Miguel A Teus

Miguel A Teus
University of Alcalá | UAH · Department of Surgery, Medical and Social Sciences

MD, PhD. Professor in Ophthalmology

About

351
Publications
28,437
Reads
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3,084
Citations
Introduction
Miguel A Teus currently works at the Department of Surgery, Medical and Social Sciences, University of Alcalá School of Medicine, Alcalá de Henares, Madrid, Spain, and in Novovision clinic, Madrid, Spain. Miguel does research in Ophthalmology. He is interested in femtolaser technology for corneal laser vision correction, IOLs and in glaucoma (diagnosis and treatment). https://miguelteus.es
Additional affiliations
December 2011 - present
University of Alcalá
Position
  • Chairman of ophthalmology
May 2002 - December 2011
University of Alcalá
Position
  • Full profesor of ophthalmology
April 1996 - May 2002
University of Alcalá
Position
  • Professor (Associate)
Education
September 1992 - June 1993
University of Alcalá
Field of study
  • Glaucoma
May 1984 - January 1988
Hospital Universitario Ramón y Cajal
Field of study
  • Residence in ophthalmology
September 1976 - June 1982
Universidad de Valladolid
Field of study
  • Medicine

Publications

Publications (351)
Article
Purpose: To analyze changes in tear osmolarity and the Ocular Surface Disease Index (OSDI) in patients after cataract surgery. Design: Prospective, observational cohort study. Methods: Setting: Institutional. Patient population: Fifty-two patients with a unilateral cataract (study eye) scheduled for surgery and good visual function in the fe...
Article
To compare anterior and posterior corneal curvatures between eyes with primary open-angle glaucoma (POAG) and healthy eyes. This is a prospective, cross-sectional, observer-masked study. A total of 138 white subjects (one eye per patient) were consecutively recruited; 69 eyes had POAG (study group), and the other 69 comprised a group of healthy con...
Article
To evaluate "in vivo" the effect of topical travoprost on the central corneal thickness (CCT) of rabbit eyes, and the changes in the CCT after acute increases of intraocular pressure (IOP) in these eyes. This is an interventional, prospective, case-control, masked study. Topical travoprost was applied once daily for one month to the right eye of si...
Article
Prostaglandin F(2alpha) analogues, such as latanoprost, may cause a decrease in the extracellular matrices, such as collagen, and changes in fibrillin-1; both are components of the ciliary zonules. However, the mechanical effect of these changes on the dynamics of the ciliary zonules is unknown. This study was conducted to evaluate the effect of la...
Article
To study the effect of patient age on the incidence of latanoprost-induced increases in iris pigmentation. Prospective observational observer-masked study. Thirty-six patients younger than 60 years (group 1) and 36 patients older than 75 years (group 2) with primary open-angle glaucoma. We photographed both irises of each patient before and 6 month...
Article
Full-text available
Introduction: To compare the influence of one microkeratome and three femtosecond lasers on myopic laser in situ keratomileusis (LASIK) outcomes. Methods: Retrospective, observational cohort study. We compared 134 eyes treated with the IntraLase 60 kHz, 112 eyes treated with the Femto LDV Z6, 206 eyes treated with the FS200, and 98 eyes treated...
Article
Background and objective The SARS-CoV-2 pandemic has caused chaos in all health systems on the planet. It has been difficult to cope with COVID 19, but also to maintain the activity in other specialties. In ophthalmology, the scientific societies recommended providing urgent care, including the intravitreal treatment of patients with active neovasc...
Article
Full-text available
Neuro Lyme disease is caused by several bacteriae of the Borreliaceae family, such as Borrelia Miyamotoi. In late stages of illness, patients with Lyme disease may develop chronic neurologic symptoms such as cognitive disturbances or small fiber peripheral neuropathy. Confocal microscopy is a non-invasive method designed to evaluate the human corne...
Article
Purpose The purpose of this study was to measure the luminal diameter of the PreserFlo® microshunt and to calculate the theoretical resistance to flow for comparison with the outcomes of the in vitro flow testing of this device. Methods The PreserFlo® was designed to control the flow of aqueous humor by means of its length and width according to t...
