Mihai Florin Marcu

University of Oradea · Department of Psycho-Neuroscience and Recovery

Aging is the most prominent risk factor for late-onset Alzheimer’s disease. Aging associates with a chronic inflammatory state both in the periphery and in the central nervous system, the evidence thereof and the mechanisms leading to chronic neuroinflammation being discussed. Nonetheless, neuroinflammation is significantly enhanced by the accumula...

(1) Background: Fish is a good source of protein, iron, and zinc, which are key nutrients for infant growth and development, as well as a source of energy for adults and the elderly. Due to mercury contamination in both the terrestrial and aquatic environments, there is a risk that considerable levels of mercury will be ingested by the population,...

Poor air quality inside museums can have a double effect; on the one hand, influencing the integrity of the exhibits and on the other hand, endangering the health of employees and visitors. Both components can be very sensitive to the influence of the internal microclimate, therefore careful monitoring of the physical parameters and pollutants is r...

The gastrointestinal (GI) tract is one of the most studied compartments of the human body as it hosts the largest microbial community including trillions of germs. The relationship between the human and its associated flora is complex, as the microbiome plays an important role in nutrition, metabolism and immune function. With a dynamic composition...

Stroke is the second cause of disability worldwide as it is expected to increase its incidence and prevalence. Despite efforts to increase the number of patients eligible for recanalization therapies, a significant proportion of stroke survivors remain permanently disabled. This outcome boosted the search for efficient neurorestorative methods. Ste...

Alzheimer’s disease (AD), the most common form of dementia, has increasing incidence, increasing mortality rates, and poses a huge burden on healthcare. None of the currently approved drugs for the treatment of AD influence disease progression. Many clinical trials aiming at inhibiting amyloid plaque formation, increasing amyloid beta clearance, or...

Rheumatoid arthritis (RA) is a chronic multifactorial disorder of autoimmune etiology with a complex pathophysiological mechanism that is not yet fully elucidated. RA pharmacotherapy includes active molecules of chemical or biological nature that offer symptomatic relief and a slowing of progression, but still in a context of incurability. Therefor...

(1) Background: Due to its frequency and possible complications, low back pain (LBP) has a high social impact, it is a common problem of the active population and the second reason for visiting a physician. In patients with lumbar disc protrusion (LDP), one of the most common causes of LBP, the nucleus pulposus bulges against the disc and then prot...

Background and objectives: Due to its frequency and possible complications, hip arthrosis or hip osteoarthritis (hip OA) has a high social impact, its advanced stages eventually leading to irreversible lesions involving major complications or surgery. In the early stages, conservative treatment plays a key role in the prophylaxis of complications a...

Sepsis-induced myocardial dysfunction (SIMD) is one of the major predictors of morbidity and mortality of sepsis. A high percentage of patients with SIMD develop a status similar to cardiogenic shock. A high level of bacterial lipopolysaccharide (LPS) associated with an overexpression of CD14 acts as the trigger for the release of a broad spectrum...

Low back pain is a common problem in the active population, and the second reason for visiting a physician. In patients with lumbar disc protrusion, the nucleus pulposus bulges against the disc and the latter protrudes into the spinal column, but the annulus fibrosus remains intact. The purpose of this study was to prove that starting an early comp...

(1) Background: Hip arthroplasty (HA) is a surgery that replaces the damaged hip joint with an artificial implant called a hip prosthesis. The increase in life expectancy correlated with the population aging level, to which the increase in the number of prosthetic interventions among the young population is added, translates to the imperative need...

Monitoring the indoor microclimate in old buildings of cultural heritage and significance is a practice of great importance because of the importance of their identity for local communities and national consciousness. Most aged heritage buildings, especially those made of wood, develop an indoor microclimate conducive to the development of microorg...

The heritage woven objects could be analyzed for defects hidden to the naked eye using non-invasive and non-destructive ultrasonography techniques. Ultrasonography is able to offer information about altered areas, such as gasps, interruptions, discontinuances, narrowed areas, fiber breaks, different densities of the material, defects caused by natu...

Osteoporosis, a major skeletal disorder characterized by decreased bone mass, predominantly affects women and has a major impact on public health. Fractures due to bone fragility are the most important complications of osteoporosis. The main objectives of the optimal management of osteoporosis are to increase muscle strength and strengthen bones, r...

