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Publications (232)
Autologous platelet concentrates are rich in growth factors and have shown potential for high anatomical success rates in macular hole treatment. However, no systematic review has yet assessed its impact. Therefore, this study aimed to conduct a comprehensive review and meta-analysis on the comparative efficacy and safety of autologous platelet con...
HIV-induced AIDS attacks the immune system, leading to opportunistic infections. This syndrome has been linked to an increased risk of developing uveitis and subsequent cataracts. Consequently, cataract surgery may be associated with intra- and postoperative complications in HIV/AIDS patients. We conducted a systematic review and meta-analysis to i...
Background:
This study compared the refraction measurements of the QuickSee wavefront autorefractor with those from clinical refraction measurements in preschool and elementary school children from public schools in Amazonas, Brazil.
Methodology:
Refractometry was performed on 368 eyes from 368 healthy Brazilian public school students aged 4 to 7...
Purpose
To evaluate the visual, topographic, and refractive outcomes of the implantation of asymmetric segments (AS) of the ICRS intracorneal ring in eyes with keratoconus and irregular/asymmetric astigmatism (phenotypes type 2 Duck and 3 Snowman by morphological classification of Fernandez-Vega/Alfonso Keratoconus).
Methods
Prospective clinical s...
Introduction
Macular holes are breaks in the retinal tissue at the center of the macula, affecting central vision. The standard treatment involves vitrectomy with membrane peeling and gas tamponade. However, for larger or chronic holes, alternative techniques like autologous retinal graft have emerged. This meta-analysis evaluates the efficacy and...
This systematic review and meta-analysis evaluated the efficacy and safety of autologous human serum as an adjuvant agent in pars plana vitrectomy (PPV) for macular holes (MH). Thus, a comprehensive search was conducted across PubMed, Web of Science, Embase, and the Cochrane Library databases up to August 20th, 2023. The inclusion criteria targeted...
Purpose: This study aimed to demonstrate the importance of long-term follow-up after corneal collagen crosslinking.
Methods: This case report showed an intense progressive flattening of keratometric parameters in a patient without risk factors such as high maximum keratometry, thin cornea, uncontrolled ocular allergy, collagen, or rheumatologic dis...
Keratoconus is a progressive condition in which the cornea has a conical shape secondary to a noninflammatory stromal thinning. As a consequence, astigmatism, myopia, and variable visual impairment are observed. Intrastromal corneal ring segments (ICRSs) have been used as a safe and effective surgical treatment for keratoconus to regularize corneal...
Purpose
Evaluate blue-violet light filter and additional power of +0.40 D in the near zone ophthalmic lenses, on convergence, accommodative functions, and symptoms of digital asthenopia (DA).
Methods
Randomized study in cross-over design conducted on 49 volunteers (age, 29 ± 5.5 years; male: female, 18:31). Each subject wore test (+0.40 D in the n...
ABSTRACT Objective: To evaluate the efficacy of low-cost nucleus fragmenting forceps designed to reduce the use of ultrasound during phacoemulsification. Methods: A total of 60 pig eyes enucleated 10 hours before were placed in the microwave oven, at maximum power for 10 seconds, to form cataracts with hardness comparable to a grade IV nucleus in t...
Objective:
To evaluate the standards of practice of Brazilian cataract surgeons in relation to the protective measures adopted to mitigate the risks of transmission of COVID-19 during cataract surgery, in asymptomatic patients.
Methods:
A descriptive, cross-sectional, quantitative paradigm study, developed from a self-administered electronic que...
Background:
Elderly patients may present with visual function impairment after surgery, which may increase the incidence of postoperative delirium and falls and decrease their quality of life. The aim of this study was to assess visual function in elderly patients after long-duration nonocular surgery to determine the incidence and risk factors fo...
ABSTRACT We report a case of two twins for whom advanced keratoconus is present in one of the siblings and no clear sign of the disease could be found for the other.