Article
Full-text available
Introduction Higher preoperative myopic astigmatism is associated with a higher probability of retreatment due to patient dissatisfaction as a result of residual cylindrical error. Nonetheless, retreatment is safe and the final clinical results are comparable to those of patients with lower preoperative astigmatism who were satisfied with the prima...
Article
Full-text available
Background and objective: The SARS-CoV-2 pandemic has caused chaos in all health systems on the planet. It has been difficult to cope with COVID 19, but also to maintain the activity in other specialties. In ophthalmology, the scientific societies recommended providing urgent care, including the intravitreal treatment of patients with active neova...
Article
Full-text available
IntroductionTo analyze the effects of PRESERFLO on corneal endothelial cell density (ECD).Methods Forty-six eyes that underwent PRESERFLO implantation were followed up for 12 months. Specular microscopy was performed preoperatively and at 1, 3, 6, and 12 months postoperatively to measure central ECD and mean monthly reduction (MMR). Anterior segmen...
Article
Full-text available
Purpose: To measure the in vitro flow properties of the PRESERFLO implant for comparison with the theoretical resistance to flow. Methods: The PRESERFLO was designed to control the flow of aqueous humor according to the Hagen-Poiseuille (HP) equation. Scanning electron microscopy (SEM) was performed to analyze the ultrastructure, and flow measur...
Preprint
Full-text available
Introduction: It is well known that the femtosecond laser lamellar cut has some degree of roughness. Nevertheless, as in femtosecond laser assisted LASIK (FS-LASIK), an excimer LASIK ablation is performed, the post-ablation stromal bed should show a marked decrease in roughness. We decided to compare, using atomic force microscopy (AFM), the roughn...
Article
Aniridia is a congenital bilateral ocular disorder with dominant autosomal inheritance. More than 50% of patients will develop aniridic glaucoma (AG) during their lives. Open angle glaucoma is more common in aniridia, but a closed angle mechanism has been described in relation with anterior rotation of the rudimentary iris, occluding trabecular mes...
Article
Full-text available
The most common cause of vision impairment in children is amblyopia. It is defined as impaired visual acuity in one or both eyes that is present with no demonstrable abnormality of the visual pathway and is not immediately resolved by wearing glasses. After the World Health Organization (WHO) recognized COVID-19 as a global pandemic on March 11, 20...
Article
Purpose To analyse the effect of femtosecond laser-assisted in situ keratomileusis (FS-LASIK) on the electrical response of retinal ganglion cells using pattern electroretinography (pERG). Methods This was a longitudinal, prospective, observational pilot study. We included consecutive myopic patients who underwent FS-LASIK to correct up to 6 diopt...
Article
Full-text available
This is a retrospective, multicenter study of consecutive patients with nAMD scheduled for a visit and/or a treatment with an intravitreal injection (IVI) during the 3 months before lockdown in the Ophthalmology Departments of six centers of Europe.The study was conducted on 546 patients, of which 55.13% were females, almost 100% of the patients we...
Article
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Introduction: The aim of this study was to evaluate the correlation between several ocular parameters (intraocular pressure [IOP], corneal biomechanical properties) and the visual field (VF) mean deviation (VF MD) in eyes with open-angle glaucoma (OAG). Methods: We conducted a cross-sectional, observational study in which we measured the IOP wit...
Article
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Background To compare the anterior surface roughness of two commercially available posterior chamber phakic intraocular lenses (IOLs) using atomic force microscopy (AFM). Methods Four phakic IOLs were used for this prospective, experimental study: two Visian ICL EVO+ V5 lenses and two iPCL 2.0 lenses. All of them were brand new, were not previousl...
Article
Precise: Glaucoma surgery with the PRESERFLO Microshunt shows mild and transient changes in the corneal astigmatism, the corneal elevation and biometrics in the early postoperative period. The posterior corneal elevation tends to be higher in POAG. Purpose: To determine the changes in the corneal keratometry, astigmatism and elevation, refractio...
