Miguel Ángel Prieto Lage

Miguel Ángel Prieto Lage
University of Vigo | UVIGO · Department of Analytical and Food Chemistry

Food Science and Technology

About

345
Publications
62,307
Reads
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3,263
Citations
Introduction
(1) The field of Food Chemistry and Food Technology, in which he has acquired a broad knowledge on the: 1.a) characterization of bioactive compounds in food and biological samples by advanced analytical techniques; 1.b) development of new natural food products enriched with bioactive compounds and valorisation of food by-products. (2) The field of Bioinformatics and Chemical Engineering, focused in the response of bioactive compounds (antioxidant, antimicrobial, antitumoral, etc), enzymatic resp
Education
September 2005 - September 2007
IT Sligo
Field of study
  • Environmental Science and Technology
September 2005 - September 2007
University of Vigo
Field of study
  • Food and Technology
September 2002 - June 2005
University of Vigo
Field of study
  • Engineering

Publications

Publications (345)
Article
Full-text available
In systems with several effectors, the results of dose-response (DR) experiments are usually assessed by checking them against two hypotheses: independent action (IA) and concentration addition (CA). Both are useful simplifications, but do not represent the only possible responses, and avoid to a large extent the analysis of the interactions that a...
Article
NOEC and LOEC (no and lowest observed effect concentrations, respectively) are toxicological concepts derived from analysis of variance (ANOVA), a not very sensitive method that produces ambiguous results and does not provide confidence intervals (CI) of its estimates. For a long time, despite the abundant criticism that such concepts have raised,...
Article
The oxidant action implies interfering in an autocatalytic process in which no less than five chemical species are present (oxygen, oxidizable substrate, radicals, antioxidants and oxidation products) furthermore, reactions of first and second order can take place and interactions can occur at several levels of the process. The common and incorrect...
Article
Full-text available
The development of convenient tools for describing and quantifying the effects of standard and novel therapeutic agents is essential for the research community, to perform more precise evaluations. Although mathematical...
Poster
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The continuous increased resistance of pathogenic microorganisms to antibiotics is a serious public health problem worldwide. In the last decades, numerous studies have been focused on exploring and developing effective natural additives with antimicrobial potential based on natural matrices such as plants and new strategies to prevent this multi-r...
Article
The food industry has recently been under unprecedented pressure due to major global challenges, such as climate change, exponential increase in world population and urbanization, and the worldwide spread of new diseases and pandemics, such as the COVID-19. The fourth industrial revolution (Industry 4.0) has been gaining momentum since 2015 and has...
Article
"Económicos" are traditional Portuguese pastry products; although their production is low-cost, their nutritional value is equally low. Since it is a widely consumed product in the Trás-os-Montes region, it is important to add value to it without making significant changes to the traditional recipe. Thus, this work has the main objective to increas...
Article
Full-text available
Macroalgae have been recently used for different applications in the food, cosmetic and pharmaceutical industry since they do not compete for land and freshwater against other resources. Moreover, they have been highlighted as a potential source of bioactive compounds. Red algae (Rhodophyta) are the largest group of seaweeds, including around 6000...
Article
Full-text available
The production of citrus juice generates a large quantity of by-products, which are often discarded or used for animal feed. However, several studies have shown its richness in valuable compounds, namely organic acids. Thus, this work intended to valorize orange and lime peels as renewable sources of citric acid. An experimental design combining fi...
Article
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Fisetin (Fis), quercetin (Que), and myricetin (Myr) are flavonols with similar structure but different number of hydroxyl groups. The present research focused on the anti-inflammatory effect of these three flavonols in lipopolysaccharide-stimulated RAW264.7 cells. The number and site of hydroxyl group in flavonols obviously affected their anti-infl...
Conference Paper
Full-text available
Commonly used antibiotics use multiple administrations for providing a continuous bac-tericidal effect but can increase systemic toxicity, as well as lead to bacterial drug resistance [1,2]. The use of plant-based antibacterial compounds in combination with conventional antibiotics to treat drug-resistant infections could be an alternative to overc...
