the intestinal barrier, which in...

This study was to investigate the antifatigue, prebiotic effects and their relationships to the structure properties of three ethanol precipitated polysaccharides from Dendrobium officinale (EPDO), as EPDO-40, EPDO-60 and EPDO-80. EPDOs with anti-fatigue activity were screened out by forced swimming test, and blood lactic acid (BLA), blood urea nit...

BACKGROUND The gut microbiota (GM) is recognized as a significant contributor to the immune system. In the present study, the effects of Hericium erinaceus polysaccharides (HEP) on immunoregulation and GM in cyclophosphamide (CTX)‐treated mice were investigated to elucidate the attenuate of immunosuppression by modulating GM. RESULTS The results r...

Agaricus blazei murrill (ABM), a large fungus, is reported to have extensive biological activities but the antioxidant and immune-regulatory capacities have been less studied and the components responsible for the functions are unclear. This study prepared ABM peptides (ABMP) using ultrasound-assisted enzymatic extraction (UAEE) strategy and cascad...

Hydroxyl radical has been widely applied in the non-food fields, but whether its feasibility for treating fruits and vegetables remains unknown. In this work, effects of hydroxyl radical water (HRW) treatment on functional components, volatile compounds, and preservation properties of cherry tomato, grape, coriander and celery were investigated. Re...

Ethanol fractional precipitation is an important technology to classify polysaccharides at different molecular weights. In this study, polysaccharides of Dendrobium officinale were step-precipitated by final ethanol concentrations of 40%, 60% and 80%, named as EPDO-40, EPDO-60 and EPDO-80, respectively. Chemical composition, molecule weights and mo...

Bioaccessibility and bioactivity of flavonoids in lotus leaves are related to their characteristics in gastrointestinal digestion and colonic fermentation. The aim of this study is to investigate the stability of lotus leaf flavonoids (LLF) in simulated gastrointestinal digestion, and its modulation on gut microbiota in vitro fermentation. Results...

Non-thermal sterilization technology is considered a safe and effective approach in controlling postharvest losses of fruit. In this study, the effects of pulsed light (PL) on qualities of Chinese bayberries during storage at 10 °C, 95% RH for 12 d were investigated. At the same time, high-throughput sequencing was operated to identify fungal micro...

Starch nanoparticles (SNPs) were produced from sweet potato starches by ultrasonic treatment combined with rapid nanoprecipitation. The starch concentration, ultrasonic time, and the ratio of starch solution to ethanol were optimized through dynamic light scattering (DLS) technique to obtain SNPs with a Z-average size of 64.51 ± 0.15 nm, poly dispe...

The purpose of this study was to compare the effects of sweet potato peels dietary fiber obtained by different extraction methods on intestinal health. Specifically, four different dietary fibers were extracted by hot water, microwave, ultrasonic and subcritical water methods. And the prebiotics effects of sweet potato peels dietary fibers were exp...

This study is to evaluate the athermal forward osmosis (FO) concentration process of blueberry juice using food additives as a draw solution (DS). The effects of food additives, including citric acid, sodium benzoate, and potassium sorbate, on the concentration processes are studied, and their effects on the products and membranes are compared. Res...

In this study, cascade membrane technology was applied to classify polysaccharides from the peels of stem lettuce (PPSLs), and three graded polysaccharides (PPSL100, PPSL10, and PPSL1) were obtained using ultrafiltration membranes of 100, 10, and 1 kDa in sequence. The physicochemical properties and immune-modulatory activity of three PPSLs fractio...

This study explored the structure characteristics of an oligosaccharide from Ganoderma lucidum (GLO) and its regulatory functions on intestinal flora fermentation in vitro. GLO was extracted by ultrasonic-assisted enzymatic hydrolysis, and purified with a dextran gel column. Digestion properties and intestinal flora regulation effects of GLO were i...

