Michael Johnathan Charles Bray

Johns Hopkins Medicine | JHUSOM · Department of Psychiatry and Behavioral Sciences

Professional boxers and Mixed Martial Arts (MMA) fighters regularly sustain blunt force trauma to the head leading to Traumatic Brain Injury (TBI) and concussion; therefore, fighters are at high risk for chronic traumatic encephalopathy and neurodegenerative disease. Family history of dementia (fhD) may significantly modulate fighter response to TB...

Introduction: Traumatic brain injury (TBI) may alter dementia progression, although co-occurring neuropsychiatric symptoms (NPS) have received less attention. Originally designed to evaluate behavioral disruption prior to dementia diagnosis, the mild behavioral impairment (MBI) construct relates NPS to underlying neural circuit disruptions, with p...

Objective To complete a systematic review of the literature examining neuroimaging findings unique to co-occurring syndromal depression in the setting of TBI. Methods A PRISMA compliant literature search was conducted in PubMed (MEDLINE), PsychINFO, EMBASE, and Scopus databases for articles published prior to April of 2022. The database query yiel...

Neuroimaging is widely utilized in studying traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD). The risk for PTSD is greater after TBI than non-TBI trauma, and PTSD is associated with worse outcomes after TBI. Studying the neuroimaging correlates of TBI-related PTSD may provide insights into the etiology of both conditions and h...

Introduction Neuroimaging has been a highly utilized technique for studying traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) independently of one another, however, neuroimaging has increasingly been identified as a useful tool in better understanding TBI-related psychiatric conditions, such as PTSD. Objectives To complete a s...

Introduction Traumatic brain injury (TBI) may alter dementia progression, although co-occurring neuropsychiatric symptoms (NPS) have received less attention. The mild behavioral impairment (MBI) construct relates NPS to underlying neural circuit disruptions, representing an important area of inquiry regarding TBI and dementia. Objectives (1) to ex...

Introduction Sleep disturbances are common following traumatic brain injury (TBI) worsening morbidity and other neuropsychiatric symptoms. Post-TBI alterations in sleep architecture require further study. Objectives (1) To evaluate polysomnographic measures of sleep architecture in participants with history of TBI compared to controls and as meta-...

Background Predicted increases in suicide were not generally observed in the early months of the COVID-19 pandemic. However, the picture may be changing and patterns might vary across demographic groups. We aimed to provide a timely, granular picture of the pandemic's impact on suicides globally. Methods We identified suicide data from official pu...

Background Behavioral and emotional dyscontrol commonly occur following traumatic brain injury (TBI). Neuroimaging and electrophysiological correlates of dyscontrol have not been systematically summarized in the literature to date. Objective To complete a systematic review of the literature examining neuroimaging and electrophysiological findings...

Background Traumatic brain injury (TBI) can precipitate new-onset psychiatric symptoms or worsen existing psychiatric conditions. To elucidate specific mechanisms for this interaction, neuroimaging is often used to study both psychiatric conditions and TBI. This systematic review aims to synthesize the existing literature of neuroimaging findings a...

[This corrects the article DOI: 10.1093/braincomms/fcab026.].

Traumatic brain injury (TBI) is a common source of functional impairment among athletes, military personnel, and the general population. Professional fighters in both boxing and mixed martial arts (MMA) are at particular risk for repetitive TBI and may provide valuable insight into both the pathophysiology of TBI and its consequences. Currently, ef...

Psychosis is a rare, but particularly serious sequela of traumatic brain injury. However, little is known as to the neurobiological processes that may contribute to its onset. Early evidence suggests that psychotic symptom development after traumatic brain injury may co-occur with hippocampal degeneration, invoking the possibility of a relationship...

Introduction Individuals with moderate-severe traumatic brain injury (m-sTBI) experience progressive brain and behavioural declines in the chronic stages of injury. Longitudinal studies found that a majority of patients with m-sTBI exhibit significant hippocampal atrophy from 5 to 12 months post-injury, associated with decreased cognitive environme...

Introduction: Traumatic brain injury (TBI) may alter the course of neuropsychiatric symptom (NPS) onset during dementia development. The connection among TBI, NPS, and dementia progression is of increasing interest to researchers and clinicians. Methods: Incidence of NPS was examined in participants with normal cognition who progressed to all-ca...

This cross-sectional study analyzes trends in suicidality by race/ethnicity during the coronavirus disease 2019 (COVID-19) pandemic.

DESCRIPTION  Music therapy (delivered live by a trained music therapist) and music medicine (live or recorded music not delivered by a music therapist) are empirically supported interventions for the treatment of depression and anxiety, with emerging evidence of benefit for psychosis, and psychiatric symptoms in specific patient populations.  The...

Abstract Background and objective Educational achievement, particularly among youth, may mitigate risk of exposure to violence and negative related health outcomes such as crime and gang activity. Few studies to date have examined relationships between education and youth homicide. The authors hypothesized association between educational achievemen...

Traumatic brain injury (TBI) and Alzheimer’s disease (AD) bear a complex relationship, potentially increasing risk of one another reciprocally. However, recent evidence suggests post-TBI dementia exists as a distinct neurodegenerative syndrome, confounding AD diagnostic accuracy in clinical settings. This investigation sought to evaluate TBI’s impa...

It has long been established that fighting sports such as boxing and mixed martial arts can lead to head injury. Prior work from this group on the Professional Fighters Brain Health Study found that exposure to repetitive head impacts is associated with lower brain volumes and decreased processing speed in fighters. Current and previously licensed...

Traumatic brain injury (TBI) is characterized by a host of persisting mental health (cognitive and psychiatric), motor and neurological sequelae, including progressive, degenerative change in the hippocampi. This thesis postulates that hippocampal volume loss may contribute to the increased risk of psychotic disorder that is observed in this popula...

Objective: The symptomatology of post-injury psychosis suggests an etiology associated with degenerative change in the hippocampi. Progressive hippocampal decline post-TBI may contribute to dysregulation of dopaminergic networks implicated in psychosis. This study examines the novel hypothesis that hippocampal degeneration may contribute to the eti...

Objective: Traumatic brain injury (TBI) is fast becoming understood as an important factor in the etiology of homelessness, given the high prevalence of TBIs, and their frequent occurrence prior to the onset of homelessness. Specifically, it has been proposed that TBI exerts its detrimental impact through acquired cognitive/psychiatric sequelae of...