Article
Full-text available
Brown macroalgae are a potential source of natural pigments. Among them, Undaria pinnatifida is recognized for its high concentration of fucoxanthin (Fx), which is a pigment with a wide range of bioactivities. In this study, three independent parameters were optimized for conventional heat extraction (CHE) to maximize the recovery of Fx from Undari...
Conference Paper
Full-text available
Nowadays, medicinal plants have different uses since they can play an important role in the design of modern medicines and new healthy foods. Although their consumption is not high, these plants are attributed pharmacological properties with beneficial properties such as antioxi-dant, anti-inflammatory, or antimicrobial, among others [1]. The study...
Conference Paper
Full-text available
Ascophyllum nodosum (Linnaeus) Le Jolis is a brown alga from the Fucaceae family and the unique species from the Ascophyllum genus. This brown alga is an edible macroalga from the North Atlantic Ocean, commonly found on the European northwestern coast. High-value bioactive molecules such as pigments, polyphenols, and phlorotannin [1,2] have been fo...
Conference Paper
Full-text available
The increased resistance of pathogenic microorganisms to a wide range of antibiotics has driven recent research efforts towards exploring and developing effective preservatives with better potential and new strategies to prevent this multi-resistance. Many of these studies have been on natural matrices such as plants [1]. This is in line with consu...
Article
Background The food industry constantly searches for natural derived bioactive molecules with preventive and therapeutic effects using innovative and sustainable strategies. Fig production and processing generate a considerable amount of by-products (leaves, pulp, peels, seeds, and latex) with limited commercial exploitation and negative impact on...
Article
Full-text available
Quercetin is evidently unstable in Dulbecco's modified Eagle's medium (DMEM) at 37°C. However, the underlying mechanism of this instability is not clear yet. The stability and new degradation products of quercetin in DMEM at 37°C were investigated via in UPLC‐MS‐MS analysis. With increasing incubation time, quercetin formed various degradation prod...
Article
Drying is one of the foremost and important steps during the processing of agricultural crops, medicinal plants and herbs to preserve their properties. The present review provides a detailed overview regarding the effect of drying techniques on the physio-chemical properties (microstructure, color, aroma composition) and bioactive compounds (phenol...
Article
The growing consumers’ concern for possible long-term adverse effects of artificial molecules commonly used in food industry has led to an increased interest in natural products. At the same time, there is a demand for a more eco-sustainable use of natural matrices, which justifies the search for byproducts to be explored in the development of nove...
Poster
Full-text available
In recent decades, the interest of compounds with antioxidant properties has increased due to their involvement in biological systems and their implicit functions in a variety of chronic disorders. The genus Camellia is a genus rich in antioxidant compounds, so products derived from camellias such as teas and oils have been used in a traditional wa...
Article
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Meat constitutes one the main protein sources worldwide. However, ethical and health concerns have limited its consumption over the last years. To overcome this negative impact, new ingredients from natural sources are being applied to meat products to obtain healthier proteinaceous meat products. Algae is a good source of unsaturated fatty acids,...
Poster
Full-text available
Type 2 diabetes mellitus is a complex metabolic disorder described by hyperglycemia and glucose intolerance. It is considered a new pandemic and its control involves numerous challenges[1]. Currently, the most common treatments consist of the use of oral hypoglycemic agents and insulin, treatments that have shown side effects(cardiovascular problem...
Poster
Full-text available
Medicinal plants have been traditionally used throughout time as therapeutic treatments. These plants possess different compounds with antioxidant, anti-inflammatory and antimicrobial properties of industrial interest. In particular, the plants Achillea millefolium L., Arnica montana L., Calendula of icinalis L., Chamaemelum nobile L. All. and Tara...
Conference Paper
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Agroindustry generates different types of waste every year, among which are food suitable for human consumption, but without commercial value since they do not meet the strict marketing parameters. In this sense, the Food and Agriculture Organization of the United Nations (FAO) estimates that food losses reach 1,300 million tons, 44% corresponding...
Conference Paper
Full-text available
Sargassum muticum is an invasive brown macroalga in Galicia (Spain). Thus, exploitation of this biomass for the extraction of bioactive compounds could be an interesting strategy to add value to food supplements and functional foods. Among these compounds, fucoxanthin (Fx) has been gaining attention for its promising biological activities such as a...
