Mihaela Badea Doni

Mihaela Badea Doni
National Institute for Research and Development in Chemistry and Petrochemistry | ICECHIM · Department of Biotechnology

PhD

About

98
Publications
24,499
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947
Citations
Additional affiliations
February 2017 - present
December 2015 - present
National Institute for Research and Development in Chemistry and Petrochemistry
Position
  • Senior Scientist I
January 2005 - December 2015
National Institute for Research and Development in Chemistry and Petrochemistry
Position
  • Senior Scientist II

Publications

Publications (98)
Article
Concrete is the most used construction material, but its industrial production from lime consumes 2–3% of the global energy demand, generating 0 [...]
Article
Introduction: For sustainable agriculture, an attempt has been made to reduce the use of fertilizers and agrochemicals, replacing them instead with biostimulants as viable alternatives [...]
Article
Full-text available
The scavenging activity of myoglobin toward peroxynitrite (PON) was studied in meat extracts, using a new developed electrochemical method (based on cobalt phthalocyanine-modified screen-printed carbon electrode, SPCE/CoPc) and calculating kinetic parameters of PON decay (such as half-time and apparent rate constants). As reactive oxygen/nitrogen s...
Article
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Environmental contamination, extensive exploitation of fuel sources and accessibility of natural renewable resources represent the premises for the development of composite biomaterials. These materials have controlled properties, being obtained through processes operated in mild conditions with low costs, and contributing to the valorization of by...
Article
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Cladosporium species are active in protecting plants against different biotic and abiotic stresses. Since these species produced a wide range of secondary metabolites responsible for the adaptation to new habitats, plant health and performance, they are of great interest, especially for biostimulants in agriculture. Cladosporium sp. produces protei...
Article
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This paper presents an overview of the principal structural and dynamics characteristics of reverse micelles (RMs) in order to highlight their structural flexibility and versatility, along with the possibility to modulate their parameters in a controlled manner. The multifunctionality in a large range of different scientific fields is exemplified i...
Article
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Wood, a traditional common material with multiple applications in civil and religious [...]
Article
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Protein hydrolysates, as plant biostimulants, have beneficial effects on the growth, yield and [...]
Article
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The wooden churches made between 1750 and 1850 have as decorative elements paintings madeon wood or wooden panels. [...]
Article
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Sensitive, stable and robust electrochemical sensors have been designed through modificationof the working electrodes with different complex matrices based on carbon nanomaterials andmetallic nanoparticles. Therefore, screen-printed electrodes were modified with complex matrices ofhybrid nanomaterials using physical deposition or entrapment in poly...
Article
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Reactive oxygen/nitrogen species (ROS/RNS) have a great impact on cellular response to stress, cell proliferation, cell death, cancer, aging, or male infertility. Additionally, in the food industry and for consumers as well, it is very important to monitor quality and freshness of raw meat. Different factors are a sign of meat alteration (e.g., dis...
Conference Paper
Full-text available
Reactive oxygen/nitrogen species (ROS/RNS) have great impact on cellular response to stress, cell proliferation, cell death, cancer, aging or male infertility. Also, in the food industry and for consumers, as well, it is very important to monitor quality and freshness of raw meat. Different factors are a sign of meat alteration (e.g. discoloration,...
Article
A spent biomass, which results from the biopharma industry, is stabilized and functionalized by biosorption with microelements. The efficiency of this new biomaterial was tested in two experiments: 1) In a mixture with soil to determine its effects of the germination capacity of cereals and vegetables, and 2) in a formulation of mixed fertilizers t...
Article
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Vernacular buildings are usually constructed using materials at hand, including wood, natural stone and bricks (either clay or mud bricks). All those materials are exposed to a series of environmental factors, affecting their structure and integrity. The literature review was conducted using different databases (Scopus, Web of Science, ScienceDirec...
Article
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Bioanalytical nanosystem based on an innovative hybrid nanomaterials have been developed for sensitive detection of some toxic compounds, such as biogenic amines and xenoestrogens from food and the environment. [...]
