Michael Onyema

Michael Onyema
King's College Hospital NHS Foundation Trust · Department of Diabetes

About

9
Publications
264
Reads
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5
Citations
Citations since 2017
7 Research Items
5 Citations
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Publications

Publications (9)
Article
Full-text available
Paraneoplastic syndromes denote rare but notable phenomena caused by the tumour mediated release of bioactive substances. Peptide and non-peptide hormone causes are explored with a particular focus on pathogenesis, symptoms, diagnosis and treatment. Early detection and management of paraneoplastic syndromes can improve morbidly and mortality; defin...
Preprint
Paraneoplastic syndromes denote rare but notable phenomena caused by the tumour mediated release of bioactive substances. Peptide and non-peptide hormone causes are explored with a particular focus on pathogenesis, symptoms, diagnosis and treatment. Early detection and management of paraneoplastic syndromes can improve morbidly and mortality; defin...
Article
Glucocorticoids are known to affect calcium balance but are not thought to cause clinically significant hypocalcemia. This case adds to a list of isolated reports noting significant hypocalcemia developing post administration of glucocorticoids in a patient with known hypoparathyroidism, postulating PTH deficiency as a risk factor of decompensated...
Conference Paper
Full-text available
Case History Herein, we report the case of a 79-year-old male who presented acutely to A&E with recurrent episodes of symptomatic hypoglycaemia. A random glucose at presentation was low at 1.4 mmol/l and upon correction symptoms resolved. While hospitalized, he continued having episodes of symptomatic hypoglycaemia, requiring treatment with intrav...
Article
Full-text available
We report the case of a 79-year-old male with previous history of non-Hodgkin's lymphoma in remission, who presented acutely to the Accident and Emergency department with recurrent episodes of hypoglycaemia. At the time of presentation, a random glucose was low at 1.4mmol/l, which upon correction resolved his symptoms. In hindsight, the patient rec...

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Projects

Projects (2)
Project
Our team is assessing the long-term efficacy and safety of desiccated porcine thyroid extracts versus standard of care levothyroxine replacement therapy for patients with primary hypothyroidism. In this retrospective cohort study, we are critically and systematically appraising more than 10 year follow up data.
Project
A concise review of key pathophysiological mechanisms involved in the aetiopathogenesis of paraneoplastic syndromes and an update on current diagnostic methods.