
Miguel Enrique Sanchez-HechavarriaUniversidad Católica de la Santísima Concepción | UCSC · Departamento de Ciencias Clínicas y Preclínicas
Miguel Enrique Sanchez-Hechavarria
MD. Specialist
About
77
Publications
12,698
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49
Citations
Citations since 2017
Introduction
I am working with a vision from the physiology, physiopathology, bioingineering and medical anthropology aspects related to chronic diseases (cardiovascular diseases and cancer), Relaxation techniques, Stress and Exercise, Cardiovascular Health and Modeling of Developmental Neurobiology.
I am also dedicated now to the topic of "Physiological Synchrony"
Additional affiliations
July 2021 - present
Universidad Advestista de Chile
Position
- Researcher
April 2019 - present
April 2019 - present
Education
February 2020 - January 2024
August 2013 - October 2017
Medical Sciences University of Santiago de Cuba
Field of study
- Physiology
September 2007 - July 2013
Medical Sciences University of Santiago de Cuba
Field of study
- Medicina
Publications
Publications (77)
Background: The Gini coefficient is a statistical tool generally used by economists to quantify income inequality.
However, it can be applied to any kind of data with unequal distribution, including heart rate variability (HRV).
Objectives: To assess the application of the Gini coefficient to measure inequality in power spectral density of RR
inter...
ABSTRACT
Purpose: To assess the relationship between emotional eating behavior and heart rate variability in Spanish adolescents during an isometric exercise test.
Methods: Participants included 52 adolescents aged between 13 and 18 years old. Heart rate was continuously recorded at rest (2 minutes) and during the sustained weight test
(2 minutes)....
The embryonic developing cerebral cortex is characterized by the presence of distinctive cell types such as progenitor pools, immature projection neurons and interneurons. Each of these cell types is diverse on itself, but they all take part of the developmental process responding to intrinsic and extrinsic cues that can affect their calcium oscill...
Theil entropy is a statistical measure used in economics to quantify the income inequalities. However, it can be applied to any data distribution such as biological signals. In this work, we used different spectral methods in Heart Rate Variability signals and in calcium oscillations, where the use of Theil entropy was explored. The behavior of The...
This study evaluates the emotionality associated with vaccination
against COVID-19 using the sentiment analysis technique of tweets in Spanish-speaking Ibero-American countries.
Method: In January 2021 a mixed cross-sectional observational study
of 41 023 tweets from nine Spanish-speaking Ibero-American countries (Chile, El Salvador, Venezuela, Ec...
El modelo de estrés biológico refiere que el tipo de respuesta adaptativa a los estresores van a depender de la fase del proceso. Algunas de estas respuestas indican disminución de la adaptabilidad y menor caos en las oscilaciones del ritmo cardiaco. En la presente revisión teórica se exponen los hallazgos experimentales que utilizan la entropía mu...
Emotional eating is a maladaptive generalized behaviour to regulate emotions as a momentary solution, and it is characterized by excessive food intake during states of emotional excitement or stress. The heart rate variability (HRV) as an evaluative parameter of emotional regulation indicates that the decrease of the vagal tone in the HRV is positi...
Introduction: Gini coefficient (Gini index or Gini ratio) is a parameter that is normally used in economy to measure the income distribution in a country or in the whole wide world, but it can be used to measure any kind of distribution. In the present study it is exposed an innovative proposal of application of the Gini coefficient to Heart Rate V...
Background:
Predicting beat-to-beat blood pressure has several clinical applications. While most machine learning models focus on accuracy, it is necessary to build models that explain the relationships of hemodynamical parameters with blood pressure without sacrificing accuracy, especially during exercise.
Objective:
The aim of this study is to...
Objective: To determine the response of non-linear parameters of autonomic balance to induced cardiovascular hyperresponsiveness in hypertensive patients.
Method: A cross-sectional analytical observational study was carried out with a non-equivalent control group, carried out in the Laboratory of Basic Biomedical Sciences of the University of Medic...