Article
Keratinophilic fungi are present in soil as decomposers of keratinous substrates, while keratinolytic fungi have the capacity to decompose native keratin, the insoluble fibrous proteins from living organism. Keratin materials, especially by-products from food industry and animal husbandry must be harnessed through innovative, non-polluting and low-...
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Modern agriculture needs various plant growth stimulant products.
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Determination of aflatoxin M1 in milk and dairy products. [...]
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Protein hydrolysates (PHs) are organic non-microbial biostimulants having beneficial effects on plants. The study was designed to assess the effects on plants by the applications of PHs obtained from Trichoderma isolates grown on keratin wastes. Trichoderma isolates were characterized for indole-3-acetic acid and siderophores production, activity o...
Article
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Polypropylene–cellulose composites have great potential in many important commercial applications, and it is important to understand and properly evaluate their biodegradative behavior to achieve improved composite formulations in accordance with their future applications. In the present study, an outdoor soil burial test was performed in order to...
Preprint
This paper presents an overview of the principal structural and dynamics characteristics of reverse micelles (RMs) in order to highlight their structural flexibility and versatility, along with the possibility to modulate their parameters in a controlled-manner. The multifunctionality in a large range of different scientific fields is exemplified i...
Article
Full-text available
Aflatoxins, which are mainly produced by Aspergillus flavus and parasiticus growing on plants and products stored under inappropriate conditions, represent the most studied group of mycotoxins. Contamination of human and animal milk with aflatoxin M 1 , the hydroxylated metabolite of aflatoxin B 1 , is an important health risk factor due to its car...
Chapter
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The fungi from Trichoderma / Hypocrea genera are among the most studied and most commonly used as active ingredients for the bioproducts used as inputs in agricultural technologies. These bioproducts are presently marketed as bio-pesticides, bio-fertilizers, enhancers of the cultivated plant growth and development or bio-stimulants of the plant def...
Chapter
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Trichoderma strains with plant biostimulant activities represent one of the solution for the drawbacks of high residues farming systems. Beside significant advantages, high residues farming systems present several agronomical disadvantages. High plant residues promote soilborne pathogens by mechanisms as increasing pathogen's shelter for wintering,...
Article
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The aim of this study was to investigate the influence of culture conditions on growth of keratinophilic fungal strain of Chrysosporium sp. in the presence or absence of keratin substrate. The effect of pH, temperature, carbon and nitrogen sources on fungal growth and sporulation was evaluated. The pH values ranged from 4 to 9.5 and the incubation...
Article
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The genus Phytophthora causes great damages to agricultural production, especially to potatoes and tomatoes cultures. To face these losses, it is of interest to reduce or inhibit the activity of this aggressive pathogen. Some species of Trichoderma have great potential for the biological control of several plant pathogens, including diseases caused...
Article
Spent mushroom substrate is considered as one of the ingredients of growing media which could be used partially as peat substitution in the near future. The aim of this research was to enhance the plant biostimulant activity of a spent Pleurotus substrate (SPS) coming from mushroom cultivation on wheat straw, and containing 39.5±1.3% cellulose, 14....
Article
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Background: The hydrolysis of keratin wastes by microorganisms is considered a biotechnological alternative for recycling and valorization through keratinolytic microorganisms. Despite their resistant structure, keratin wastes can be efficiently degraded by various microorganisms through the secretion of keratinases, which are promising enzymes for...
Article
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For the first time the electropolymerization of 2,6-dihydroxynaphthalene (2,6-DHN) on a screen printed carbon electrode (SPCE) was investigated and evaluated for peroxynitrite (PON) detection. Cyclic voltammetry was used to electrodeposit the poly(2,6-DHN) on the carbon electrode surface. The surface morphology and structure of poly(2,6-DHN) film w...
