Mikel Izquierdo

Mikel Izquierdo
Universidad Pública de Navarra | UPNA · Department of Health Sciences

Professor

About

665
Publications
472,782
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22,902
Citations

Publications

Publications (665)
Article
Background: This systematic review with meta-analysis aimed to compare the changes caused by exercise interventions with those provoked by usual care on physical function biomarkers in older adults immediately after hospital discharge. Methods: Two independent authors performed a systematic search (PubMed, Scopus, Web of Science, and SciELO) of st...
Article
Full-text available
Immersion water sports involve long-term apneas; therefore, athletes must physiologically adapt to maintain muscle oxygenation, despite not performing pulmonary ventilation. Breath-holding (i.e., apnea) is common in water sports, and it involves a decrease and increases PaO 2 and PaCO 2 , respectively, as the primary signals that trigger the end of...
Article
Full-text available
The aim of the study is to evaluate whether exercise interventions are associated with improved glycaemic control in children and adolescents with type 1 diabetes mellitus (T1DM), and to examine its relationship with the characteristics of the intervention (i.e., type, intensity, length, and duration of the sessions). Eligible criteria were randomi...
Article
Immersion water sports involve long-term apneas; therefore, athletes must physiologically adapt to maintain muscle oxygenation, despite not performing pulmonary ventilation. Breath-holding (i.e., apnea) is common in water sports, and it involves a decrease and increases in PaO2 and PaCO2, respectively, as the primary signals that trigger the end of...
Article
Background: Backpacks are widely used by children to carry different objects and the literature supports that most backpacks contain excessive weight. To minimize the loading effects (i.e., ground reaction force), modified backpacks have been tested. However, the effects of elastics on shoulders straps are yet to be studied. Thus, the aim of this s...
Article
The purpose of this study was to summarize the evidence from randomized clinical trials on the effects of dance on fall risk in older adults through a systematic review with meta-analysis. Fall risk was assessed through timed up and go, Berg Balance Scale, or one-leg stand tests. Data are presented as mean differences for timed up and go test and s...
Article
Full-text available
Background/Objectives: Muscle ultrasound is a convenient technique to visualize normal and pathological muscle tissue as it is non-invasive and real-time. This technique is related to several physical performance parameters and body composition components in adults; however, this relationship remains unexplored in early aged. We aimed to evaluate t...
Article
It is known that muscle strength is associated with adverse health outcomes associated with cancer-related symptoms. The purpose of this study was to investigate the association between handgrip strength and cancer in frail oldest old. In this prospective cohort study, 81 nonagenarians and centenarians were included [mean age (SD): 94.2 (3.8) years...
Article
Background: The coronavirus disease 2019 (COVID-19) pandemic could have provoked undesirable harmful effects on movement behaviours among children. Objective: To compare levels of physical activity (PA), sedentary behaviour (SB), and sleep time in children prior to and during the COVID-19 pandemic (after the lock-down) and to determine the associat...
Chapter
This chapter provides a rationale for using exercise and physical activity for health promotion and disease prevention and treatment in older adults. Physical inactivity is a key factor contributing to the onset of muscle mass and function decline, which in turn appears to be a vital contributant to frailty. The chapter discusses the exercise in te...
Article
Full-text available
Background The increase in life expectancy has led to profound changes in disease prevention and health maintenance. Because of the impact of dysbiosis on the host's health, it is worth considering microbiome-targeted therapies to attenuate or delay age-related perturbations. Aim The aim of the present review was to systematically evaluate the imp...
Article
Background: Acute care hospitalization increases the likelihood of developing cognitive impairment and delirium in older adults. Objective: To summarize evidence about the effectiveness of exercise and physical rehabilitation interventions on the incidence of delirium and cognitive impairment in acutely hospitalized older patients. Methods: Re...
Article
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Background and Objectives: The prevalence of chronic diseases increases with age, and in octogenarian elderly, a cardiorespiratory test with gas analysis is more effective in determining the risk of mortality than applying the conventional risk factors. Materials and Methods: 25 untrained non-frail octogenarian subjects (four men) performed a subma...
Article
Full-text available
Background: Prospective and large studies indicate that high physical fitness levels during young are beneficial for health during adulthood. The aim of the study was to investigate the tracking of physical fitness components from childhood and/or adolescence to adulthood. Methods: Two authors systematically searched MEDLINE and Web of Science e...
Article
Full-text available
Aquatic exercise is being increasingly recommended for healthy individuals as well as people with some special health conditions. A systematic review with meta-analysis was performed to synthesize and analyse data on the effects of water-based training (WT) programs on health status and physical fitness of healthy adults and adults with diseases to...