Article
Objective To estimate the cost-effectiveness of two trabecular micro-bypass stent implants (iStent inject®) during cataract surgery, compared to cataract surgery alone, in patients with cataracts and mild-to-moderate primary Open Angle Glaucoma (OAG) in the Spanish National Health System (SNHS). Methods A Markov model was used to simulate the prog...
Article
Full-text available
Purpose To compare the induced corneal stromal bed roughness measured with atomic force microscopy (AFM) after LASIK flap creation with the IntraLase 60 kHz and the VisuMax femtosecond laser platforms. Methods Three freshly enucleated porcine eyes were operated with each femtosecond laser in this experimental study. Standard LASIK treatment parame...
Article
Full-text available
Purpose To assess the 3‐year effectiveness and safety of the XEN gel stent implanted ab interno in open‐angle glaucoma (OAG). Methods This study was a multicentre, retrospective chart review of consecutive patients with OAG who underwent ab‐interno gel stent placement alone or combined with phacoemulsification between 1 January 2014 and 1 October...
Article
Our purpose is to report the intermediate-term results of the Ex-PRESS® implant as the first surgical option in patients with Iridocorneal Endothelial (ICE) Syndrome. We describe two patients diagnosed from ICE syndrome with medically uncontrolled glaucoma and finally treated with an Ex-PRESS® implant, associating a cataract surgery in one of them....
Article
Full-text available
Since the World Health Organization declared COVID-19 to be a pandemic on 11th March 2020, changes to social and sanitary practices have included significant issues in access and management of eye care during the COVID-19 pandemic. Additionally, the fear of loss, coupled with social distancing, lockdown, economic instability, and uncertainty, hav...
Article
Purpose: To analyse the morphological evolution of filtering blebs with anterior-segment OCT (AS-OCT) and its correlation with intraocular pressure after ab externo SIBS microshunt implantation with mitomycin C (MMC) during a 3-month follow-up period. Methods: Twenty-eight filtering blebs of 28 patients with open-angle glaucoma were measured hor...
Article
Significance: The development of confocal microscopy allows one to obtain high-resolution corneal images like its optical density. Some studies have evaluated the optical density with Scheimpflug cameras in the early post-operative period after photorefractive keratectomy, but no studies have evaluated the long-term evolution of optical density af...
Article
Full-text available
Purpose: The purpose of this study was to measure the intraocular pressure (IOP) elevation during laser assisted in situ keratomileusis (LASIK) flap creation using the WaveLight FS200 femtosecond (FS) laser platform. Methods: We conducted an ex vivo experimental study in an animal model. The WaveLight FS200 FS laser platform was used to perform...
Article
Resumen Se plantea como objetivo dar a conocer los resultados a mediano plazo del implante Ex-PRESS® como primera opción quirúrgica en pacientes con síndrome iridocorneo-endotelial (ICE). Se incluye la descripción de dos mujeres con diagnóstico de síndrome ICE y glaucoma no controlado por medicación, tratadas con el implante Ex-PRESS® y con cirugía...
Article
Resumen La aniridia es un trastorno ocular bilateral congénito de herencia habitualmente autosómica dominante, más infrecuentemente recesiva asociada al síndrome de Gillespie. Más de un 50% de pacientes con este trastorno van a presentar glaucoma anirídico (GA) a lo largo de su vida. En la mayoría de los casos es de ángulo abierto, pero también pue...
Article
Full-text available
The progressive deterioration of the visual function in patients on waiting lists for cataract surgery has a negative impact on their quality of life, especially in the elderly population. Patient waiting times for cataract surgeries in many healthcare settings have increased recently due to the prolonged stop or slowdown of elective cataract surge...
Article
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PurposeThinner central corneal thickness (CCT) is a risk factor for conversion from ocular hypertension to glaucoma and for disease progression. However, little is known about the relationship between CCT and characteristics of the optic nerve and the retinal nerve fibre layer (RNFL) in non-glaucomatous eyes. Because myopic eyes may pose diagnostic...
Article
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Uveal melanoma is the most common type of intraocular cancer with a low mean annual incidence of 5-10 cases per million. Tumours are located in the choroid (90%), ciliary body (6%) or iris (4%) and of 85% are primary tumours. As in cutaneous melanoma, tumours arise in melanocytes; however, the characteristics of uveal melanoma differ, accounting fo...
