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Michel Thibaudon

Michel Thibaudon
RNSA · Aerobiology

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291
Publications
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Publications

Publications (291)
Article
Introduction (contexte de la recherche) Depuis des décennies, les mesures des pollens dans l’air sont réalisées grâce à des capteurs dynamiques (aspirant 10L/min) situés en position de fond sur des toits. Si cette méthodologie répondant à la norme Européenne EN 17868, correspond parfaitement aux besoins des réseaux pour fournir une information sur...
Preprint
Background: Allergic rhinitis (AR) is a major non-communicable disease that affects the health-related quality of life (HRQoL) of patients. AR is significantly related to asthma also affecting HRQoL. However, data on HRQoL and symptom control in AR patients with comorbid asthma are lacking. Objective: To assess the differences of symptom control an...
Article
Introduction: Pollen and fungal spore concentrations in outdoor air are partly dependent on atmospheric conditions. Since the climate is changing, there is a growing body of research on the effects of climate change on aeroallergens. The present article provides a rapid review of this literature, highlighting the points of agreement, but also draw...
Article
The Poaceae family is composed of 12,000 plant species. Some of these species produce highly allergenic anemophilous pollen grains (PGs). Phleum pratense pollen grains (PPPGs) emerged as a model for studies related to grass allergy. The biochemical composition of allergenic PGs has not yet been fully described despite potential health effects of PG...
Article
Full-text available
This study presents the results of a Europe-wide training and Quality Control (QC) exercise carried out within the framework of the European Aerobiology Society’s QC Working Group. The main aim of this exercise was to examine the feasibility of carrying out a QC exercise for fungal spore monitoring in Europe, using a similar methodology to the one...
Article
Introduction La hausse des niveaux de CO2 et le changement climatique peuvent entraîner un certain changement de l’aire géographique de certaines espèces végétales, ainsi qu’une augmentation de la photosynthèse. Beaucoup de plantes réagissent en conséquence avec une croissance et une reproduction accrues et peut-être des rendements de pollen plus é...
Article
Introduction Les herbacées regroupent toutes les plantes qui ont une partie ligneuse très peu ou pas développée. On trouve ces plantes partout : en ville, en bordure de routes ou de chemins, dans les prés, en forêt, etc. Elles sont aussi parfois appelées « mauvaises herbes » ou adventices. La saison des pollens d’herbacées commence en mai avec les...
Article
Introduction Espèce exotique envahissante, l’ambroisie à feuille d’armoise (Ambrosia artemisiifolia L.) constitue un enjeu de santé publique important en raison de son pollen fortement allergisant. Historiquement présente en Rhône-Alpes, la plante a aujourd’hui envahi les zones voisines. Nous présentons ici une estimation du nombre de personnes all...
Article
Introduction Ambrosia artemisiifolia est une plante de la famille des Asteraceae. C’est une espèce annuelle, dont le maintien dans un environnement donné est lié à sa capacité de reproduction. Il s’agit d’une espèce exotique envahissante originaire d’Amérique du Nord, capable de se reproduire sous nos latitudes (45°N) et de produire une grande quan...
Article
Full-text available
Pollen exposure weakens the immunity against certain seasonal respiratory viruses by diminishing the antiviral interferon response. Here we investigate whether the same applies to the pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is sensitive to antiviral interferons, if infection waves coincide with high airborne pol...
Article
Background Pollen food allergy syndrome (PFAS) is a frequently underdiagnosed disease due to diverse triggers, clinical presentations, and test results. This is especially relevant in geographic areas with a broad spectrum of pollen sensitization, such as Southern Europe. Objectives To elucidate similarities and differences ofPFAS in nine Southern...
Article
Full-text available
Background The analysis of mobile health (mHealth) data has generated innovative insights into improving allergic rhinitis control, but additive information is needed. A cross-sectional real-world observational study was undertaken in 17 European countries during and outside the estimated pollen season. The aim was to collect novel information incl...