Objective:
We aimed to describe the clinical and phenotypic manifestations as well as the visual prognosis of a family with CA in Northeastern Brazil.
Methods:
This was a cross-sectional study involving 31 individuals (56 eyes) from the same family presenting CA phenotypes. The study population resided in the municipality of Água Branca, in the...
Objective:
Evaluate the sensitivity, specificity e accuracy of the ocular refraction measured by the 2WIN® photoscreener as a screening method to identify children in need of spectacles prescription according to the criteria published by the Brazilian Society of Pediatric Ophthalmology (BSPO) in asymptomatic children, 6 to 36 months old, and determ...
Purpose:
To determine whether codeine plus acetaminophen after photorefractive keratectomy (PRK) have beneficial effects on sleep quality, activity levels, and food intake, beyond their effect of pain relief.
Methods:
We enrolled 40 patients (80 eyes) in this randomized, double-blind, paired-eye, placebo-controlled, add-on trial. Each eye was tr...
Inflammation and oxidative stress accompany aging. This study aimed to investigate the interplay between oxidative stress and inflammation in the lacrimal gland (LG). C57BL/6 (B6) mice were used at 2-3, 12, and 24 months of age (2-3M, 12M, and 24M, respectively). Nuclear factor erythroid derived-2-related factor 2 (Nrf2)-/- and their corresponding...
Objective:
Compared to standard spectacle lenses, do +0.40 EyeZenTM lenses reduce symptoms of asthenopia induced by computer?
Methods:
A prospective clinical study was carried out with 39 volunteers who spent more than 4 hours a day using a computer (age, 27.31±4.24; male: female =13:26). Asthenopia and visual comfort were assessed using a questio...
Background:
The visual screening performed in schools is sometimes the only opportunity to detect uncorrected refraction errors (URE) causing low visual impairments, prejudice in the acquisition of knowledge, dropout and school repetition, poor motor skills, difficulty in social interaction and low self-esteem in schoolchildren.
Objectives:
To com...
Abstract Dry eye disease (DED) is common in Rheumatoid Arthritis (RA) patients. The application of conjunctival goblet cell count as a clinical biomarker to diagnose and respond to treatment can take place in rheumatoid arthritis patients under TNF-inhibitors (TNFi) therapy. This study aimed to investigate the ocular surface parameters and the long...
Purpose
This study compared riboflavin penetration in porcine corneas using two different solutions: dextran and hydroxypropyl methylcellulose (HPMC).
Methods
Porcine corneas were de-swollen and after prepared in an artificial anterior chamber with balanced saline solution. The pressure was checked with a portable tonometer. We used 0.1% riboflavi...
Purpose:
To compare the postoperative refractive predictability of IOLMaster 500 and Pentacam HR on the basis of keratometry and anterior chamber depth values in eyes with an indication for multifocal intraocular lens (IOL) implantation.
Methods:
This was a retrospective study conducted on 118 eyes treated with phacoemulsification and multifocal...
Dry eye disease can compromise the patient’s quality of life. Few studies assessed the ocular surface (OS) in Ankylosing Spondylitis (AS) patients. This study aimed to evaluate the clinical and cytological findings of the OS in patients with AS, classify dry eye disease (DED) severity grade and conjunctival impression cytology (IC), and the effects...
Purpose
To evaluate the influence of preoperative mitomycin C (MMC) on the proliferative behavior of fibroblasts and fibrovascular tissue derived from the primary pterygium using the immunohistochemical method (Ki67 and CD34).
Design
Randomized clinical trial.
Subjects, participants and/or controls
Sixty-five patients with primary pterygium were...
Objectives: To compare the aniseikonia and the stereopsis in school children anisometropes of the first-year of elementary school corrected with stock ophthalmic lenses with base curve selected to minimize the interocular size difference of retinal images and with size lenses suggested by the software Aniseikonia Inspector 3, and to check the prefe...
Abstract
Purpose
To assess outcomes and glaucoma management in eyes with aniridia following Boston type 1 Keratoprosthesis (KPro) implantation.
