Michele Baldoni

University of Miami | UM · Department of Mechanical and Aerospace Engineering

The aim of this study was to quantitatively analyze the mechanical change of spinal segments (disc, muscle, and ligament) at various postures under microgravity using a full-body musculoskeletal modeling approach. Specifically, in the lumbar spine, the vertebra were modeled as rigid bodies, the intervertebral discs were modeled as 6-degree-of-freed...

The objective of this study was to quantitatively analyze the effect of lumbar spinal muscle atrophy on the compressive (perpendicular to the upper surface of the disc) and shear (parallel to the upper surface of the disc in the anterior-posterior direction) forces change on lumbar intervertebral discs using a full body musculoskeletal modeling app...

The fixed charge density (FCD) in the intervertebral disc (IVD) matrix is essential for its capacity of absorbing water, particularly during overnight bed rest. However, the FCD decreases with IVD degeneration, reducing the disc propensity to swell and the related convective transport of molecules across the IVDs. The objective of this study was to...