Conference Paper
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Current research has shown that oily fish, specifically pelagic species like blue shark (Pri-onace glauca), shortfin mako (Isurus oxyrinchus), swordfish (Xiphias gladius) and bluefin tuna (Thunnus thynnus), are a rich source of essential nutrients like proteins (15-21%), lipids (0.5-3.3%), carbohydrates, vitamins A and D and minerals, like calcium...
Conference Paper
Full-text available
The scarcity of natural resources and a higher incidence of diseases related to inappropriate eating habits have focused research on the search for food and nutraceutical products with functional properties that are respectful of the environment. Agro-industrial by-products are a profitable source for obtaining bioactive compounds, with various bio...
Conference Paper
Full-text available
The scarcity of natural resources and a higher incidence of diseases related to inappropriate eating habits have focused research on the search for food and nutraceutical products with functional properties that are respectful of the environment. Agro-industrial by-products are a profitable source for obtaining bioactive compounds, with various bio...
Conference Paper
Full-text available
Sargassum muticum is an invasive brown macroalga and several attempts have been made to control and eradicate this species with little success because its time consuming and costly. Thus, exploitation of this biomass for the extraction of bioactive compounds could be an interesting strategy to add value to food supplements and functional foods [1]....
Article
Full-text available
Algae are underexplored resources in Western countries and novel approaches are needed to boost their industrial exploitation. In this work, eight edible seaweeds were subjected to their valorization in terms of nutritional characterization, thermochemical properties, and bioactive profile. Our results suggest that seaweeds present a rich nutrition...
Poster
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EcoChestnut project offers an innovative vocational training process to support the development of organic chestnut production in Europe. Its main output is an online comprehensive and tailored training course on organic chestnuts farming and products manufacturing. Why do we want to teach about chestnut production? Chestnut cultivation has a long...
Article
Full-text available
Fish and other seafood products are essential dietary components that are highly appreciated and consumed worldwide. However, the high perishability of these products has driven the development of a wide range of processing, preservation, and analytical techniques. This development has been accelerated in recent years with the advent of the fourth...
Article
: Fish and other seafood products are essential dietary components that are highly appreciated and consumed worldwide. However, the high perishability of these products has driven the development of a wide range of processing, preservation, and analytical techniques. This development has been accelerated in recent years with the advent of the fourt...
Article
Full-text available
Currently, agricultural production generates large amounts of organic waste, both from the maintenance of farms and crops (agricultural wastes) and from the industrialization of the product (food industry waste). In the case of Actinidia cultivation, agricultural waste groups together leaves, flowers, stems and roots while food industry by-products...
Article
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In response to the increased popularity of medicinal plants, a number of conservation groups are recommending the investigation on poorly characterized and widely distributed species, as it is the case of camellias. In particular, Camellia japonica L. is a widespread species found in Galicia (NW Spain), where it has been largely exploited with orna...
Article
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Brown algae are ubiquitously distributed in the NW coastline of the Iberian Peninsula, where they stand as an underexploited resource. In this study, five solvents were applied to the extraction of pigments from nine brown algae, followed by their determination and quantification by HPLC-DAD. A total of 13 compounds were detected: Six were identifi...
Article
Full-text available
Background Antibiotic resistance is one of the current threats to human health, forcing the use of drugs that are more noxious, costlier, and with low efficiency. There are several causes behind antibiotic resistance, including over-prescription of antibiotics in both humans and livestock. In this scenario, researchers are shifting to new alternati...
Article
Microalgae, as a photosynthetic autotrophic organism, contain a variety of bioactive compounds, including lipids, proteins, polysaccharides, which have been applied in food, medicine, and fuel industries, among others. Microalgae are considered a good source of marine lipids due to their high content in unsaturated fatty acid (UFA) and can be used...
Article
Full-text available
Seaweeds are a typical food of East-Asian cuisine, to which are alleged several beneficial health effects have been attributed. Their availability and their nutritional and chemical composition have favored the increase in its consumption worldwide, as well as a focus of research due to their bioactive properties. In this regard, seaweed proteins a...