Design
Retrospective, interventional comparative case series.
Methods:Population
Patients with aniridia and patients with other preoperative diagnoses (excluding Stevens-Johnson syndrome, mucous membrane...
Aging is a complex process associated with dysregulation of the immune system and low levels of inflammation, often associated with the onset of many pathologies. The lacrimal gland (LG) plays a vital role in the maintenance of ocular physiology and changes related to aging directly affect eye diseases. The dysregulation of the immune system in agi...
Purpose
To assess the stability and reliability of femtosecond laser-assisted cataract surgery (FLACS) incisions design and dimensions using anterior segment optical coherence tomography (AS-OCT) imaging.
Setting
Renato Ambrósio Ophthalmologic Study Center from Hospital Oftalmológico de Brasília, Brasília, Brazil.
Design
Prospective nonrandomized...
Purpose:
To assess optic nerve head (ONH) and peripapillary microvasculature in primary open-angle glaucoma (POAG) of mild to moderate severity using swept-source optical coherence tomography angiography (OCTA).
Materials and methods:
In a cross-sectional study, swept-source OCTA images were analyzed for 1 eye from each of 30 POAG patients with...
OBJECTIVE
To evaluate the relationship of biomechanical properties, corneal hysteresis and corneal resistance factor with age, sex and various corneal parameters measured with a Pentacam in normal subjects.
METHODS
A total of 226 eyes from 113 patients were enrolled in this study. The subjects underwent Ocular Response Analyzer and Pentacam evalua...
Purpose:
To compare the antiinflammatory efficacy of topical nepafenac 0.3% for prophylaxis of macular edema after cataract extraction.
Setting:
São Paulo University, São Paulo, Brazil.
Design:
Prospective randomized clinical trial.
Methods:
Patients with bilateral cataract were included in this study. Each patient was assigned randomly to r...
Purpose
The purpose of this study was to compare intraoperative parameters between femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification using Centurion® Vision System with Active Fluidics.
Setting
This study was performed at Brasília Ophthalmologic Hospital, Brasília, Federal District, Brazil.
Patients and meth...
Purpose
To compare visual outcomes and performance between bilateral implantation of a diffractive trifocal intraocular lens (IOL) Acrysof®PanOptix® TFNT00 and blended implantation of two different near add power bifocal IOLs: Acrysof® Restor® SV25T0 in dominant eye and Acrysof® Restor® SN6AD1 in the nondominant eye.
Methods
This prospective, nonr...
Cross-linking (CXL) é o processo de formação de ligações covalentes intra e intermoléculas do colágeno do estroma corneano. Estudos tem demonstrado que o CXL foi capaz de estabilizar o ceratocone e as ectasias pós-refrativas por um período de 1 a 5 anos após o tratamento. Controvérsias permanecem no procedimento e nas suas variações técnicas. O pre...
"Quem elegeu a busca não pode recusar a travessia" (Guimarães Rosa) Segundo estimativas da Organização Mundial de Saúde (OMS), 285 milhões de pessoas, do mundo inteiro, têm deficiência visual (DV) e destas 39 milhões são cegas. As populações pobres e os grupos de idosos são os mais afetados: 82% das pessoas cegas e 65% das pessoas com cegueira mode...
Pterygia are usually benign lesions that do not require specific treatment. It is a fibrovascular growth onto the nasal side of the cornea. It's cause has not been fully elucidated yet, but seems to be related to long -term ultraviolet ray exposure. When symptoms are not controlled with conservative treatment surgery is considered, but the recurren...
A prevalência da miopia vem aumentando significativamente em todo o mundo ao longo das últimas décadas e é hoje uma das principais causas de deficiência visual, globalmente. Para enfrentar este grave e relevante problema de saúde pública, a comunidade oftalmológica, conta hoje, com o uso do colírio de atropina na concentração de 0,01% (1 gota diári...
