Michael I. Demidenko

Stanford University | SU

Empirical studies reporting low test–retest reliability of individual blood oxygen-level dependent (BOLD) signal estimates in functional magnetic resonance imaging (fMRI) data have resurrected interest among cognitive neuroscientists in methods that may improve reliability in fMRI. Over the last decade, several individual studies have reported that...

Empirical studies reporting low test-retest reliability of individual blood oxygen-level dependent (BOLD) signal estimates in functional magnetic resonance imaging (fMRI) data have resurrected interest among cognitive neuroscientists in methods that may improve reliability in fMRI. Over the last decade, several individual studies have reported that...

Interpreting the neural response elicited during task functional magnetic resonance imaging (fMRI) remains a challenge in neurodevelopmental research. The monetary incentive delay (MID) task is an fMRI reward processing task that is extensively used in the literature. However, modern psychometric tools have not been used to evaluate measurement pro...

Interpreting the neural response elicited during task functional magnetic resonance imaging (fMRI) remains a challenge in neurodevelopmental research. The monetary incentive delay (MID) task is a popular fMRI reward processing task that is extensively used in the literature. However, modern psychometric tools have not been used to evaluate measurem...

Exposure to community and individual level stressors during adolescence has been reported to be associated with increased substance use. However, it remains unclear what the relative contribution of different community- and individual-level factors play when alcohol and marijuana use become more prevalent during late adolescence. The present study...

The study of adolescent cognitive development has increased both in scope and depth in the decades since the germinal work by Inhelder and Piaget (1958) launched this research field. This chapter briefly reviews the conceptual history of the study of adolescent cognitive development, relevant once again as current theories evoke similar themes. An...

Increasing evidence demonstrates that environmental factors meaningfully impact the development of the brain (Hyde et al., 2020; McEwen and Akil, 2020). Recent work from the Adolescent Brain Cognitive Development (ABCD) Study® suggests that puberty may indirectly account for some association between the family environment and brain structure and fu...

Watching a speaker’s face improves speech perception accuracy. These benefits are owed, in part, to implicit lipreading abilities present in the general population. While it is established that lipreading can alter the perception of a heard word, it is unknown how information that is extracted from lipread words is transformed into a neural code th...

Intrauterine devices (IUDs) are the most-used reversible contraceptive method for women in the world, but little is known about their potential modulation of brain function, cognition, and behavior. This is disconcerting because research on other hormonal contraceptives, especially oral contraceptives (OCs), increasingly shows that exogenous sex ho...

Increasing evidence demonstrates that environmental factors meaningfully impact the development of the brain (Hyde et al., 2020; McEwen & Akil, 2020). Recent work from the Adolescent Brain Cognitive Development (ABCD) Study® suggests that puberty may indirectly account for some association between the family environment and brain structure and func...

This study examined how ethnic identity relates to large‐scale brain networks implicated in social interactions, social cognition, self‐definition, and cognitive control. Group Iterative Multiple Model Estimation (GIMME) was used to create sparse, person‐specific networks among the default mode and frontoparietal resting‐state networks in a diverse...

Adolescent risk-taking, including sensation seeking (SS), is often attributed to developmental changes in connectivity among brain regions implicated in cognitive control and reward processing. Despite considerable scientific and popular interest in this neurodevelopmental framework, there are few empirical investigations of adolescent functional c...

Adolescent risk-taking, including sensation seeking (SS), is often attributed to developmental changes in connectivity among brain regions implicated in cognitive control and reward processing. Despite considerable scientific and popular interest in this neurodevelopmental framework, there are few empirical investigations of adolescent network conn...

Sex hormones, especially androgens, contribute to sex and gender differences in the brain and behavior. Organizational effects are particularly important because they are thought to be permanent, reflecting hormone exposure during sensitive periods of development. In human beings, they are often studied with natural experiments in which sex hormone...

Ecological stress during adolescent development may increase the sensitivity to negative emotional processes that can contribute to the onset and progression of internalizing behaviors during preadolescence. Although a small number of studies have considered the link among the relations between ecological stress, amygdala reactivity and internalizi...

