Michelle Murphy

Michelle Murphy
University College Cork | UCC · Department of Medicine

About

129
Publications
21,067
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974
Citations
Citations since 2016
83 Research Items
499 Citations
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Introduction
Skills and Expertise

Publications

Publications (129)
Article
Full-text available
Poor oral health (OH) is a risk factor for systemic disease and lower quality of life (QoL). Patients with inflammatory dermatologic/rheumatologic diseases report more oral discomfort, dry mouth, and periodontal disease than controls. Medications used to treat these conditions can also adversely affect OH. The aim was to assess the OH of patients w...
Article
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Background Atopic dermatitis (AD) is the most common chronic inflammatory skin condition in childhood. Most (50-60%) children with AD report sleep disturbance, which is secondary to itch, dry skin, inflammation, and abnormal circadian rhythm. Sleep is essential for brain development, learning, and growth. Sleep disruption in early life is associate...
Article
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Lichen sclerosus (LS) is a chronic inflammatory dermatosis predominantly affecting the anogenital region, which can have significant impact on quality of life. Burden of treatment (BOT) is defined as the workload of healthcare experienced by patients and consequences on well‐being. In this prospective study, 35 women with vulval LS completed a deta...
Article
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Misinformation is a worldwide threat and can lead to worse outcomes for patients with skin cancer. The aim of this study was to qualitatively assess the content of online misinformation related to skin cancer. Searches were performed via PubMed and Google using the terms “skin cancer” OR “melanoma” OR “non‐melanoma skin cancer” OR “SCC” OR “BCC” AN...
Article
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Acne vulgaris is an extremely common disorder of the pilosebaceous unit, typically manifest as a highly visible facial and upper trunk dermatosis, with teenagers most frequently affected. This cohort is markedly susceptible to misinformation, given their impressionable age, distress regarding their appearance, and high internet usage. This study ai...
Article
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Background Burden of treatment (BOT) is the workload of healthcare experienced by patients with chronic conditions and consequences on well-being. This study aimed to assess the BOT of atopic dermatitis (AD) on children and caregivers using mixed methods. Methods The quantitative component of this mixed methods study involved the Treatment Burden...
Article
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Psoriasis is a chronic, hereditary disease with a complex immunopathogenesis rendering it susceptible to misinformation. Misinformation related to psoriasis can have negative effects on both the public perception of psoriasis and patients’ knowledge of psoriasis. To characterize misinformation related to psoriasis available online, we performed a f...
Article
The COVID‐19 pandemic has required new ways of working in dermatology. 1 Men over 50 years of age are at higher risk of mortality from melanoma, potentially due to poorer engagement with awareness and prevention campaigns, and delayed presentation. 2 Skin cancer clinical nurse specialists (SCCNS) provide an essential role in education, guidance, an...
Article
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We describe the cases of two immunocompetent children who developed mucositis with oral, ocular, and genital involvement during acute COVID-19 illness. The pattern of mucosal involvement with no other cutaneous involvement was consistent with reactive infectious mucocutaneous eruption (RIME). No other intercurrent infections or new medications were...
Article
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To assess Irish dermatologists’ confidence with dermatology in patients with skin of colour (SOC), an online survey was distributed to all members of the Irish Association of Dermatology (IAD) by email. Half (50%) of respondents were ‘not confident’ or ‘not at all confident’ in diagnosing skin conditions and one‐third (33.9%) were ‘not confident’ o...
Article
Lichen sclerosus (LS) is a chronic inflammatory dermatosis that predominantly affects the anogenital region. The diagnosis of LS is a clinical diagnosis and a confirmatory biopsy is not always required if typical clinical features are present. A biopsy is recommended if the clinical presentation is atypical or if there is diagnostic uncertainty.¹ T...
Article
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by the formation of nodules, abscesses, and fistula at intertriginous sites. The skin-gut axis is an area of emerging research in inflammatory skin disease and is a potential contributory factor to the pathogenesis of HS. 59 patients with HS provided fecal samples, n...
Poster
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This study highlights a significant reduction in carbon emissions secondary to the wholesale adoption of teledermatology during the period of national lockdown. It also shows the considerable time saving afforded to patients by implementing teledermatology. We believe our data is representative of the environmental benefits that teledermatology cou...