Bioimpedance is largely used in dialysis patients instead, being a simple, precise, noninvasive and inexpensive method to assess fluid status and body composition. This scoping review aims to describe and synthesize scientific evidence on bioimpedance technologies use in dialysis patients. A literature search was done for peer-reviewed journal clin...
Changes in sympathetic nervous system (SNS) and parasympathetic nervous system (PNS) influences on cardiac rhythm during exercise can be reflected in time- and frequency-based heart rate variability (HRV) analysis and differ depending on exercise intensity. However, the SNS and PNS contributions to cardiac rhythm at the onset of exercise has not be...
Introduction: the metabolic syndrome has a high incidence, causing functional and humoral alterations.
Objectives: to determine clinical-humoral characteristics and endothelial alterations associated with the metabolic syndrome.
Method: cross-sectional analytical observational study in patients with a diagnosis of metabolic syndrome admitted to the...
Introducción:
En este estudio se evalúa la emocionalidad asociada a la vacunación contra el COVID-19 a partir de la técnica de análisis de sentimientos de los tweets en países iberoamericanos hispanohablantes.
Método:
En enero de 2021 se realizó un estudio mixto observacional transversal de 41023 tweets procedentes de nueve países iberoamericanos...
Background:
In primary monosymptomatic enuresis, it is not clear what dynamic changes occur in the efficacy of hypnotherapeutic versus pharmacological treatment plan.
Objective:
Determine the changes over time in the effectiveness of hypnotherapy and a pharmacological treatment plan in primary monosymptomatic enuresis.
Method:
A prospective, long...
Introduction: The analysis of non-linear dynamics of cardiovascular autonomic regulation based on heart rate variability has
not been previously studied in patients with type 2 diabetes mellitus using the sustained weight test as an inducer of cardiovascular hyperreactivity. Objective: To determine the variations in the non-linear dynamics of cardi...
Introduction: Peripheral artery disease (PAD) may present with no symptoms at all, hence the need for diagnosis to avoid complications.
Objective: To determine the presence of peripheral artery disease by means of the ankle-brachial index obtained by photoplethysmography in prehypertensive patients.
Method: A descriptive cross-sectional study was c...
Purpose: The aim of the present study was to investigate the role occlusion time in dynamic changes of autonomic activation during reactive hyperemia
Methods: Healthy subjects (n = 30) in the age range of 18–25 years participated in this study. Vascular reactivity was assessed by measuring the dynamic changes in finger pulse volume amplitude (PVA)...
Introduction: Sustained Weight Test (SWT), is an isometric stress test that has great practical value to perform massive investigations of hypertension
Objective: To determine the variations in the dynamics of cardiac autonomic regulation and in the hemodynamic response during SWT in hypertensive subjects.
Methodological Design: A quasi-experimenta...
Purpose: To determine the influence of emotional alterations in the arterial stiffness index and cardiovascular risk of pre-hypertensive patients.
Methods: A cross-sectional study was carried out in 48 pre-hypertensive patients. Emotional alterations, global cardiovascular risk and arterial stiffness index were evaluated. The PPG technique was used...
Introduction: Cardiovascular autonomic modulation can be considered a useful tool in determining the physiological state of the interaction between the autonomic nervous system and the cardiovascular system.
Objectives: To determine the differences in linear parameters of the basal autonomic balance between medical students and young baseball playe...
Second edition of the Iván Pávlov research grant: an opportunity for Cuban science in applied psychophysiology and neurophysiology
Introduction: Acute mental stress and states of anxiety induced to influence psychophysiological reactivity in healthy young people, result in changes in nervous patterns which may be measured in terms of heart rate variability.
Objective: Determine the differences in linear parameters for autonomic cardiovascular balance in young individuals at ba...
Ivan Pavlov summer scholarship: an space for science development
Introduction: At present it is indispensable to study type 2 diabetes mellitus with lowcost techniques due to the health load it represents. In this context the sustained weight test acquires great value as a Cuban static isometric exercise for the study of heart rate
variability.
Objective: Determine autonomic and hemodynamic electrophysiological...