Article
En France, depuis plus de trente-cinq ans, l’information sur le risque d’allergie lié à l’exposition au pollen fait appel à l’utilisation de capteurs spécifiques. Le réseau de surveillance aérobiologique, aujourd’hui connu sous le sigle RNSA, s’est progressivement constitué à partir de 1984 et il compte à présent environ 80 capteurs « de fond » de...
Article
Full-text available
Patients suffering from Seasonal Allergic Rhinitis (SAR) in Southern Europe are often difficult to diagnose due to polysensitization to many pollens and overlapping pollination periods. Pollen calendars and pollen concentration curves are used by allergists to perform a diagnostic approach related to pollen exposure times. However, in Mediterranean...
Article
Pollens are responsible for allergic rhinitis, conjunctivitis, and asthma. The incidence of these diseases, which have adversely impacted the social and professional lives of people who are allergic to pollen, has tripled in the past 25 years. Official institutes, health care institutions, public interest groups, and mainstream news media provide p...
Article
Full-text available
Background: The monitoring of bioaerosol concentrations in the air is a relevant endeavor due to potential health risks associated with exposure to such particles and in the understanding of their role in climate. In this context, the atmospheric concentrations of bacteria were measured from January 2018 to May 2020 at Saclay, France. The aim of th...
Article
Introduction Originaire d’Amérique du Nord, l’Ambroisie à feuille d’armoise (Ambrosia artemisiifolia) a été introduite accidentellement en France en 1863. Puis l’ambroisie s’est répandue sur les bords de route et les berges (Rhône, Loire.). Ce n’est qu’en 1970 que son rôle a été mis en évidence dans des cas de pollinose à Lyon [1]. Avec des données...
Article
Introduction La hausse des niveaux de CO2 et le changement climatique peuvent entraîner un certain changement de l’aire géographique de certaines espèces végétales, ainsi qu’une augmentation de la photosynthèse. Beaucoup de plantes réagissent en conséquence avec une croissance et une reproduction accrues et peut-être des rendements de pollen plus é...
Article
Full-text available
Invasive alien species (IAS) can substantially affect ecosystem services and human well-being. However, quantitative assessments of their impact on human health are rare and the benefits of implementing IAS management likely to be underestimated. Here we report the effects of the allergenic plant Ambrosia artemisiifolia on public health in Europe a...
Article
Full-text available
Background: Temporal ecological studies have shown that outdoor moulds are associated with severe asthma exacerbations, as emergency department visits or hospitalisations. The aim of this was to assess the associations between daily sales of short-acting β2-agonists (SABA), a specific and frequent treatment for control of mild asthma exacerbations...
Book
Full-text available
Chercheurs et spécialistes des laboratoires publics et privés se sont mobilisés pour centraliser et synthétiser, dans ce nouveau cahier, les effets du changement climatique sur la santé en région Provence-Alpes-Côte d’Azur et proposer des actions pour en limiter les conséquences. Pour citation : Les cahiers du GREC-SUD édités par l’Association pou...
Article
Full-text available
Background: The effectiveness of allergen immunotherapy (AIT) in seasonal and perennial allergic rhinitis (AR) depends on the definition of pollen exposure intensity or time period. We recently evaluated pollen and symptom data from Germany to examine the new definitions of the European Academy of Allergy and Clinical Immunology (EAACI) on pollen...
Article
Résumé En France, depuis plus de 35 ans, l’information sur le risque d’allergie lié à l’exposition au pollen fait appel à l’utilisation de capteurs spécifiques. Le réseau de surveillance aérobiologique, aujourd’hui connu sous le sigle RNSA, s’est progressivement constitué à partir de 1984 et il compte à présent environ 80 capteurs « de fond » de ty...
Article
Background: Several studies have suggested an interaction between air pollution and pollen exposure with an impact on allergy symptoms. However, large studies with real-life data are not available. Objectives: In the POLLAR (Impact of Air POLLution in Asthma and Rhinitis) project, we investigated associations between major air pollutants (ozone...