Mycotoxins produced by Aspergillus spp., Penicillium spp. and Fusarium spp. with small molecular weight and thermal stability, are highly toxic and carcinogenic secondary metabolites. Mycotoxins have caused widespread concern regarding food safety internationally because of their adverse effects on the health of humans and animals, and the major ec...

Purpose A high-fat diet (HFD) induces gut microbiota (GM) disorders, leading to intestinal barrier dysfunction and inflammation. Ferulic acid (FA) has shown anti-obesity effects, e.g., reducing body weight and food intake. However, the mechanism linking the anti-obesity effects of FA and GM modulation remains obscure. The present study aimed to cla...

Ganoderma lucidum is known as a medicine food homology that can ameliorate gastrointestinal diseases. To evaluate the gastroprotective effects on different Ganoderma lucidum polysaccharides (GLPs), GLP was separated into three parts with different molecular weights using 100 kDa, 10 kDa, and 1 kDa membranes. The mitigation effects of different GLPs...

With the rapid development of the edible fungi industry in the world, especially in China, the resource utilization of edible fungi by-products has become an urgent problem for the industry's sustainable development. The waste residue of edible fungi after polysaccharide extraction by water accounts for a large proportion, which contains a large am...

Polysaccharides of Dendrobium officinale (DOP) need to be dehydrated and concentrated after extraction for further application. They are usually concentrated by thermal evaporation which consumes great energy. However, high viscosity of DOP makes the concentration more difficult even using non‐thermal membrane technologies such as nanofiltration (N...

Effective packages can extend shelf life and quality of mushrooms in storage. This study is to investigate the effects of nano-SiO2/nano-TiO2 loaded polyvinyl alcohol (PVA) packages on preservation of Agaricus bisporus. Quality properties, including weight loss, respiration rate, color, total soluble solid, pH, malondialdehyde content, electrolyte...

In this paper, cascade membrane technology was utilized to classify polysaccharides from Ganoderma lucidum (GLPs). The properties and antifatigue activity of graded polysaccharides were identified and compared. GLPs were separated using cascade ultrafiltration membranes of 100 kDa, 10 kDa and 1 kDa in sequence. The molecular weights of polysacchari...

Anthocyanins-rich blueberry extracts, which commonly used as food additive, are good for human health, but they are unstable during concentration processes. In this study, five flat-sheet nanofiltration (NF) membranes were used to concentrate the blueberry aqueous extracts. Effects of different membranes on physicochemical characteristics of concen...

Edible mushrooms have potential in anti-diabetic phytotherapy. They are rich in natural compounds such as polysaccharides, which have been known to have antihyperlipidemic effects since ancient times. A polysaccharide fraction of PP80 and a contained low molecular-weight (Mw), water-soluble polysaccharide (PPW-1, Mw: 3.2 kDa) were isolated from the...

Dietary intervention in type 2 diabetes mellitus (T2DM) is a hotspot in international research because of potential threats to human health. Phellinus baumii, a wild fungus traditionally used as a food and medicine source, is now cultivated in certain East Asian countries, and is rich in polyphenols, which are effective anti-inflammatory ingredient...

Organic fouling in the nanofiltration (NF) process, which is a non-thermal technology to recover active components, is a critical problem limiting its applications. This study seeks to identify the anthocyanins on the NF membrane and explore their fouling mechanisms during concentration of blueberry extracts. Seven kinds of monomeric anthocyanins i...

Finger citron essential oil (FCEO) is a potential resource in pharmaceutical and food industries. FCEO encapsulated by nanoemulsion can overcome its insoluble and unstable disadvantages, and prolong its digestion in the colon. This study investigated the effects of FCEO on human gut microbiota by in vitro fermentation. The results showed supplement...

Ganoderma lucidum spores (GLS) constitute a healthy food for humans, but the hard spore shells are difficult to digest. In this study, digestive properties of GLS in different forms (sporoderm-unbroken, sporoderm-broken [SB-GLS] and sporoderm-removed [SR-GLS]) were investigated in vitro digestion and fermentation. After simulated digestion, morphol...