This database of RR intervals in healthy subjects at rest and mental stress was used in the article "Introduction of Application of Gini Coefficient to Heart Rate Variability Spectrum for Mental Stress Evaluation" (https://www.researchgate.net/publication/335283138_Introduction_of_Application_of_Gini_Coefficient_to_Heart_Rate_Variability_Spectrum_f...
It is known that social inequality is already at its root a moral problem that must be corrected through a new social pact, a new vision of society in which the other is treated as an "other self", revoking the loss of the image of neighbor, who has been beaten by an economist, short-term, reductionist construct that sees the person as another agen...
Introduction: In recent years, the relationship between the systematic practice of physical exercise, cardiovascular dynamics and the functioning of the autonomic nervous system has been recognized. Objective: To determine the modifications that non-linear parameters undergo in the autonomic cardiovascular regulation of the heart rate variability w...
Introduction: In recent years, the relationship between the systematic practice of
physical exercise, cardiovascular dynamics and the functioning of the autonomic nervous
system has been recognized.
Objective: To determine the modifications that non-linear parameters undergo in the
autonomic cardiovascular regulation of the heart rate variability w...
Introduction: In recent years, the relationship between the systematic practice of
physical exercise, cardiovascular dynamics and the functioning of the autonomic nervous
system has been recognized.
Objective: To determine the modifications that non-linear parameters undergo in the
autonomic cardiovascular regulation of the heart rate variability w...
Introducción: las enfermedades cardiovasculares constituyen una de las causas más importantes de morbilidad, discapacidad y muerte prematura a nivel mundial. El control de los factores de riesgo es un elemento imprescindible para su prevención en la atención primaria, por lo cual es importante la estimación del riesgo.
Objetivo: determinar el valor...
Undergraduate scientific research occupies an important place in the training of professionals of Medical Sciences in Cuba, which has generated new learning forms. Considering this, some authors have referred to the initiative of the Henrich Quincke Research Grant, developed by the Central Laboratory of Cerebrospinal Fluid of the Universidad de Cie...
Introduction: The dynamic weight-bearing test (WBT) is a Cuban isometric exercise, similar to the hand grip test, which is very useful to induce hemodynamic modifications to identify cardiovascular hyperreactivity in at-risk populations. However, changes in the cardiovascular autonomic response during weightbearing test are poorly understood .
Obj...
Background and Objectives: The Gini coefficient is a statistical tool generally used by economists to quantify income inequality. To assess the application of the Gini Coefficient to measure inequality in power spectral density of RR intervals, and to use this application as a psychophysiological indicator of mental stress.
Methods: Thirteen health...
Introduction: The autonomic nervous system has been related to an increase in heart rate, blood pressure and cardiac output in situations of stress.
Objective: To determine the modifications that the non-linear parameters undergo in the autonomic cardiovascular regulation of the heart rate variability subjected to mental stress through the mental a...
Introduction: The autonomic nervous system has been related to an increase in heart rate, blood pressure and cardiac output in situations of stress.
Objective: To determine the modifications that the non-linear parameters undergo in the autonomic cardiovascular regulation of the heart rate variability subjected to mental stress through the mental a...
"Criticalidad autoorganizada y moderación Aristotélica como principios generales isomórficos en sistemas de diferente naturaleza " .El concepto de isomorfismo proviene del latin iso: igual y morfo: forma. Las estructuras isomórficas son aquellas organizaciones de diferente naturaleza que guardan semejanzas y correspondencias formales entre sus comp...
RESUMEN Introducción: Annona squamosa L., perteneciente a la familia de las Annonaceae, se conoce también con el nombre de anón. El principal interés económico de esta familia son sus frutos comestibles. Muchas especies de las anonáceas tienen usos locales en la farmacopea gracias a sus componentes químicos. Objetivos: Caracterizar mediante tamizaj...
Introduction: In recent years, the relationship between the systematic practice of
physical exercise, cardiovascular dynamics and the functioning of the autonomic
nervous system has been recognized.