Article
Résumé C’est devenu une évidence que le climat change et que cela peut affecter la santé humaine. En particulier, on s’attend à ce que le réchauffement climatique se répercute sur la pollinisation et augmente l’occurrence des allergies respiratoires. Cette étude a été réalisée sur 6 ou 7 sites français de surveillance aérobiologique, avec l’objecti...
Article
The emission parameterization is a crucial part of numerical pollen dispersion models. This paper shows that Artificial Neural Networks (ANNs) can substantially improve the performance of the Ambrosia pollen emission in numerical pollen dispersion models such as COSMO-ART. Based on simultaneous measurement of Ambrosia pollen concentrations and mete...
Article
Objective: The objective of this panel study was to document the relationship between exposure to cypress pollen and allergic symptoms. Methods: The study group included 47 patients with allergy to cypress pollen who completed a daily diary and a weekly evaluation of quality of life (QoL) during the cypress pollen season. Different patients were...
Article
Résumé But de l’étude L’objet de cette étude était de montrer comment l’implantation de différentes espèces végétales en ville peut contribuer à renforcer l’exposition des citadins au pollen et, de ce fait, accroître la prévalence des pollinoses. Matériel et méthodes Le travail a été réalisé sur quatre parcs intra-urbains de Lyon entre mars et ju...
Article
Full-text available
Airborne fungal spores (AFS) represent the major fraction of primary biological aerosol particles (PBAPs), and they are studied worldwide largely due to their important role within the Earth system. They have an impact on climate and human health, and they contribute to the propagation of diseases. As their presence in the air depends largely on st...
Article
Full-text available
Background and objectives: Respiratory allergies induced by allergenic pollen represent an important public health problem with increasing prevalence and severity in Europe. Romania has no aerobiology network and pollen measurements have been done for about ten years in the west region only. Materials and Methods: We established the first pollen mo...
Article
Objective: Many research papers have addressed the beneficial qualities of forests in promoting mental and physical health. However, we should also be clear that forest environments could have detrimental effects. Some of them, which are of allergic nature, have hitherto been largely neglected. Methods: A comprehensive literature search has allo...
Article
Full-text available
Oak pollen seasons are relatively unexplored in large parts of Europe despite producing allergens and being a common tree in both continental and northern parts. Many studies are concentrated only on the Iberian Peninsula. In this study, the seasonal pattern of oak pollen in Europe was analysed using 10 observation sites, ranging from Spain to Swed...
Article
Background Google Trends (GT), a Web‐based surveillance tool, explores the searching trends of specific queries via Google and is proposed to reflect the real‐life epidemiology of allergic rhinitis and asthma. However, the validation of GTs against pollen concentrations is missing at the country level. Objectives In the present study, we used GTs...
Article
Introduction Depuis plusieurs années, le nombre de personnes atteintes de pollinose ne cesse d’augmenter en France. De l’ordre de 20 % des enfants à partir de 9 ans et 30 % des adultes seraient concernées par les allergies aux pollens en France [1]. Méthodes Une étude a été réalisée de mars à juin 2018 sur différents parcs de la ville de Lyon afin...
Article
The effect of height on pollen concentration is not well documented and little is known about the near-ground vertical profile of airborne pollen. This is important as most measuring stations are on roofs, but patient exposure is at ground level. Our study used a big data approach to estimate the near-ground vertical profile of pollen concentration...
Conference Paper
This paper deals with the problem of counting the amount of pollen grains (density of pollen) in a view acquired on a daily basis by a dedicated device. The grains are stuck on a ribbon which is analyzed by a microscope. This task is currently performed by a human operator who has to analyze quite 300 microscopic slides representing 10% of the ribb...
Article
Résumé Le RNSA a participé à une étude européenne en 2015 et 2016 avec pour objectifs d’évaluer la quantité de pollen et la teneur en allergènes dans plusieurs jardins publics de Paris et de Lyon et sur la base des résultats obtenus, de formuler des recommandations en vue de protéger les personnes allergiques. La conclusion est qu’il y a dans ces p...
