About
347
Publications
42,536
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
8,547
Citations
Publications
Publications (347)
Fine particulate matter (PM2.5) is known to exacerbate chronic respiratory disorders, primarily by inducing inflammatory responses and mucus overproduction. Perilla leaves are reported to have significant health benefits, such as antioxidant, antibacterial, and antiallergic properties, attributed to phenolic compounds that vary depending on genetic...
In this paper, a method using a semantic segmentation method based on edge-region focal loss was proposed to estimate the heading angle of resin in a catheter-extrusion process. The approach leveraged an improved semantic segmentation facilitated by this new loss function and principal component analysis. Accurate heading angle estimation was criti...
Trampolines are recognized as a valuable tool in exercise and rehabilitation due to their unique properties like elasticity, rebound force, low-impact exercise, and enhancement of posture, balance, and cardiopulmonary function. To quantitatively assess the effects of trampoline exercises, it is essential to estimate factors such as stiffness, eleme...
Despite advances in precision oncology, cancer remains a global public health issue. In this report, proof‐of‐principle evidence is presented that a cell‐penetrable peptide (ACP52C) dissociates transcription factor CP2c complexes and induces apoptosis in most CP2c oncogene‐addicted cancer cells through transcription activity‐independent mechanisms....
Osteoporosis is a malady of multiple cell types associated with the bone marrow (BM) fat accumulation. This study focused on understanding the role of adiponectin in osteoblast and osteoclast lipid metabolism in diabetic and ovariectomized mice with osteoporosis and exploring the effects of the adiponectin receptor (AdipoR) agonist, AdipoRon. Adopo...
Proteins play a crucial role in many biological processes, where their interaction with other proteins are integral. Abnormal protein-protein interactions (PPIs) have been linked to various diseases including cancer, and thus targeting PPIs holds promise for drug development. However, experimental confirmation of the peculiarities of PPIs is challe...
Four-dimensional (4D) light-field (LF) microscopes can acquire 3D information about target objects using a microlens array (MLA). However, the resolution and quality of sub-images in the LF images are reduced because of the spatial multiplexing of rays by the element lenses of the MLA. To overcome these limitations, this study proposes an LF one-sh...
e18004
Background: Erb-b2 receptor tyrosine kinase 3 (HER3) is broadly expressed in various types of cancer and is associated with poor prognosis. Recent evidence supports HER3 plays a role in acquired resistance to chemotherapy. The change of HER3 expression by chemotherapy in head and neck squamous cell carcinoma (HNSCC) remains unclear. Methods:...
Image-to-patient registration is a coordinate system matching process between real patients and medical images to actively utilize medical images such as computed tomography (CT) during surgery. This paper mainly deals with a markerless method utilizing scan data of patients and 3D data from CT images. The 3D surface data of the patient are registe...
We propose a light-field microscopy display system that provides improved image quality and realistic three-dimensional (3D) measurement information. Our approach acquires both high-resolution two-dimensional (2D) and light-field images of the specimen sequentially. We put forward a matting Laplacian-based depth estimation algorithm to obtain nearl...
Alzheimer's disease (AD), one of the most representative neurodegenerative diseases, has diverse neurobiological and pathophysiological mechanisms. Treatment strategies targeting a single mechanism have repeated faced failures because the mechanism of neuronal cell death is very complex that is not fully understood yet. Since complex mechanisms exi...
Transcription factor CP2c (also known as TFCP2, α-CP2, LSF, and LBP-1c) is involved in diverse ubiquitous and tissue/stage-specific cellular processes and in human malignancies such as cancer. Despite its importance, many fundamental regulatory mechanisms of CP2c are still unclear. Here, we uncover an unprecedented mechanism of CP2c degradation via...
A robust perception system is critical in autonomous driving. It is responsible for object detection, classification, and ranging under challenging circumstances. Camera and lidar sensors provide complementary information, and by combining these two modalities, we can increase the robustness and accuracy of the overall perception system. This paper...
In the wake of COVID-19, the digital fitness market combining health equipment and ICT technologies is experiencing unexpected high growth. A smart trampoline fitness system is a new representative home exercise equipment for muscle strengthening and rehabilitation exercises. Recognizing the motions of the user and evaluating user activity is criti...
This study was conducted to evaluate the biological activities of sweet potato tips and tubers. Antioxidant activity of 2,2‐azino‐bis 93‐ethlbenzothiazoline‐6‐sulphonic acid) diammonium salt (ABTS) and 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) radical scavenging activities had the highest value of 32.45 mg, AAE/g, and 15.10 mg AAE/g, respectively, in ‘P...
