Michael Wink

• Prof. Dr.
• Professor (Full) at Heidelberg University

Report on birds recorded on Ornitho.de for Nordbaden and areas in HE and RLP for the months October 2024 til March 2025

Accurately predicting species’ responses to anthropogenic climate change is hampered by limited knowledge of their spatiotemporal ecological and evolutionary dynamics. We combine landscape genomics, demographic reconstructions, and species distribution models to assess the eco-evolutionary responses to past climate fluctuations and to future climat...

The Rock Bunting (Emberiza cia) occurs from the Iberian Peninsula to mountainous regions in Central Asia. In Europe, its centre of distribution lays in the Mediterranean region. A small subpopulation is found in Germany in rocky habitats (often with vineyards) along the rivers Middle Rhine, Nahe, Main, Moselle and Ahr. In this study, the German pop...

Pigeon pea is an important economic crop with medicinal and nutritional value. Unfortunately, pest infestation of leaves during postharvest storage seriously affects the quality of pigeon pea. Phytohormones play a crucial role in disease and pest defence by regulating the accumulation of specialized metabolites. Still, their impact on the postharve...

Many birds regard partitioning feeding and breeding resources as a strategy to escape competition and co-occurring breeding species. During the breeding season, breeding requirements are essential, yet the patterns and drivers of segregation between and within populations are poorly understood. We monitored the habitat use and chronology of the fou...

Summary of bird observations in Nordbaden from April to September 2024 190 pages

The leaf extract of Alnus rugosa (AR) together with the isolated compound baicalein 5,6‐dimethyl ether (BME) were investigated for their antioxidant, radical scavenging, antiaging, and neuroprotective properties using the Caenorhabditis elegans model. The stress resistance and antiaging potential of AR and BME were assessed in wildtype N2 and trans...

Every year, several hundred million birds cross the Mediterranean on their migration from Eurasia to their wintering quarters in Africa. As many migrants travel at night or at high altitudes, direct observations of bird migration are difficult and thus our information about migrating species, numbers and timing is incomplete. An indirect way to ass...

In light of the pivotal role of Artemia Leach, 1819 as food in larviculture and fisheries, it becomes imperative to continually reassess its resources and deepen our understanding of its species diversity. Such efforts are essential for the effective management of its commercial exploitation and the promotion of sustainable aquaculture activities....

The authors wish to emphasize that the experiments were simultaneously conducted with several plant species, and identical control groups were utilized for both articles (Phytomedicine (2017), doi:10 [...]

Report on birds seen in Nordbaden/ Baden-Württemberg during the winter 2023-2024

Increased reactive oxygen species and advanced glycation end products are often associated with human ageing and degenerative diseases. Biancaea sappan L serves as a medicinal plant and a healthy drinks ingredient in Java. However, the pharmacological investigation of the plant native to this island is still lacking in depth. In the current study,...

WINK M, COLE TCH, BURGOS-GALLARDO F (2024) FILOGENIA de las AVES (Neornithes) © Wink, Cole, Burgos-Gallardo 2024 (CC-BY) • sistemática, clasificación y características de Neornithes (Aves) • árbol hipotético basado en datos filogenéticos en Stiller et al. 2024 • las distancias de las ramas no reflejan lapsos de tiempo reales (tiempos de divergencia...

Simple Summary In this paper, we present the first diagnostic of the wintering birds in the wetlands of the Saïss plain and its adjacent Atlas Mountains (north–center of Morocco). The study revealed an unexpected diversity of bird species, for which we provide the population size, with their variations, over five years (2017–2018 to 2022–2023). Amo...

WINK M, COLE TCH (2024) AVES Phylogeny Poster »TREE o f BIRDS« © Wink, Cole 2024 (CC-BY) • systematics, classification and features of Neornithes (Aves) • hypothetical tree based on phylogenetic data • branch lengths deliberate, not reflecting true time spans (for approximate divergence times see Stiller et al. 2024 and Wu et al. 2024) • features a...

WINK M, COLE TCH, FREITAS GL, FERNANDES AM (2024) FILOGENIA das AVES (Neornithes) © Wink, Cole, Freitas, Fernandes 2024 (CC-BY) • árvore hipotética baseada em dados filogenéticos em Stiller et al. 2024 • comprimentos de ramificação deliberados, não refletindo extensões de tempo reais (para tempos de divergência veja Stiller et al. 2024 and Wu et al...