Poster
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The beneficial effects of isotretinoin in treating acne vulgaris are mediated through reduced sebum production. Excessive xerosis at other sites can manifest as dermatitis, cheilitis, rhinitis sicca, and blepharitis. The presence of cyanoacrylates in adhesives may cause diagnostic confusion in patients who develop blepharitis following application...
Poster
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Our findings call into question the current mechanism of providing Sunscreen funding for OTR in Ireland. There is poor awareness of the scheme amongst Community Pharmacists (49%), as well as low levels of uptake, with only 29% having applied to the scheme on behalf of a patient. Considerable frustration is felt by Pharmacists, with issues involvin...
Article
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COVID‐19 has transformed healthcare delivery globally. The main benefits of teledermatology are reported to be patient convenience and resource efficiency. 1 The environmental benefits of teledermatology have rarely been considered. Our group has previously highlighted the environmental benefit of dermatology outreach clinics. 2 We performed a cros...
Article
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Misinformation is one of the greatest threats to global health. Atopic dermatitis (AD) is a common skin disorder with a complex multifactorial aetiology, rendering it susceptible to misinformation. Little is known about the content of misinformation regarding AD online. We performed a review of misinformation related to AD available online, via Pub...
Article
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Dear Editor, Misinformation has been a major global challenge in the COVID‐19 pandemic. Several therapies relevant to dermatology have been falsely touted as beneficial, including hydroxychloroquine
Article
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Lan et al recently highlighted the under‐representation of older adults in clinical trials of systemic therapies for atopic dermatitis (AD). Late‐onset AD is increasingly recognised in older adults. Spontaneous remission is uncommon with this phenotype. Existing drug treatments such as corticosteroids, methotrexate, ciclosporin, and azathioprine ar...
Article
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Full skin examination (FSE) may improve the detection of malignant melanoma (MM). The objective of this study was to assess the safety of targeted lesion examination (TLE) compared to FSE in our pigmented lesion clinic (PLC). Patients attending PLC were randomised in a 2:1 ratio to FSE (intervention) or TLE (standard care). Demographic details and...
Article
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Genito‐urinary medicine (GUM) is a high‐volume, outpatient‐based specialty, predominantly involving healthy young people. Our GUM clinic is the largest in south‐west Ireland, with a broad catchment area. We outline the changes made to optimise safety and enhance efficiency during the COVID‐19 pandemic.
Article
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Organ transplant recipients (OTR) have an increased risk of keratinocyte cancers (KC), with a standardised incidence ratio of 6.3 for squamous cell carcinoma and 3.2 for basal carcinoma observed among an Irish cohort. ¹ Sunscreen use reduces the rate of KC among OTR by reducing exposure to solar ultraviolet radiation. 2, 3, 4 High SPF sunscreen is...
Article
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Dermatological issues are uniquely represented among certain visually‐driven social media platforms, presumably owing to the impact of skin‐health on the self‐esteem and outward appearance.¹ From a dermatology health‐promotion perspective, familiar platforms (SnapchatTM, InstagramTM)2,3 have been evaluated; TikTokTM is yet to be explored.
Article
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“All’s changed, changed utterly” – WB Yeats The COVID‐19 pandemic has had a monumental impact on healthcare delivery. Dermatology is a high‐volume, outpatient‐based, visual specialty, with complex patients and therapies. We summarise the adaptations in a dermatology department in Cork, Ireland, to enhance safety and streamline practice (Figure 1).
Article
Full-text available
Lichen sclerosus (LS) is a chronic inflammatory dermatosis that predominantly affects the anogenital region. Potential complications of vulvar LS include scarring, loss of architecture and vulvar squamous cell carcinoma (SCC). It has been suggested that individualised treatment regimens with long‐term topical corticosteroid (TCS) may modify the cou...
Poster
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The arrival of Covid-19 in early 2020 posed a unique challenge for Dermatology, a largely outpatient based and highly visual specialty. We, a large Dermatology Department based in the south of Ireland, recognised that a dramatic reduction in face-to-face interaction must be delivered on a tight timeline to ensure patient and staff safety. The resp...
Article
The arrival of Covid-19 in early 2020 posed a unique challenge for Dermatology, a largely outpatient based and highly visual specialty. We, a large Dermatology Department based in the south of Ireland, recognised that a dramatic reduction in face-to-face interaction must be delivered on a tight timeline to ensure patient and staff safety. The resp...
