
Mikel IzquierdoPublic University of Navarre | UPNA · Department of Health Sciences
Mikel Izquierdo
Professor
About
796
Publications
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Publications
Publications (796)
Objective
This study aimed to explore the association between handgrip strength, cardiometabolic risk (CMR) and body composition in youth with type 1 diabetes.
Methods
For this prospective cohort study, muscular fitness was assessed via handgrip test and relativised by weight, and body composition, evaluated through dual-energy X-ray absorptiometr...
We hypothesized that non-hospitalized patients with long COVID would benefit from structured exercise. In a randomized cross-over trial, we assessed the effects of a 6-week personalized PRT intervention, with a 5-day washout period between arms on cardiopulmonary fitness, muscular strength, long COVID symptoms, QoL, and emotional distress.
Background.
Outstanding exercise performance has been associated with an exacerbated vagal outflow. Nevertheless, during high-altitude hypobaric-hypoxia (HH), there is a baroreflex-dependent parasympathetic withdrawal and exercise performance deterioration. Notably, vagal control is pivotal in exercise performance, and exogenous oxytocin (OXY) admi...
BACKGROUND: In type 1 diabetes, telomere length (TL) may predict complications and could be influenced by glycaemic control and physical activity, but its relationship with physical fitness in youths remains unexplored. The aim of the study was to assess the association between physical fitness and TL in youth with type 1 diabetes, both at baseline an...
Background
Hospitalization exacerbates sarcopenia and physical dysfunction in older adults. Whether tailored inpatient exercise prevents acute sarcopenia is unknown. This study aimed to examine the effect of a multicomponent exercise programme on muscle and physical function in hospitalized older adults. We hypothesized that participation in a brie...
INTRODUCTION:
Physical function characteristics of cognitively-unimpaired (CU) older adults at high risk of dementia are not comprehensively described. Sex may have a role in the effect of physical performance on cognition. This study aims to describe the sociodemographic and clinical characteristics of CU older adults at risk of dementia, and to...
Introduction
Recent studies have suggested that sustained multidomain interventions, including physical exercise, may be beneficial in preventing cognitive decline. This review aims to assess the impact of prolonged physical exercise and multidomain strategies on overall cognitive faculties and dementia risk among community-dwelling older adults wi...
This study investigated the associations between preseason and in-season physical performance measures with external workload [global system positioning (GPS) data] in professional soccer players. Twenty-one players completed hamstring eccentric strength, countermovement jump (CMJ), 20-m sprint, and Yo-Yo intermittent recovery tests before (preseas...
Aims
This study sought to elucidate the interactions among physical activity (PA) patterns, mean glucose concentrations, and the incidence of nocturnal hypoglycemia events in children and adolescents with type 1 diabetes, examining the moderating influence of daily dosage on these associations.
Methods
Eighty-two participants aged 6 to 18 years (4...
The available evidence on the impact of specific non-pharmacological interventions on glycaemic control is currently limited. Consequently, there is a need to determine which interventions could provide the most significant benefits for the metabolic health of young individuals with type 1 diabetes mellitus. The aim of this study was to identify op...
Background: This study aimed to examine the effects of a six-week of concurrent training using high-intensity interval plus resistance training on flow-mediated dilation and pulse wave velocity in hypertensive, elevated blood pressure, or normotensive. A secondary goal was to analyze the inter-individual variability.
Methods: A randomized controlle...
BACKGROUND: Accumulating evidence supports the notion that dementia is a multifactorial condition with various risk factors and causes. The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) demonstrated that lifestyle interventions could confer cognitive benefits. Inspired by this, the GOIZ-ZAINDU (GZ) fea...
Background & aims: The utilization of non-invasive techniques for liver fibrosis and steatosis assessment has gained acceptance as a viable substitute for liver biopsy in clinical practice. This study aimed to establish normative data for the controlled attenuation parameter (CAP) and liver stiffness measurement (LSM) by age and gender, as well as...
Purpose: To identify the physical conditioning and functional injury screening characteristics of elite female soccer players. Methods: This review was prospectively registered (PROSPERO CRD4202346765). Searches were conducted in PubMed/MEDLINE, Cochrane Library, Scopus, and Web of Science (from inception in March to July 2023). Updated searches we...
Background and Objectives
Exercise may reverse functional decline in hospitalized older adults, but the optimal duration is unclear. This study examined the potential relationship between in-hospital multicomponent exercise program duration and changes in physical function, cognition, and muscle function to maximize exercise-related health benefits...
Background
To evaluate the progression of physical fitness (PF), basic motor competence (BMC), and executive function (EF) over one year in children aged 4–5 years at a health center.
Methods
In this longitudinal analysis, children’s BMC was evaluated using the MOBAK KG test for object and self-movement. The PREFIT Battery gauged PF through handgr...
The aim of this systematic review was to assess the effects of plyometric-jump training (PJT) on the physical fitness of youth with cerebral palsy (CP) compared with controls (i.e., standard therapy). The PRISMA 2020 guidelines were followed. Eligibility was assessed using the PICOS approach. Literature searches were conducted using the PubMed, Web...