Article
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The key clinical attributes of preserved dorzolamide/timolol fixed combination (DTFC) and the emerging potential of preservative-free (PF) DTFC are reviewed with published evidence and clinical experience. The indications and role of DTFC in current glaucoma management are critically discussed. Preserved DTFC became the first intraocular pressure (...
Article
Purpose: To compare the thickness and stromal optical density (OD) evolution of the flap and cap after femtosecond (FS-LASIK; Visumax) and small incision lenticule extraction (SMILE), respectively, for myopia correction. Methods: A prospective study comprising 78 eyes (n=39 per group) was performed. Anterior segment optical coherence tomography...
Article
Full-text available
The recent outbreak of coronavirus disease 2019 (COVID-19) has been declared a public health emergency worldwide. The scientific community has put in much effort and published studies that described COVID-19's biology, transmission, clinical diagnosis, candidate therapeutics, and vaccines. However, to date, only a few data are available on the impa...
Article
Introduction Fixed dose combinations (FCs) represent a potentially valuable treatment strategy in glaucoma management. Fixed combinations not only improve adherence by reducing the medication burden, but also decrease the total amount of potentially deleterious preservatives an eye is exposed to. Areas covered We provide a critical review of selec...
Article
Our purpose is to document the first case of unilateral mild corneal ectasia developed in an apparently non-predisposed cornea after topical latanoprost treatment, and its regression after treatment withdrawal. We describe a 44-year-old man with visual impairment in his left eye (OS) and a past medical history of myopic refraction and ocular hypert...
Article
Purpose: To assess the relevance of the homogeneity of femtosecond laser (FSL) flap thickness regarding induction of higher order aberrations (HOAs). Setting: Clínica Rementería & Clínica Novovisión, Madrid, Spain. Design: Prospective, observational study. Methods: Two hundred thirty-one patients who underwent in situ keratomileusis using fi...
Article
Purpose: To describe the postoperative evolution of visual acuity, flap morphology, and stromal optical density femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK). Setting: Clínica Rementería, Madrid, Spain. Design: Prospective case series. Methods: The study comprised 44 consecutive eyes that had FS-LASIK performed with the...
Article
Full-text available
Purpose To describe and compare the stromal bed roughness obtained after laser in situ keratomileusis (LASIK) flap creation using a corneal femtosecond laser platform (iFS 150) and a “dual” femtosecond (FS) laser platform (LenSx). Methods This ex vivo experimental study was conducted in an animal model using 12 freshly enucleated porcine eyes, six...
Article
Purpose Anti‐inflammatory treatment of moderate‐to‐severe dry eye disease (DED) remains a challenge with a need for eye drops showing better efficacy and tolerability. The effect of MC2‐03, a novel ciclosporin (CsA) eye drop using PAD™ Technology, was investigated in humans. Methods The NORTHERN LIGHTS trial is a 6 month phase 2b, multicenter, ran...
Article
Full-text available
Background: To compare the visual and refractive outcomes after myopic LASEK using three different excimer lasers and standardized surgical and mitomycin C (MMC) application protocols. Methods: In this retrospective, observational cohort study, we examined 122 eyes treated with Allegretto, 135 eyes treated with Esiris and 137 eyes treated with T...
Article
Purpose: To perform in vitro assessments of surface haze and roughness, subsurface nanoglistenings (SSNGs), and glistenings of a new hydrophobic acrylic intraocular lens (IOL) in comparison to commercially available IOLs. Setting: Universities of Utah and Alcalá, and Alcon Vision, LLC. Design: Experimental study. Methods: The IOLs used were...
Article
Purpose To evaluate the apparent intraocular pressure (IOP) change observed after treatment with latanoprost in naive eyes of patients with primary open‐angle glaucoma (POAG) or ocular hypertension (OHT) using Goldmann applanation tonometer (GAT), ocular response analyzer (ORA) and Corvis ST tonometry. Methods Prospective observational cohort stud...