Article
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In the present study, three Trichoderma strains with antagonistic activity towards plant pathogens were tested for their ability to reduce or inhibit the root rot produced by Pythium ultimum under laboratory and greenhouse conditions. Trichoderma asperellum T36 was shown to strongly reduce root rot severity and to improve the anchorage. Maximum inh...
Conference Paper
Full-text available
Keratinophylic fungi are present in the environment with a variable distribution, being influenced by human and animal presence and playing an important role in the biodegradation of keratinized substrates (skin, hair shaft, nails, claws, horns, wool and feathers). These fungi are geophilic, zoophilic and anthropofilic. Keratinophylic fungi have th...
Article
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Microbial plant biostimulants represent one of the solutions for the negative impacts associated with high residues agricultural systems. We developed a hydro-gelified and film forming formulation, which we used for in situ formation of a bio-composite mulch, by treatment on crop residues. Into this hydro-gelified and film forming composition we in...
Patent
Full-text available
The invention refer to a strain of Pseudoxanthomonas mexicana P32 NCAIM (P) B 001414, which present superior characteristics of: degradation of aromatic and aliphatic hydrocarbons in different environments, including soil, including in combination with alfalfa plant roots; produce biofilms in vitro and in situ; stimulates germination of alfalfa see...
Article
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In the present study, several selected formulations based on recycled (rPP) or virgin polyolefins (vPP) and lignocelluloses were prepared and subjected to microorganism attack. Biodegradation tests were performed with microbial strains belonging to fungal genera, like Aspergillus, Penicillium and Fusarium. The initiation of biodegradation was demon...
Patent
Full-text available
The invention refer to a composition including 42.1 parts of fatty acid ethyl esters of linseed oil, 15 parts of lecithin, 13.7 parts of ethyl alcohol, 6 parts essential oil of Syzygium aromaticum flower buds, 6 parts of essential oil of Ageratum houstonianum flower, 5 parts of potassium salts of fatty acids, expressed as oleate, 3.3 parts of glyce...
Article
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The influence of some important experimental variables on the analytical signals of a flow injection analysis (FIA) method with chemiluminescence (CL) detection (FIA-CL) based on the use of the system luminol/Co(Il)/EDTA/H2O2was reported. The principle and application of the method for the determination of total antioxidant capacity (TAC) of differ...
Article
A bioinspired one-pot approach for the synthesis of ZnO - carbohydrate hierarchical architectures was developed. The synergy between a saccharide (mono, di- or polysaccharide) that contains D-glucose units and triethanolamine is the key parameter of the synthetic methodology. The morphology of the ZnO composites is dictated by the used saccharide,...
Article
Full-text available
The aim of this study was to assess the potential of volatile and non-volatile metabolites from antagonistic Trichoderma spp. against phytopathogenic fungi. The biocontrol activity was tested versus the pathogens responsible for important losses in agriculture, such as: Fusarium graminearum, Rhizoctonia solani and Pythium ultimum. In vitro studies...
Patent
Full-text available
nvention relates to a strain of Brevibacillus parabrevis B50, NCAIM (P) B 001413, which present superior characteristics of: in vitro antagonism against phytopathogen agents; biosynthesis of compounds which stimulate the formation of mycorrhiza; endophyte development; innocuity on Galleria mellonella test; protection of maize plants, used as host p...
Article
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The aim of this study was to assess the potential of microbial antagonists to control the growth and mycotoxin production by toxigenic fungal strain Aspergillus niger. Mycotoxins are secondary metabolites that produce acute and chronic effects on human and animal health. Among the mycotoxins of great interest produced by Aspergillus are ochratoxins...
Conference Paper
Full-text available
Biological control represents an important approach of agricultural biotechnology for controlling many fungal plant pathogens. Trichoderma spp. are the most promising and effective bioagents against many plant pathogenic fungi. In present paper, two strains of Trichoderma aspellerum isolated from soil were screened for their efficacy against some c...