Purpose:
This study investigated the impact of four weeks of age-dependent detraining on army soldiers' cardiorespiratory fitness and maximal and explosive strength.
Methods:
Fourteen volunteer tactical athletes participated, divided into two age groups (20 to 29 and 30 to 40 years). Before and after the detraining period, we assessed their anth...
BACKGROUND
Physical activity (PA) plays a crucial role in the early development of children and has a significant impact on various aspects of health.
OBJECTIVE
This study evaluated a 12-week supervised, multicomponent gamified exercise program aimed at increasing PA adherence in 5-year-old preschoolers, in accordance with the 24-hour movement beh...
Numerous studies have documented disparities in Physical Fitness (PF) between boys and girls. This cross-sectional study investigates if echo-intensity (EI) explains the relationship between sex and PF among children. The study cohort consisted of 497 children aged 4.0–10.9, including 288 boys and 209 girls. Anthropometric measures, including heigh...
Introduction
The use of new technologies presents an opportunity to promote physical activity, especially among young people with type 1 diabetes (T1DM), who tend to be less active compared to their healthy counterparts. The aim of this study is to investigate the impact of a personalized resistance exercise program, facilitated by the Diactive-1 A...
Postoperative delirium (POD) is a common neuropsychiatric complication in geriatric inpa- tients after hip fracture surgery and its occurrence is associated with poor outcomes. The purpose of this study was to investigate the relationship between pre- operative biomarkers in serum and cerebrospinal fluid (CSF) and the development of POD in older hi...
Postoperative delirium (POD) is a common neuropsychiatric complication in geriatric inpatients after hip fracture surgery and its occurrence is associated with poor outcomes. The purpose of this study was to investigate the relationship between preoperative biomarkers in serum and cerebrospinal fluid (CSF) and the development of POD in older hip fr...
Swimmer athletes showed a decreased ventilatory response and reduced sympathetic activation during peripheral hypoxic chemoreflex stimulation. Based on these observations, we hypothesized that swimmers develop a diminished cardiorespiratory coupling due to their decreased hypoxic peripheral response. To resolve this hypothesis, we conducted a study...
Background
Physical function profiles of older adults (≥ 60years) cognitively unimpaired but at high risk of dementia (CAIDE dementia risk score ≥6) have not been well described. The CAIDE index evaluates both modifiable, cardiovascular (CVRF), and non‐modifiable risk factors such as age, sex and educational level. The association of these factors...
Background
The FINGER study demonstrated the efficacy of a non‐pharmacological multidomain intervention to prevent cognitive decline in at‐risk older adults. After a successful pilot feasibility study, in Q3 2021 we launched the CITA GO‐ON study, inspired by FINGER methodology to demonstrate the efficacy of a risk factor and lifestyles multimodal i...
Introduction: Hip fractures are the most common fracture leading to hospitalization and are associated with high costs, mortality rates and functional decline. Although several guidelines exist for preventing new fractures and promoting functional recovery, they tend to focus on osteoporosis treatment and do not take into account the complexity of...
Aims
The aim of this study was to determine the global incidence of type 1 diabetes mellitus (T1DM) in children and adolescents under 20 years of age from 2000 to 2022.
Materials and Methods
Two reviewers searched three electronic databases (PubMed, Web of Science, and CINAHL) for studies published between January 2000 and November 2022. Pooled es...
Background
Bed rest during hospitalization can negatively impact functional independence and clinical status of older individuals. Strategies focused on maintaining and improving muscle function may help reverse these losses. This study investigated the effects of a short‐term multicomponent exercise intervention on maximal strength and muscle powe...
Background and aims:
The worldwide aging population is expanding, with more individuals living into their 80s. Physiological functions decline gradually with age, compounded by sedentary lifestyles. Incorporating physical activity into daily routine is crucial for maintaining independence. This study aimed to assess a periodized high-intensity aer...
Objetivos
La actividad física (AF) y la función física (FF) podrían tener un efecto modulador de la patogenia de la enfermedad de Alzheimer (EA). El objetivo es explorar la relación entre AF o FF y biomarcadores de LCR en estadios precoces de la enfermedad.
Material y métodos
Estudio transversal con reclutamiento desde una cohorte de base poblaci...
Background
Power training (PT) has been shown to be an effective method for improving muscle function, including maximal strength, measured by one-repetition maximum (1RM), and power output in older adults. However, it is not clear how PT intensity, expressed as a percentage of 1RM, affects the magnitude of these changes. The aim of this systematic...
Osteoporosis is a skeletal disease that can increase the risk of fractures, leading to adverse health and socioeconomic consequences. However, current clinical methods have limitations in accurately estimating fracture risk, particularly in older adults. Thus, new technologies are necessary to improve the accuracy of fracture risk estimation. In th...
Background
Upper-body plyometric training (UBPT) is a commonly used training method, yet its effects on physical fitness are inconsistent and there is a lack of comprehensive reviews on the topic.
