Michelle Gaines

Michelle Gaines
Spelman College · Department of Chemistry & Biochemistry

PhD

About

8
Publications
561
Reads
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88
Citations
Citations since 2017
1 Research Item
51 Citations
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201720182019202020212022202302468101214
201720182019202020212022202302468101214
201720182019202020212022202302468101214
Introduction
Dr. Gaines’s research is themed around designing and characterizing the surface chemical properties of synthetic and natural polymer systems. They will be used to develop multifunctional biomaterial substrates for regenerative medicine, cancer treatment, and personal care products.
Additional affiliations
March 2015 - January 2016
Georgia Institute of Technology
Position
  • PostDoc Position
September 2011 - September 2014
Georgia Tech Research Institute
Position
  • PostDoc Position

Publications

Publications (8)
Article
Full-text available
Significance Decoupling stiffness, pore size, and cell infiltration is a critical hurdle in biomaterials design. Here, by adding ultrasoft colloidal hydrogels to polymerizing fibrin, the particles are driven into a percolated three-dimensional tunnel-like structure throughout the fibrin network. The colloidal particles remain embedded, in stark con...
Article
As research on the rational design of targeted drug delivery vehicles continue to expand, cell movement is a model system to emulate when designing synthetic systems. Cell migration is a central phenomenon that supports morphogenesis, regeneration, and wound healing. Cell migration can also physiologically contribute pathologically through cancer m...
Conference Paper
Current rechargeable lithium-ion batteries contain anodes made of graphite. They are most often used for powering small devices such as cell phones and laptop computers, because they are cost-effective, have a sufficient theoretical reversible storage capacity (~372 mAh/g), and exhibit a long battery life. Although graphite anodes are adequate for...
Conference Paper
Our world is using radioactive materials to solve a vast number of complex problems such as developing nuclear power programs for achieving practical renewable energy resources, diagnosing and treating infectious diseases, sterilizing food products, and creating and disposing nuclear and chemical weapons of mass destruction (WMD). Portable, stable...
Article
Block copolymers remain one of the most extensively investigated classes of polymers due to their abilities to self-organize into various nanostructures and modify polymer/polymer interfaces. Despite fundamental and technological interest in these materials, only a handful of experimental phase diagrams exist due to the laborious task of preparing...
Article
Full-text available
Incorporation of nanoparticles composed of surface-functionalized fumed silica (FS) or native colloidal silica (CS) into a nanostructured block copolymer yields hybrid nanocomposites whose mechanical properties can be tuned by nanoparticle concentration and surface chemistry. In this work, dynamic rheology is used to probe the frequency and thermal...
Article
Lithium-ion batteries composed of silicon-decorated carbon nanotube (CNT) anodes were developed. The columbic efficiency between the measured specific capacity during charging and discharging was about 98%, evidencing strong consistency between the charging and discharging measurements. The Li+ storage capacity ranged from a maximum of 160 mAh/g to...
Article
Full-text available
Although block copolymer motifs have received considerable attention as supramolecular templates for inorganic nanoparticles, experimental observations of a nanostructured diblock copolymer containing inorganic nanoparticles—supported by theoretical trends predicted from a hybrid self-consistent field/density functional theory—confirm that nanopart...

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Projects

Projects (2)
Project
Humans across the globe have small phenotypic variances reflected in our outer appearance, including skin tone, hair type, size, and body shape. Understanding the surface chemical properties that govern hair texture and curl pattern are of particular interest to the Gaines Research Lab because it will lead toward designing better personal care products for healthy textured hair maintenance. In addition to conducting original research on the material properties of hair, Dr. Gaines is developing courses for students to take and learn about the science that govern the unique material properties of their hair. The program will add to Spelman College’s legacy of being a global leader in producing culturally inclusive thought-leaders. The goals of the Gaines Lab are achieved by marrying Polymer Synthesis, Materials Science, Cell Biology & Spectroscopy.
Project
Responsive biocompatible microgel polymer networks are the materials being developed into 3D biomimetic substrates that accurately match the indigenous 3D physical chemical properties of the microenvironment experienced by targeted cells and tissues. These new materials will have the potential to optimize cell culture output for tissue regeneration and probe malignant cell behavior in diseased tissues.