Article
Full-text available
The aim of this work was the developing of a sensitive, accurate, reproducible and inexpensive HPLC with fluorescence detection method for the analysis of ochratoxin A in wine samples. Mobile phase composition consisted in methanol/aqueous component (0.1% phosphoric acid) in the ratio 60/40 (v/v). Temperature column was set up to 20°C. The sample c...
Chapter
Instrumentation and operational FIA modes in industrial analysis and the advantages of the application of this technique to industrial process monitoring were discussed. Some relevant examples for the applications of FIA for industrial processes, biotechnological processes, food and beverage industry, and wastewater monitoring were presented.
Article
Differential scanning calorimetry (DSC) technique enabled the study of the effect of the rosemary (Rosmarinus officinalis) extract on polyethylene foils structure and biodegradability. The polyethylene used for food packaging contains synthetic antioxidants which are often able to migrate and to contaminate the food. Natural extracts with antioxida...
Article
Full-text available
Stability of alcohol oxidase from Hansenula polymorpha, during and after the process of entrapment in AOT-isooctane reverse micelles, has been investigated. The study of relationship between pre-micellar components of reverse micelles and catalytic activity/stability of enzyme has revealed a major influence of the apolar solvent upon enzyme stabili...
Article
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A flow injection analysis (FIA) method with fluorimetric detection (FL) for the fast evaluation of the antioxidant actiuity of several synthetic compounds was developed. The method is based on the oxidation of homovanillic acid (HVA), in the presence of hydrogen peroxide H2O2 and horseradish peroxidase (HRP), yielding a fluorescent dimmer compound....
Article
Full-text available
The chemiluminescence (CL) reactions coupled with flow injection techniques can provide good solutions for development of cheap and fast methods for antibiotic determination. In this work, three β-lactam antibiotics, namely: amoxicillin, ampicillin and penicillin G, were determined by using a flow injection analysis (FIA) method based on CL reactio...
Article
Full-text available
New electrochemical sensors for phenol detection have been constructed using inorganic-organic composite materials based on poly(2-[(E)-2-azulene-1-yl)vinyl] thiophene) (PAVT) and Prussian Blue (PB). The PAVT films were generated by electrochemical polymerisation within two different potential ranges, i.e. from -0.6 to 1.2 V and from -0.6 to 1.8 V,...
Article
Full-text available
New electrochemical sensors for phenol detection have been constructed using inorganic-organic composite materials based on poly(2-[(E)-2-azulene-1-yl)vinyl] thiophene) (PAVT) and Prussian Blue (PB). The PAVT films were generated by electrochemical polymerisation within two different potential ranges, i.e. from-0.6 to 1.2 V and from-0.6 to 1.8 V, r...
Article
Full-text available
Mycotoxins are secondary metabolites produced by several filamentous fungi that grow on various food and feed. These compounds elicit a wide spectrum of toxicological effects, representing a health risk for both, humans and animals. Mycotoxin analysis is an important tool in controlling fungal contamination of food and feed. This article reviews th...
Article
Full-text available
New electrochemical sensors for phenol detection have been constructed using inorganic-organic composite materials based on poly(2-[(E)-2-azulene-1-yl)vinyl] thiophene) (PAVT) and Prussian Blue (PB). The PAVT films were generated by electrochemical polymerisation within two different potential ranges, i.e. from-0.6 to 1.2 V and from-0.6 to 1.8 V, r...
Article
Full-text available
The production and assembling of disposable electrochemical AFM1 immunosensors, which can combine the high selectivity of immunoanalysis with the ease of the electrochemical probes, has been carried out. Firstly immunoassay parameters such as amounts of antibody and labelled antigen, buffer and pH, length of time and temperature of each steps (prec...
Article
A flow-injection immunoassay (FI-IA) method with amperometric detection for aflatoxin M1 (AFM1) determination in milk has been developed. The first step consists in an incubation of the sample containing AFM1 (Ag) with fixed amounts of anti-AFM1 antibody (Ab) and of the tracer (Ag∗, AFM1 covalently coupled to HRP) until equilibrium is reached. In t...