Objective: To determine the modifications that non-linear parameters undergo in the
autonomic cardiovascular regulation of the heart rate variability w...
Immediately following cessation of exercise, central command and muscle mechanoreflex inputs are removed but muscle metaboreflex input can remain in certain situations. Continuous wavelet transform (CWT) analysis is an approach that allows analysis of heart rate variability (HRV) at times of rapid autonomic nervous system adjustments. Recent prelim...
Introducción:
La prueba del peso sostenido (PPS) es un ejercicio isométrico cubano, similar a la de handgrip, de mucha utilidad para inducir modificaciones hemodinámicas que permiten identificar la hiperreactividad cardiovascular en poblaciones de riesgo. Sin embargo, los cambios en la respuesta autonómica cardiovascular durante la PPS no se encuen...
The present article is directed to systematize a theoretical and methodological conception that sustains the process of university extension in the career of Cuban medicine. Among the results he/she stands out the place and paper of the university extension in the system of the integral formation from the professional to which a special connotation...
In the cardiovascular autonomic response under hypnotic state has described
that existing a deviation in the interaction of the sympatheticvagal
balance toward a parasympathetic modulation, however in this state
not has elucidated the nonlinear changes in the regulatory systems of the
heart rate from complexity and chaos theory. Purpose: Determinin...
The environmental and psychosocial factors have an important role in the
development of cardiovascular diseases, constituting the distress one of
the triggers of hypertension and an element present in early stages of it.
Objective: To determine the influence of emotional alterations in the index
of arterial stiffness and cardiovascular risk of preh...
Tesis para optar por el título de especialista en primer grado de fisiología normal y patológica.
La hiperemia reactiva es una respuesta complicada a la isquemia, y refleja los cambios dinámicos en el flujo y en la dilatación de la microvasculatura, que dependen de la actividad del endotelio y del sistema nervioso autónomo. El objetivo de esta inve...
Introducción: La Prueba del Peso Sostenido es un ejercicio isométrico cubano, similar al test de Hand grip, de mucha utilidad para inducir modificaciones hemodinámicas que permiten identificar la hiperreactividad cardiovascular en poblaciones de riesgo. Sin embargo los cambios en la respuesta autonómica cardiovascular durante la PPS no se encuentra...
Introduction: Digoxin is one of the most used drugs in cardiovascular diseases,frequent in the geriatric patient, characterized by its narrow therapeutic margin.
Objectives: To characterize the prescription of digoxin and identify problems related to its prescription in geriatric patients.
Method: A descriptive and cross-sectional study was carried...
Introduction: The application of methods for the detection of clinical points of interest of the pulse wave allows obtaining parameters such as the index of vascular rigidity and reflection that facilitate the evaluation of the vascular effects of aging, hypertension and atherosclerosis. For this reason, the appropriate localization of the onset, s...
Immediately following cessation of exercise, central command and muscle mechanoreflex inputs are removed but muscle metaboreflex input can remain in certain situations. Continuous wavelet transform allows analysis of heart rate variability (HRV) at times of rapid autonomic adjustments. However, it is unknown whether CWT can identify the rapid auton...
Introducción: La necesidad de implementar nuevas variables como el estado nutricional en la evaluación integral del paciente con cáncer de pulmón para mejor resultado de los tratamientos es indispensable. En nuestro contexto existe insuficiente evidencia del valor de los indicadores del estado nutricional de estos pacientes.
Objetivo: Caracterizar...
Tesis para optar por el título de especialista en primer grado de fisiología normal y patológica.
Objetivo: Determinar las variaciones en la dinámica de la regulación autonómica cardiaca y en la respuesta hemodinámica durante Prueba del Peso Sostenido en sujetos normotensos e hipertensos.
Diseño Metodológico: Se realizó un estudio cuasi-experiment...
Introduction: The assessment of the vascular state is one of the pillars in the prevention of cardiovascular diseases in elite athletes, as well as in the general population. The reflection indexes and the arterial stiffness of the pulse wave are objective elements that favor this assessment.
Objective: To characterize the high-performance baseball...
