Milan Breberina

• Dr sc. Professor of Surgical Oncology
• Head of Department at Retired at University of Novi Sad, Faculty of Medicine Novi Sad

The present study was designed to investigate whether there is a difference in the anastomotic leakage rate (AL) between the single stapling (CSA) and double stapling (DSA) anastomosis techniques. One hundred consecutive rectal cancer patients who underwent rectal resection with primary anastomosis were enrolled in this study. The overall rate of c...

Introduction: In the mid-twentieth century, the health care of women and children was inadequate in the post-war Yugoslavia, including the city of Novi Sad, due to the severe post-war reality: poverty in the devastated country, shortage of all commodities and services and especially of medical supplies, equipment and educated staff. OUT-OF-HOSPITA...

Following the shift in therapy of tuberculosis in the mid-19th century, by the beginning of the 20th century numerous tuberculosis sanatoria were established in Western Europe. Being an institutional novelty in the medical practice, sanatoria spread within the first 20 years of the 20th century to Central and Eastern Europe, including the southern...

Morphological changes in adipose tissue reflect functional disorders that correlate with cardiometabolic complications of obesity. The metabolic risks vary among the obese individuals. Furthermore, normal-weight individuals are not necessarily metabolically healthy. Therefore, the aim of this study was to analyze morphological characteristics of th...

Background: Colorectal carcinoma is the most frequent malignant disease of the abdomen. Only radical surgical treatment of the patients provides cure and good prognosis. Our aim was to find out the frequency of certain surgical procedures in the therapy for rectal carcinoma and survival rate of the patients compared to the applied surgery and clini...

The basis of complete mesocolic excision represents the continuation and the conceptual idea of the total mesorectal excision of rectum (TME) which was described and promoted by R. J. Heald in 1983, and the point is to make the excision of the contaminated portion of the colon with the tumor in his visceral (embryonic) sheath without any damages of...

Preoperative staging of rectal cancer is considered essential to select patients adequately for different therapeutic regimes. The aim of the present study was to evaluate the accuracy of endorectal ultrasonography in preoperative staging of rectal cancer. Fifty rectal cancer patients (31 men, 19 women) underwent endorectal ultrasonography with a 7...

The aim of our study was to determine the accuracy of endorectal ultrasonography (ERUS) in staging locally advanced rectal cancer after preoperative neoadjuvant chemoradiation and to point out the most common reasons for false interpretation. Forty-four patients with locally advanced rectal cancer received neoadjuvant chemoradiation followed by rad...

Treatment of rectal cancer, which includes periodic evaluations, may lead to earlier identification of recurrent local infiltration. Differentiation between local recurrence and other post radiation changes is frequently rather difficult. Pelvic MR examination was performed in 30 patients (20 men, 10 women) at the Institute of oncology, Sremska Kam...

The principal role of sentinel lymph node (SLN) sampling and ultrastaging in colon cancer is enhanced staging accuracy. The utility of this technique for patients with colon cancer remains controversial. This multicenter randomized trial was conducted to determine if focused assessment of the SLN with step sectioning and immunohistochemistry (IHC)...

In the article are described goals, methods and functions of "Stoma center" as a unit at the surgiocal ward.

The role of circulating TGF-beta(1) in prognosis of breast cancer (BC) was investigated with an intention to define TGF-beta(1)-dependent high risk and low risk subsets of patients. Fifty three BC patients of all clinical stages and 37 healthy donors (HD) were analyzed for plasma TGF-beta(1) by the TbetaRII receptor-based Quantikine TGF-beta(1) ELI...

Endorectal ultrasonography is valuable method for accurate local staging of rectal cancer. Precise evaluation of tumor stage is essential for optimal therapy planning in patients with rectal cancer. Furthermore, it has great influence on the resectability and the risk of recurrence following resection. Endorectal ultrasonography has become the most...

olorectal cancer is the fourth most common type of cancer worldwide yet there continues to be controversy and confusion regarding the best methods and techniques for its diagnosis and management. The treatment of rectal carcinoma is mainly determined by its local extension. Preoperative staging of rectal carcinoma can be assessed by different metho...

Background: The study shows operative results and complications occuring in the first 30 days after total gastrectomy because of stomach cancer. Materials and methods: Retrograde analysis was performed using medical documentation and histologic findings of 76 patients after total gastrectomy done between 1990 and 1997. Mortality and postoperative c...

The aim of this study was to present indications, contraindications, preoperative menagement and operative treatment of patients with gastric cancer. The principles of operative surgery for gastric cancer were highlited and distinctions between operative procedures were underlined.Medical documentation of two hundred and five patients consecutively...

1.1. Investigation of the mechanism of renal ammoniagenesis revealed that the Km of phosphate-dependent glutaminase (l-glutamine amidohydrolase, EC 3.5.1.2) for glutamine was significantly decreased, whereas V was increased if the mitochondria from both normal and acidotic rats were suspended in a hypotonic medium. These and other data indicate tha...