Article
Full-text available
Sizeable scientific evidence indicates the health benefits related to phenolic compounds and dietary fiber. Various phenolic compounds-rich foods or ingredients are also rich in dietary fiber, and these two health components may interrelate via non-covalent (reversible) and covalent (mostly irreversible) interactions. Notwithstanding, these interac...
Article
BACKGROUND Common purslane (Portulaca oleracea) and annual ryegrass (Lolium rigidum) are important infesting weeds of field crops. Herbicides are mostly used for weed suppression, while their environmental toxicity and resistance in weeds against them demand considering alternative options, such as the use of allelopathic crops for weed management....
Article
Dihydromyricetin has shown many bioactivities in cell level. However, dihydromyricetin was found to be highly instable in cell culture medium DMEM. Here, the underlying degradation mechanism was investigated via UPLC-MS/MS analysis. Dihydromyricetin was mainly converted into its dimers and oxidized products. At lower temperature, dihydromyricetin i...
Article
Full-text available
Muscle foods and their products are a fundamental part of the human diet. The high protein content found in muscle foods, as well as the high content of essential amino acids, provides an appropriate composition to complete the nutritional requirements of humans. However, due to their special composition, they are susceptible to oxidative degradati...
Chapter
The oil industry is continuously evolving by the application of innovative tools and ingredients towards more effective, safe, natural and eco-friendly solutions to satisfy the claims of customers. Currently, packaging involves the use of a great diversity of materials ranging from different types of plastics to very diverse kinds of biodegradable...
Article
3D food printing is an emerging technology developed to facilitate the life of consumers and food enterprises. This technology allows to obtain any type of new foods according to our wishes. It is possible to develop a food with the exact nutritive value necessary for our body, with the most benefiting nutrients we want, or without any ingredients...
Chapter
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Recently, there has been an increasing interest in health-promoting products which are also natural and safe for consumption because the consumer market has been searching for a healthy lifestyle. This global market trend has driven the food industry to invest in developing innovative products containing bioactive components. Flavonoids are a group...
Chapter
Bioactive compounds are usually described as molecules that can be found in small quantities in food and other natural matrixes that can represent an extra-nutritional contribution to the diet due to their related health effects. Membrane technology is an emerging method aimed at purifying different ingredients which has received considerable atten...
Chapter
Full-text available
The application of natural colorants is increasing in the food industry because they are considered safer and healthier than some synthetic pigments. Natural colorants can improve the organoleptic properties of foodstuffs, provide additional benefits such as enhance their nutritional value and/or extend shelf-life. Plants, fungi, bacteria or algae...
Chapter
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Freeze-drying–based encapsulation involves the generation of an emulsion solution formed by the target compound and the encapsulating materials to later convert them into microcapsules applying the freeze-drying technique. Microcapsules are aimed to contain diverse ingredients such as active biomolecules, cells, or other materials. Later, the micro...
Chapter
Full-text available
Encapsulation involves the incorporation of food ingredients, enzymes, cells, drugs, or other materials in small capsules. This process consists of surrounding tiny particles with a coating layer conformed of a homogeneous or heterogeneous matrix, to produce small capsules. Therefore, it is a useful tool to fortify foods with bioactive molecules an...
Preprint
The application of natural colorants is increasing in the food industry because they are considered safer and healthier than some synthetic pigments. Natural colorants can improve the organoleptic properties of foodstuffs, provide additional benefits such as enhance their nutritional value and/or extend shelf-life. Plants, fungi, bacteria or algae...
Article
Full-text available
Background: The valorization of by-products is currently a matter of great concern to improve the sustainability of the food industry. High quality by-products derived from the food chain are omega-3 (ω3) fatty acids (FA), being fish the main source of docosahexaenoic (DHA) and eicosapentaenoic (EPA) acids. The search for economic and sustainable s...
Article
Full-text available
Background World-wide aquaculture represents a very important sector capable of supplying huge amounts of animal protein. However its relevance has proportionally augmented its waste generation. In Europe, the geographical constitution of Galicia has prompted the instauration of many aquaculture-based systems along its coasts. Indeed aquaculture me...