Approximately 30 indices have been proposed for assessing heart rate variability (HRV). Some are mathematically identical or very closely related to each other, and results can be interpreted from completely different viewpoints. Comparing various indices from a tachogram, and combining statistical significance with physiological plausibility could...
Introduction: Although sickle cell disease (SCD) is characterized by significant microcirculatory dysfunction, it is not clear whether the mechanisms of regulation of the regulatory physiological phenomena associated with hemodynamic response during reactive hyperaemia post-occlusive test are is also affected in this population.
Objective: We soug...
Introduction: The Test of the Sustained Weight (TSW) is an isometric exercise, similar to hand grip, often used in Cuba to induce hemodynamic responses in order to identify individuals with cardiovascular hyperreactivity. However, the dynamic changes in the autonomic cardiovascular responses are not totally elucidated.
Objective: Determining the a...
The soy phosphatidylcholine, natural product used as nutritional supplement, presents multiple demonstrated biological actions, reason why it is very beneficial to treat patients with different disorders. Taking into account the above-mentioned the present investigation was carried out where some aspects of interest are exposed, aimed at diffusing...
The soy phosphatidylcholine, natural product used as nutritional supplement, presents multiple demonstrated biological actions, reason why it is very beneficial to treat patients with different disorders. Taking into account the above-mentioned the present investigation was carried out where some aspects of interest are exposed, aimed at diffusing...
The diverse influences as regards prevention presently XXI century, among those that are, the education and the art, they are erected as an unavoidable exponent of the work against the drugs consumer and their undesirable effects. In fact the operation of the Cinema Club Sara Gomez of the Ability of Medicine No.1, stimulates, by means of the debate...
Exploration activity cardivascular autonomic nervous system is essential in understanding the psychophysiological phenomena that subyancen in deepening the hypnotic state. In order to evaluate the activity of the autonomic nervous system cardivascular in different states of hypnotic depth a crossover study was conducted in 19 healthy subjects (19.7...
Pulse transit time (PTT) is a simple, non-invasive measurement and an appropriate parameter for stress measurement, but few quantitative data are available describing the factors which influence PTT. Objective: The aim of this study was to investigate beat-to-beat the relationship between time-frequency heart rate variability, the cardiac interval (...
A descriptive and cross-sectional study of 265 adults (101 men and 164 women) of the Medicine Faculty No. 1 in Santiago de Cuba, was carried out from September to October, 2014, aimed at determining the equations for the height estimate and verifying if those that were validated in adults of other nationalities have applicability in this population...
The application of methods for the detection of clinical points of interest of the pulse wave it allows the
obtaining of parameters like the index of rigidity and of reflection, facilitating in to evaluate the vascular effects of the aging, hypertension, rigidity and atherosclerosis, for that is necessary to determine the localization of the onset...
The Test of the Sustained Weight (PPS), it uses the isometric exercise to induce hemodynamic modifications of the cardiovascular system. This maneuvers it allows to identify the cardiovascular hyperreactivity that constitutes a factor of risk for the arterial Hypertension. Objective: To determine the variations of Arterial Tension after the applica...
A transverse analytic study in 22 athletes of the Sub-23 baseball Team in preparatory period and 22 students of one year of medicine between February-March of the present year in the Laboratory of Basic Biomedical Sciences of the University of Medical Sciences of Santiago de Cuba. With the objective of identifying variations in the athletes trainin...
The involved neural bases were studied in the generation of the auditory steady state response, obtained by stimulation with 40 hertz multiple frequency amplitude modulate tones, for which a high space resolution registration protocol was designed, the Bayes`method was applied to estimate their neurogenerators and restrictions were previously defin...
La aplicación del Potencial Evocado Auditivo de Tallo Cerebral (PEATC) con maniobras de rotación cervical, en
el diagnóstico de la insuficiencia vertebrobasilar se ve limitado por falta de estandarización de sus valores. Se realizó un estudio experimental en una muestra de 20 sujetos sanos entre 18 y 25 años con el objetivo de determinar el efecto...