Book
Full-text available
The second volume of the Research Topic entitled “Precision Physical Activity and Exercise Prescriptions for Disease Prevention: The Effect of Interindividual Variability Under Different Training Approaches” has been successfully completed, as expected. As stated in the preface to the first volume, this Research Topic was initially intended to addr...
Article
Background physical activity reduces frailty in community-dwelling older adults. How exercise influences frailty in hospitalised older adults requires additional investigation. Objectives (i) to examine the impact of an exercise intervention on frailty in older adults admitted to an acute care ward, and (ii) to determine the impact of baseline fra...
Article
Full-text available
Background: Physical exercise is an effective strategy for preserving functional capacity and improving the symptoms of frailty in older adults. In addition to functional gains, exercise is considered to be a cornerstone for enhancing cognitive function in frail older adults with cognitive impairment and dementia. We assessed the effects of the Vi...
Article
Background: Hospitalisation-associated disability due to reduced physical activity levels and prolonged bedrest episodes are highly prevalent in older adults. Objective: To assess the effect of gamified interventions on functional capacity in hospitalised older adults. Methods: A three-armed non-randomised controlled trial with two experimental int...
Article
Propose Obesity-related metabolic risk factors in adolescents with overweight/obesity may be associated with systemic low-grade inflammation, and therefore we investigated whether a 6-month exercise training altered markers of inflammation. Methods Secondary analyses of a randomized controlled exercise-based intervention trial (September 2017 to D...
Article
Full-text available
The second volume of the Research Topic entitled “Precision Physical Activity and Exercise Prescriptions for Disease Prevention: The Effect of Interindividual Variability Under Different Training Approaches” has been successfully completed, as expected. As stated in the preface to the first volume, this Research Topic was initially intended to addr...
Article
Full-text available
Silva, LM, Neiva, HP, Marques, MC, Izquierdo, M, and Marinho, DA. Short post-warm-up transition times are required for optimized explosive performance in team sports. J Strength Cond Res 36(4): 1134–1140, 2022—This study aimed to compare the effect of 3 different post-warm-up transition times (3, 10, and 17 minutes) on team sports performance. A ra...
Article
Identifying serum biomarkers that can predict physical frailty in older adults would have tremendous clinical value for primary care, as this condition is inherently related to poor quality of life and premature mortality. We compared the serum lipid profile of physically frail and robust older adults to identify specific lipid biomarkers that coul...
Article
Background There is a general lack of information about how insufficient physical activity impacts blood pressure and physical fitness in Latin-American ethnic minorities. Aims To describe the interactions between insufficient physical activity, blood pressure, and physical fitness outcomes in Latin-American schoolchildren of different ethnicity....
Article
Full-text available
Objective: To analyze the effects of 8 weeks of an active exergames training program on walking speed, static balance, timed up-and-go test, and sit-to-stand performance in older females. Methods: Two groups of participants were formed by block-design randomization as follows: (i) control group (n=12; age, 74.1±7.9 years); (ii) 8 week exergames tra...
Article
Full-text available
We sought to assess the residual effects (post 72-h training cessation) on fasting plasma glucose (FPG) and fasting insulin (FI) after 12-weeks of high-intensity interval training (HIIT), resistance training (RT), or concurrent training (CT) in women with insulin resistance (IR). We also aimed to determine the training-induced, post-training residu...
Preprint
Full-text available
Abstract Background: There is a general lack of information about how insufficient physical activity impacts blood pressure and physical fitness in Latin-American ethnic minorities. Aims: To describe the interactions between insufficient physical activity, blood pressure, and physical fitness outcomes in Latin-American schoolchildren of different...
Article
The present systematic review with meta-analysis sought to estimate the accuracy of different waist-to-height ratio (WHtR) cut-off ranges as risk indicators for cardiometabolic health in different populations of children and adolescents. Systematic searches were undertaken to identify studies in apparently healthy participants aged 3-18 years that...
Article
Objective: The HEPAFIT study was aimed at examining the impact of a 6‐month physical education intervention, considering various levels of exercise intensity, on hepatic fat and cardiometabolic health outcomes in adolescents with excess adiposity. Methods: Adolescents (n = 120), 11–17 years with excess adiposity by body fat >30%, were randomly ass...
Article
Full-text available
The aim of this study was to assess the extent to which adolescents with and without visual and hearing-related problems meet physical activity (PA) and recreational screen time (ST) recommendations in a representative Colombian sample. A total of 35,404 adolescents aged 13-17 years were included from the Encuesta Nacional de Salud Escolar (ENSE) (...