Sesame is an oil crop with high nutritional value. Protein is one of the main ingredients of sesame, however research on protein of cold-pressed sesame cake is limited. This study aimed to investigate the effects of ultrasonic pre-treatment (UPT) on physicochemical properties of proteins (yield, solubility, amino acid composition, surface propertie...

Larou is a traditional smoked meat product in China. In this experiment, larou was processed with different smoking materials and methods to determine whether differences in processing methods would affect the quality of the larou and the concentrations of carcinogens. Pork bellies were marinated, dried, and divided into four groups and then direct...

Flax (Linum usitatissimum) is a member of family linaceae with annual growth habit. It is included among those crops which were domesticated very early and has been used in development related studies as a model plant. In plants, Calmodulin-binding transcription activators (CAMTAs) comprise a unique set of Calmodulin-binding proteins. To elucidate...

Effects of various factors, such as membrane materials, molecular weight cutoff, transmembrane pressure (TMP), and cross flow rate (CFR) on flux and physicochemical properties of apple juice during ultrafiltration and storage have been investigated. Clarity, color, total phenols, total proteins, total sugars, total soluble solids (TSS), pH, and som...

Until recently, a variety of oligosaccharides from fruits, vegetables and mushrooms have demonstrated positive prebiotic effects. Ganoderma lucidum, a well-known traditional medicine and tonic in East Asia, has been utilized in the prevention and treatment of a broad range of illnesses. In this study, each of three oligosaccharides was obtained fro...

The Detoxification Efflux carriers (DTX)/Multidrug and Toxic Compound Extrusion (MATE) transporters encompass an ancient gene family of secondary transporters involved in the process of plant detoxification. A genome‐wide analysis of these transporters was carried out in order to better understand the transport of secondary metabolites in flaxseed...

Previous studies have been reported that the fruit body of wild Phellinus baumii alleviates diabetes, and antioxidants are beneficial to diabetes by protecting the β-cell from damage due to oxidative stress. Large-scale cultivation of P. baumii fruit body has been successful in the past decade. This paper aimed to investigate whether the fruit body...

The use of anthocyanins are limited by their chemical properties. Recent evidence suggests Cyanidin-3-O-glucoside (C3 G) liposomes via the ethanol injection method exhibit improved stability. In the current study, the characterization and cell absorption of C3 G liposomes were explored via transmission electron microscopy and flow cytometry. The in...

Although sulfites are widely used in shrimp processing, the contents of residual sulfite need to be strictly controlled due to their potential toxicity. In this paper, a novel method was developed for determination of the free and total sulfites in shrimps. Major procedures of the method includes separation of free and total sulfites with ultrasoun...

In this work, antibacterial activity of finger citron essential oil (FCEO, Citrus medica L. var. sarcodactylis) and its mechanism against food-borne bacteria were evaluated. A total of 28 components in the oil were identified by gas chromatography-mass spectrometry, in which limonene (45.36%), γ-terpinene (21.23%), and dodecanoic acid (7.52%) were...

Cadmium, with its high toxicity rate to plants and potential threat to human health, is a dangerous pollutant in the environment. Uptake and accumulation by crops represent the main entry pathway for potentially health-threatening toxic metals into human and animal food. Crops and other plants take up Cd from the soil or water and may distribute it...

Fruit juice is a complex mixture, in which polyphenols are active compounds for human health. In this paper, the effects of membrane properties, such as materials and molecular weight cutoff (MWCO), on fouling behavior of four typical polyphenols in model fruit juice ultrafiltration process were investigated. Zeta potential, contact angle, SEM imag...

Understanding membrane fouling mechanisms of key nutrition indicators in fruit juices during nanofiltration (NF) are important for quality control of products and manufacture processes. This study evaluated the effects of operating and molecular parameters of six phenolic compounds on fouling resistances during NF with two membranes. Results showed...