Mulher branca de 40 anos, com diabetes tipo 1 controlado, apresentou perda visual de percepção luminosa no olho direito, imediatamente após cirurgia de catarata sem complicações. A paciente havia se submetido a uma vitrectomia 10 anos antes, devido a um descolamento de retina causado pelo diabetes. O uso de lidocaína intracameral sem conservantes e...
OBJETIVO: Comparar a eficácia do rastreamento visual com tabela optométrica de Snellen com o rastreamento refrativo com o SpotTM Vision Screener na detecção de fatores causadores de ambliopia em uma população de pré-escolares com 4-6 anos de idade. MÉTODOS: Foram submetidas a rastreamento visual 97 crianças pré-escolares matriculadas em creches mun...
O uso intracameral de antibiótico no final da cirurgia da catarata, em comparação com o uso tópico de antibiótico no pré e/ou pós-operatório, reduz significativamente o risco de endoftalmite pós-cirúrgica. O uso profilático desse regime terapêutico já é prática corrente na Europa e em número muito expressivo de países de outras regiões do mundo. Nã...
No Brasil, a maior barreira para o uso intracameral de antibiótico profilático rotineiro no final da cirurgia de catarata é a falta de uma preparação comercial de antibiótico para uso intracameral aprovada pela Agência Nacional de Vigilância Sanitária (ANVISA). O Grupo de Revisão da Literatura da Sociedade Brasileira de Catarata e Cirurgia Refrativ...
Objetivo: Apesar de a análise vetorial ser amplamente utilizada na literatura, tanto para a descrição de características, como na análise de mudanças no astigmatismo, poucos são os artigos que apresentam a racionalidade do método. Em nossa revisão, apresentamos os pontos mais importantes dos métodos propostos por Alpins e por Thibos. Métodos: O Pub...
Objetivo: Realizou-se estudo clínico prospectivo para verificar se há associação da assimetria do acometimento corneano no ceratocone com a posição preferencial de dormir. RESULTADOS: Todos os participantes foram submetidos ao questionário para avaliação da posição preferencial de dormir. Classificou-se como "olho dependente" o olho posicionado inf...
Purpose:
To compare the optical performance and visual outcomes between two diffractive multifocal lenses: AMO Tecnis® ZMB00 and AcrySof® ReSTOR® SN6AD1.
Methods:
This prospective, non-randomized comparative study included the assessment of 74 eyes in 37 patients referred for cataract surgery and candidates for multifocal intraocular lens implants...
Pterygium is a benign lesion usually growing from the nasal side of the conjunctiva onto the cornea. Most cases of pterygium does not cause problem or requires specific treatment. The exact cause of pterygium is not clear yet, but some factors are pointed as causes, being the most important the long term ultraviolet ray exposure. Pterygium surgery...
OBJECTIVE:
The purpose of this study was to evaluate the accuracy of Spot Vision ScreeningTM as an autorefractor by comparing refraction measurements to subjective clinical refractometry results in children and adult patients.
METHODS:
One-hundred and thirty-four eyes of 134 patients were submitted to refractometry by Spot and clinical refractomet...
Objetivo: Avaliar se a adaptação de lente de contato influencia a progressão do ceratocone. Método: revisão sistemática da literatura através das bases de dados Medline, Embase, Lilacs/Scielo, Cochrane Library até abril de 2015. Resultados: os resultados desta revisão basearam-se em dados de oito estudos. Conclusão: não há evidências que comprovem...
Os erros de refração não corrigidos são a principal causa de baixa de visão e, depois da catarata, é a segunda mais importante causa de cegueira. No Brasil a maioria da população não tem acesso a serviços oftalmológicos e tratamentos, sendo fundamentais os programas de triagem ou rastreamento visual. Triagem baseada em instrumento é rápida, não é d...
Background:
Air pollution is one of the most environmental health concerns in the world and has serious impact on human health, particularly in the mucous membranes of the respiratory tract and eyes. However, ocular hazardous effects to air pollutants are scarcely found in the literature.
Design:
Panel study to evaluate the effect of different l...