WINK M, COLE TCH (2024) »Stammbaum der Vögel« AVES Phylogenie Poster © Wink, Cole 2024 (CC-BY) • Systematik und Merkmale 40 anerkannter Ordnungen der Neornithes (Aves) • Hypothetischer Stammbaum entsprechend molekular-phylogenetischer Daten von Stiller et al. 2024 • Astlängen: willkürlich, ohne Zeitbezug (für Diversifikations-Zeiten siehe Stiller e...

Винк M, Коул ТКГ, Мудрик EA (2024) ФИЛОГЕНИЯ ПТИЦ (постер по филогении класса Aves) © Винк, Коул, Мудрик 2024 (CC-BY), Russian version of: WINK M, COLE TCH (2024) AVES Phylogeny Poster »TREE of BIRDS« • систематика, классификация и отличительные признаки веерохвостых птиц (Neornithes) • гипотетическое дерево, основанное на филогенетических данных •...

The Northern Wheatear (Oenanthe oenanthe) is a long-distance migratory bird that has become a model species for the study of the phenomenology and molecular aspects of avian migration. Here, we analysed transcriptomic data related to the lipid metabolism in the liver of wheatears during the development and termination of the migratory fattening. In...

Summary of bird observation in Nordbaden from April to September 2023

The eagles sensu lato are a polyphyletic group of large raptors represented in the Palearctic realm by 13 species belonging to two subfamilies: Aquilinae (true Eagles) and Haliaeetinae (Sea Eagles). Phylogenetic position of this group taxa at species level and above based on nuclear and mitochondrial markers is currently clarified (Mindell et al.,...

Citation: Agustini K, Kusumaningrum S, Firdayani, Sulfianti A, Wink M (2023) Estrogenic activity of Bryonia dioica Jacq. through in silico and in vitro studies on pS2 gene expression in the breast cancer cell line MCF-7. Pharmacia 70(4): 951-958. https://doi. Abstract Bryonia dioica is a member of the Cucurbitaceae that produces bioactive secondary...

A crude methanol extract of the roots of Allochrusa gypsophiloides (syn. Acanthophyllum gypsophiloides) (collected from the Tashkent region of Uzbekistan) was chemically characterised by UHPLC-ESI-QTOF-MS/MS analysis. The results indicate the presence of six major bisdesmosidic saponins derived from gypsogenin, gypsogenic and quillaic acids, includ...

It has been previously reported that a leaf extract of Psidium guajava L. (GV.E) can impart numerous health benefits that were attributed to its antioxidant and anti-inflammatory effects. Ethanol (EtOH, alcohol) misuse is a global health burden, with profound effects on the younger population. The toxic effects of EtOH, that are largely attributed...

Background Despite its widespread uses in Chinese and European medicine, Styphnolobium japonicum (Chinese scholar tree, formerly Sophora japonicum) has not been extensively investigated for its potential to protect against neurodegenerative processes and to promote resistance to oxidative stress. In this study, we evaluated the neuroprotective acti...

Zusammenfassung Gewalt ist im Tierreich weit verbreitet und tritt in der Auseinandersetzung zwischen unter-schiedlichen Arten, vor allem aber intraspezifisch, also innerhalb derselben Art auf. Die Knappheit von Ressourcen (Nahrung, Reviere, Paarungspartner) ist häufig ein Auslöser von Gewalt. Bei Ressourcenmangel setzt häufig ein Wettbewerb ein, de...

Anthologie Krieg, Konflikt & Solidarität

Lycorine, an isoquinoline alkaloid that exhibits against breast carcinoma effects. The present study was conducted to illustrate the underlying mechanisms of lycorine on breast carcinoma in vitro and in vivo. Tandem Mass Tag assay and Kyoto Encyclopedia of Genes and Genomes analysis revealed that 20 signaling pathways were closely related to tumori...

The increasing prevalence of antimicrobial resistance (AMR) in Staphylococcus aureus against commonly used antibiotics is a major global health issue. To prevent the emergence of AMR and maintain the desired therapeutic effect, the use of drug combinations in the therapeutic management of infections can be contemplated. This approach allows for the...

Breeding habitat loss and depletion of genetic diversity can have critically negative impacts on species, and especially so for habitat specialists. The Aquatic Warbler Acrocephalus paludicola is a threatened European songbird that breeds in fens, which have been lost and fragmented over centuries. We used microsatellite loci to perform a spatial a...

A potential role of berberine, a benzyl isoquinoline alkaloid, in cancer therapy is apparent. Its underlying mechanisms of berberine against breast carcinoma under hypoxia have not been elucidated. We focused on the doubt how berberine restrains breast carcinoma under hypoxia in vitro and in vivo. A molecular analysis of the microbiome via 16S rDNA...

