Michelle Tew

Michelle Tew
University of Melbourne | MSD · Health Economics Unit, Centre for Health Policy, Melbourne School of Population And Global Health

MPharm; MPH; PhD

About

25
Publications
1,454
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274
Citations

Publications

Publications (25)
Article
Objectives To assess comparative effectiveness and temporal changes in quality of life (QOL) outcomes after revascularisation, major lower extremity amputation (MLEA), and conservative management (CM) in chronic limb-threatening ischemia (CLTI). Data Sources MEDLINE, EMBASE, PsycINFO, CINAHL, and WOS databases. Review Methods A systematic review...
Article
Objective: To review quality of life (QOL) instruments for chronic limb-threatening ischemia (CLTI) patients and informal carers, and their use in QOL and cost-utility analysis (CUA) studies. Background: CLTI is a global health problem with significant morbidity affecting patients and informal carers. QOL is increasingly measured for holistic ou...
Article
Background Management of neutropenic fever in high-risk haematology patients is challenging; there are often few localising clinical features, and diagnostic tests have poor sensitivity and specificity. We aimed to compare how [¹⁸F]flurodeoxyglucose ([¹⁸F]FDG)-PET-CT scans and conventional CT scans affected the guidance of antimicrobial management...
Article
Objective To review and describe the available literature on cost-utility analysis of revascularisation and non-revascularisation treatment approaches in chronic limb-threatening ischemia. Methods A systematic review was performed on cost-utility analysis studies evaluating revascularisation (open surgery or endovascular), major lower extremity am...
Article
Background: Structural uncertainty can affect model-based economic simulation estimates and study conclusions. Unfortunately, unlike parameter uncertainty, relatively little is known about its magnitude of impact on life-years (LYs) and quality-adjusted life-years (QALYs) in modeling of diabetes. We leveraged the Mount Hood Diabetes Challenge Netw...
Article
Introduction Home-based treatment of febrile neutropenia (FN) in children with cancer with oral or intravenous antibiotics is safe and effective. There are limited data on the economic impact of this model of care. We evaluated the cost-effectiveness of implementing an FN programme, incorporating home-based intravenous antibiotics for carefully sel...
Preprint
INTRODUCTION Home-based treatment of low-risk febrile neutropenia (FN) in children with cancer with oral or intravenous antibiotics is safe and effective. There are limited data on the economic impact of this model of care. We evaluated the cost-effectiveness of implementing a low-risk FN program, incorporating home-based intravenous antibiotics, i...
Article
Full-text available
Background Cancer patients are at significant risk of developing sepsis due to underlying malignancy and necessary treatments. Little is known about the economic burden of sepsis in this high-risk population. We estimate the short- and long-term healthcare costs of care of cancer patients with and without sepsis using individual-level linked-admini...
Article
Full-text available
PurposeAs patient-reported outcome measures (PROMs) are increasingly integrated into clinical practice, there is a need to translate collected data into valuable information to guide and improve the quality and value of patient care. The purpose of this study was to investigate health-related quality-of-life (QoL) trajectories in the 5 years follow...
Article
Objectives The cardiovascular outcomes challenge examined the predictive accuracy of 10 diabetes models in estimating hard outcomes in 2 recent cardiovascular outcomes trials (CVOTs) and whether recalibration can be used to improve replication. Methods Participating groups were asked to reproduce the results of the Empagliflozin Cardiovascular Out...
Article
Background. There is growing evidence that quality of life (QoL) has a strong association with mortality. However, incorporation of QoL is uncommon in standard survival modeling. Methods. Using data extracted from a registry of patients undergoing total knee replacement (TKR), the impact of incorporating QoL in survival modeling was explored using...
Article
Full-text available
Improved understanding of quality-of-life (QoL) outcomes can provide valuable information on intervention effectiveness and guide better patient care. The aim of this study was to examine whether QoL trajectories differ between patients with and without diabetes and identify to what extent patient characteristics are related to poor QoL outcomes af...
Article
Objective The management of low-risk febrile neutropenia (FN) patients through ambulatory programs has demonstrated comparative safety and effectiveness to in-patient strategies. However, there is limited evidence of benefits of changing practice, particularly on a national scale. The aim of this study was to estimate costs and benefits of the prog...
Article
Full-text available
Transparency in health economic decision modelling is important for engendering confidence in the models and in the reliability of model-based cost-effectiveness analyses. The Mount Hood Diabetes Challenge Network has taken a lead in promoting transparency through validation with biennial conferences in which diabetes modelling groups meet to compa...
Article
Background The inclusion of future medical costs in cost-effectiveness analyses remains a controversial issue. The impact of capturing future medical costs is likely to be particularly important in patients with cancer where costly lifelong medical care is necessary. The lack of clear, definitive pharmacoeconomic guidelines can limit comparability...
Article
Full-text available
Infection and sepsis are common problems in cancer management affecting up to 45% of patients and are associated with significant morbidity, mortality and healthcare utilisation. Objective To develop and implement a whole of hospital clinical pathway for the management of sepsis (SP) in a specialised cancer hospital and to measure the impact on pa...
Article
Full-text available
Objectives: The Eighth Mount Hood Challenge (held in St. Gallen, Switzerland, in September 2016) evaluated the transparency of model input documentation from two published health economics studies and developed guidelines for improving transparency in the reporting of input data underlying model-based economic analyses in diabetes. Methods: Part...
Article
Full-text available
Objectives To investigate associations between maternal body mass index (BMI) at delivery (using pregnancy-specific BMI cut-off values 5 kg/m² higher in each of the WHO groups) and clinical, theatre utilisation and health economic outcomes for women undergoing caesarean section (CS). Design A prospective multicentre observational study. Setting S...
Technical Report
Full-text available
The purpose of this study is to describe variations in mortality across Federal Electorates based on the 2013 boundaries. Like most countries, Australia displays significant geographic variation in mortality which is strongly correlated with levels of socioeconomic disadvantage. Some urban/regional electorates have mortality ratios that are 30% gre...
Article
Full-text available
A recent study demonstrated widespread substitution of analog for human insulin and rising out-of-pocket costs in privately insured people with type 2 diabetes in the United States.1 Medicaid reimbursements have increased for both human insulin and more costly analog insulins.2 Although studies have described per-person changes in excess medical sp...
Article
Full-text available
Objective The aim of the present study was to quantify and understand the utilisation of linked hospital data for research purposes across Australia over the past two decades.MethodsA systematic review was undertaken guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2009 checklist. Medline OVID, PsycINFO, Emb...

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