Purpose:
To evaluate the changes of corneal biomechanical after femtosecond laser – assisted cataract and to compare the parameters derived by Corvis ST between standard phacoemulsification and femtosecond laser – assisted in cataract surgery
Methods:
This is a prospective study. 151 eyes of 127 patients were under went cataract surgery. 75 eyes o...
A terminologia a ser adotada pelos profissionais da área de reabilitação da baixa visão e também de assuntos pertinentes à atuação de profissionais e serviços é de suma importância para: colaborar nas diretrizes de ações voltadas para a inclusão da pessoa com deficiência visual; colaborar com a atuação profissional; disseminar o “padrão-ouro” de at...
Este vídeo mostra uma complicação em uma cirurgia refrativa a laser com laser de femtosegundo IntraLase FS 60. Após realizar a cirurgia sem intercorrências no primeiro olho, começa a cirurgia no segundo olho. Perceba que nos dois procedimentos não foi utilizado aqui um campo estéril descartável para ajudar a manter as pálpebras abertas e separar os...
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Objetivo: Avaliar se a realização de LASIK e PRK de maneira bilateral simultânea é tão segura quanto a sua realização monocular sequencialmente em dias difer...
To compare the efficiency of surgical procedures using three phaco tip designs in torsional phacoemulsification using the bevel-down technique.
In this prospective, comparative, masked study, patients were randomly assigned to have torsional coaxial microincision cataract surgery using the mini-flared 45-degree Kelman tip, reversed mini-flared 30-d...
To determine the efficacy of tranilast as an adjunctive therapy in conjunctival autograft.
Twenty-nine patients were randomly allocated to the Tranilast Group (n=15) or the Control Group (n=14). The Tranilast Group received a subconjunctival injection of 0.5% tranilast 30 days prior to surgery. Conjunctival autograft was performed in both groups us...
The recognition of the need to follow the constant and profound changes in the field of medical information has inspired the CBO to create a new scientific journal, e- Oftalmo.CBO. Information technology has been increasing rapidly, improving our quality of life in various areas, whether professional, personal, or governmental. Analogic technologie...
Objective: Evaluate the anatomical, refractive, and functional results of an innovative technique of deep anterior lamellar keratoplasty with a manual spatula and discuss if a bare Descemet is really necessary in DALK. Materials and Methods: We evaluated the results and examinations of 16 eyes frompatients who underwent deep anterior lamellar kerat...
To provide a reliable, validated, and culturally adapted instrument that may be used in monitoring dry eye in Brazilian patients and to discuss the strategies for the enhancement of the cross-cultural adaptation and validation process of a self-report measure for dry eye.
The cross-cultural adaptation process (CCAP) of the original Ocular Surface D...
The corneal transplantation (CT) is the most commonly performed type of transplant in the world and the Eye Banks are organizations whose capture, evaluate, preserve, store and distribute ocular tissues. With the evolution of surgical techniques and equipment for CT, the BOs had to evolve to keep up with these requirements. This evolution goes from...
Purpose To compare the anti-inflammatory efficacy of ketorolac of tromethamine 0.4% and nepafenac 0.1% eye drops for prophylaxis of cystoid macular oedema (CME) after small-incision cataract extraction.
Methods Patients were assigned randomly to three groups. Group 1 patients received a topical artificial tear substitute (placebo); group 2 received...
Purpose: To measure and compare size and shape parameters of femtosecond laser capsulotomy with manually continuous curvilinear digital guided capsulorhexis (CCC) and their refractive outcomes. Methods: Laser capsulotomies in 40 eyes of 40 patients were performed using LenSx femtosecond laser device (Alcon, Forthworth, US) and its results were comp...
Some intriguing concepts of visual optics cannot be explained by ray tracing. However, they can be clarified using wavefront formalism. Its main advantage is in the use of the concept of vergence, which is very helpful in interpreting the optical phenomena involved in the neutralization of the ametropias. In this line of thinking, the major role of...