Introduction: Phenomena related to reward responsiveness have been extensively studied in their associations with substance use and socioemotional functioning. One important task in this literature is the Monetary Incentive Delay (MID) task. By cueing and delivering performance‐contingent reward, the MID task has been demonstrated to elicit robust...

[This is a Stage 2 Registered Report that is currently under review. Stage 1 was reviewed and accepted in March 2020 (https://osf.io/46yru)] Ecological stress during adolescent development may increase the sensitivity to negative emotional processes that can contribute to the onset and progression of internalizing behaviors during preadolescence. A...

Since the first neurodevelopmental models that sought to explain the influx of risky behaviors during adolescence were proposed, there have been a number of revisions, variations and criticisms. Despite providing a strong multi-disciplinary heuristic to explain the development of risk behavior, extant models have not yet reliably isolated neural sy...

Phenomena of positive valence with respect to reward responsiveness have been extensively studied in psychology. These constructs have been linked to dopaminergic pathways central to the literature on psychopathologies and development, and their measurement is a key interest in task-based fMRI. One such task, used for almost twenty years, is the Mo...

Since the first neurodevelopmental model that sought to explain the influx of risk behaviors during adolescence was proposed (Ernst, Pine, & Hardin, 2006), there has been a series of iterations, criticisms and revisions. Despite limited ecological validity, the models have been used to propose studies and interpret results without establishing clea...

Self-report and cognitive tasks of reward sensitivity and self-regulation have influenced several developmental models that may explain the heightened engagement in risk behaviors during adolescence. Despite some inconsistencies across studies, few studies have explored the convergent, discriminant, and predictive validity of self-report and cognit...

In the brief period since a preceding review in the Encyclopedia of Adolescence (Keating, 2011), overlaps in research on adolescent cognitive development, neurocognitive development, and developmental neuroscience have increased rapidly. Accordingly, this review addresses those related topics, although with a concentration on the cognitive aspects...

Objective: Urine drug testing (UDT) is increasingly performed as a means of identifying aberrant behavior that may be grounds for discontinuation of long-term opioid therapy (LTOT). Little is known, however, about the ways in which positive UDT results may differentially inform decisions to discontinue LTOT based on the type of substance for which...

Little is known about changes in pain intensity that may occur following discontinuation of long-term opioid therapy (LTOT). The objective of this study was to characterize pain intensity following opioid discontinuation over 12 months. This retrospective VA administrative data study identified N=551 patients nationally who discontinued LTOT. Data...

Performance difference on BART for self-reported binge drinking only, marijuana only or binge/mj adolescents.

Performance difference on Balloon Analogue Risk Task between self-reported 12-month alcohol only, marijuana only and combined alc/mj users.

Background: Little is known about pain care offered to patients discontinued from long-term opioid therapy (LTOT) by their prescriber due to aberrant behaviors versus other reasons. Objective: This study aimed to compare rates of non-opioid analgesic pharmacotherapy initiation and clinician referrals for non-pharmacologic pain treatment, complem...

Background: It is unclear whether substance use disorder (SUD) treatment is offered to, or utilized by, patients who are discontinued from long-term opioid therapy (LTOT) following aberrant urine drug tests (UDTs). Objective: To describe the proportion of patients who were referred to, and engaged in, SUD treatment following LTOT discontinuation...

Objective Little is known about patient outcomes following discontinuation of opioid therapy, which may include suicidal ideation (SI) and suicidal self-directed violence (SSV). The purpose of this study was to examine correlates of SI and non-fatal SSV in a sample of patients discontinued from long-term opioid therapy (LTOT). Method Five hundred-...

Several factors may accelerate opioid discontinuation rates, including lack of information about the long-term effectiveness of opioids for chronic pain, heightened awareness about opioid-related adverse events, closer monitoring of patients for opioid-related aberrant behaviors, and greater restrictions around opioid prescribing. Rates of disconti...

Multidisciplinary Pain Clinics (MPCs) follow a model of care that emphasizes managing pain to the extent the patient’s independence is restored and overall quality of life improved, rather than complete elimination of pain. Providers from various disciplines collaborate to develop a unique treatment plan consisting of various interventions to meet...