Michael Young

Michael Young
University of Washington | UW

About

37
Publications
1,646
Reads
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820
Citations
Additional affiliations
December 2021 - March 2023
Google Inc.
Position
  • Clinical Scientist
March 2011 - March 2018
University of Washington
Position
  • PhD Student
March 2018 - December 2021
University of Washington
Position
  • Senior Fellow

Publications

Publications (37)
Article
Full-text available
Objectives To examine whether long-term air pollution exposure is associated with central hemodynamic and brachial artery stiffness parameters. Methods We assessed central hemodynamic parameters including central blood pressure, cardiac parameters, systemic vascular compliance and resistance, and brachial artery stiffness measures [including brach...
Article
Background: Ambient air pollution, including traffic-related air pollution (TRAP), increases cardiovascular disease risk, possibly through vascular alterations. Limited information exists about in-vehicle TRAP exposure and vascular changes. Objective: To determine via particle filtration the effect of on-roadway TRAP exposure on blood pressure a...
Preprint
Full-text available
Objectives To examine whether air pollution exposure is associated with central hemodynamic and brachial artery stiffness parameters. Methods We assessed central hemodynamic parameters, brachial artery stiffness measures [including brachial artery distensibility (BAD), compliance (BAC), and resistance (BAR)] using waveform analysis of the arterial...
Article
Full-text available
Background: Based on human and animal experimental studies, exposure to ambient carbon monoxide (CO) may be associated with cardiovascular disease outcomes, but epidemiological evidence of this link is limited. The number and distribution of ground-level regulatory agency monitors are insufficient to characterize fine-scale variations in CO concen...
Article
Exposure to ambient air pollution is the largest environmental source of global disease burden. Accurate assessment of air pollutant exposure at finely-resolved spatial and temporal scales is critical for valid estimation of health effects. Limitations of exposure assessment approaches include computational burden and unreliable or complex input da...
Article
Background: Population studies support the adverse associations of air pollution exposures with child behavioral functioning and cognitive performance, but few studies have used spatiotemporally resolved pollutant assessments. Objectives: We investigated these associations using more refined exposure assessments in 1,967 mother-child dyads from...
Article
Background: PM2.5 have been associated with weight change in animal models and non-pregnant populations. Evidence of associations between PM2.5 and gestational weight gain (GWG), an important determinant of course and outcomes of pregnancy, and subsequent birth outcomes is limited. Methods: The study was conducted among a subset of participants...
Article
Full-text available
Purpose of Review Epidemiological studies of short- and long-term health impacts of ambient air pollutants require accurate exposure estimates. We describe the evolution in exposure assessment and assignment in air pollution epidemiology, with a focus on spatiotemporal techniques first developed to meet the needs of the Multi-ethnic Study of Athero...
Article
Full-text available
Background: Limited data suggest air pollution exposures may contribute to pediatric high blood pressure (HBP), a known predictor of adult cardiovascular diseases. Methods: We investigated this association in the Conditions Affecting Neurocognitive Development and Learning in Early Childhood (CANDLE) study, a sociodemographically diverse pregnan...
Preprint
A fundamental problem in environmental epidemiology studies on the association of air pollution exposure with health outcomes is identifying exposure levels for individuals in a cohort study. Measurements are not made at each study participants place of residence, thus individual specific exposure levels are estimated using observations from regula...
Article
Background: Prenatal and early life air pollution exposure may impair healthy neurodevelopment, increasing risk of childhood behavioral disorders, but epidemiological evidence is inconsistent. Little is known about factors that determine susceptibility. Methods: Participants were mother-child dyads from the CANDLE study, an ECHO PATHWAYS Consort...
Article
Background: Limited evidence links air pollution exposure to chronic cough and sputum production. Few reports have investigated the association between long-term exposure to air pollution and classically defined chronic bronchitis. Objectives: Our objective was to estimate the association between long-term exposure to particulate matter (diamete...
Article
Full-text available
Background: Few epidemiologic studies have evaluated the effects of air pollution on risk of Parkinson's disease (PD). Objective: We investigated the associations of long-term residential concentrations of ambient particulate matter (PM) less than 10µm in diameter (PM10), less than 2.5µm in diameter (PM2.5), and nitrogen dioxide (NO2) in relatio...
Article
Epidemiological studies increasingly rely on exposure prediction models. Predictive performance of satellite data has not been evaluated in a combined land-use regression/spatial smoothing context. We performed regionalized national land-use regression with and without universal kriging on annual average NO2 measurements (1990-2012, contiguous U.S....
Article
Full-text available
Background: Some but not all past studies reported associations between components of air pollution and breast cancer, namely fine particulate matter ≤2.5 μm (PM2.5) and nitrogen dioxide (NO2). It is yet unclear whether risks differ according to estrogen receptor (ER) and progesterone receptor (PR) status. Methods: This analysis includes 47,591...
Article
Full-text available
Rationale: Limited prior data suggest an association between traffic-related air pollution and incident asthma in adults. No published studies assess the effect of long-term exposures to particulate matter less than 2.5 μm in diameter (PM2.5) on adult incident asthma. Objectives: To estimate the association between ambient air pollution exposure...

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