Article
Full-text available
Background: Ongoing climate change might, through rising temperatures, alter allergenic pollen biology across the northern hemisphere. We aimed to analyse trends in pollen seasonality and pollen load and to establish whether there are specific climate-related links to any observed changes. Methods: For this retrospective data analysis, we did an e...
Article
Full-text available
In many perennial wind‐pollinated plants, the dynamics of seed production is commonly known to be highly fluctuating from year to year and synchronised among individuals within populations. The proximate causes of such seeding dynamics, called masting, are still poorly understood in oak species that are widespread in the northern hemisphere, and wh...
Article
Full-text available
The study of the origin and dispersion processes associated with airborne pollen grains are important to understand due to their impacts on health. In this context, a Hirst-type spore trap was utilized over the period 2015–2018 to monitor ambient pollen grains at Saclay, France, a receptor site influenced by both clean air masses originating from t...
Article
Background: Clinical efficacy of pollen allergen immunotherapy (AIT) has been broadly documented in randomized controlled trials. The underlying clinical endpoints are analysed in seasonal time periods predefined based on the background pollen concentration. However, any validated or generally accepted definition from academia or regulatory authori...
Article
Full-text available
The North American common ragweed, Ambrosia artemisiifolia, which produces highly allergenic pollen, is invasive in different parts of the world, including Europe. In 2013, common ragweed in northern Italy was found attacked by another accidentally introduced species, the North American leaf beetle Ophraella communa, which is used for biological co...
Article
Full-text available
The drivers of spatial variation in ragweed pollen concentrations, contributing to severe allergic rhinitis and asthma, are poorly quantified. We analysed the spatiotemporal variability in 16-year (1995–2010) annual total (66 stations) and annual total (2010) (162 stations) ragweed pollen counts and 8 independent variables (start, end and duration...
Article
Full-text available
Background: Google Trends (GT) searches trends of specific queries in Google, which potentially reflect the real-life epidemiology of allergic rhinitis. We compared GT terms related to ragweed pollen allergy in American and European Union countries with a known ragweed pollen season. Our aim was to assess seasonality and the terms needed to perfor...
Article
Background Outdoor molds are classically associated with exacerbations of asthma. Objective The aim of the present paper was to examine nasal allergy morbidity by studying the short‐term relationship between mold spore exposure and daily sales of reimbursable anti‐allergic treatment in central France. Methods The relationship between daily change...
Article
Full-text available
Background Ambient air quality monitoring is a governmental duty that is widely carried out in order to detect non-biological (“chemical”) components in ambient air, such as particles of < 10 µm (PM10, PM2.5), ozone, sulphur dioxide, and nitrogen oxides. These monitoring networks are publicly funded and air quality data are open to the public. The...
Article
Introduction En France, l’information des patients allergiques ne se fait pas uniquement avec des comptes de pollen qui n’ont pas de signification réelle, mais avec le risque d’allergie dû à l’exposition au pollen. Méthodes Depuis plus de 20 ans, le Réseau national de surveillance aérobiologique (RNSA) mesure l’exposition pollinique dans les ville...
Article
Introduction Les particules d’origine biologique transportées par le vent, comme les pollens et les moisissures, sont présentes dans l’air parfois en quantités très importantes en fonction des saisons. Selon leur potentiel allergisant, ces particules peuvent provoquer des symptômes d’allergie chez les personnes sensibles : en Europe, 20 % de la pop...
Article
Introduction Les pollens d’arbres sont des facteurs déclenchants majeurs d’allergies respiratoires telles que la rhinoconjonctivite allergique (RA) et l’asthme (A). L’immunothérapie sublinguale (ITSL) est une option de traitement pour les patients qui en souffrent mais tous les patients admissibles ne se la voient pas proposer par leur médecin. Mé...
Article
Allergic diseases, including respiratory conditions of allergic rhinitis (hay fever) and asthma, affect up to 500 million people worldwide. Grass pollen are one major source of aeroallergens globally. Pollen forecast methods are generally site-based and rely on empirical meteorological relationships and/or the use of labour-intensive pollen collect...