Summary of bird observations in Nordbaden from October 21 to March 2022

Summary of bird observations in Nordbaden from October 2022 to March 2023

Summary of bird observations in Nordbaden from October 22 to March 2023

The genus Allochrusa (Caryophyllaceae) comprises nine species, which are native to Central Asia, Turkey, Iran, Afghanistan, and the Caucasus. They have been used in folk medicine and in the preparation of various sweets and detergents, especially in Asian countries. A diversity of secondary metabolites has been reported from the genus Allochrusa, i...

In submitting conference proceedings to Biology and Life Sciences Forum, the volume editors of the proceedings certify to the publisher that all papers published in this volume have been subjected to peer review administered by the volume editors [...]

Protein probes, including ultrafiltrates from the placenta (UPla) and lung (ULu) of postnatal rabbits, were investigated in premature senescent HEK293 and HepG2 cells to explore whether they could modulate cellular senescence. Tris-Tricine–PAGE, gene ontology (GO), and LC–MS/MS analysis were applied to describe the characteristics of the ultrafiltr...

Objectives: Nanoparticles can be employed to improve the therapeutic activity of natural products. Type 2 diabetes mellitus is a serious health condition that has spread like a "modern pandemic" worldwide. In the present study, we developed silver nanoparticles, AgNPs, with an aqueous extract from Balanites aegyptiaca to investigate their antioxid...

Previous studies have individually shown the antidiabetic potential of gamma conglutin (Cγ) and lupanine from lupins. Until now, the influence of combining both compounds and the effective dose of the combination have not been assessed. Moreover, the resulting gene expression profile from this novel combination remains to be explored. Therefore, we...

Olea europaea is an economically significant crop native to Mediterranean countries. Its leaves exhibit several biological properties associated to their chemical composition. The aqueous ethanolic extracts of olive leaves from twelve different cultivars were analyzed by high performance liquid chromatography coupled to photodiode array and electro...

Background The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled “International Natural Product Sciences Taskforce” (INPST) was established in 2018, to bring...

Pollution is a worldwide environmental risk. Arsenic (As) is an environmental pollutant with a major health concern due to its toxic effects on multiple body organs, including the brain. Humans are exposed to As through eating contaminated food and water or via skin contact. Salix species (willow) are plants with medicinal efficacy. Salix subserrat...

Introduction Cysteamine, a powerful endogenous antioxidant, is produced mostly by the vanin-1 with pantetheinase activity. With regard to glycemic, inflammatory, and redox factors, the current study sought to evaluate the association between the expression of the vanin-1 gene, oxidative stress, and inflammatory and iNOS signaling pathway in obese d...

North Africa houses many small populations of the Eurasian Reed Warbler Acrocephalus scirpaceus complex. Previous studies have shown that Reed Warblers belonging to the recently resurrected subspecies ambiguus inhabit Morocco, parts of SW Europe and Libya. Recent field work in the central Algerian Sahara was designed to close thegeographical gap an...

Background: The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled "International Natural Product Sciences Taskforce" (INPST) was established in 2018, to brin...

Background: The turtle dove is a migratory species that has suffered a rapid decline principally across its Northern ranges, despite pronounced conservation measures. Consequently, it has been categorized as ‘Near Threatened’ in Europe. Degradation of breeding habitats and a decrease in food resources are listed as principal causes of this decline....

In this study, we investigated the avian diversity and threatening factors in five peri-urban sites around Fez city (Morocco) for 2 years (2018–2019). The study hosted 131 avian species, including 64.88% breeding species, 19.84% migrant winterers, and 11.45% migrant breeders. Five species of conservation concern such as the vulnerable European turt...

Euclea divinorum Hiern is a medicinal plant widely distributed in the northeast parts of South Africa. This plant has been used to treat miscarriage and to alleviate gastrointestinal problems. It can also be used externally for the treatment of ulcers and gonorrhea. In this study, we investigated the phytochemical composition of E. divinorum leaf e...

Background: The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled “International Natural Product Sciences Taskforce” (INPST) was established in 2018, to brin...

The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled “International Natural Product Sciences Taskforce” (INPST) was established in 2018, to bring together i...

Multidrug resistance (MDR) is a leading cause for treatment failure in cancer patients. One of the reasons of MDR is drug efflux by ATP-binding cassette (ABC) transporters in eukaryotic cells especially ABCB1 (P-glycoprotein). In this study, certain novel 1,2,5-trisubstituted benzimidazole derivatives were designed utilising ligand based pharmacoph...