Poor air quality inside museums is one of the main causes influencing the state of conservation of exhibits. Even if they are mostly placed in a controlled environment because of their construction materials, the exhibits can be very vulnerable to the influence of the internal microclimate. As a consequence, museum exhibits must be protected from p...

Objective. Our main goal in this study was to determine whether or not in addition to classical and biological treatments, rehabilitation treatment had any benefit in the evolution of the psoriatic arthritis. Material and methods. We evaluated two groups of patients, classified according to their basic therapies, namely classical treatment of psori...

The studied textile object is a traditional female embroidered peasant shirt, old of about 100 years, from a private collection. Bacteria and fungi were assessed through specific methods. Determination of most common fungi and yeasts, consists in: Penicillium spp., Cladosporium spp., Fusarium spp., Alternaria spp. and Candida spp. These can contrib...

It is important to investigate the indoor air quality, the microbial concentration of indoor air and surfaces for preserving the cultural heritage. In what regards the microclimate inside the historic monument, the wooden church, the temperature and relative humidity were monitored using the thermo-hygrometer with data function logger “Klimalogg Pr...

Aim: The paper focuses on the investigations upon some aged textiles, from Romania. Fungi by their enzymatic action have an important role in the degradation of ethnographic goods and pose a potential risk to the health of museographers and visitors. Methodology: Fungal contamination was determined using the conventional techniques of open plates...

This study is an attempt to monitor the indoor microclimate and the microbiological contamination of some indoor objects inside a wooden Orthodox church. Standard microbiological techniques were used for the isolation and identification of the fungi present in the dust of the superficial surface of the paintings chosen to be investigated for biodet...

The high rate of children becoming ill during school periods as opposed to during school holidays has forced authorities associated with the educational system and labour medicine to carry out regular checks in schools and to assign hygienization tasks. Air quality reports, otherwise completely absent from schools, have been requested. Students hav...

Digitization of cultural heritage, has started to play a major role in sustainability; also, old maps investigations can be a valuable source of information. These should be carefully handled by archive workers and those who are studying them, because mycological content can increase both human health and environmental problems. These, together wit...

The article monitors the implications of different treatment strategies upon the quality of life for rheumatoid arthritis patients following the HAQ and VAS scale throughout 12 months of study on 136 patients

The present paper is analyzing the quality of the air (temperature, humidity, light, contamination with fungi) inside the Museum House from Salacea, Bihor county, and the influence of such factors on textile materials that are exposed inside it in the context of the need to protect the heritage elements and in order to diminish the risks related to...

Natural protected areas are suitable for outdoor sport and leisure activities, where the geographic context allows it, which are not generating a significant negative environmental impact. One of the proposed tourist routes in the study protected area, on which the tests were performed, was completed in four modes: walking, running, cycling and nor...

The presence of microorganisms in indoor air is a serious problem with a great impact in the field of health protection and environmental engineering. The people exposed to high concentrations of microbes in the air can develop frequently allergies. Young people, including students, constitute a large group of allergy sufferers. For that reason det...

The mechanical vibrations’ therapy is widely used as a non-conservative and safe physical method for patients diagnosed with osteoporosis, postmenopausal women and sportsmen training, also during athletes’ recovery and rehabilitation phase. This paper has the main goal in assessing the benefic effects of whole-body-vibration (WBV) therapy applied t...

Osteoporosis is a systemic skeleton disease, characterized by a low bone mass and micro-architectural deterioration of bone tissue with consecutive increasing of fragile bones and susceptibility of fractures. Risk facture, advanced ages, family history, rheumatoid arthritis, low calcium intake, physical inactivity, and low body weight can lead to t...

One wildly used method to reduce and control the noise pollution in green city’s buildings is using sonic-absorbent panels. Their applications can be multiple, such as the insulation of buildings, acoustic barriers and fences along the highway or in front of supermarkets, hospitals and other public buildings. This paper presents a method for testin...

Osteoporosis (OP) represents the most common metabolic bone disease, characterized by the shrinkage in bone mass and the destruction of bone quality, thus conferring a higher risk for micro-fractures and injuries. The goal of treatment in OP is to grow-up the bone mineral density of the skeleton and to increase resorption of formed bone, due to imp...

