Milan NemyCzech Technical University in Prague | ČVUT · Department of Cybernetics and Robotics
Milan Nemy
PhD
Post-doctoral researcher at CTU & KI
About
10
Publications
1,246
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116
Citations
Introduction
Additional affiliations
September 2017 - present
Position
- PhD internship
Description
- Alzheimer's disease, Diffusion Tensor Imaging, Cholinergic System
February 2017 - present
Position
- PhD Student
Description
- PhD in biocybernetics and artificial intelligence with the main focus on digital image processing and data mining in Alzheimer's disease.
September 2014 - January 2017
Publications
Publications (10)
Previous studies have shown that the cholinergic nucleus basalis of Meynert and its white matter projections are affected in Alzheimer’s disease dementia and mild cognitive impairment. However, it is still unknown whether these alterations can be found in individuals with subjective cognitive decline, and whether they are more pronounced than chang...
Objectives
Several pathological processes might contribute to the degeneration of the cholinergic system in aging. We aimed to determine the contribution of amyloid, tau, and cerebrovascular biomarkers towards the degeneration of cholinergic white matter (WM) projections in cognitively unimpaired individuals.
Methods
The contribution of amyloid an...
The integrity of the cholinergic system plays a central role in cognitive decline both in normal aging and neurological disorders including Alzheimer’s disease and vascular cognitive impairment. Most of the previous neuroimaging research has focused on the integrity of the cholinergic basal forebrain, or its sub-region the nucleus basalis of Meyner...
Background:Dementia with Lewy Bodies (DLB) often presents with cholinergic degeneration and varying degrees of cerebrovascular disease (CVD). Radiological methods for assessing cholinergic degeneration in DLB are limited. We investigated the potential of the radiological Cholinergic Pathway Hyperintensities Scale (CHIPS) in identifying CVD-related...
Background
Subjective cognitive decline (SCD) is topic of mayor interest when identifying individuals at risk for future cognitive impairment and dementia. The degeneration of the cholinergic system is linked to the onset of cognitive symptoms in mild cognitive impairment (MCI) and dementia. Yet, it is uncertain whether the neurodegeneration of the...
Background
Neurodegeneration of cholinergic pathways may be present in individuals with subjective cognitive decline (SCD). However, variability between SCD individuals in the integrity of cholinergic pathways needs to be elucidated. Our objective was to determine characteristics of neurodegeneration of cholinergic pathways in different SCD subtype...
Background
To determine the contribution of amyloid pathology and tau pathology in combination with cerebrovascular pathology, towards the neurodegeneration of the cholinergic white matter projections.
Method
We included a sample of 203 cognitively unimpaired individuals derived from the H70 Gothenburg Birth Cohort Studies (all of them 70-years-ol...
Systém VENT-CONNECT je nová telemedicínská aplikace, která umožňuje vzdálené sledování obrazovek plicních ventilátorů a monitorů vitálních funkcí, jejichž datové výstupy nejsou přímo připojeny do nemocničního informačního systému. Systém umožňuje lékařům častější kontrolu parametrů umělé plicní ventilace u pacientů a tím i přesnější nastavení param...
Background
Recent advances in the neuroimaging field have rekindled the interest for the human cholinergic system. As the widespread projections from the basal forebrain to the cortex play an important role in learning, memory and other cognitive processes that are significantly impaired in disorders such as Alzheimer’s disease, Dementia with Lewy...