Potential health benefits of tea has attracted significant scientific and public attention worldwide. Tea polyphenols are considered as natural promising complementary therapeutical agents for neurodegenerative diseases. However, the anti-neurodegeneration or anti-aging activities of oolong tea polyphenols have not been investigated. The current st...

New Findings from Natural Substances present the state-of-the-art and future prospects for the application of biomolecules in the pharmaceutical, agricultural, food and industrial sectors. The book presents eight reviews contributed by more than twenty experts on interesting natural substances, and plant sources, that serve as sources of natural re...

Anthologie Die vier Elemente

Essential oils (EOs) and their individual volatile organic constituents have been an inherent part of our civilization for thousands of years. They are widely used as fragrances in perfumes and cosmetics and contribute to a healthy diet, but also act as active ingredients of pharmaceutical products. Their antibacterial, antiviral, and anti-inflamma...

Flamingos are highly mobile waterbirds that can be found in tropical and subtropical regions worldwide. The large distribution range of flamingos, the inaccessibility of most of their breeding sites and the lack of species-specific molecular markers, such as microsatellites, have hampered population genetics studies of these majestic birds. Here, w...

The Chukar Partridge (Alectoris chukar, Galliformes) is one of the most important game birds in its native range, spanning from the Balkans to eastern Asia, and the regions of Europe, North America and New Zealand where it was introduced. Previous studies found two main genetic lineages of the species forming an eastern and a western clade. Chukar...

Partial mitochondrial cytochrome b gene sequences reveal two deeply differentiated mtDNA lineages in anoa dwarf buffaloes (Bubalus depressicornis) from the studbook herd in European zoos. Three matrilinear lineages of lowland anoas (depressicornis type) contributed three rather similar sequence haplotypes, but one remarkably distinct haplotype was...

The metabolic syndrome (MS) is a multifactorial syndrome associated with a significant economic burden and healthcare costs. MS management often requires multiple treatments (polydrug) to ameliorate conditions such as diabetes mellitus, insulin resistance, obesity, cardiovascular diseases, hypertension, and non-alcoholic fatty liver disease (NAFLD)...

Die Evolution des Lebens, also biologische Evolution, wird in diesem Kapitel aus verschiedenen Perspektiven behandelt. Dieser Artikel bietet einen Überblick über den Stand des Wissens um die drei gültigen Artkonzepte, die Entstehung von Arten, Meilensteine der Evolution des Lebens in der Erdgeschichte, unterschiedliche Geschwindigkeiten von Evoluti...

Summary of bird observations in Nordbaden from April - September 2022

Extra-pair copulation (EPC) occurred in most socially monogamous bird species. The mechanisms leading to the frequent occurrence of extra-pair offspring (EPO, EPY) in socially monogamous couples, as well as the ‘function’ of EPC, are the subjects of strong debates and raise many unanswered questions. We studied the relationship between extra-pair p...

We previously annotated the phytochemical constituents of a root extract from Ximenia americana var. caffra and highlighted its hepatoprotective and hypoglycemic properties. We here extended our study on the leaf extract and identified its phytoconstituents using HPLC-PDA-ESI-MS/MS. In addition, we explored its antioxidant, antibacterial, and antia...

Plants produce a diversity of plant secondary metabolites (PSMs), which function as defense chemicals against herbivores and microorganisms but also as signal compounds. An individual plant produces and accumulates mixtures of PSMs with different structural features using different biosynthetic pathways. Almost all PSMs exert one or several biologi...

This is the first complete breeding record of this owl and it also confirms the taxonomic status of the Greyish Eagle Owl Bubo cinerascens through the sequencing of the mitochondrial cytochrome b gene by using the owls from The Gambia, Mali, Ethiopia and South Africa.

The Red-backed Shrike (Lanius collurio) is a medium-sized, carnivorous passerine, occurring throughout the western Palearctic. As with numerous other bird species, its numbers are declining, mainly due to anthropogenic factors. Therefore, revealing the population structure and genetic diversity is paramount in ensuring the survival of the species....

Ethnopharmacological relevance The genus Warburgia (family Canellaceae) is widely distributed over Afrotropical and Neotropical realms. Traditionally, W. salutaris (G. Bertol.) Chiov., and other Warburgia species are used as anti-inflammatory, antimalarial, antimicrobial, and for wound healing, and treating several skin complaints as well. Specific...

Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary metabolite in many plant taxa. EA content is considerable in pomegranate (Punica granatum L.) and in wood and bark of some tree species. Structurally, EA is a dilactone of hexahydroxydiphenic acid (HHDP), a dimeric gallic acid derivative, produced mainly by hydr...