Solving the acoustical problem and improving the impact indoor environmental quality represents a priority for many researchers and manufacturers of materials with a high noise reduction of coefficient rating. The paper presents a real solution for determination the sound-absorption coefficient of materials with acoustical properties from the gypsu...

The analysis and implementation of modern treatments for the patients diagnosed with osteoporosis, degenerative rheumatic affections and peripheral circulatory disorders have become a healthy priority for the society. These treatments have the goal to raise the bone mineral density of the skeleton, reducing joints pain and inflammation while improv...

The osteoporosis is characterized by the imbalance between the activity of the osteoblasts, the bone forming cells, and the osteoclasts, the cells that resorb the bone tissue, imbalance that favors the osteoclasts. As a conclusion, in the case of osteoporosis, for the same volume, the bone is less compact and more fragile. The objective of our stud...

Background: Osteoporosis, characterized by the decrease of bone mass and deterioration of bone tissue, is called the "silent disease" because rarefaction of bone structure is not accompanied by pain. World Health Organization (WHO) said on osteoporosis as a public health problem, the third in importance after heart disease and cancer. Physical exer...

The paper presents some aspects and practical solutions of weight bearing joints treatment for patients with osteoarthritis and following by the rehabilitation process, which has realized at Recovery Clinical Hospital of Felix Spa. A model of human body under applied and conjunction forces explains the damping and shocks into synovial joints from e...

The paper is presented a dynamic installation used for determination the elastic characteristics of gypsum materials, such as elasticity modulus-E, rigidity modulus-G, etc. This dynamic installation is composed from: mechanical device for application of axial force, cylindrical gypsum samples on which are fixed 2 strain gages, 2 bridges circuit typ...

Background: In chronic rheumatic diseases, traditional epidemiological measures of disease outcome reflect only the physical dimension of the disease and neglect the mental and social aspects. In recent years, there has been a great interest in quality of life measures that reflect physical, mental and social, dimensions together. This study was de...

Background: The arthroses are chronic artropathies that affect the peripherical or vertebral joints,being morphologically distinguished by regressive degenerative lesions of the joint hyaline cartilage, with subchondral bone modifications, and as well as of the synovial and the periarticular soft tissues also clinically by pain, limitation and defo...

The EU Norms about of protection environment, outside and inside ambient, and human health demands has lead at obtain of new materials on the base of airborne material, with high thermo and phonic‐absorbent properties, porous and lightweight. The α and β‐modeling gypsum plaster quality and lightweight depend on many factors as: fabrication process,...

The paper presents some aspects and practical solutions of synovial joints treatment for the patients with hip and knee osteoarthritis, realized at Recovery Clinical Hospital of Felix Spa, Oncology Clinical Hospital of Oradea and our university. A theoretical model of human body under applied and conjunction forces, explained the vibration damping...

Background: The benefical effects of the physical training in the second phase of acute myocardial infarction rehabilitation are well-known and were much studied in the speciality literature. The studies carried out in our country are few and done on reduced groups of patients. That's why it is useful to study the evolution of the noninvasive haemo...

The paper has presented the result of tests and researches realized at our university and Oncology Clinical Hospital from Oradea, Radiotherapy Section, about improving of biolubrication between cartilages in relative moving of synovial joints with osteoarthritis, having slow evolution under non-conventional treatment of irradiation with gamma ray....

The main building materials manufactured by S.C. "Congips" S.A. Oradea are the alpha modeling plaster and the expanded polystyrene, obtained through discontinuous manufacturing processes. Researches are conducted in order to obtain a new composition based on alpha modeling plaster with superior sound absorbing and thermal insulating properties. The...

SUMMARRY In this paper we present some aspects regarding the limitation of the action of vibrations upon the human organism. The human organism is an heterogeneous elastic environment, that, under the action of vibrations, amplifies or absorbs them, as stated in the laws of mechanics. In medical therapy, through vibrations, the use of certain frequ...

This study deals with the technology of manufacturing the mold for casting sound absorbing panels. The mold presented at A1 was designed with the assistance of a CAD program, SolidWork 2008 type, after which a CAM program, Solid CAM, was use for the simulation.

Summarry In this work we present the theoretical and practical aspects regarding the use of ultrasound therapy on the human organism (live tissue). This is a biomechanics paper that is centered around the determination of the application limit of ultrasound frequencies upon the human organism over which the heterogeneity of tissue structures could...