CP2c, also known as TFCP2, α-CP2, LSF, and LBP-1c, is a prototypic member of the transcription factor (TF) CP2 subfamily involved in diverse ubiquitous and tissue/stage-specific cellular processes and in human malignancies including cancer. Despite its importance, many fundamental regulatory mechanisms of CP2c are still unclear. Here, we uncover un...
The use of thermal sensors is increasing in response to dealing with the problems of the visible light spectrum. These sensors measure the temperature of the object and convert it to some readable output. There is a diverse range of temperature sensors, and different sensors are used for different purposes. The choice of the sensor depends on the c...
Vision, Radar, and LiDAR sensors are widely used for autonomous vehicle perception technology. Especially object detection and classification are primarily dependent on vision sensors. However, under poor lighting conditions, dazzling sunlight, or bad weather an object might be difficult to be identified with general vision sensors. In this paper,...
Due to the recent spread and long-term continuation of COVID-19, numerous non-contact body temperature measuring equipment is being introduced in public places to prevent cross-infection. Therefore, extensive research on the non-contact body temperature measurement method, using a thermal imaging camera, is being conducted globally. The existing me...
We propose and implement a high-quality three-dimensional (3D) display system for an integral imaging microscope using a simplified direction-inversed computation method based on user interaction. A model of the specimen is generated from the estimated depth information (via the convolutional neural network-based algorithm), the quality of the mode...
This paper proposes an automatic cast product surface defect detection system based on deep learning artificial intelligence technology. Application of deep learning is difficult because of the uneven surface and small defects of the cast product which are easily affected by the lighting position and angle. Therefore, three channel fusion data from...
Stereo photogrammetry is a fundamental technique for 3D measurements in different applications. As passive stereo methods struggle in texture-less regions, different light-coded patterns are projected to solve the correspondence problem. When the reconstruction method requires a series of sequentially coded light patterns, the system is prone to mo...
Compared to the side view, a top-view is robust against occlusion generated by objects located indoors. It offers a better wide view angle and much visibility of a scene. However, there are still problems to be handled. The top-view image shows asymmetrical features and radially distorted scenes around the corners, such as omnidirectional view imag...
This study investigated the physicochemical properties of rice flour suspensions under ultrahigh hydrostatic pressure (UHP) treatment. Rice flour suspensions were subjected to 200, 400, and 600 MPa of pressure for 10 min, and heat treatment was used as a control. Proximate characteristics of different rice cultivar were analyzed to amylose, damage...
A three-dimensional mobile system with advanced visualization based on image super-resolution method is proposed and implemented. Here, real object information is acquired using three-dimensional scanning, and the three-dimensional visualizations of the object with the improved resolution are displayed on the mobile display with user interaction fu...
The speckle pattern is highly prevalent in stereo-photogrammetry systems. The speckles generated by the laser and the diffuser are influenced by the subjective noise and change the appearance with the distance. In addition to this, the density of the 3D point cloud is a major stumbling block when only one pattern for reconstruction is allowed. In t...
We aimed to develop an efficient process for producing red yeast rice (RYR) with different rice cultivars (Samkwang: used for cooking and Hangaru: used for processing) and amounts of added water (0–100%). Our analyses showed that Hangaru rice had a round starchy form with 18.62% amylose content, and Samkwang rice exhibited an angular starchy form w...
This study was performed to investigate the distribution of phenolic compounds in the peanut skins of various cultivars, as well as their antioxidant and anti‐inflammatory effect (Arachishypogaea L. cv. K‐Ol, cv. Sinpalkwang, cv. Daan, cv. Heuksaeng) and extraction solvent. The major components of red peanut cultivars (K‐Ol, Sinpalkwang, and Daan)...
The objective of this study was to evaluate the effects of heat treatment on the phenolics and antioxidant activity of rice hull. Heat treatment was performed at temperatures 80∼140°C for 1∼5 h, and the heated rice hull was extracted with 80% (v/v) methanol in an ultrasonic bath. The highest total polyphenol and flavonoid content (10.68 mg gallic a...
Advanced image sensors with high resolution are now being developed for specially purposed electro-optical systems, with research focused on robust image quality performance in terms of super resolution and noise removal under various environmental conditions. Recently, machine-learning and deep-learning methods have been studied as the best practi...