Conference Paper
Full-text available
Background Sjögren’s syndrome is one of the most common rheumatic autoimmune disorders (1). It is a chronic systemic autoimmune disease in which immunomediated inflammation, characterized by lymphocytic infiltration of exocrine glands and epithelia, causes secretory gland dysfunction leading to dryness of the main mucosal surfaces (2) including dry...
Article
Purpose: To measure intraocular pressure (IOP) elevations in porcine eyes during laser in situ keratomileusis (LASIK) performed using 3 femtosecond laser platforms. Setting: Clínica Novovisión, Madrid, Spain. Design: Experimental study. Methods: Three femtosecond devices, the iFS 150 kHz, which is the newest-generation IntraLase with a flat...
Article
Full-text available
Purpose The purpose of this study was to use Triton® SweptSource OCT to evaluate the morphology of blebs formed when eyes are treated with XEN® implants and to compare these with the blebs in successfully functioning eyes after trabeculectomy (TB) and with eyes of healthy controls. Methods A cross-sectional, observational study. We analyzed 25 eye...
Preprint
Full-text available
BACKGROUND To compare the influence of four different microkeratomes on myopic LASIK outcomes. METHODS Retrospective, observational cohort study. We compared 134 eyes treated with the IntraLase 60 kHz, 112 eyes treated with the Femto LDV Z6, 206 eyes treated with the FS200 and 98 eyes treated with the Hansatome zero compression microkeratome. All e...
Article
Purpose: To analyze the recovery of the subbasal nerve plexus in corneas treated with laser in situ keratomileusis (LASIK) at least 10 years prior compared with nonoperated corneas. Setting: Clínica Novovisión, Madrid, Spain. Design: Prospective nonrandomized observational study. Methods: Eyes that had LASIK surgery at least 10 years before...
Article
Full-text available
AIM: To evaluate the effect of age on visual and refractive results after laser in situ keratomileusis (LASIK) obtained with a mechanical microkeratome or a femtosecond laser. METHODS: Retrospective, nonrandomized, cohort study. A total of 3826 eyes were included in the study (1725 eyes treated with mechanical LASIK and 2101 eyes treated with femto...
Article
Full-text available
During the last 2 decades, modifying the shape of the cornea by means of laser photoablation has emerged as a successful and popular treatment option for refractive errors. Corneal surface ablation techniques such as photorefractive keratectomy (PRK) and laser-assisted subepithelial keratomileusis (LASEK) offer good refractive results while having...
Article
Purpose To evaluate the influence of age on visual and refractive results after laser-assisted subepithelial keratomileusis (LASEK) with the adjuvant use of mitomycin C (MMC) for the correction of myopia. Methods Retrospective, nonrandomized, cohort study. A total of 1374 eyes treated with LASEK + MMC were included in the study (we compared 1163 e...
Article
Full-text available
Objective To evaluate in an in vivo rabbit model, the effect of topical timolol maleate therapy on the central corneal thickness response to acute intraocular pressure increases. Method In this prospective and interventional controlled study, the central corneal thickness and intraocular pressure were measured in vivo in 12 rabbit eyes treated wit...
Article
Objective: To determine the economic impact of the XEN® Gel Stent implant inclusion into the therapeutic arsenal for surgical treatment of open-angle glaucoma in Spain. Methods: A budget-impact analysis was designed to estimate the costs of surgical intervention in patients with not-controlled glaucoma from the perspective of the Spanish National H...
Article
The first surgical modalities to reduce aqueous humor production by damaging the ciliary body date back to the early twentieth century. Until recently, however, cyclodestructive procedures (e.g., cyclocryotherapy and transscleral diode laser photocoagulation) have been reserved as last option procedures in refractory glaucoma patients with poor vis...
Article
Full-text available
Purpose To compare the hypotensive effect of travoprost 0.004%/timolol 0.5% fixed combination (TTFC) to the concomitant use of travoprost and timolol 0.1% gel formulation (Trav + Geltim). Materials and methods Thirty-three patients (62 eyes) were enrolled and divided into two groups. Patients in group 1 (31 eyes) received the TTFC and patients in...