Behavior and rejection mechanisms of typical phenolic compounds in fruit juice during nanofiltration (NF) are not clear. Because the system of actual fruit juice is very complex, in this study, rejection mechanisms of six typical fruit juice phenolic compounds in model solutions with two NF membranes were investigated. Molecular structure parameter...

In this study, crude polysaccharides of culinary-medicinal mushroom Auricularia auricular-judae were extracted by hot water extraction and alcohol precipitation, and their antimicrobial and antioxidant activities were investigated. An optimum extraction condition was obtained at a ratio of liquid to solid 70 mL/g, temperature 90°C, time 4 h and ext...

In this study, the effects of ultrasonic parameters on permeate flux and fouling resistances in the ultrasound-assisted ultrafiltration (UAUF) process of Radix astragalus extracts with hollow fiber membrane (HFM) was investigated. Ultrasonic parameters such as frequency, power and irradiation mode all can significantly affect the flux and fouling d...

Shikimic acid is a main raw intermediate for manufacturing oseltamivir phosphate (Tamiflu), which is the only antiviral treatment for Influenzavirus A (H5N1 and H2N1), recently. Chinese star anise is a natural resource of shikimic acid which can be extracted by some typical technologies. Two effective technologies, ultrasound-assisted extraction (U...

In this study, microwave-assisted extraction with ethanol (MAEE) of star anise oil from Illicium verum Hook.f. has been optimised by response surface methodology (RSM). A maximum yield of star anise oil was obtained at an optimum condition: the ratio of solvent to sample 17 mL g−1, extraction time 16 min and microwave power 505 W. Accordingly, the...

A semi-empirical model has been developed in ultrafiltration of huanggi (Radix astragulus) extracts. Three major fouling resistances were quantified with transmembrane pressure (TMP) ranged from 0.4 to 0.8 bar and process time lasted for 120 min. Adsorption grew fast at the initial 15 min and its contribution was more significant at 0.4 bar, nearly...

Response surface methodology (RSM) with a central composite rotatable design (CCRD) was employed to optimize the process of ultrasound-assisted ultrafiltration (UF) for Radix astragalus mixtures. The effects and mutual interaction of several parameters, namely ultrasonic power, ultrasonic irradiation mode, trans-membrane pressure (TMP) and temperat...

In this paper, we demonstrate a colorimetric visual detection of melamine in milk simply using citrate-stabilized Au nanoparticles (NPs). Due to strong interaction between melamine and Au NPs, all of the Au NPs sensors present a significant and sensitive color change in the presence of ppb-level melamine, which can be directly observed by the naked...

The mechanisms for ultrasounds (USs) at the frequencies of 28, 45 and 100kHz on ultrafltration (UF) and membrane cleaning were investigated in dead-end UF cell with dextran aqueous solution. Permeate flux and resistances at different US frequencies were recorded and calculated in terms of resistance-in-series model, respectively. The flux enhanceme...

The objective of this study was to evaluate the effect of ultrasound (US) on the ultrafiltration (UF) of a natural product, Radix astragalus (RA) aqueous extract, and the cleaning process of fouled membrane. Specifically, the effects of ultrasonic frequency, power and irradiation mode on flux and resistances in UF processes were investigated. Ultra...

Microwave-assisted extraction (MAE) was applied to the extraction of saikosaponin a, c and d from Radix Bupleuri. Several operating parameters, namely microwave power, time, temperature and ethanol concentration, were optimized using response surface methodology (RSM) with a central composite rotatable design (CCRD). The ethanol concentration and t...

Multi-stage countercurrent extraction technology, integrating solvent extraction, repercolation with dynamic and countercurrent extraction, is a novel extraction technology for the traditional Chinese medicine. This solvent-saving, energy-saving and high-extraction-efficiency technology can at the most drive active compounds to diffuse from the her...

To investigate the process factors and characteristic of four-effect countercurrent extracting process of Danshensu from Salvia miltiorrhiza. Optimizing the parameters by using regression analysis and principal components analysis (PCA). Applying the orthogonal design method to optimize the extracting process. The factors of extraction time, solven...