In this paper, we propose an advanced three-dimensional visualization method for an integral imaging microscope system to simultaneously improve the resolution and quality of the reconstructed image. The main advance of the proposed method is that it generates a high-quality three-dimensional model without limitation of resolution by combining the...
Tactile sensors have been widely used and researched in various fields of medical and industrial applications. Gradually, they will be used as new input devices and contact sensors for interactive robots. If a tactile sensor is to be applied to various forms of human–machine interactions, it needs to be soft to ensure comfort and safety, and it sho...
The objective of this study was to investigate the structural and physicochemical properties of starch from seven sweet potato cultivars (Shinyulmi, Sinjami, Hogammi, Jeonmi, Jinyulmi, Juhwangmi, and Pungwonmi). Jeonmi and Jinyulmi had amylose contents of 40.04% and 37.39%, respectively, whereas Juhwangmi and Pungwonmihad amylose contents of 30.95%...
Typical visual placement inspection systems in semiconductor or electronics manufacturing industries use only highly-magnified two-dimensional imaging with controlled illumination for high accuracy. However, current semiconductor packaging technology needs more precise manufacturing processes for highly integrated semiconductor packages, in which h...
Chromatin remodeling, including histone modification, chromatin (un)folding, and nucleosome remodeling, is a significant transcriptional regulation mechanism. By these epigenetic modifications, transcription factors and their regulators are recruited to the promoters of target genes, and thus gene expression is controlled through either transcripti...
Automatic segmentation of intracellular compartments is a powerful technique, which provides quantitative data about presence, spatial distribution, structure and consequently the function of cells. With the recent development of high throughput volumetric data acquisition techniques in electron microscopy (EM), manual segmentation is becoming a ma...
Although recently developed trackers have shown excellent performance even when tracking fast moving and shape changing objects with variable scale and orientation, the trackers for the electro-optical targeting systems (EOTS) still suffer from abrupt scene changes due to frequent and fast camera motions by pan-tilt motor control or dynamic distort...
Unmanned aerial vehicles and battleships are equipped with the infrared search and tracking (IRST) systems for its mission to search and detect targets even in low visibility environments. However, infrared sensors are easily affected by diverse types of conditions, therefore most of IRST systems need to apply advanced contrast enhancement (CE) met...
The high-quality visualization method for integral imaging microscope using deep learning depth estimation algorithm is proposed. The point cloud model is regenerated from the accurate depth information and a high-resolution image and displayed.
This study was performed to investigate the cooking characteristics and sensory evaluation of rice cooked in the presence of 20 % germinated barley. The soluble solid and water absorption rate increased significantly with longer barley germination periods. The microstructure of the cooked germinated barley showed some pores 4 days after germination...
Background:
To overcome disadvantages of germinated brown rice, we germinated rough rice and tested effects of its useful ingredients on prevention of diabetes.
Objective:
This study investigated the in vitro antioxidant and in vivo antidiabetic effects of rough rice (Oryza sativa L.) with hulls, before and after germination. Rough rice was germ...
Although intrinsically disordered protein regions (IDPRs) are commonly engaged in promiscuous protein-protein interactions (PPIs), using them as drug targets is challenging due to their extreme structural flexibility. We report a rational discovery of inhibitors targeting an IDPR of MBD2 that undergoes disorder-to-order transition upon PPI and is c...
BACKGROUND
The ability of heat treatment with a soaking solvent to increase soluble phenolic compounds due to the liberation or breakdown of the cell matrix has been investigated in various plants. This study investigated the changes in phenolic compounds and antioxidant activities of 12 sweet potato cultivars after heat treatment with distilled wa...
NOx, a generic term for the nitrogen oxides generated from combustion in the presence of nitrogen, is a serious threat to human health. This study examined the removal of NOx using ammonia (NH3) and ozone produced using a silent discharge method. The effects of temperature and residence time on NOx removal with NH3 injection in a double reactor sys...
Metformin is a widely used drug for the treatment of type 2 diabetes. Antidiabetic drugs are also known to influence cancer progression, as high glucose levels affect both cancer and diabetes. Metformin induces cell cycle arrest in cancer cells, but the underlying mechanism remains unclear in cervical cancer system. Here, we examined how metformin...
We aimed to investigate the effect of high pressure treatment (HPT) on the physical properties of surimi sausages. For protein gelation, high hydrostatic pressure of 400, 500, and 600 MPa was applied for 5, 15, and 30 min, respectively. Elasticity of samples containing 50% surimi was 36.68%, but that of samples containing 70% surimi was 36.87–42.88...