Article
Full-text available
Aims/hypothesis The aim of this work was to quantify racial/ethnic differences in risk for future diabetic complications and all-cause mortality by performing a meta-analysis of prospective studies. Methods A systematic search in PubMed and EMBASE was performed from inception to May 2021. Prospective cohort studies that reported HRs and associated...
Article
Full-text available
Background There is limited evidence on the role of an anti-/pro-inflammatory diet in the prevention of non-alcoholic fatty liver disease (NAFLD). We aimed (i) to assess the anti-inflammatory diet profile and its association with transient elastography parameters, including liver stiffness measurement (LSM) and controlled attenuation parameter (CAP...
Conference Paper
Full-text available
Background Due to the devastating impact of the anterior cruciate ligament (ACL) injury has on the female athlete´s career, anthropometrics and biomechanics-related risk factor screenings have been widely designed. However, the relation of aberrant movement patterns and other anthropometrical variables still remains controversial. Objective The ai...
Poster
This study framed within the APTITUDE project presents the results of the baseline evaluations prior to a multicomponent intervention in community patients. The objective is to promote skills related to five different domains (physical exercise, nutrition, psychosocial problems, prevention of cognitive impairment and medication review). The study i...
Article
Full-text available
Abstract: The main objectives of the present study were to describe the injury incidence and to analyze the anthropometric and physical characteristics of players from three high-level women's football teams. The present study involved 54 female football players (21.9 ± 4.9 years old) from three different teams competing in the Spanish Reto Iberdro...
Article
Full-text available
Background: The role of muscular fitness (as a protecting factor for an optimal immune system) and WBC count remains unclear. To the best of our knowledge, this is the first study to investigate the relationship between the total count of WBC and groups based on handgrip strength and body composition. The aim of this study was to elucidate the rel...
Article
Full-text available
Introduction: The inverse association between cardiorespiratory fitness and all-cause mortality in apparently healthy populations has been previously reported; however, the existence of this association among adults diagnosed with cancer is unclear. Aim: To determine the association between cardiorespiratory fitness and all-cause mortality in ad...
Article
To date, no meta-analytical study evaluating the benefits of resistance exercise (RE) intervention on muscular strength and power and functional capacity in acute hospitalized older adults was conducted. Then, to synthesize the emerging evidence on the effects of RE intervention on muscular strength and power and functional capacity in acute hospit...
Article
Full-text available
The purpose of the present study was to investigate effects of type of exercise on the muscle strength and functional performance gains for lower-body in older adults after heavy resistance training. Twenty untrained older adults volunteers (8 men and 12 women) were randomized and placed into two groups: multi-joint exercise—MJ (65 ± 6 years) and s...
Article
Full-text available
The human ageing process is universal, ubiquitous and inevitable. Every physiological function is being continuously diminished. There is a range between two distinct phenotypes of ageing, shaped by patterns of living - experiences and behaviours, and in particular by the presence or absence of physical activity (PA) and structured exercise (i.e.,...
Article
Background: The aims of this study was to assess the potential of sixteen anthropometric, body composition and endocrine indexes as predictors of high liver fat and determine the most appropriate cutoff points in US adolescents. Methods: A cross-sectional study was conducted on a population of 816 adolescents aged 12–17years. The FibroScan®502V2 de...
Article
Full-text available
The aim of this study was to determine whether handgrip strength attenuates the negative relationship between age and olfactory function in a representative US population sample 40years old and over. A cross‑sectional study was performed with 2861 adults from the US National Health and Nutrition Examination Survey NHANES (2013–2014). An 8‑item odor...
Article
Objective To determine the effects of interventions aimed at optimising the quantity and quality of physical education (PE) on cognition and academic performance in children and adolescents. Design A systematic review and meta-analysis. Data sources Studies from electronic databases from inception to 3 January 2021 were identified. Eligibility c...
Article
Full-text available
Background Cardiorespiratory fitness (CRF) is inversely associated with mortality in apparently healthy subjects and in some clinical populations, but evidence for the association between CRF and all-cause and/or cardiovascular disease (CVD) mortality in patients with established CVD is lacking. This study aimed to quantify this association. Meth...
Article
This editorial describes the potential pathophysiological involvement and clinical implications in HF of a group of molecules, known as myokines, which are secreted in skeletal muscle, and pays special attention to those aspects related to their direct myocardial impact.
