Mikko Herrala

Mikko Herrala
University of Eastern Finland | UEF · School of Pharmacy

PhD

About

14
Publications
1,083
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
113
Citations
Introduction
I am working (1.9.2022-31.8.2025) in my Academy of Finland funded postdoctoral project: Genotoxicity Assessment and Comparison of Toxicity Mechanisms of Natural Anthraquinone Dyes. My main research methods are toxicological in vitro assays, which I have used to study (geno)toxicity of natural dyes, microplastics and electromagnetic fields.
Additional affiliations
November 2019 - present
University of Eastern Finland
Position
  • PostDoc Position
January 2019 - October 2019
University of Eastern Finland
Position
  • PostDoc Position
January 2014 - December 2018
University of Eastern Finland
Position
  • Researcher
Education
January 2014 - December 2019
University of Eastern Finland
Field of study
  • Environmental Science
September 2006 - June 2012
University of Eastern Finland
Field of study
  • Environmental Science

Publications

Publications (14)
Article
We investigated whether exposure to intermediate frequency magnetic fields (IF MFs) could induce or enhance genomic instability in primary astrocytes. Rat primary astrocytes were exposed to vertical or horizontal 7.5 kHz, 300 μT MF for 24 h. To study possible combined effects with known genotoxic agents, the cells were exposed for 3 h to menadione...
Article
We assessed genotoxic effects of intermediate frequency magnetic fields (MF) in vitro and in vivo. Rat primary astrocytes were exposed for 24 h to a 7.5 kHz MF at a magnetic flux density of 30 or 300 µT. Male C57BL/6 J mice were exposed continuously for 5 weeks to a 7.5 kHz MF at 12 or 120 μT, and blood samples were collected for the genotoxicity a...
Conference Paper
Health effects of electromagnetic fields have been studied mainly focusing on extremely low frequency magnetic fields and radio frequency fields. Less attention has been paid to intermediate frequency magnetic fields (IF MFs) even though number of applications is increasing and information on potential health effects is sparse. We are conducting a...
Article
Extremely low-frequency (ELF) magnetic fields have been classified as possibly carcinogenic, mainly based on rather consistent epidemiological findings suggesting a link between childhood leukaemia and 50–60 Hz magnetic fields from power lines. However, causality is not the only possible explanation for the epidemiological associations, as animal a...
Article
Purpose: We examined genotoxicity, co-genotoxicity and induced genomic instability (IGI) in primary astrocytes exposed to radiofrequency (RF) radiation. Materials and methods: Rat primary astrocytes were exposed to 872 MHz GSM-modulated or continuous wave (CW) RF radiation at specific absorption rates of 0.6 or 6.0 W/kg for 24 h. Menadione (MQ) and...
Article
Purpose: We investigated the feasibility of a large-scale epidemiological study on reproductive effects of intermediate frequency (IF) magnetic field (MF) exposure among cashiers working near electronic article surveillance (EAS) systems. Materials and methods: The study cohort included 4157 women who had worked as cashiers in supermarkets with EAS...
Article
Full-text available
Human exposure to intermediate frequency (IF) fields is increasing due to new applications such as electronic article surveillance systems, wireless power transfer and induction heating cookers. However, limited data is available on effects of IF magnetic fields (MF) on male fertility function. This study was conducted to assess possible effects on...
Article
Purpose: We tested the hypothesis that effects of 50 Hz magnetic fields (MFs) on superoxide levels and genotoxicity depend on the presence of blue light. Materials and methods: Human SH-SY5Y neuroblastoma cells were exposed to a 50 Hz, 100 µT MF with or without non-phototoxic level of blue light for 24 h. We also studied whether these treatments al...
Poster
In this study rat primary astrocytes were used to study genotoxic effects of 7.5 kHz magnetic field exposure at 30 or 300 µT by measuring DNA damage using the single cell gel electrophoresis (Comet) assay and flow cytometric micronucleus scoring. Results will be reported in the BioEM 2016 meeting.

Network

Cited By

Projects

Project (1)
Project
The project aims at a breakthrough in understanding mechanisms for biological effects of weak ELF MFs. The project builds on our previous findings indicating that ELF MFs enhance the effects of certain other physical and chemical agents, as well as a mechanism (MF effects on radical pairs) that plausibly enables detection of weak MFs at least in animal navigation. The novel innovation in this project is the hypothesis that MF effects on radical pairs, rather than affecting overall cellular oxidative processes, might more likely lead to marked effects when they occur in molecules (cryptochromes) that are key components in biological regulatory networks. Novel experiments will be performed to reveal causal relationships, by studying temporal order of the biological changes using fluorescent live cell imaging system equipped with an advanced MF exposure system. The project will also further examine our previous findings of genomic instability (GI) induced by ELF MFs in vitro and, for the first time, study whether ELF MFs can induce GI in haematopoietic organs in an in vivo model.