Article
Full-text available
The Haemangioma Investigator Group has published guidance on management of infantile haemangiomas (IH) during the COVID19 pandemic, advising tele-triage or virtual visits to stratify risk. Our centre in Ireland has co-ordinated a national electronic photo-triage system since November 2016 to facilitate rapid assessment and urgent treatment of infan...
Article
Alden et al assert isotretinoin and alitretinoin are contraindicated in nut allergic patients unless tested using the proposed protocol. We feel this is an unsupported step, limiting treatment options for adolescents with two very common conditions: nut allergy and acne. The index case’s eye and lip swelling occurring very late (12 hours) after iso...
Article
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Covid‐19 has resulted in unprecedented global disruption. As this global pandemic persists with no end in sight, we must not ignore its impact on undergraduate medical education. Dermatology undergraduate exposure is variable, limited and often suboptimal. It has been shown that medical students and qualified doctors are not adequately confident in...
Conference Paper
Lichen sclerosus (LS) is a chronic inflammatory dermatosis that predominantly affects the anogenital region. First line treatment is with topical clobetasol propionate 0.05%. Vulval LS is associated with a risk of progression to vulval squamous neoplasia, which is estimated to occur in approximately 1-5% of patients.1 It has been shown that individ...
Article
The Covid 19 outbreak has resulted in a reduction in cancer referrals. The Health Service Executive (HSE) in Ireland reports a reduction of 72% in pigmented lesion referrals since the pandemic began. This is concerning and likely reflects the fact that people are ignoring symptoms and delaying seeking medical advice due to fears related to Covid 19...
Article
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High sun protection factor (SPF) sunscreen is proven to reduce the incidence of non‐melanomatous skin cancer, particularly in populations at higher risk such as recipients of solid organ transplants. An Irish study has shown that SPF reimbursement schemes can remove cost as a barrier to access to sun protection in populations at increased risk.
Research
The incidence of melanoma is increasing and this increase is projected to continue.1 In Ireland, the incidence of melanoma is 20 per 100,000 population and accounts for 159 deaths per year. 2 This increased incidence is largely due to earlier detection of thin melanomas.3 However, this has not resulted in a reduction in incidence of thick melanomas...
Article
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Going viral: doctors must combat fake news in the fight against Covid-19 Dear Editor “Dúirt bean liom go ndúirt bean léi – a woman told me that a woman told her” (old Irish proverb) The Covid-19 pandemic is unprecedented in our lifetime. The general public has been overwhelmed with information related to the novel coronavirus. In 2020, information...
Article
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Aim To compare the relative efficiencies of skin excisions in primary and secondary care. Methods We compared the benign: malignant ratio for specimens referred by General Practice, General Surgery and the Skin Cancer Service to the regional pathology laboratory over one month. We used cost minimization analysis to compare the relative efficiencies...
Article
An 11‐year old girl presented with a 2‐month history of an erythematous stripe affecting her forehead in the right paramedian area (Figure 1). There was no associated skin atrophy or thickening, or hair loss to the scalp and eyebrows. The child was otherwise well and there was no family history of autoimmune disease. Thermography images were non‐di...
Article
Aim Our aim was to review cases of melanoma diagnosed histologically in UHK in 2016 and to compare them to cases of melanoma nationally and in Kerry. Methods For each patient we recorded age, Breslow depth, and shortest distance to travel by car and travelling time (without traffic) to the South Infirmary Victoria University Hospital (SIVUH) from t...
Article
Background Although considered as a first‐group carcinogen, indoor tanning is a common practice in Europe. Euromelanoma is a pan‐European skin cancer prevention campaign. Objectives To compare several European countries in terms of the prevalence and determinants of sunbed use. Methods Participants in the Euromelanoma campaigns filled in question...
Article
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The incidence of melanoma is increasing in Ireland and worldwide with higher rates of increase in Irish men (5% per year) compared to women (2.3% per year). Fortunately, overall mortality rates are not growing to the same extent especially in women, where mortality rates have flattened. Irish males, however, tend to present at a later stage with th...
Article
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Article
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Background: Hidradenitis suppurativa (HS), a chronic inflammatory disease that affects apocrine gland-bearing skin, has a significant impact on patient quality of life. Estimates of the epidemiologic prevalence of HS are highly variable, and clinical data on disease characteristics and patient burden of disease remain limited. Objective: The pri...