Article
Objectives: To analyze the effects of a program composed of resistance training and nutritional interventions on functional capacity, maximal strength and power output after 2 years of follow-up including 2 periods of 16 weeks of intervention followed by several weeks of intervention cessation in frail patients with type 2 diabetes. Design: MIDPOW...
Article
Objectives: We aimed to determine whether the benefits of long (24 weeks) and short (4 weeks) training programs persisted after short (6 weeks) and long (14 weeks) periods of inactivity in elderly nursing home residents with sarcopenia. Design: Multicenter randomized trial. Intervention: The Vivifrail tailored, multicomponent exercise programme (h...
Article
Full-text available
Physical function (ie, aerobic capacity, gait speed, and muscle strength) has been proposed as a biomarker of healthy ageing, as it is predictive of adverse health events, disability, and mortality. The role of physical exercise as a therapeutic strategy for prevention of both disease and the associated decline in functional capacity has been empha...
Article
Full-text available
Background Physical activity has been associated with reduced risk of seven types of cancer. It remains unclear, however, whether muscle-strengthening activities also reduce cancer incidence and mortality. Methods PubMed, Embase, Web of Science and Scopus were searched from inception to March 2020. Summary hazard ratio (HR) and 95% confidence inte...
Article
Background: Handgrip strength (HGS) is an indicator of overall strength; therefore, individual HGS measurements should be interpreted using geographic region and ethnic group references. Aims: The aim of this study was to develop new normative values for absolute and relative HGS in the Colombian population after stratification by sex, age, body m...
Article
Purpose: This study aims to develop gender-specific operational equations for prediction of cardiorespiratory fitness in female footballers. Method: Forty-eight semi-professional female footballers performed an intermittent progressive maximal running test for determination of fixed blood lactate concentration (FBLC) thresholds. Relationships betw...
Article
Exercise interventions have been found safe in acutely hospitalized older adults in general and to attenuate the decline in functional and physical performance that is frequently induced by even short hospital stays. However, controversy exists as to the safety of initiating this type of intervention during hospitalization for patients admitted wit...
Article
BACKGROUND: Increasing evidence highlights the role of muscular strength as a protective factor for cardiometabolic health in adolescents. However, it is not known the relationship between liver enzyme concentrations, liver disease risk factors, and muscular strength among young populations. The aim of this study was to determine the association be...
Article
We aimed to determine the reference values to define an age-specific normal range of controlled attenuation parameter (CAP, a measure of liver steatosis) and liver stiffness measurement (LSM) values assessed by ultrasound-based transient elastography in adolescents without underlying liver disease. A total of 462 participants were included in this...
Article
Full-text available
There is evidence demonstrating the presence of functional compartmentalisation (FC) in some skeletal muscles. This means that the motor units (MU), grouped in certain areas of the muscle, show different levels of activation in comparison to those located in other zones. This has only been described in large muscles whose morphology proves the exis...
Article
There is emerging evidence that emphasizes RDW as an optimal prognostic biomarker for cardiovascular diseases. However, there is hardly any evidence of interventions that are capable of modifying RDW. Our aim was to investigate the association of RDW levels and the response to an individualized exercise program in hospitalized older adults. To our...
Article
Full-text available
Daily glucose variability is higher in diabetic mellitus (DM) patients which has been related to the severity of the disease. However, it is unclear whether glycemic variability display a random or specific pattern of oscillation. Thus, to determine the glycemic variability pattern, we measured and analyzed continuous glucose monitoring (CGM) data,...
Technical Report
https://blogs.bmj.com/bjsm/2021/03/06/vivifrail-a-multi-component-physical-training-program-to-prevent-weakness-and-falls-in-people-over-70-years/
Article
Marta, C, Alves, AR, Casanova, N, Neiva, HP, Marinho, D, Izquierdo, M, Nunes, C, and Marques, MC. Suspension vs. plyometric training in children's explosive strength. J Strength Cond Res XX(X): 000-000, 2021-The aim of this study was to compare the effects of different training programs, that is, 8 weeks of suspension training (ST) or plyometric tr...
Article
Concurrent training (CT) is an efficient strategy to improve neuromuscular function and cardiorespiratory fitness in older adults, which are factors of pivotal importance for the maintenance of functional capacity with aging. However, there is a lack of evidence about the effectiveness of power training (PT) as an alternative to traditional strengt...
Article
The aim of this review was to summarize the evidence from longitudinal studies assessing the effects induced by resistance training (RT) performed to failure (RTF) vs. not to failure (RTNF) on muscle strength, hypertrophy, and power output in adults. Three electronic databases were searched using terms related to RTF and RTNF. Studies were eligible...