Michael Onyema

King's College Hospital NHS Foundation Trust · Department of Diabetes

Paraneoplastic syndromes denote rare but notable phenomena caused by the tumour mediated release of bioactive substances. Peptide and non-peptide hormone causes are explored with a particular focus on pathogenesis, symptoms, diagnosis and treatment. Early detection and management of paraneoplastic syndromes can improve morbidly and mortality; defin...

Paraneoplastic syndromes denote rare but notable phenomena caused by the tumour mediated release of bioactive substances. Peptide and non-peptide hormone causes are explored with a particular focus on pathogenesis, symptoms, diagnosis and treatment. Early detection and management of paraneoplastic syndromes can improve morbidly and mortality; defin...

Glucocorticoids are known to affect calcium balance but are not thought to cause clinically significant hypocalcemia. This case adds to a list of isolated reports noting significant hypocalcemia developing post administration of glucocorticoids in a patient with known hypoparathyroidism, postulating PTH deficiency as a risk factor of decompensated...

Case History Herein, we report the case of a 79-year-old male who presented acutely to A&E with recurrent episodes of symptomatic hypoglycaemia. A random glucose at presentation was low at 1.4 mmol/l and upon correction symptoms resolved. While hospitalized, he continued having episodes of symptomatic hypoglycaemia, requiring treatment with intrav...

We report the case of a 79-year-old male with previous history of non-Hodgkin's lymphoma in remission, who presented acutely to the Accident and Emergency department with recurrent episodes of hypoglycaemia. At the time of presentation, a random glucose was low at 1.4mmol/l, which upon correction resolved his symptoms. In hindsight, the patient rec...