Objective
To examine the effects of UBPT on physical fitness in healthy youth and young adult participants compared to active, specific-active, and pass...
To investigate the effects of two different exercise interventions on cost of care, functional capacity, falls occurrence, muscle strength, and executive function in institutionalized oldest old.
A pilot study of a randomized clinical trial investigating 12 months of two exercise interventions compared to a usual care group in oldest old residents...
Importance
Although benefits have been reported for most exercise modalities, the most effective exercise approaches for reducing insulin resistance in children and adolescents with excess weight and the optimal exercise dose remain unknown.
Objective
To compare exercise training modalities and their association with changes in insulin resistance...
Objective:
This study aimed to (1) characterize cardiometabolic factors in self-reported hip and knee osteoarthritis (OAD) across four body composition phenotypes defined by muscle mass and adiposity, and (2) associate risk factors with diabetes and hypertension (HTN).
Methods:
A cross-sectional analysis of the Chilean National Health Survey 201...
Cancer mostly affects older adults, causing a wide variety of diagnostic and therapeutic dilemmas. One of the most important moments in cancer patients is the hospitalization period, in which older patients usually remain bedridden for many hours and this may lead to the appearance of sarcopenia and disability.
We present the research protocol for...
There is limited information regarding heart rate (HR) response from predictive formulae and actual exercise tests between arterial hypertension (HTN) and normotensive adults, as well as about vascular similarities or differences between samples of different blood pressure control. This study aimed 1) to describe and compare the HR during exercise...
Introduction: lack of physical activity and sedentary lifestyles in children are associated with increased adiposity, low cardiovascular fitness, and risk of cardiovascular disease. However, meeting physical activity recommendations is associated with improvements in mental health, decreased anxiety and depression, and better health habits. Objecti...
Most of the evidence on physical activity for maintaining a healthy weight in adolescents is based solely on aerobic physical activity alone, with little attention given to the muscle strength component. This study aimed to investigate the associations between aerobic activities and muscle‐strengthening activities (MSA) and overweight/obesity among...
Profile determination in field hockey is critical to determining athletes' physical strengths and weaknesses, and is key in planning, programming, and monitoring training. This study pursued two primary objectives: (i) to provide descriptive data on sprinting, deceleration, and change of direction (COD) abilities and (ii) to elucidate the mechanica...
Purpose:
Hip fracture is a public health problem worldwide. Traditional prognostic models do not include blood biomarkers, such as those obtained by proteomics. This study aimed to investigate the relationships between serum inflammatory biomarkers and frailty in older adults with hip fracture as well as adverse outcomes at one and three months af...
Background
Evidence suggests that movement patterns, including physical activity, sedentary behavior, and sleep duration, throughout a 24-h period, have a significant impact on biological processes and health outcomes for both young and adult populations. However, 80% of adolescents worldwide are not sufficiently active, and many children do not me...
Background
Basic motor competencies (BMC) play a vital role in child development and are a primary focus of physical education. However, there is a lack of research on BMC in preschool-aged children, making this study particularly significant. The present study aims to examine the relationship between BMC and physical fitness components in Spanish...
Quantitative diagnostic ultrasound has been proposed as a way to characterize muscle structure, but there is a lack of normative data for children. This study aims to establish age-specific normal ranges for echo-intensity (EI), cross-sectional area (CSA), muscular thickness (MT), and subcutaneous adipose thickness (SAT) values of the rectus femori...
Anthropometric characteristics, including body size, shape, and composition, can have a significant impact on sports performance due to their influence on various physiological and biomechanical factors. However, limited research has been conducted on the anthropometric characteristics of highly trained throwing para-athletes. The purpose of this s...
Background:
The World Health Organization proposed the concept of intrinsic capacity (IC; the composite of all the physical and mental capacities of the individual) as central for healthy ageing. However, little research has investigated the interaction and joint associations of IC with cardiovascular disease (CVD) incidence and CVD mortality in m...
Background:
The inclusion of electrocardiogram (ECG) in medical examinations for sports practice serves as a valuable tool for identifying potential life-threatening conditions during physical exercise. However, its applicability in young individuals remains a subject of controversy, primarily due to relatively high rates of false positives and th...
Delirium is a neuropsychiatric syndrome associated with increased morbidity and
mortality in older patients. The aim of this study was to review predictive biomarkers
of delirium in older patients to gain insights into the pathophysiology of this
syndrome and provide guidance for future studies. Two authors independently
and systematically searched...
Objective: Hip fracture is a public health problem worldwide. Traditional prognostic models do not include blood biomarkers, such as those obtained by proteomics. In this prospective cohort study, we aimed to explore the role of a targeted proteomic approach in better characterizing frailty in older adults with hip fractures.
Moreover, we sought to...
Objective: The clinical screening of hip fracture risk is complicated due to the limitations of the reference tools (i.e., bone turnover markers, BMD, FRAX) but with new biomarkers could provide better information for this risk. The present study described emerging biomarkers of the risk of hip fractures with different biomarkers in serum and compa...